ライフサイエンスコーパス: heterotetramer

1 57, or alphaSer116 (NHases are alpha 2beta 2 heterotetramers).

2 or alphaSer(112) (NHases are alpha(2)beta(2)-heterotetramers).

3 peptide binds to a hydrophobic pocket in the heterotetramer.

4 tor complex AP2 is thought to be an obligate heterotetramer.

5 ntified L2-specific receptor, the annexin A2 heterotetramer.

6 utyryl-CoA and n-butyryl-CoA and exists as a heterotetramer.

7 e two MEM83 epitopes across the LFA-1/ICAM-1 heterotetramer.

8 pstream segments of MYPT1 via formation of a heterotetramer.

9 ubsequently diverged into an alpha(2)beta(2) heterotetramer.

10 stal structure of the full-length human GINS heterotetramer.

11 build a model of the yeast m1A58 tRNA Mtase heterotetramer.

12 ly with nanomolar affinity to form a 1:1:1:1 heterotetramer.

13 te faces of the neuroligin-1 dimer to form a heterotetramer.

14 ners can bridge each other at the top of the heterotetramer.

15 d physically blocking formation of the H3/H4 heterotetramer.

16 and purified from Escherichia coli as a J2K2 heterotetramer.

17 the polypeptides of the MADH alpha(2)beta(2) heterotetramer.

18 nA dimer, and the two proteins form a stable heterotetramer.

19 heterodimer and a RAD51B/RAD51C/RAD51D/XRCC2 heterotetramer.

20 eractions control catalysis in a recombining heterotetramer.

21 dily displaces DNMT3L from the DNMT3A:DNMT3L heterotetramer.

22 conversion of the latter to the native BCKD heterotetramer.

23 s specifically associate to form an A(2)B(2) heterotetramer.

24 se-8 was not further processed to its active heterotetramer.

25 xpressed as a catalytically inactive, labile heterotetramer.

26 teolytic cleavage and the active enzyme is a heterotetramer.

27 r alpha-like subunits form either a homo- or heterotetramer.

28 inhibit the activity of the mature caspase-3 heterotetramer.

29 (beta) subunits associated as an alpha2beta2 heterotetramer.

30 (D) in the lower picomolar range, yielding a heterotetramer.

31 nger displaced DNMT3L from the DNMT3A:DNMT3L heterotetramer.

32 orresponds to a specific subunit forming the heterotetramer.

33 stituted by AP3beta3B in the neuron-specific heterotetramer.

34 the two homodimers coassemble in forming the heterotetramer.

35 a Sec23-Sec24 heterodimer and a Sec13-Sec31 heterotetramer.

36 pported quaternary structure of the spectrin heterotetramer.

37 e Sig1R bound directly to GluN1/GluN2A NMDAR heterotetramers.

38 OAPs but can coassemble with M23 in OAPs as heterotetramers.

39 that the hybrids have predominant amounts of heterotetramers.

40 alculated mass consistent with a pair of RAG heterotetramers.

41 TRPC3 and TRPC6 form heterotetramers.

42 human EGFR type 2 can associate as homo- and heterotetramers.

43 suggesting that the channels are composed of heterotetramers.

44 ontributes to the extraordinary stability of heterotetramers.

45 appears to reversibly self-associate to form heterotetramers.

46 erwise trapped mutant heterodimers to active heterotetramers.

47 ic species, followed by conversion to active heterotetramers.

48 and C-terminal interaction in both homo- and heterotetramers.

49 2 but, in vivo, kainate receptors are likely heterotetramers.

50 Ps), PIP1 and PIP2 monomers interact to form heterotetramers.

51 idate the coassembly of the peptides to form heterotetramers.

52 gatively cooperative formation of asymmetric heterotetramers.

53 bfamilies, such as Eag and Erg, fail to form heterotetramers.

54 Kv channel subfamily may co-assemble to form heterotetramers.

55 endence and kinetics, carried by K(v)7.2/7.3 heterotetramers, 4% activated at the resting membrane po

56 Before the broken RNAs were ligated by the heterotetramer, a methyl group was added to the 2'-OH gr

57 sh that ChsE1-ChsE2 forms an alpha(2)beta(2) heterotetramer, a new architecture for an ACAD.

58 ha(2) and alpha(4) endonucleases but forms a heterotetramer: a dimer of two heterodimers of the catal

59 Annexin A2 (A2) heterotetramer (A2.p11)(2) is a key profibrinolytic comp

60 ace plasmon resonance analysis showed that a heterotetramer (A2t) of p11 and annexin A2, but not p11

61 recently identified receptor, the annexin A2 heterotetramer (A2t).

