ライフサイエンスコーパス: heterodimeric

1 SFTI-1 (sunflower trypsin inhibitor-1) and a heterodimeric 2S albumin.

2 TmrAB is a heterodimeric ABC exporter from the thermophilic Gram-ne

3 Here, we present the apo structure of the heterodimeric ABC exporter TM287/288 and compare it to t

4 k, we capture substrate translocation in the heterodimeric ABC exporter TM287/288 from the hypertherm

5 DEER measurements on the heterodimeric ABC exporter TM287/288 from Thermotoga mar

6 d with antigen processing (TAP) is a 150 kDa heterodimeric ABC transport complex that selects peptide

7 uantitative mechanistic understanding of the heterodimeric ABC transporter TmrAB, a functional homolo

8 Here we report that, for the heterodimeric ABC transporter TmrAB, the extent of delip

9 aneic acids A and B are formally dimeric and heterodimeric adducts of yunnaneic acids C and D.

10 le linker was removed, yielding fully mature heterodimeric albumin.

11 Integrins are heterodimeric alpha/beta extracellular matrix adhesion r

12 7R)- and (2S,7S)-2 and a series of homo- and heterodimeric analogues in which octanedioic acid was us

13 ution cryo-EM data is superior in predicting heterodimeric and heterotrimeric protein assemblies.

14 e sought crystal structures of aglycosylated heterodimeric and homodimeric "knob" and "hole" Fc fragm

15 esent cryo-electron microscopy structures of heterodimeric and homodimeric full-length GABA(B) recept

16 r structural and functional differences, the heterodimeric and homodimeric kinesin-14s share a common

17 nsing, it is unknown why the Rag GTPases are heterodimeric and whether their subunits communicate wit

18 e describe the identification of a series of heterodimeric antagonists with highly potent antiprolife

19 X-ray structures of the heterodimeric ApeO:ApeC and ApeI:ApeP complexes depict s

20 The structure reveals the heterodimeric architecture of the complex and donor subs

21 , a potential drug target, is unique for its heterodimeric arrangement and an active site different f

22 Although recent studies have suggested heterodimeric assembly of mGlu receptors in vitro, the d

23 signaling can be silenced through a physical heterodimeric association with CB2, thereby inhibiting s

24 binding and transcriptional activity through heterodimeric association with several members of the nu

25 The carotenoid is required for the heterodimeric association, assembling an orange complex

26 Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprise

27 intenance of chromosomes 1 and 3 (Smc1-Smc3) heterodimeric ATPase, the kleisin subunit sister chromat

28 of proteins that bind the TIRs identified a heterodimeric basic leucine zipper (bZIP) complex betwee

29 nuclear egress-regulating proteins forming a heterodimeric basic structure of the nuclear egress comp

30 Here, we report on a heterodimeric beta-etherase (BaeAB) from the sphingomona

31 y reported efficient heavy-chain assembly of heterodimeric bispecific antibodies by exchanging the in

32 e developed a novel one-arm single chain Fab heterodimeric bispecific IgG (OAscFab-IgG) antibody form

33 n by homodimeric BMP2, homodimeric BMP6, and heterodimeric BMP2/6 were blunted in Hfe KO primary hepa

34 found that ATF4 forms at least five distinct heterodimeric bZIP transcription factors in skeletal mus

35 Each of these actin structures relies on heterodimeric capping protein (CAPZ), which blocks actin

36 xperimental system to modulate the levels of heterodimeric capping protein (CP) and examine the conse

37 Heterodimeric capping protein (CP) binds the rapidly gro

38 Heterodimeric capping protein (CP) is a conserved and ub

39 s accompanied by abnormal Arp2/3 complex and heterodimeric capping protein accumulation.

40 ted differently in transduction mutants; the heterodimeric capping protein subunit CAPZB and its part

41 r genetic studies reveal that the ubiquitous heterodimeric capping protein transduces ROS signaling t

42 Moreover, Twf2a binds heterodimeric capping proteins, but the role of this int

43 e Sox pathway are covalently attached to the heterodimeric carrier protein SoxYZ through conjugation

44 n silico studies to identify the most likely heterodimeric CCL5-HNP1 complex which was subsequently u

45 They share the heterodimeric CD122/CD132 receptor to deliver their sign

46 ic CEACAM6 complex, monomeric CEACAM8, and a heterodimeric CEACAM6-CEACAM8 complex.

