ライフサイエンスコーパス: heterocyclic

1 ltered complex I inhibition, identifying the heterocyclic 1,3-nitrogen motif as the toxicophore.

2 fy a class of small-molecule iHAPs (improved heterocyclic activators of PP2A) that kill leukemia cell

3 Two synthetic approaches to the key heterocyclic aglycon 7, (i) a six-step classical heteroc

4 The formed 2-heterocyclic-alcohols are valuable building blocks in dr

5 ubstituted diamines and substituted aromatic/heterocyclic/aliphatic aldehydes under aerial conditions

6 An efficient cycloaddition of heterocyclic alkenes with nitrile oxides generated in si

7 es on the controlled generation of transient heterocyclic alkynes and arynes.

8 haps due to generation during cooking [e.g., heterocyclic amine (HCA) intake].

9 iral cis-2-alkyl-substituted carbocyclic and heterocyclic amine derivatives in excellent enantiomeric

10 ring systems starting from widely available heterocyclic amine nucleophiles and carbonyl electrophil

11 MCC was studied concerning the formation of heterocyclic amines (HAAs).

12 Inhibitors include heterocyclic amines (tricyclic antidepressants) and 21 n

13 Diverse protonation of the heterocyclic amines and oxime groups of the bis-oximes r

14 kylation of diverse aromatic carbocyclic and heterocyclic amines directly with carboxylic acids, by-p

15 relationships between Maillard products and heterocyclic amines formation, as well as between volati

16 rocess will expedite the syntheses of chiral heterocyclic amines of significance to chemistry, biolog

17 any natural products and medicinal drugs are heterocyclic amines possessing a chiral quaternary carbo

18 f N-hydroxylated metabolites of aromatic and heterocyclic amines.

19 for the synthesis of phenanthrenes and their heterocyclic analogues (Mallory reaction).

20 le N-(2-furylethyl)-2-nitroanilines or their heterocyclic analogues followed by the reductive cycliza

21 nthesis of a library of various aromatic and heterocyclic analogues of naturally occurring homoisofla

22 ionalized and structurally diverse benzylic, heterocyclic and aliphatic primary, secondary and tertia

23 ousing medicinally relevant halogen, oxygen, heterocyclic and biaryl moieties.

24 and (iii) development of SOA parameters for heterocyclic and oxygenated aromatic compounds based on

25 reaction of p-quinone with range of cyclic, heterocyclic, and acyclc dienes and also the reaction of

26 s been developed for building seven-membered heterocyclic architectures.

27 This method features a broad scope of both heterocyclic arenes (pyridine, quinoline, pyrazole, imid

28 re substrates a steep increase in associated heterocyclic aroma compound production was noted at proc

29 ted in order to clarify the formation of the heterocyclic aromatic amine (HAA) 2-amino-3,4-dimethylim

30 hoice of antioxidants to reduce carcinogenic heterocyclic aromatic amine (HAA) formation during prote

31 and sensory pork quality on the formation of heterocyclic aromatic amines (HAAs) after heat treatment

32 Heterocyclic aromatic amines (HAAs) are defined as a maj

33 Heterocyclic aromatic amines (HAAs) are neo-formed compo

34 cinal plant Asclepias subulata (ASE) against heterocyclic aromatic amines (HAAs) commonly found in co

35 Among them, the formation of heterocyclic aromatic amines (HAAs) has been related to

36 eIQx and is valid for the formation of other heterocyclic aromatic amines (HAAs) with the structure o

37 The list of heterocyclic aromatics and the mass spectral library gen

38 Although the signals of these heterocyclic aromatics diminished with distance, some we

39 from the analysis, focusing mainly on other heterocyclic aromatics.

40 uction of rotationally restricted, nonplanar heterocyclic arrays with discrete sizes and molecular sh

41 rapid access to a diverse array of different heterocyclic as well as carbocyclic products.

42 n enhancement in the rate or efficiency of a heterocyclic azadiene cycloaddition by hydrogen bonding

43 nt and use of the cycloaddition reactions of heterocyclic azadienes (1,2,4,5-tetrazines; 1,2,4-, 1,3,

44 hydrazones, quinolylimines, QNs, and related heterocyclic azolylnitrones.

