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1 ked reduction in platelet counts, and dengue hemorrhagic fever.
2 n virus is used to protect against Argentine hemorrhagic fever.
3 mptoms, such as hepatitis, encephalitis, and hemorrhagic fever.
4 oviruses, are the causative agents of severe hemorrhagic fever.
5 potential therapeutic agents to treat Lassa hemorrhagic fever.
6 each year, many of which develop into fatal hemorrhagic fever.
7 Filoviruses (Ebola and Marburg) cause severe hemorrhagic fever.
8 of which are filoviruses) that cause severe hemorrhagic fever.
9 rotective vaccine candidate against Bolivian hemorrhagic fever.
10 ease that sometimes leads to encephalitis or hemorrhagic fever.
11 us (MACV) is the causative agent of Bolivian hemorrhagic fever.
12 ment of vaccines or therapeutics for Marburg hemorrhagic fever.
13 rus (JUNV), the causative agent of Argentine hemorrhagic fever.
14 is an emerging zoonotic pathogen that causes hemorrhagic fever.
15 Ebolaviruses cause severe hemorrhagic fever.
16 om a rodent to humans and can lead to lethal hemorrhagic fever.
17 lavirus is an enveloped virus causing severe hemorrhagic fever.
18 ackground determines susceptibility to Ebola hemorrhagic fever.
19 uated vaccine for the treatment of Argentine hemorrhagic fever.
20 s (JUNV), the etiological agent of Argentine hemorrhagic fever.
21 zoonotic pathogens capable of causing fatal hemorrhagic fever.
22 ct humans and non-human primates, and causes hemorrhagic fever.
23 gic fever virus (CCHFV) is a cause of severe hemorrhagic fever.
24 uses responsible for dengue fever and dengue hemorrhagic fever.
25 ated with a cluster of human cases of severe hemorrhagic fever.
26 continent to cause epidemics of highly fatal hemorrhagic fever.
27 causative agents of dengue fever and dengue hemorrhagic fever.
28 hagic fever virus (SHFV) causes lethal viral hemorrhagic fever.
29 t Africa and responsible for severe cases of hemorrhagic fever.
30 vaccines against Lassa and other arenaviral hemorrhagic fevers.
31 tly asymptomatic infections to severe, viral hemorrhagic fevers.
32 may be useful in the treatment of arenavirus hemorrhagic fevers.
33 t of effective therapies to treat arenaviral hemorrhagic fevers.
34 ttenuated vaccine candidates for other viral hemorrhagic fevers.
35 surrogate small animal model for arenavirus hemorrhagic fevers.
36 zation clinical-investigation form for viral hemorrhagic fevers.
37 e as experimental vaccines for several viral hemorrhagic fevers.
38 agnostic replacement for the ELISA for viral hemorrhagic fevers.