47 Integrins are heterodimeric cell surface adhesion and signaling recept

48 Integrins are a large family of heterodimeric cell surface receptors that bind prototypi

49 Integrins are abundant heterodimeric cell-surface adhesion receptors essential

50 barriers and an inability to reliably infer heterodimeric chain pairings for TCRs.

51 REK-2 subunits coassemble to form functional heterodimeric channels also in native cells.

52 These screens reveal the heterodimeric, circadian rhythm TFs Clock and Bmal1 as g

53 sents an atomic resolution structure for any heterodimeric cis-PTase.

54 These data provide unique insights into how heterodimeric cis-PTases have evolved from their ancestr

55 ase catalytic subunit E9 associated with its heterodimeric co-factor A20.D4 required for processive g

56 e that CDC48A physically associates with its heterodimeric cofactor UFD1-NPL4, known to bind ubiquiti

57 e KEAP1-CUL3 E3 complex, with the aid of the heterodimeric cofactor UFD1/NPL4 and the UBA-UBX-contain

58 designed a heterotrimer from three pairs of heterodimeric coiled coils that mediate specific interac

59 ing the binding domains of antibodies with a heterodimeric coiled-coil domain that sterically occlude

60 We have substituted an antiparallel heterodimeric coiled-coil motif for the beta-strand stal

61 he retromer-linked SNX-BAR proteins comprise heterodimeric combinations of SNX1 or SNX2 with SNX5 or

62 platin analogue can specifically bind to the heterodimeric complex Atox1-Cu(I)-Mnk1 (Mnk1 is the firs

63 Here, we report the crystal structure of the heterodimeric complex between the two DIX domains of Axi

64 ly abundant of these cytochromes is a unique heterodimeric complex composed of class I and class II c

65 by a lack of structural information of this heterodimeric complex comprising an MTPalpha subunit and

66 The N-terminal acetyltransferase NatA is a heterodimeric complex consisting of a catalytic subunit

67 The Pt(II)-supported heterodimeric complex does not form if Zn(II) is used in

68 ies that bind a specific IL-4Ralpha/gamma(c) heterodimeric complex in its native signaling conformati

69 nase-like orphan receptor 2 (ROR2) to form a heterodimeric complex in mammalian cells.

70 These findings imply that such heterodimeric complex is the functional unit in mitochon

71 We determine that the heterodimeric complex of methyltransferase domains, comb

72 Activity of mtHsp70 is regulated by a heterodimeric complex of two J-domain proteins (JDPs), P

73 and auxiliary subunit (NAA25) form a stable heterodimeric complex that accepts canonical NatB-type s

74 G9a and GLP lysine methyltransferases form a heterodimeric complex that is responsible for the majori

75 In the cell, Timeless forms a constitutive heterodimeric complex with Tipin.

76 We show that METTL5 must form a heterodimeric complex with TRMT112, a known methyltransf

77 clear RNA Auxiliary Factor 1 (U2AF1) forms a heterodimeric complex with U2AF2 that is primarily respo

78 DABs accumulate bicarbonate-assemble into a heterodimeric complex, which contains a putative beta-ca

79 itin phosphorylation by wild-type PINK1 in a heterodimeric complex.

80 th the N-terminal domain of DnaA revealing a heterodimeric complex.

81 Heterodimeric complexes containing the lipase-like prote

82 ociation of G protein-coupled receptors into heterodimeric complexes has been reported for over 50 re

83 rted, and here we show that AT1R and FP form heterodimeric complexes in both HEK 293 and vascular smo

84 I domain used in TALENs to generate obligate heterodimeric complexes substantially and significantly

85 d of MCL1, but not that of BAK, forms stable heterodimeric complexes with cBID in a manner adjustable

86 members c-Jun, JunB, and JunD, which formed heterodimeric complexes with the AP-1 family members act

87 ze and provides evidence that Cullin 5 forms heterodimeric complexes with the Cullin 4a-DDB1 complex.