45 method for the synthesis of fused bioactive heterocyclic backbones containing quinoline, pyrrolidone

46 a C-C rather than a C-N linkage between the heterocyclic base and the ribofuranose ring.

47 aturated moieties embedded within linear and heterocyclic biologically active entities can be obtaine

48 ed here is a new type of strongly donating N-heterocyclic boryloxy (NHBO) ligand, [(HCDippN)(2) BO](-

49 2H-Azirine-2-carbonyl azides, new reactive heterocyclic building blocks, were synthesized in high y

50 thesis of beta-benzyl-substituted 5-membered heterocyclic carbaldehydes via transient directing-group

51 transfer processes involving the iron(III) N-heterocyclic carbene (FeNHC) photosensitizer [Fe(phtmeim

52 on in the use of gold(i) complexes bearing N-heterocyclic carbene (NHC) and phosphine (PR(3)) ligands

53 radical coupling was made possible merging N-heterocyclic carbene (NHC) and photoredox catalysis.

54 ies of neutral molybdenum imido alkylidene N-heterocyclic carbene (NHC) bistriflate and monotriflate

55 n of aza-o-quinone methides (aza-o-QMs) by N-heterocyclic carbene (NHC) catalysis has been discovered

56 lkali-metal-mediated metalation (AMMM) and N-heterocyclic carbene (NHC) chemistry, a novel C-N bond a

57 Iron N-heterocyclic carbene (NHC) complexes have received a gre

58 Radical H atom abstraction from a set of N-heterocyclic carbene (NHC) complexes of alkenylboranes b

59 A series of palladium N-heterocyclic carbene (NHC) complexes of type trans-{(NHC

60 The remarkable resilience of N-heterocyclic carbene (NHC) gold bonds has quickly made N

61 Although N-heterocyclic carbene (NHC) iridium complexes are promisi

62 ve been prepared, where :C^N is a helicene-N-heterocyclic carbene (NHC) ligand and X=Cl or I.

63 he use of a complex bearing an unsaturated N-heterocyclic carbene (NHC) ligand, for the first time, p

64 nium catalysts with varying sterics of the N-heterocyclic carbene (NHC) ligand.

65 It is well-recognized that N-heterocyclic carbene (NHC) ligands have provided a new d

66 complexes bearing C(1)- and C(2)-symmetric N-heterocyclic carbene (NHC) ligands were prepared from pr

67 lometalated ruthenium catalysts with bulky N-heterocyclic carbene (NHC) ligands.

68 lized cationic molybdenum imido alkylidene N-heterocyclic carbene (NHC) monotriflate complex with 2-m

69 metrical unsaturated 2,6-diisopropylphenyl N-heterocyclic carbene (NHC) precursors with excellent sel

70 AAC) catalysts relative to their important N-heterocyclic carbene (NHC) predecessors, as recently dem

71 revealed that the reaction proceeds via an N-heterocyclic carbene (NHC) siloxygermylene [(NHC)RGe(OSi

72 A fused pi-helical N-heterocyclic carbene (NHC) system was prepared and exami

73 rmediate resulting from the addition of an N-heterocyclic carbene (NHC) to benzaldehyde triggers a fa

74 e relative trans effect of picoline vs the N-heterocyclic carbene (NHC) was quantified through a kine

75 N-Heterocyclic carbene (NHC)- and cyclic (alkyl)(amino)car

76 ron-centered radicals derived from alkenyl N-heterocyclic carbene (NHC)-boranes bearing ester substit

77 f readily available alkenyl triflates with N-heterocyclic carbene (NHC)-boranes in the presence of di

78 N-Heterocyclic carbene (NHC)-catalyzed intramolecular aldo

79 An N-heterocyclic carbene (NHC)-catalyzed intramolecular Stet

80 The reductive coupling of a N-heterocyclic carbene (NHC)-stabilized aryldibromoborane

81 ordinated to two N-(2-pyridyl)-substituted N-heterocyclic carbene (PyNHC) ligands in a bidentate fash

82 Specifically, N-heterocyclic carbene 1,3-bis(2,6-diisopropylphenyl)imida

83 nt comprehensively and covers the usage of N-heterocyclic carbene adducts of the p-block elements as

84 nes upon thermolysis in the presence of an N-heterocyclic carbene borane (NHC-borane) and di-tert-but

85 nzo[3,4]cycloundec-3-ene-1,5-diyne with an N-heterocyclic carbene borane.