39 anslation apparatus.IMPORTANCE Crimean-Congo hemorrhagic fever, a highly contagious viral disease end
41 s (JUNV) is the causative agent of Argentine hemorrhagic fever (AHF), a potentially deadly disease en
42 etiological agent responsible for Argentine hemorrhagic fever (AHF), activates an early innate immun
43 unin virus, the causative agent of Argentine hemorrhagic fever (AHF), is an arenavirus identified as
56 elop severe manifestations, including dengue hemorrhagic fever and shock syndrome, resulting in ~25,0
59 lular and molecular mechanisms of arenaviral hemorrhagic fever and suggests potential strategies for
60 Thus, IFN-I may play a prominent role in hemorrhagic fevers and other acute virus infections asso
61 the causative agent of dengue fever, dengue hemorrhagic fever, and dengue shock syndrome and is ende
65 disease severity and virulence in arenavirus hemorrhagic fever are largely unknown, particularly rega
66 GP1 glycoprotein from Junin virus (JUNV), a hemorrhagic fever arenavirus endemic in central Argentin
75 irus (MACV), the causative agent of Bolivian hemorrhagic fever (BHF), is a New World arenavirus that
77 rotect at-risk individuals against Argentine hemorrhagic fever, but it has not been licensed in the U
79 A)-approved vaccines are available to combat hemorrhagic fever caused by mammarenavirus infections in
81 he focus on vaccine development against this hemorrhagic fever-causing pathogen, and as a consequence
82 on mechanisms between arenaviruses and other hemorrhagic fever-causing viruses, such as Ebola, Marbur
83 laboratory tests available for Crimean-Congo hemorrhagic fever (CCHF) and their utility in diagnosis
89 uding 15 viruses (chikungunya, Crimean-Congo hemorrhagic fever [CCHF] virus, dengue, Ebola virus, Bun
91 plete resistance to lethal disease to severe hemorrhagic fever characterized by prolonged coagulation
93 ed data from the Sierra Leone National Viral Hemorrhagic Fever Database, contact tracing records, Ken
94 rus (JUNV), the causative agent of Argentine hemorrhagic fever, demonstrating the feasibility of usin
95 r decades, the gold-standard immunoassay for hemorrhagic fever detection has been the enzyme-linked i
96 enrollment in patients who developed dengue hemorrhagic fever (DHF) (n = 11), compared with the non-
97 hort of patients with dengue fever or dengue hemorrhagic fever (DHF) (n = 166) and controls (n = 149)
98 ut, in severe cases, life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS)
99 se, and it can cause life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS).
100 -B44 supertype was protective against dengue hemorrhagic fever (DHF) in secondary infections (odds ra
101 NNIg) is the greatest risk factor for dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS).
102 V-1-4) that causes Dengue fever (DF), Dengue hemorrhagic Fever (DHF) or Dengue shock syndrome (DSS).
103 develop the life-threatening diseases dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS).
105 range of symptoms: dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS)
106 ry dengue virus (DENV) infections and dengue hemorrhagic fever (DHF), the majority of secondary infec
109 enting as dengue fever (DF; mild) and dengue hemorrhagic fever (DHF; severe) and subjects with a nons
110 naviruses, chiefly Lassa virus (LASV), cause hemorrhagic fever disease in humans and pose serious pub
111 ral members of the Arenaviridae family cause hemorrhagic fever disease in humans and pose serious pub
114 athogens, since several of them cause severe hemorrhagic fever disease that is associated with high m
115 erent species, and some of them cause lethal hemorrhagic fever disease, this group of viruses has bee
116 Machupo viruses, can cause severe and deadly hemorrhagic fever diseases in humans, and there are limi
119 ssa fever virus, can cause severe and lethal hemorrhagic fever diseases with high mortality and morbi
120 sa virus (LASV), can cause severe and lethal hemorrhagic fever diseases with high mortality and morbi
121 amples from 70 patients with suspected Ebola hemorrhagic fever during a 2014 outbreak in Boende, Demo
123 zed by "abortion storms" in ruminants and by hemorrhagic fever, encephalitis, and blindness in humans
124 by a high rate of abortion in ruminants and hemorrhagic fever, encephalitis, or blindness in humans.
125 veloped filamentous RNA virus causing severe hemorrhagic fever, enters cells by macropinocytosis and
126 Marburg virus (MARV) infection is a lethal hemorrhagic fever for which no licensed vaccines or ther
127 unin virus, the causative agent of Argentine hemorrhagic fever, for high-throughput screening (HTS).
128 uses (NWAs) can cause severe and often fatal hemorrhagic fever, for which preventive and therapeutic
129 infrastructure for research regarding viral hemorrhagic fever, has received and cared for patients w
130 es for managing patients infected with viral hemorrhagic fevers have evolved as new information has b
134 es a severe and almost uniformly fatal viral hemorrhagic fever in Asian macaques but is thought to be
135 ) has caused highly fatal outbreaks of viral hemorrhagic fever in captive Asian macaque colonies.