88 ity, we have prepared ring size variants and heterodimeric compounds, identifying the specific residu

89 othelial cells, was observed with the linked heterodimeric compounds.

90 etics of KIF3A and KIF3C motors in homo- and heterodimeric constructs and determine their transport p

91 We demonstrate that a single heterodimeric core-TAP complex is active in peptide bind

92 ase CnsC from Penicillium that catalyzes the heterodimeric coupling between two different indole moie

93 This heterodimeric cpSRP recognizes LHCP and delivers it to t

94 t/sGCbetacat model derived from the inactive heterodimeric crystal structure of the catalytic domains

95 Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 sub

96 Interleukin-27 (IL-27) is a heterodimeric cytokine composed of the subunits IL-27p28

97 (reg) cells induced Ebi3, a component of the heterodimeric cytokine IL-35 that was required for T(reg

98 eceptor, a G-protein-coupled receptor, and a heterodimeric cytokine receptor in living cells with exc

99 These tyrosine kinases associate with heterodimeric cytokine receptors such as IL-7 receptor o

100 ization of gp130, a common component of many heterodimeric cytokine receptors.

101 IL-23 and IL-12, two structurally related heterodimeric cytokines sharing a common subunit, diverg

102 in stonefish venom is stonustoxin (SNTX), a heterodimeric cytolytic protein that induces cardiovascu

103 biogenesis by promoting the formation of the heterodimeric D1/D2 reaction center complex, the site of

104 ysical properties of monomeric vs engineered heterodimeric degraders are presented.

105 d, formation of these potentially protective heterodimeric disulfide complexes is limited, and so cel

106 Sequencing of a heterodimeric dityrosine cross-linked peptide was demons

107 are exchanged in part or fully to design new heterodimeric domains.

108 Lys63-linked polyUb chains, catalyzed by the heterodimeric E2 enzyme Ube2N/Ube2V2.

109 anchored, K63-linked ubiquitin chains by the heterodimeric E2 enzyme Ube2N/Ube2V2.

110 The monoUb is a substrate for the heterodimeric E2 Ube2N/Ube2V2, resulting in TRIM21-ancho

111 the other operating with the E2 Ubc4 and the heterodimeric E3 Slx5/Slx8.

112 spiracle (USP), a component of the canonical heterodimeric ecdysone receptor, to induce malaria paras

113 1 or Arg1914 binding determinants delocalize heterodimeric envoplakin from intracellular vimentin and

114 etramerization is required for catalysis, as heterodimeric ENZ-PRO mutants lack binding affinity and

115 e palmitoyltransferase is a highly conserved heterodimeric enzyme complex.

116 is Tryptophan synthase (TrpS), an allosteric heterodimeric enzyme in the form of an alphabetabetaalph

117 ylation is believed to be catalyzed by three heterodimeric enzymes: FTase, GGTase1 and GGTase2.

118 alyses confirmed the renal expression of the heterodimeric EPO receptor/CD131 complex, which is requi

119 NA binding assays also show that, within the heterodimeric ERCC1-XPF complex, XPF specifically recogn

120 The heterodimeric eukaryotic Drs2p-Cdc50p complex is a lipid

121 Heterodimeric factor Va is produced by cleavage at three

122 ld (Bipod) comprising an scFv and a Fab on a heterodimeric Fc eliminates the possibility of light cha

123 Here, we show that the heterodimeric FLA8/10 kinesin-2 alone is responsible for

124 s support a model in which hCP exists in its heterodimeric form and is at most half-bound to Ca(2+) i

125 rmore, our data show that in higher plants a heterodimeric form of cpSRP is required for the formatio

126 a wealth of information concerning monomeric/heterodimeric forms of this kinase.

127 terestingly, the role of ABCD2 (in homo- and heterodimeric forms) in the metabolism of polyunsaturate

128 aration, a molecular feature differentiating heterodimeric from homodimeric ABC exporters.

