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1 esters as determined in incubations with rat hepatic microsomes.
2 d 6-hydroxy-2-nitropyrene from 2-NP in human hepatic microsomes.
3 mers were more metabolically stable in human hepatic microsomes.
5 nal properties observed previously in intact hepatic microsomes and displayed the highest specific ac
8 y the same metabolites as produced by murine hepatic microsomes, but the 2-min metabolite was the maj
9 L1 preadipocyte cells, TBMEHP inhibited rat hepatic microsome deiodinase activity and was an agonist
10 effect on CCl4-induced lipid peroxidation of hepatic microsomes, exceeds that produced by alpha-tocop
11 asured by LC-MS/MS methods.CYP3A activity in hepatic microsomes exhibited a significant decrease in M
13 reaction for CYP3A4) was reduced by >50% in hepatic microsomes from CYP3A4-HBN mice compared with co
14 tro glucuronidation of SN-38 was screened in hepatic microsomes from normal rats (n = 4), normal huma
16 e formation of the HMM bands was observed in hepatic microsomes isolated from rats treated 1 week or
19 ected in rat, hamster, dog, monkey, or human hepatic microsomes, suggesting the lack of oral toxicity
20 of retinol metabolism have been described in hepatic microsomes that involve, in part, cytochrome P45
21 shown to be specific in human plasma and rat hepatic microsomes, was further combined with the SRM tr
23 on and butanol extraction, we found that all hepatic microsomes were competent to activate 3-NBA.
26 reduced accumulation in small intestinal and hepatic microsomes, which influenced the rate of ezetimi
28 sized sEH inhibitors were extracted from rat hepatic microsomes with ethyl acetate and were determine