136 rus, have caused sporadic outbreaks of viral hemorrhagic fever in captive macaque monkeys since the 1
137 African swine fever virus (ASFV) causes hemorrhagic fever in domestic pigs, presenting the bigge
139 y discovered Phlebovirus causing an emerging hemorrhagic fever in East Asia, with reported case fatal
141 a highly pathogenic virus that causes severe hemorrhagic fever in humans and is responsible for epide
143 us, are zoonotic pathogens that cause severe hemorrhagic fever in humans and nonhuman primates (NHPs)
144 avirus (SEBOV), cause severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs)
145 s (MARV) and Ebola virus (EBOV) cause severe hemorrhagic fever in humans and nonhuman primates (NHPs)
146 ongs to the virus family Filoviridae, causes hemorrhagic fever in humans and nonhuman primates that i
149 highly pathogenic viruses that cause severe hemorrhagic fever in humans and other mammals with high
151 (BDBV) is the etiological agent of a severe hemorrhagic fever in humans with a case-fatality rate ra
152 la virus causes sporadic outbreaks of lethal hemorrhagic fever in humans, but there is no currently a
157 rging zoonotic virus that causes often-fatal hemorrhagic fever in infected humans for which preventat
158 emorrhagic fever virus (SHFV) causes a fatal hemorrhagic fever in macaques but an asymptomatic, persi
159 layed a role in previous outbreaks of simian hemorrhagic fever in macaques, as has long been suspecte
161 (EBOV) causes a highly infectious and lethal hemorrhagic fever in primates with high fatality rates d
162 us is responsible for outbreaks of Argentine hemorrhagic fever in South America, where 5 million peop
165 The massive outbreak of highly lethal Ebola hemorrhagic fever in West Africa illustrates the urgent
166 Infections by these viruses can cause severe hemorrhagic fevers in humans and nonhuman primates with
172 are responsible for severe life-threatening hemorrhagic fevers in western Africa and South America.
173 the clinical hallmarks observed with Marburg hemorrhagic fever, including lymphopenia, thrombocytopen
174 opment of antiviral strategies against viral hemorrhagic fevers, including AHF, is one of the top pri
175 ment of antiviral strategies to combat viral hemorrhagic fevers, including Bolivian hemorrhagic fever
176 Several mammarenaviruses can cause deadly hemorrhagic fever infections in humans, with limited pre
179 able for clinical evaluation.IMPORTANCE EBOV hemorrhagic fever is one of the most lethal viral infect
182 viral hemorrhagic fevers, including Bolivian hemorrhagic fever, is one of the top priorities of the I
183 unin virus, the causative agent of Argentine hemorrhagic fever, it is licensed for use only in areas
184 has been shown to protect against Argentine hemorrhagic fever-like disease in marmosets infected wit
185 host cell surface receptor for all New World hemorrhagic fever mammarenaviruses-and mimics an importa
188 do not reproduce hallmark symptoms of Ebola hemorrhagic fever, neither delayed blood coagulation and
189 es, infected individuals can also experience hemorrhagic fever, neurological disorders, liver failure
190 h disease (CMTD) in humans, acts by blocking hemorrhagic fever New World arenavirus (NWA) entry into
194 from classical dengue fever to severe dengue hemorrhagic fever or dengue shock syndrome; however, the
195 ess annually, escalating to life-threatening hemorrhagic fever or shock syndrome in approximately 500
199 of vaccines and therapeutics to combat viral hemorrhagic fevers remains a top priority within the Imp
201 ual epidemics of virus-induced encephalitis, hemorrhagic fever\shock syndromes, and arthritis, respec
203 Ebola virus disease (EVD), a severe viral hemorrhagic fever syndrome caused by Ebola virus (EBOV)
206 s (e.g., Lassa and Junin) which cause severe hemorrhagic fever syndromes with high mortality rates.
207 onging to the family Filoviridae that causes hemorrhagic fever syndromes with high-mortality rates.