129 GABAB receptors are heterodimeric G protein-coupled receptors, which control

130 ric acid type B (GABAB) receptors, which are heterodimeric G-protein-coupled receptors constructed fr

131 GABABRs are heterodimeric G-protein-coupled receptors that are compo

132 naling induced by nonphysiological homo- and heterodimeric GFP-mCherry ligands.

133 The heterodimeric gH/gL complex binds to the EBV epithelial

134 we show the first crystal structures of the heterodimeric GluN1-GluN2A ATD, which provide the comple

135 rum and other apicomplexans possess a unique heterodimeric glutamyl-tRNA amidotransferase consisting

136 calmodulin revealed the architecture of this heterodimeric glutamylase.

137 We show that it is a heterodimeric glyceraldehyde-3-phosphate (GAP) ferredoxi

138 The HSV heterodimeric glycoprotein gE/gI is important for antero

139 mulating hormone and luteinizing hormone are heterodimeric glycoproteins expressed in gonadotropes.

140 findings indicate that the expression of the heterodimeric gut homing integrin alpha4beta7 can influe

141 Mycobacterial AdnAB is a heterodimeric helicase-nuclease that initiates homologou

142 er understand CCC protein recruitment by the heterodimeric HIF transcription factor, we used x-ray cr

143 o-receptor enhancing the interaction between heterodimeric hIL-12 and its receptor subunits.

144 ysis and electron microscopy reveal that the heterodimeric Hop2-Mnd1 is a V-shaped molecule.

145 beta subunit proteins and, consequently, the heterodimeric hormone secretion.

146 hypoxia-response genes is controlled by the heterodimeric Hypoxia-Inducible Factor.

147 mals to hypoxia is mediated by the alphabeta-heterodimeric hypoxia-inducible transcription factors (a

148 ew strategy for making monovalent bispecific heterodimeric IgG antibodies in mammalian cells.

149 In addition, the bispecific heterodimeric IgG derived from anti-HER2 and anti-EGF re

150 The engineered heterodimeric IgG molecules maintain the overall IgG str

151 t could be embedded in monovalent bispecific heterodimeric IgG to make best-in-class therapeutic anti

152 We produced heterodimeric IgGs from transiently and stably transfect

153 nd Calu-3 human tumor models showed that the heterodimeric IgGs strongly inhibited tumor growth.

154 thus allows secretion of biologically active heterodimeric IL-12.

155 " mechanism of action for IL-15:IL-15Ralpha (heterodimeric IL-15 or hetIL-15) where the manner by whi

156 The cytokine IL-17, and signaling via its heterodimeric IL-17RA/IL-17RC receptor, is critical for

157 We found that both subunits of the heterodimeric IL-18 receptor are highly expressed in the

158 However, Th17 establishment also requires heterodimeric IL-23, but the mechanisms that regulate IL

159 pha subunit, which can still form functional heterodimeric IL-23.

160 The effects of heterodimeric IL-27 (p28/EBI3) have been implicated in t

161 Heterodimeric IL-27 (p28/EBV-induced gene 3) is an impor

162 creted as a cytokine, whereas in humans only heterodimeric IL-27 is present.

163 es Th2 immune responses through binding to a heterodimeric IL-33Ralpha (ST2L)/IL-1alpha accessory pro

164 kines interleukin 4 (IL-4) and IL-13 and the heterodimeric IL-4 receptor (IL-4R) complexes that they

165 ssfully produced a series of self-assembling heterodimeric inhibitors.

166 on agonist-induced inside-out activation of heterodimeric integrin receptors by a mechanism involvin

167 t selectively binds the beta7 subunit of the heterodimeric integrins alpha4beta7 and alphaEbeta7.