62 that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with p11 (S100A10).

63 The protein complex annexin A2 heterotetramer (AIIt) is an important plasminogen recept

64 Structures of the heterotetramer alone and heterohexamer bound to promoter

65 of two subunits, alpha and beta, that form a heterotetramer (alpha(2)beta(2)) in solution.

66 ultimately dictates the high fidelity of the heterotetramer (alpha*beta*)2 assembly, is the binding o

67 complex of Bacillus stearothermophilus is a heterotetramer (alpha2beta2) of E1alpha and E1beta polyp

68 xes reveal two distinct architectures: a 2:2 heterotetramer and a continuous ligand/receptor assembly

69 t interact physically with the (CenH3-H4)(2) heterotetramer and are required for the deposition of Ce

70 t they are probably shielded in the spectrin heterotetramer and become exposed only after CaM binds a

71 ied that the ORF6 protein was an alpha2beta2 heterotetramer and direct evidence for this came from ma

72 or, which in yeast consists of the Get1/Get2 heterotetramer and in mammals of the WRB protein (trypto

73 HJURP binding disrupts the Mis18alpha-beta heterotetramer and removes Mis18alpha from centromeres.

74 e in coordinating catalysis within the XerCD heterotetramer and suggest that the interactions between

75 2 interact to form a (IFT81)(2)(IFT74/72)(2) heterotetramer and that IFT27 and IFT25 form a heterodim

76 that p110 and p107 are subunits of a 430-kD heterotetramer and that they both originate from the sam

77 l rigidity to both the subnucleosomal CENP-A heterotetramer and the corresponding assembled nucleosom

78 hemical properties of both the reconstituted heterotetramer and the heterodimer of the p125 and p50 s

79 The structures show that MRP1/MRP2 is a heterotetramer and, despite little sequence homology, ea

80 ombine to make a presumptive alpha(2)beta(2) heterotetramer and, in particular, the location of the s

81 site prevented the formation of a CITFA2-LC8 heterotetramer and, in vivo, was lethal, affecting assem

82 of E1p and E3 demonstrated 40 copies of E1p heterotetramers and 20 copies of E3 dimers associated wi

83 transthyretin and human/murine transthyretin heterotetramers and compared their structures and biophy

84 Both AP-1 complexes are heterotetramers and differ only in their 50-kD mu1A or m

85 otrimers, M(x)S-Au-Pt-Fe(3)O(4) (M = Pb, Cu) heterotetramers and higher-order oligomers based on the

86 These helix-heterotetramers and their derivatives are sufficiently s

87 eins are catalytically inactive, do not form heterotetramers, and do not bind pyridoxal phosphate.

88 a phospholipid-binding protein that forms a heterotetramer (annexin II-p11 heterotetramer; A2t) with

89 sent in the prototypical linear antiparallel heterotetramer as well as recently reported inter-strand

90 : H1, H2A/H2B heterodimers followed by H3/H4 heterotetramers, as predicted from their spatial organiz

91 ctures for the GluR6/KA2 ATD heterodimer and heterotetramer assemblies.

92 ovides a structural outlook of the FXIIIA2B2 heterotetramer assembly, its association and dissociatio

93 ild-type human keratin-1/keratin-10 helix 1B heterotetramer at 3.0 angstrom resolution.

94 with AnxA2 in association with S100A10 as a heterotetramer at the cell surface in a Ca(2+)-dependent

95 activate TERT, probably by facilitating GABP heterotetramer binding.

96 s are homodimers and prokaryotic enzymes are heterotetramers, both prokaryotic and eukaryotic type II

97 t4/5 complex is dominated by a single Get4/5 heterotetramer bound to one monomer of a Get3 dimer, unc

98 erminal region of RAG2 stabilizes the RAG1/2 heterotetramer but destabilizes the RAG-DNA precleavage

99 rate that Asf1 blocks formation of the H3-H4 heterotetramer by a mechanism that likely involves occlu

100 o demonstrate the occurrence of diverse AP-1 heterotetramers by combinatorial assembly of various gam

101 Our results show that PIP2-PIP1 heterotetramers can assemble with 3:1, 1:3, or 2:2 stoic

102 tetramer channel, in astrocytes as homo- and heterotetramer channels together with KIR5.1.