86 Reactions of N-heterocyclic carbene boranes (NHC-boranes) with electron

87 ing materials is developed using oxidative N-heterocyclic carbene catalysis.

88 Copper N-heterocyclic carbene complexes serve as mediators for th

89 pyridine as catalyzed by Ni/AlMe(3) and a N-heterocyclic carbene ligand has recently been establishe

90 al control to locate the strongly donating N-heterocyclic carbene ligand trans to the site of CO(2) a

91 l complexes were synthesized with the tris-N-heterocyclic carbene ligand tris[2-(3-mesitylimidazol-2-

92 er-based complex that contains a sulfonate N-heterocyclic carbene ligand was first reported 15 years

93 resulting in chelating pyridylidene remote N-heterocyclic carbene ligands (rNHCs).

94 Two N-heterocyclic carbene ligands provide orthogonal chemosel

95 in the study of gold complexes containing N-heterocyclic carbene ligands with biological properties.

96 were investigated bearing nonconventional N-heterocyclic carbene ligands, monoamido-aminocarbene (MA

97 design of a novel, redox-active bipyridyl- N-heterocyclic carbene macrocyclic ligand complexed with n

98 (Dep), or 2,6-diisopropylphenyl (Dip); D = N-heterocyclic carbene or 4-dimethylaminopyridine, DMAP),

99 ociation of a mechanophore built around an N-heterocyclic carbene precursor proceeds with the rupture

100 rationally designed redox-active Au(I) bis-N-heterocyclic carbene that induces ICD both in vitro and

101 The reaction of N-heterocyclic carbene with N-tBu-substituted pyrrolinium

102 on of the acyclic amido-chlorosilylene bis(N-heterocyclic carbene) Ni(0) complex [{N(Dipp)(SiMe3 )ClS

103 u(I)(NHC) (bdt = benzene dithiolate, NHC = N-heterocyclic carbene) sites.

104 he germylone dimNHCGe (5, dimNHC = diimino N-heterocyclic carbene) was successfully prepared via the

105 (NHC(R)=N)(2)(CH(3))P, where NHC(R) is an N-heterocyclic carbene).

106 us cyclic enal-enones were reacted with an N-heterocyclic carbene, and an intramolecular Stetter reac

107 complex with a chiral sulfonate-containing N-heterocyclic carbene, are broadly applicable.

108 ) was achieved by taking advantage of NHC (N-heterocyclic carbene, here IDipp) coordination to the lo

109 to the conclusion that other phosphine and N-heterocyclic carbene, such as P (n)BuAd(2) and IMes, can

110 These substrates were then exposed to an N-heterocyclic carbene, whereupon intramolecular Stetter r

111 ormed through one-electron oxidation of an N-heterocyclic carbene-carbodiimide (NHC-CDI) zwitterionic

112 s been synthesized from the combination of N-heterocyclic carbene-ligated gold(I) trimethylsilylchalc

113 Au(I)-catalyzed Conia ene reaction and an N-heterocyclic carbene-mediated acyloin addition to rapidl

114 st ligated by a highly sterically hindered N-heterocyclic carbene.

115 pp=2,6-Pr(i)2 C6 H4 ) and two NHC ligands (N-heterocyclic carbene=:C[(Pr(i) )NC(Me)]2 ) was synthesiz

116 -->Ni(NHC)2 ] (1; Dipp=2,6-(i) Pr2 C6 H4 ; N-heterocyclic carbene=C[((i) Pr)NC(Me)]2 ) with N2 O furn

117 2) for 4; Dipp = 2,6-iPr(2)C(6)H(3); NHC = N-heterocyclic carbene] as red crystalline solids containi

118 An N-heterocyclic-carbene-ligated 3-benzoborepin with a bridg

119 We report the use of two polymeric N-heterocyclic carbenes (NHC) (polydentate and monodentate

120 N-Heterocyclic carbenes (NHC) are nowadays ubiquitous and

121 ne complexes from readily available chiral N-heterocyclic carbenes (NHCs) and chiral diamines is disc

122 The use of N-heterocyclic carbenes (NHCs) as ancillary ligands has ma

123 N-Heterocyclic carbenes (NHCs) catalyzing aza-Claisen rear

124 carboquinoid and stabilized by two capping N-heterocyclic carbenes (NHCs) has been prepared.