168 ell surface expression of TIM-3 by forming a heterodimeric interaction in cis through the highly rela

169 econd domain, capable of mediating homo- and heterodimeric interactions between JPH1 and JPH2 was ide

170 gest that the ability to establish homo- and heterodimeric interactions with resident JPHs may suppor

171 An enormous heterodimeric interface appears to be responsible for an

172 nied by rearrangement of the GluN1-GluN2 ATD heterodimeric interface, altering subunit orientation in

173 mbers of the communesin family from a single heterodimeric intermediate, including the first total sy

174 Heterodimeric KIF3AC and homodimeric KIF3AA and KIF3CC a

175 Heterodimeric KIF3AC and homodimeric KIF3AA displayed a

176 The properties of KIF3CC were not shared by heterodimeric KIF3AC and required the unique KIF3C-speci

177 Heterodimeric KIF3AC is a mammalian kinesin-2 that is hi

178 it confers specific properties to mammalian heterodimeric KIF3AC.

179 Heterodimeric kinesin family member KIF3AC is a mammalia

180 The beta2 integrins (CD11/CD18) are heterodimeric leukocyte adhesion molecules expressed on

181 sary and sufficient for generation of stable heterodimeric ligands with enhanced activity and can ena

182 Cohesins are deposited by a conserved heterodimeric loading complex composed of the Scc2 and S

183 nd their cleaved propeptides copurified as a heterodimeric low molecular weight complex that stimulat

184 et highly similar MTase subunits that form a heterodimeric M1M2S MTase.

185 ensive alkaloids isolated from ladybugs, the heterodimeric member chilocorine C possesses an alluring

186 f Nxf2-Nxt1, a gonad-specific variant of the heterodimeric messenger RNA export receptor Nxf1-Nxt1 an

187 Inhibition of the catalytic subunit of the heterodimeric methionine S-adenosyl transferase-2 (MAT2A

188 ed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existe

189 reporting a general approach to characterize heterodimeric mGluRs, our study opens new avenues to und

190 cling of naked TAS2R14 in the absence of the heterodimeric milieu.

191 es to promote dsDNA degradation by forming a heterodimeric molecular machine.

192 While engineered heterodimeric molecules have recently been a major focus

193 heterotrimeric kinesin-2, consisting of the heterodimeric motor subunits, kinesin family member 3A/3

194 ed AXR1 (AUXIN-RESISTANT1), a subunit of the heterodimeric NAE (E1 NEDD8-ACTIVATING ENZYME), as highl

195 Strikingly, co-depletion of NatA, a heterodimeric NAT complex that physically interacts with

196 fy AUXIN RESISTANT1 (AXR1), a subunit of the heterodimeric NEDD8 E1 activating enzyme, as a NEDD8-mod

197 The heterodimeric NeqAB complex assumes a closed, rigid conf

198 duce neurotoxins, the genes of a specialized heterodimeric neurotoxin predate the origin of rattlesna

199 interaction partner FosB before forming the heterodimeric NFATc3-FosB transcription factor complex,

200 The heterodimeric [NiFe] hydrogenase from Desulfovibrio fruc

201 DTX1 and DTX3L, functioning as a heterodimeric Notch E3 ligase, concertedly downregulate

202 amolecular hydrogelation triggered by mixing heterodimeric nucleopeptides.

203 Mucin 1 (MUC1) is a heterodimeric oncoprotein that is aberrantly overexpress

204 hese results highlight the importance of the heterodimeric organization of P1-P2 in the human stalk p

205 , these proteins are not well conserved with heterodimeric (p48/p58) primases in eukaryotes.

206 ration of a growth factor co-receptor with a heterodimeric partner and ligand known to regulate angio

207 uits a set of corepressors that includes its heterodimeric partner BTB and CNC homology 1, basic leuc

208 Fra-1 depletion or its heterodimeric partner c-Jun inhibits the proliferative a

209 A change in the heterodimeric partner of PPARalpha from RXRalpha to Sirt

210 mutation of the RXRA gene, which encodes the heterodimeric partner of PPARgamma.

211 integration site 1 for binding to the common heterodimeric partner Pbx1.

212 e specific binding of the VDR along with its heterodimeric partner RXR to the negative vitamin D resp

213 e form of the Ecdysone receptor (EcR) or its heterodimeric partner ultraspiracle (usp) causes GSC and

214 immune-regulatory functions regulated by its heterodimeric partner.