103 Calcium-bound CaM2 dissociates from CNGC18/8 heterotetramer, closing the channel and initiating a dow

104 lso report the structure of a (Cse4 : H4)(2) heterotetramer; comparison with the structure of the Scm

105 ABPbeta formed a stable heterodimer, with no heterotetramer complex detected.

106 ests that FDM1 may exist as a homodimer in a heterotetramer complex in vivo.

107 inity when they are part of the PXR/RXRalpha heterotetramer complex than they do when each ligand-bin

108 r p53 decreases DNMT3A activity by forming a heterotetramer complex with DNMT3A.

109 show quite clearly that the heterodimer and heterotetramer complexes do not behave in solution as di

110 functional NMDA receptor is thought to be a heterotetramer composed mainly of two NR1 and two NR2 su

111 The receptor is a heterotetramer composed of a family of related subunits.

112 key enzyme in chromosomal replication, is a heterotetramer composed of the p125, p50, p68 and p12 su

113 We report here that a stable heterotetramer composed of two bacterial proteins, Pnkp

114 Sec13p/31p is a heterotetramer composed of two copies of Sec13p and two

115 AGPase is heterotetramer composed of two small and two large subun

116 They signal by assembling a receptor heterotetramer composed of two TbetaRI:TbetaRII heterodi

117 otropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subun

118 The functional NMDA receptors, heterotetramers composed mainly of two NR1 and two NR2 s

119 We show that heterotetramers composed of 2alpha- and 2beta-tryptase p

120 s the transactivation potential of homo- and heterotetramers composed of different p63 isoforms and t

121 NMDARs are heterotetramers composed of GluN1 and GluN2 subunits, wh

122 Heterotetramers composed of murine and human subunits ar

123 NMDA receptors are obligate heterotetramers composed of two GluN1 and typically two

124 d cyclic nucleotide-gated (CNG) channels are heterotetramers comprised of both CNGA1 and CNGB1 subuni

125 (15)N-Edited NOESY shows the 2:2 heterotetramer comprises two different homodimers, rathe

126 The polymerase delta complex is a heterotetramer comprising the catalytic subunit POLD1 an

127 The enzyme is a heterotetramer comprising two GyrA and two GyrB subunits

128 uce a functional Kv channel by investigating heterotetramers comprising combinations of full-length K

129 Intriguingly, these complexes appear as heterotetramers, comprising two HD-ZIPIII and two ZPR mo

130 Coagulation factor XIII (FXIII) is a heterotetramer consisting of 2 catalytic A subunits (FXI

131 RNR is a heterotetramer consisting of two large RRM1 subunits and

132 soluble pm142-pm143 complex appears to be a heterotetramer consisting of two molecules of pm142 asso

133 her plant ADP-glucose pyrophosphorylase is a heterotetramer consisting of two subunit types, which ha

134 These channels are heterotetramers consisting of two homologous subunits, G

135 Annexin II is a heterotetramer, consisting of two 11-kDa (p11) and two 3

136 The annexin A2 (A2) heterotetramer, consisting of two copies of A2 and two c

137 technologies, we have demonstrated that the heterotetramer constituents bind to C-1-P.

138 Although the annexin a2-p11 heterotetramer constituents do not bind the lipid C-1-P

139 ceramide 1-phosphate and the annexin a2-p11 heterotetramer constituents.

140 model that considers A2AR-D2R heteromers as heterotetramers, constituted by A2AR and D2R homodimers,

141 The MoFe protein folds as a heterotetramer containing two copies each of the homolog

142 The nitrogenase MoFe protein is a heterotetramer containing two unique high-nuclearity met

143 lation, RNAs repaired by bacterial Pnkp/Hen1 heterotetramer could not be cleaved again by the ribotox

144 also TRPC1/4alpha, TRPC1/4beta, and TRPC1/5 heterotetramer currents.

145 se 3alpha (IDH3alpha), a subunit of the IDH3 heterotetramer, decreased alpha-ketoglutarate levels and

146 r 3-fold axis of symmetry that relates three heterotetramers, each of which is composed of two tightl

147 ngly, the kinetochore recruits two Mad1-Mad2 heterotetramers for every Bub3-Bub1 molecule.

148 re co-expressed in E. coli, HGPRT-I.HGPRT-II heterotetramers form.