208 In its most severe form, YF manifests as a hemorrhagic fever that causes severe damage to visceral
209 ers of the Filoviridae family, causes severe hemorrhagic fever that is highly lethal, with up to 90%
210 er (RVF) is an emerging, zoonotic, arboviral hemorrhagic fever threatening livestock and humans mainl
211 ilitate the occurrence of more-severe dengue hemorrhagic fever through immune enhancement upon infect
212 data from non-human primate models of viral hemorrhagic fever to better understand the host transcri
218 he viral life cycle.IMPORTANCE Crimean-Congo hemorrhagic fever virus (CCHFV) is a priority pathogen t
233 uses including TBEV, Louping ill virus, Omsk hemorrhagic fever virus (OHFV), Alkhurma virus (ALKV), K
237 infected crab-eating macaques, while simian hemorrhagic fever virus (SHFV) causes lethal viral hemor
239 then crab-eating macaques with either simian hemorrhagic fever virus (SHFV) or Kibale red colobus vir
245 responses in control of acute Crimean-Congo hemorrhagic fever virus infection is largely unclear.
247 or zoonotic pathogens, such as Crimean Congo hemorrhagic fever virus, Babesia, Theileria, and Anaplas
248 of vOTUs originating from the Crimean-Congo hemorrhagic fever virus, Erve virus, and Nairobi sheep d
249 relatives of these viruses, including simian hemorrhagic fever virus, have caused sporadic outbreaks
250 member of the same subtype as Crimean-Congo hemorrhagic fever virus, responsible for fatal human dis
252 virales and closely related to Crimean-Congo hemorrhagic fever virus, which is responsible for severe
254 ic health importance, such as the category A hemorrhagic fever viruses Lassa virus, Junin virus, Mach
255 (LASV), two unrelated but highly pathogenic hemorrhagic fever viruses that have caused outbreaks in
256 esponding to the challenges of confronting 2 hemorrhagic fever viruses will require continued investm
262 face.IMPORTANCE Although outbreaks of Korean hemorrhagic fever were first recognized during the Korea
264 bocytopenia is a common finding during viral hemorrhagic fever, which includes hemorrhagic fever with
265 oved vaccines and/or treatments for Bolivian hemorrhagic fever, which is a fatal human disease caused
266 one of several viruses that can cause viral hemorrhagic fever, which is characterized by uncontrolle
267 ortant human pathogen responsible for dengue hemorrhagic fever, whose global incidence has increased
268 the causative agent of Lassa fever, a viral hemorrhagic fever with a case fatality rate of approxima
270 of the genus Ebolavirus, result in a severe hemorrhagic fever with a fatal outcome in over 50% of hu
272 is an ambisense RNA virus that causes severe hemorrhagic fever with a high fatality rate in humans in
276 s a tick-borne Nairovirus that causes severe hemorrhagic fever with a mortality rate of up to 30% in
277 dent hosts but can lead to severe and lethal hemorrhagic fever with bleeding and multiorgan failure i
278 o includes Ebola virus (EBOV), causes lethal hemorrhagic fever with case fatality rates that have exc
280 virus (EBOV) is an RNA virus that can cause hemorrhagic fever with high fatality rates, and there ar
281 Ebolavirus and Marburgvirus cause severe hemorrhagic fever with high mortality and are potential
285 humans, where they provoke diseases such as Hemorrhagic fever with Renal Syndrome (HFRS) and its mil
286 ct mammals, including humans, causing either hemorrhagic fever with renal syndrome (HFRS) or hantavir
291 In humans, orthohantavirus infection causes hemorrhagic fever with renal syndrome or hantavirus card
298 dae family and can cause outbreaks of severe hemorrhagic fever, with high mortality rates in humans.
299 irus, a cousin of Ebola virus, causes severe hemorrhagic fever, with up to 90% lethality seen in rece
300 (EBOV) and related filoviruses cause severe hemorrhagic fever, with up to 90% lethality, and no trea