215 The AHR and heterodimeric partners AHR nuclear translocator and RELB

216 iosensor based on reversible exchange of the heterodimeric partners of green and red dimerization-dep

217 Moreover, we demonstrate activity for heterodimeric PDGF-AB ligand in the vigorous activation

218 oplasmic chaperone EspG forms complexes with heterodimeric PE-PPE substrates that are secreted from t

219 The heterodimeric peptide transporter consists of two homolo

220 p1s singularly "hijacked" p110 from p85:p110 heterodimeric PI3K, thereby abating BCR tonic signaling,

221 pili in Corynebacterium diphtheriae and the heterodimeric pili in Actinomyces oris, highlighting som

222 Integrin alphaIIbbeta3 is a highly abundant heterodimeric platelet receptor that can transmit inform

223 We demonstrate that interleukin-12, a heterodimeric pro-inflammatory cytokine consisting of th

224 ry antibodies to the alpha subunit of the Gs heterodimeric protein (GalphaS) into wild-type oocytes p

225 secretion system, M. tuberculosis releases a heterodimeric protein complex, containing a 6-kDa early

226 ll, Bajaj and colleagues report that CD98, a heterodimeric protein highly expressed in acute myeloid

227 coevolution provides accurate predictions of heterodimeric protein interfaces from sequence informati

228 ir RNA binding sites, the interfaces between heterodimeric protein molecules, the stems in RNA molecu

229 teins by building binding sites de novo into heterodimeric protein-protein interfaces and coupling li

230 for an unsolved map containing a 660-residue heterodimeric protein.

231 GF-beta) family of secreted, homodimeric and heterodimeric proteins controls the differentiation of m

232 gests that P. malariae expresses a family of heterodimeric proteins on its surface that have structur

233 This system generated covalent heterodimeric proteins upon co-transfections of plasmids

234 perones can regulate and control assembly of heterodimeric proteins, using interleukin 23 (IL-23) as

235 Because TCRs function as heterodimeric proteins, we used an emulsion-based RT-PCR

236 entially can be double-geranylgeranylated by heterodimeric Rab geranylgeranyltransferases (Rab-GGTs).

237 to Rad51 paralog function, we investigated a heterodimeric Rad51 paralog complex, RFS-1/RIP-1, and un

238 Nutrients switch the heterodimeric Rag GTPases among four different nucleotid

239 hat could improve the assembly and purity of heterodimeric reaction products, we sought crystal struc

240 The symmetry of a homodimer is broken in heterodimeric reaction-center structures, such as those

241 IL-25 signals through a heterodimeric receptor (IL-25R) composed of IL-17RA and

242 I interferons (IFN-lambdas) signal through a heterodimeric receptor complex composed of the IFN-lambd

243 a1, which then recruits IL-4Ralpha to form a heterodimeric receptor complex.

244 flammation and the locus containing IFNAR, a heterodimeric receptor for the type I interferons has be

245 ory cytokine that acts on target cells via a heterodimeric receptor formed by IL-17RA and IL-17RC sub

246 lex with human transferrin, showing how this heterodimeric receptor presents a large asymmetric ligan

247 -22Ralpha1) constructs could form functional heterodimeric receptor signaling complexes with the synt

248 Type III IFNs signal through a unique heterodimeric receptor, IFN-lambdaR1/interleukin-10R2 (I

249 of l- and d-amino acid actions on the sweet heterodimeric receptor.

250 enin signaling is independent of the FZD/LRP heterodimeric receptors and Wnt ligands.

251 Integrins are heterodimeric receptors composed of alphabeta subunits,

252 Integrins are a family of heterodimeric receptors that bind to components of the e

253 further exploited for a variety of homo- or heterodimeric receptors to achieve signaling, especially

254 acea, and Ktedonobacter racemifer-as soluble heterodimeric recombinant proteins in E. coli for the fi

255 lved in innate immune signaling, notably the heterodimeric S100 calcium-binding proteins S100a8 and S

256 n, our results show that the expression of a heterodimeric secretory protein can be improved by harmo

257 present the first four crystal structures of heterodimeric septin complexes.