149 Mis18alpha-beta heterotetramer formation is required for Mis18BP1 bindin

150 Co-expression in Escherichia coli results in heterotetramer formation with a 3000-fold increase in en

151 3 binding to the membrane insertase supports heterotetramer formation, and phosphatidylinositol bindi

152 ural basis for TbPRMT1 ENZ activation by PRO heterotetramer formation, which is conserved across all

153 homotetramers as the rate-limiting step for heterotetramer formation.

154 efinitive biochemical evidence of endogenous heterotetramer formation.

155 and DNcSHMT tetramers, and the formation of heterotetramers from cSHMT and DNcSHMT homodimers does n

156 ons of the two active sites in the human E1b heterotetramer harboring the reaction intermediate are i

157 properties of an epsilon -globin-containing heterotetramer (Hb Gower-2) both in vitro as well as in

158 d by structural modeling predictions for ASL heterotetramer/homotetramer formation.

159 rt the crystal structure of a subnucleosomal heterotetramer, human (CENP-A-H4)(2), that reveals three

160 ptor complex that is either a heterodimer or heterotetramer (i.e. a dimer of dimers).

161 f the promoter regions was bound by a single heterotetramer, i.e. the flgAMN and flgBCD operons are c

162 ) per CP heterodimer and eight Ca(2+) per CP heterotetramer, (iii) establish the protein-to-Ca(2+) mo

163 ssium channel Kir4.1 forms the Kir4.1/Kir5.1 heterotetramer in the basolateral membrane of the distal

164 This TA system forms an alpha(2)beta(2) heterotetramer in the crystal and in solution.

165 ric intermediate to a native alpha(2)beta(2) heterotetramer in the E1 assembly pathway.

166 and protein disulfide isomerase coexist as a heterotetramer in the ER, we discuss the effects of Hyp

167 s 46 +/- 15 nm, indicating that the spectrin heterotetramer in the native membrane skeleton is a frac

168 on, revealing a highly symmetric Cmu1-KWL1-b heterotetramer in which each KWL1-b monomer interacts wi

169 o bacterial enzymes in that it consists of a heterotetramer in which the alpha-subunits contain the a

170 eranyl diphosphate synthase from Mentha is a heterotetramer in which the large subunit shares functio

171 g reveal that the peptides form a mixture of heterotetramers in 3:1, 2:2, and 1:3 stoichiometries, in

172 efficiently expressed in Escherichia coli as heterotetramers in a temperature-dependent manner.

173 ha- and beta-globin subunits into hemoglobin heterotetramers in both primitive and definitive erythro

174 aA3-crystallins associate predominantly into heterotetramers in equilibrium with heterodimers.

175 ys of communication between heterodimers and heterotetramers in the hetero-octamer.

176 s suggest that an observed asymmetry between heterotetramers in the holoenzyme contributes to interac

177 ter channel protein aquaporin-4 (AQP4) forms heterotetramers in the plasma membrane made of the M23-A

178 Like histone H3, CENP-A can form CENP-A-H4 heterotetramers in vitro.

179 eta-crystallins associate predominantly into heterotetramers in vitro.

180 n of a H3-H4 chaperone binding to (H3-H4)(2) heterotetramers in vivo.

181 strate that Rtt106 interacts with (H3-H4)(2) heterotetramers in vivo.

182 r dimerize through SAV1 WW domains to form a heterotetramer, in which MST2 undergoes trans-autophosph

183 Characterization of the cSHMT/DNcSHMT heterotetramers indicates that DNcSHMT and cSHMT monomer

184 The role of beta(116His) (G-18) in heterotetramer-induced stabilization of the bond with ox

185 The role of heterotetramer interaction sites in assembly and autoxid

186 ion, and phosphatidylinositol binding at the heterotetramer interface stabilizes the insertase for ef

187 DNMT3A.DNMT3A homotetramer and DNMT3A.DNMT3L heterotetramer interfaces.

188 The 230-kilodalton RAG1-RAG2 heterotetramer is 'Y-shaped', with the amino-terminal do

189 This heterotetramer is capable of a low-level receptor transp

190 evealed that the overall architecture of the heterotetramer is highly similar to that of the previous

191 nary organization of the alphabetagammagamma heterotetramer is poorly understood and contradictory pa

192 ural model for a XRCC1 x DNA ligase IIIalpha heterotetramer is proposed as a core base excision repai

193 -alpha-helical bundle are such that only the heterotetramer is stable in solution; corresponding homo

194 only weakly stimulated by PCNA, whereas the heterotetramer is strongly stimulated to a level with a

195 alpha(2)beta(2) The overall structure of the heterotetramer is the same as that observed by cryo-EM m

196 altered interactions within the recombining heterotetramer lead to changes in the relative concentra

197 r alternatively, formation of the SLIP1-SLBP heterotetramer may facilitate removal of SLBP from the h

198 Plant AGPases are heterotetramers, most of which are activated by 3-phosph

199 DNMT3A function when forming the DNMT3A:p53 heterotetramer, no longer displaced DNMT3L from the DNMT

200 AP2, a heterotetramer of alpha, beta, mu and sigma subunits, li

201 f the oxygen carrier, haemoglobin A (HbA), a heterotetramer of alpha- and beta-haemoglobin subunits.