125 itable ligands such as bulky phosphines or N-heterocyclic carbenes (NHCs) has enabled reactions of un

126 ent density functional theory computations.N-heterocyclic carbenes (NHCs) have been applied as ancill

127 Although N-heterocyclic carbenes (NHCs) have been known as ligands

128 N-heterocyclic carbenes (NHCs) have been widely utilized f

129 Although N-heterocyclic carbenes (NHCs) have demonstrated outstandi

130 strongly coordinating dianionic carboranyl N-heterocyclic carbenes (NHCs) to create organometallic -a

131 N-Heterocyclic carbenes (NHCs) were recently shown to form

132 ent advancement in functionalizing gold by N-heterocyclic carbenes (NHCs), a promising alternative li

133 dimethyl-4,5-disubstituted imidazolylidene N-heterocyclic carbenes (NHCs), where the 4,5-substituents

134 nd imidazolidin-2-ylidenes, the well-known N-heterocyclic carbenes (NHCs).

135 rene (9,10-diboraanthracene) stabilized by N-heterocyclic carbenes and its one- and two-electron oxid

136 The emergence of N-heterocyclic carbenes as ligands across the Periodic Tab

137 Mechanistic aspects of the N-heterocyclic carbenes catalyzed aerobic oxidation of ald

138 ruthenium metathesis catalyst bearing two N-heterocyclic carbenes with an oxidizing pyrylium photoca

139 n affinity rival those of ylide-stabilized N-heterocyclic carbenes.

140 and similar to that observed in classical N-heterocyclic carbenes.

141 orizontal lineAl double bond stabilized by N-heterocyclic carbenes.

142 ation of asymmetric redox-active Au(I) bis-N-heterocyclic carbenes.

143 the antipsychotic drug aripiprazole and the heterocyclic catecholamine surrogates present in the bet

144 ed a variety of compounds belonging to three heterocyclic chemical series: imidazo[1,2-a]pyrazine, im

145 lding blocks for cross-coupling reactions or heterocyclic chemistry.

146 lkylating agents is a fundamental problem in heterocyclic chemistry.

147 of this remarkable chemist and his legacy to heterocyclic chemistry.

148 ethers enables storage of otherwise unstable heterocyclic chlorides and limits costly decomposition.

149 Suzuki/S(N)Ar processes inaccessible to the heterocyclic chlorides.

150 -C bond activation to give the unusual spiro-heterocyclic compound (5).

151 bonyl compounds, polyhydroxyalkyl pyrazines, heterocyclic compound and alkylimidazoles.

152 The potentially toxic heterocyclic compound, 5-hydroxymethylfurfural (HMF) was

153 s were tentatively identified as nitrogenous heterocyclic compounds (e.g., 3-chloro-5-hydroxy-1H-pyrr

154 re an important class of biologically active heterocyclic compounds and potential drug candidates.

155 ort the first synthesis of a family of novel heterocyclic compounds based on a 5-dihydropyrazolo[3',4

156 -light mediated aerobic dehydrogenation of N-heterocyclic compounds is a reaction with enormous poten

157 soquinolines for the construction of complex heterocyclic compounds is also demonstrated.

158 nally functionalized alkyl, carbocyclic, and heterocyclic compounds is described.

159 Despite abundant emissions, heterocyclic compounds that included furans contribute t

160 This work reports the preparation of complex heterocyclic compounds using direct metalation of thioph

161 tro, halo, alkoxy, thiomethoxy, and S- and N-heterocyclic compounds) that can be scaled up.

162 ounds such as other cycloalkane derivatives, heterocyclic compounds, stereodefined 1,3-dienes, and li

163 efficiently transformed into a rare class of heterocyclic compounds-dibenzo[b,f][1,5]diazocines-by a

164 as ergot, hapalindole alkaloids, and related heterocyclic compounds.

165 ccess to a variety of underexplored strained heterocyclic compounds.

166 nditions for easy access of various arylated heterocyclic compounds.

167 as the position of the nitrogen atoms in the heterocyclic core determined to a large extent the bindi

168 cture-activity relationship (SAR) studies of heterocyclic core modifications to replace the imidazole

169 The SuFExable library comprises 10 discrete heterocyclic core structures derived from 1,3- and 1,5-d

170 were attached to the same central, saturated heterocyclic core.