258 Here, we focus on antiparallel homo- or heterodimeric small multidrug resistance proteins and ex

259 suggests deep functional conservation of the heterodimeric SMF1 and SCRM1 unit is required to activat

260 ation of the same [4Fe-4S](2+) cluster-bound heterodimeric species is also observed by having first o

261 These heterodimeric species may allow the tuning of the chaper

262 eby transition from a homodimeric state to a heterodimeric state in which the coiled-coil region of W

263 We found the CEACAM6-CEACAM8 heterodimeric state to be substantially favored energeti

264 neering is challenging, owing to the complex heterodimeric structure of the receptor and to competiti

265 pUL17 and pUL25 form a heterodimeric structure, the capsid vertex-specific comp

266 We show that PA-PB1 forms a stable heterodimeric submodule that can strongly interact with

267 by facilitating redistribution of its small heterodimeric subunit Rnr2-Rnr4 from the nucleus to the

268 Pol I mutants lacking either the heterodimeric subunit Rpa34.5/Rpa49 or the C-terminal pa

269 T cells are defined by a heterodimeric surface receptor, the T cell receptor (TCR

270 Here, the heterodimeric TAP complex was purified and reconstituted

271 to redirect the activity of T cells, normal heterodimeric TCRs or synthetic chimeric Ag receptors (C

272 Ribonucleotide reductase (RNR), which is a heterodimeric tetramer composed of RRM1 and RRM2 subunit

273 talyzed by ribonucleotide reductase (RNR), a heterodimeric tetramer enzyme in mammalian cells, having

274 re, we describe the 2.7-A X-ray structure of heterodimeric Thermus thermophilus multidrug resistance

275 e reveal the evolutionary trajectory for the heterodimeric TMO5/LHW transcription factor complex, whi

276 f extrinsic and intrinsic signals to control heterodimeric transcription factor complex formation pro

277 NX1/CBFbeta (core binding factor [CBF]) is a heterodimeric transcription factor complex that is frequ

278 Binding Factors (CBFs) are a small group of heterodimeric transcription factor complexes composed of

279 Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor containing an inducib

280 HIF is an alpha/beta-heterodimeric transcription factor that regulates the ex

281 ccumulation of the HIFalpha subunit of these heterodimeric transcription factors comparable with hypo

282 Hypoxia-inducible factors (HIF) are heterodimeric transcription factors that allow cells to

283 oxia inducible factors (HIFs) are alpha/beta heterodimeric transcription factors that direct multiple

284 type II nuclear receptors (NRs) function as heterodimeric transcription factors with the retinoid X

285 rt by promoting the phosphorylation of their heterodimeric transcriptional activators (e.g., White Co

286 studies show that a ligand-containing Pd-Ag heterodimeric transition state (TS) favors the desired r

287 P2 from the same taxon can form a functional heterodimeric translocation complex.

288 The heterodimeric transmembrane alphav integrin receptors ha

289 The integrins are a family of 24 heterodimeric transmembrane cell surface receptors.

290 Integrins are heterodimeric transmembrane protein receptors consisting

291 They are heterodimeric transmembrane proteins that bind extracell

292 Integrins are heterodimeric transmembrane receptors consisting of alph

293 Integrins comprise a family of 24 heterodimeric transmembrane receptors that mediate cell

294 lex class I (MHC I) molecules depends on the heterodimeric transporter associated with antigen proces

295 These heterodimeric tryptase inhibitors demonstrate superior a

296 These heterodimeric tryptase inhibitors demonstrate the power

297 Cells producing a heterodimeric Tsr receptor containing only one functiona

298 between residues 130 and 131 and generated a heterodimeric unstable metabolite TSLP (29-130 + 131-159

299 cking VHH class (JIK-B8) were expressed as a heterodimeric VHH-based neutralizing agent (VNA2-PA).

300 Collectively, these data suggest that heterodimeric VHH-based neutralizing agents may function