202 t during the assembly of the alpha(2)beta(2) heterotetramer of human mitochondrial branched-chain alp

203 tinating enzyme converted the p110:p107 PEPC heterotetramer of immature proteoid roots into a p107 ho

204 ectifying potassium channel Kir4.1/Kir5.1 (a heterotetramer of Kir4.1/Kir5.1) in the DCT is essential

205 Centralspindlin, a constitutive 2:2 heterotetramer of MKLP1 (a kinesin-6) and the non-motor

206 ate the origins of vertebrate haemoglobin, a heterotetramer of paralogous alpha- and beta-subunits th

207 ESCRT-I is a heterotetramer of Vps23, Vps28, Vps37, and Mvb12.

208 ent and that this current could be formed by heterotetramers of active and silent subunits.

209 w that ESCRT-0 forms mostly heterodimers and heterotetramers of Hrs and STAM when analyzed in the pre

210 his conductance is most probably a result of heterotetramers of Kir2 gene products, with this regulat

211 Kv7 (KCNQ) channels, formed as homo- or heterotetramers of Kv7.4 and Kv7.5 alpha-subunits, are i

212 r channel aquaporin-4 (AQP4) is expressed as heterotetramers of M1 and M23 isoforms in which the pres

213 operties and a long evolutionary separation, heterotetramers of potato small subunit and maize large

214 umed to be the deposition of a histone H3-H4 heterotetramer onto DNA.

215 results indicate that Rtt106 deposits H3-H4 heterotetramers onto DNA and provide the first descripti

216 vidence that the two active sites in the E1b heterotetramer operate independently during the ThDP-dep

217 inhibit the formation of active FlhD(2)C(2) heterotetramers or inhibit FlhD(2)C(2) binding to DNA.

218 from proteolytic degradation as an inactive heterotetramer, or alternatively, formation of the SLIP1

219 Concomitant with formation of the active heterotetramer, p20 is autoprocessed to p17.

220 y rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a key role in mediating the effect

221 ility of each tetramer and show that the 2:2 heterotetramer predominates.

222 This designed heterotetramer preferentially recombined a particular pa

223 izes to mediate formation of an (H3.3/H4)(2) heterotetramer prior to chromatin deposition.

224 e irreversible step in assembly results from heterotetramer rather than heterodimer dissociation and

225 ion of Kir2.6 as a subunit in a Kir2 channel heterotetramer reduces the abundance of Kir2 channels on

226 Because NMDA-Rs are obligatory heterotetramers requiring the GluN1 subunit, it is criti

227 However, some heterotetramers retained varied degrees of function depe

228 be deduced from the earliest origins of the heterotetramer/scaffold coat to its multiple manifestati

229 dehydrogenase (SDH), is an integral-membrane heterotetramer (SDHABCD) that links two essential energy

230 -Sss1, the Sec63-Sec71-Sec72 trimer, and the heterotetramer Sec62-Sec63-Sec71-Sec72, respectively.

231 The peptides within the heterotetramer segregate in forming the homodimer subuni

232 possibility using two randomly chosen helix-heterotetramers, showing that their mechanical propertie

233 Structural analysis of the CsrA/FliW heterotetramer shows that FliW interacts with a C-termin

234 eceptor recruitment to the ligand, induced a heterotetramer signaling complex, and propagated Smad2 a

235 An activated SCF complex, a heterotetramer (Skp1, Cul-1, beta-TrCP [F-box protein],

236 Assembly of T150D K5 is arrested at the heterotetramer stage coinciding with increased heat shoc

237 y specifying a unique spatial arrangement of heterotetramer subunits.