171 Nonetheless, simple catalytic routes to new heterocyclic cores are infrequently reported, and method

172 f 200) affords targeted C-H hydroxylation on heterocyclic cores, while preserving electron-neutral an

173 onic acid derivatives and is compatible with heterocyclic coupling partners.

174 iological evaluation of a series of 17 novel heterocyclic derivatives of isocombretastatin-A4 (iso-CA

175 species, strained cyclic allenes, especially heterocyclic derivatives, have only recently resurfaced

176 e of 2-aryl-1,3-dithianes, including several heterocyclic derivatives, react with [1.1.1]propellane t

177 These small molecules of the heterocyclic diamidine family disrupted the interaction

178 base pairs, we recently discovered that the heterocyclic diamidine, DB2277, forms a strong monomer c

179 ing the DNA binding, we selected a series of heterocyclic diamidines as efficient competitors for the

180 tic research of unprecedented multitargeting heterocyclic ferrociphenols bearing either a succinimidy

181 her to ultimately give rise to the desired N-heterocyclic four-membered ring.

182 d vinyl electrophiles and is compatible with heterocyclic fragments in both coupling partners.

183 the chemistry of macrocyclic peptides having heterocyclic fragments in their structure.

184 A new fused N-heterocyclic framework, dipyrazolo-1,3,5-triazinane, was

185 lates, which contain 18 different pentagonal heterocyclic frameworks at position 4, was synthesized a

186 lticomponent fashion often result in complex heterocyclic frameworks, which have attracted the attent

187 Me with alkyl bromides for the decoration of heterocyclic frameworks.

188 arylation under mild conditions to give new heterocyclic frameworks.

189 rasubstituted pyridines including carbo- and heterocyclic fused ones.

190 oxazolo[3,4-b]quinolin-3(1H)-one as "masked" heterocyclic hydroxylamines to generate Paal-Knorr inter

191 which is isoelectronic with the well-known N-heterocyclic iminato (NHI) donor class.

192 the direct reaction of the lithium salt of N-heterocyclic imine (NHI) with phenylchloro-2,6-diisoprop

193 C-O bond, and two rings (one carbo- and one heterocyclic) in a single operation.

194 Peptidomimetic vinyl heterocyclic inhibitors (PVHIs) containing Cbz-Phe-Phe/h

195 ive catalysts in the asymmetric reduction of heterocyclic ketones (S/C = 100-500, ee up to 99%).

196 This strategy leads to fused heterocyclic lactone scaffolds in a single step with mod

197 tudy the influence of the acidity (pK(a)) of heterocyclic leaving group of triazole urea derivatives

198 ing different appendages including different heterocyclic moieties were realized through this rapid a

199 erates a wide range of functional groups and heterocyclic moieties, efficiently providing useful cyan

200 Compounds that consisted of one aromatic heterocyclic moiety (azoxystrobin, fluazifop acid, fluaz

201 f C3-substituted imidazo[1,2-a]pyridines, an heterocyclic moiety commonly found in medicinal chemistr

202 alkyl substituents for introduction into the heterocyclic moiety, and uses convenient transformations

203 ade; and (iv) the tether forms an additional heterocyclic moiety, imidazolidine-4,5-dione, a known ph

204 highly functionalized 6-membered carbo- and heterocyclic molecules in a single step with high effici

205 yrazoles as well as other pyrazole-based bis-heterocyclic molecules were prepared in moderate to high

206 oproteins, synthetic lipopeptides, and small heterocyclic molecules.

207 y the ring-opening polymerization of various heterocyclic monomers such as lactones, carbonates, or e

208 y to construct large arrays of spirooxindole heterocyclic motifs.

209 table for a preponderance of highly valuable heterocyclic motifs.

210 became much more oxidized and enriched with heterocyclic N-containing compounds.

211 erties of Mn(III)-OOR complexes containing N-heterocyclic (N(Ar)) ligand scaffolds can have a dramati

212 tended, polycyclic heteroaromatic molecules (heterocyclic nanographenes) are a highly versatile class

213 expected thionated NDI derivatives 2-6, new heterocyclic naphtho-p-quinodimethane compounds 7 depict

214 Accordingly, the inclusion of heme-binding heterocyclic nitrogen moieties in P450 17A1 inhibitors m

215 pyrazines, furans, ketones, organic acid and heterocyclic nitrogen-containing compounds (p < 0.05).

216 al dye indigo led to desymmetrization of the heterocyclic nucleus via a Grignard addition-dehydration

217 The mechanism here proposed involves an N-heterocyclic olefin (NHO) catalytic species that acts as

218 The reaction of nitrous oxide (N(2)O) with N-heterocyclic olefins (NHOs) results in cleavage of the N

219 erocycles with an exocyclic double bond (= N-heterocyclic olefins, NHOs) has been determined using DF

220 tanes, cyclobutenes, and their corresponding heterocyclic or heterosubstituted analogs.

221 entify and explore the potential of nitrogen heterocyclic PACs (NPACs) as source indicators in snowpa

222 We designed a set of heterocyclic phosphines that are installed at the 4-posi

223 Azaarenes are N-heterocyclic polyaromatic pollutants that co-occur with

224 isking approach toward the radiosynthesis of heterocyclic positron emission tomography (PET) radiolig

225 A seven-membered N,N'-heterocyclic potassium alumanyl nucleophile is introduce

226 Interestingly, some of these N-heterocyclic products possess the tricyclic core of epim

227 ntramolecular C-H bond amination to afford N-heterocyclic products using aliphatic azide substrates.

228 a highly modular entry to a range of useful heterocyclic products with excellent selectivity and fun

229 igmatropic rearrangement to directly furnish heterocyclic products with net retention at the new C-C

230 earrangements to deliver the fused and spiro-heterocyclic products.

231 are the first metallacycles bearing nitrogen heterocyclic radicals as bridges.

232 udies demonstrate stereoelectronic tuning of heterocyclic ring pucker, cis/trans amide propensity, an

233 itution reaction in a biologically important heterocyclic ring system.

234 We found four of these adducts involved the heterocyclic ring, similar to the reaction with other py

235 ion of BN-[10]CPP selectively reduces the BN heterocyclic ring, which upon hydrolysis produces a rare

236 of an internal H-bond to replace a saturated heterocyclic ring.

237 ing a chiral quaternary carbon atom in their heterocyclic ring.

238 and 3 C-N or 1 C-C, 1 C-O and 2 C-N) and two heterocyclic rings in a single operation.

239 Several examples of bis-heterocyclic rings were also synthesized through the pro

240 obacterial biotin synthesis, assembly of the heterocyclic rings, are thought to follow the canonical

241 , as well as hydroxylation of photo-oxidized heterocyclic rings, have been identified during photodeg

242 id pimelate moiety and assembly of the fused heterocyclic rings.

243 route toward the synthesis of a plethora of heterocyclic rings.

244 its structure, the 5-membered chiral biaryl heterocyclic scaffold represents a departure from 6-memb

245 agment-based approach, we discovered a small heterocyclic scaffold that binds proximal to the Gna1 ac

246 olidone-ring annulated thiophene/furan-based heterocyclic scaffolds (e.g., 4,5-dihydro-6H-thieno[2,3-

247 rd methodology to access bicyclic carbo- and heterocyclic scaffolds combining different ring sizes th

248 utes toward synthesis of nitrogen-containing heterocyclic scaffolds has inspired organic chemists to

249 e preparation of a wide range of benzo-fused heterocyclic scaffolds using iron and copper catalysis i

250 ross-dehydrogenative coupling of biorelevant heterocyclic scaffolds with arylmethanes for aroylation

251 d with a wide array of medicinally important heterocyclic scaffolds with diverse functional group tol

252 multisubstituted seven-membered nitrogenous heterocyclic scaffolds, an efficient method, employing 2

253 cyclobutene amine derivatives give fused aza-heterocyclic scaffolds.

254 s, alkynes, and arenes) into the sp(3) -rich heterocyclic scaffolds.

255 mployed in strategies for developing diverse heterocyclic scaffolds.

256 e versatile precursors for various bioactive heterocyclic scaffolds.

257 -C(sp(2)) bond in order to prepare novel bis-heterocyclic scaffolds.

258 ine)-based block copolymer with the aromatic heterocyclic side chains in one block, poly(2-methyl-2-o

259 e)CN(i-Pr)}(2)CH](+)(2)[S(6)](2-) (4), and N-heterocyclic silylene 5, unexpectedly results in synergi

260 orresponding reaction with the unsaturated N-heterocyclic silylene c-(CH)(2) (NtBu)(2) Si: proceeds d

261 The first bis(N-heterocyclic silylene)-stabilized zero-valent silicon co

262 i(II)]Ge(0), stabilized by a chelating bis(N-heterocyclic silylene)xanthene donor ligand 1 was succes

263 4) (Tip=2,4,6-triisopropylphenyl) with the N-heterocyclic silylenes c-[(CR(2) CH(2) )(NtBu)(2) ]Si: (

264 Starting from the 1,2-bis(N-heterocyclic silylenyl) 1,2-dicarba-closo-dedocaborane(1

265 r triazole-NHC control to give unknown fused heterocyclic skeletons, pyrrolo[3,2-c][1,2,4]triazolo[5,

266 1H-imidazo[2,1-a]pyrrolo[3,4-c]isoquinoline heterocyclic skeletons, which were further transformed i

267 f a chemical library, we identified a set of heterocyclic small molecules as potential inhibitors of

268 well developed approaches for the design of heterocyclic solid-state organic ionic conductors (SOICs

269 Three rigid and structurally simple heterocyclic stilbene derivatives, (E)-3H,3'H-[1,1'-biis

270 These studies underscore how the use of heterocyclic strained intermediates can be harnessed for

271 Methods that provide rapid access to new heterocyclic structures in biologically relevant chemica

272 ows access to a diverse range of interesting heterocyclic structures.

273 N and PyOM, more than 10% of which contained heterocyclic structures.

274 access to a wide range of previously unknown heterocyclic structures.

275 benzylic oxidation of heteroarenes to afford heterocyclic styrenes by the action of nickel catalysis

276 rylisoxazoles, bearing unsaturated carbo and heterocyclic substituents at the position 4, gives the c

277 organosilanes with alkyl, aryl, alknyl, and heterocyclic substituents were tolerated, as well as ste

278 However, carbene transferases accepting heterocyclic substrates are scarce; the few enzymes capa

279 suggests that the oxidative sulfurization of heterocyclic substrates may occur in a broad range of ba

280 s and can be applied to both carbocyclic and heterocyclic substrates.

281 Pyridine and related heterocyclic sulfinates have recently emerged as effecti

282 A series of acidic diaryl ether heterocyclic sulfonamides that are potent and subtype se

283 he photophysical properties of the resulting heterocyclic sulfonimidamide derivatives were characteri

284 An efficient three-step synthesis of a new heterocyclic system is described wherein the 2H-bis([1,2

285 be expected for a series of nucleobases and heterocyclic systems in general.

286 r the synthesis of three-dimensional, chiral heterocyclic systems, important synthetic building block

287 ium salts, in an effort to form a variety of heterocyclic systems, namely, 3-amino(benzo)thiophenes,

288 at C3 makes it possible to construct two new heterocyclic systems, namely, a benzimidazolone and a py

289 d [3,4-a]isoquinolines, as well two more new heterocyclic systems, pyrrolo[3,4-c][1,2,4]triazolo[5,1-

290 a valuable method for the formation of fused heterocyclic systems.

291 aborininones with the analogous carbon-based heterocyclic systems.

292 ynthetic approach for preparing a variety of heterocyclic tetrahydropentacene derivatives via nucleop

293 c hydrogenation of aliphatic carbocyclic and heterocyclic tetrasubstituted enamides, to generate a se

294 The direct amination reaction of heterocyclic thiols has been developed in the presence o

295 inazoline derivatives from the corresponding heterocyclic thiols with amines in good to excellent yie

296 ed through participation of various aryl and heterocyclic thiols.

297 he preparation of 3-, 4-, 5-, and 6-membered heterocyclic unnatural amino acid derivatives by exploit

298 (SAR) in the aurone pharmacophore identified heterocyclic variants of the (Z)-2-benzylidene-6-hydroxy

299 crystalline solids containing a pai-donor N-heterocyclic vinyl (NHV) substituent at the phosphorus a

300 These new reactive and selective heterocyclic warheads supplement the current repertoire