238 D subunits form the carboxyltransferase (CT) heterotetramer that catalyzes the second partial reactio

239 The MoFe protein is an alpha(2)beta(2) heterotetramer that harbors two types of complex metallo

240 ex forms a 2:2 high-affinity (K(D) < 0.9 nM) heterotetramer that is also incapable of binding histone

241 inase Pak2 is cleaved by caspase 3 to form a heterotetramer that is constitutively activated followin

242 Adaptor protein complex 3 (AP-3) is a heterotetramer that is involved in signal-mediated prote

243 ations and binds more Ca(2+) ions, forming a heterotetramer that is poised to compete with microbial

244 The adaptor protein 1 (AP1) complex is a heterotetramer that participates in cargo sorting into c

245 omplex 1 (AP-1) is an evolutionary conserved heterotetramer that promotes vesicular trafficking betwe

246 These proteins form a stable heterotetramer that remains bound to the mRNA throughout

247 These two proteins form a heterotetramer that then combines with six C1q subunits.

248 complexes (APs) are evolutionarily conserved heterotetramers that couple cargo selection to the forma

249 ed altered-specificity Cre monomers can form heterotetramers that recombine nonidentical asymmetric s

250 ugh the caspase-3 subunits reassemble to the heterotetramer, the activity return is low after the pro

251 at the tracking assembly comprises a UvrA2B2 heterotetramer, the configurations of the damage engagem

252 In a full-length heterotetramer, the LBDs could potentially be arranged e

253 xpression of Kir3.1/Kir3.2 and Kir3.1/Kir3.4 heterotetramers, the GIRK channels found in the brain an

254 heir self-assembly into a higher order H3/H4 heterotetramer, their deposition into nucleosomes by hum

255 demonstrate Mis18alpha and Mis18beta form a heterotetramer through their C-terminal coiled-coil doma

256 tiator caspases cannot reassociate to active heterotetramer, thus resulting in irreversible inhibitio

257 nd may enable cross-linking of multiple AP-4 heterotetramers, thus contributing to the assembly of th

258 ting, we describe the binding of the FlhD2C2 heterotetramer to the promoter regions of four class II

259 SLBP at Thr171 promotes dissociation of the heterotetramer to the SLIP1-SLBP heterodimer.

260 on of trans-suppressor subunits (T119M) into heterotetramers to destabilize the dissociative transiti

261 ividual subtypes within defined concatenated heterotetramers to the shaping of Ca(2+) signals.

262 They are heterotetramers, typically composed of two GluN1 and two

263 tures establish that PXR and RXRalpha form a heterotetramer unprecedented in the nuclear receptor fam

264 vering an intriguing asymmetry in the Get4/5 heterotetramer upon Get3 binding.

265 Heterotetramer voltage-gated K(+) (KV) channels KV2.1/KV

266 We show that R2 monomers within a heterotetramer were both necessary and sufficient to dic

267 KvLm heterotetramers were produced by cell-free expression, p

268 l in isolation, but which can form an active heterotetramer when combined.

269 , and B) that self-assemble into the desired heterotetramer when mixed in a 1:1:2 molar ratio.

270 of 1:3 and have solved the structure of the heterotetramer which we believe represents a novel strat

271 Acidic residues in the core of the E1b heterotetramer, which align with the proton-wire residue

272 ax counterpart, dimerizes to form a bivalent heterotetramer, which explains how Myc can upregulate ex

273 and disassembles the heterohexamer into two heterotetramers, which are unable to bind the promoter D

274 A was also shown to support the formation of heterotetramers, which creates a mechanism for NA to obt

275 lity from a set of recently engineered helix-heterotetramers whose mechanical properties have yet to

276 e dissect the ordered assembly of the RAG1/2 heterotetramer with 12RSS and 23RSS DNAs.

277 1 domain and the ligase IIIalpha domain is a heterotetramer with 2:2 stoichiometry.

278 otably, two TIGIT/PVR dimers assemble into a heterotetramer with a core TIGIT/TIGIT cis-homodimer, ea

279 The structure reveals a heterotetramer with a distinctive, elongated quaternary

280 enous FXIII-B subunits to form an FXIII-A2B2 heterotetramer with a half-life of 8.5 days, similar to

281 er and more ordered pore are seen in the 1:1 heterotetramer with an antiparallel helix arrangement.

282 ered large subunit gives rise to a maize AGP heterotetramer with decreased sensitivity to its negativ

283 DNA polymerase alpha-primase (pol-prim) is a heterotetramer with DNA polymerase and primase activitie

284 ins of Mdm12 and Mmm1 associate into a tight heterotetramer with equimolecular stoichiometry.

285 ional rigidity to the initial subnucleosomal heterotetramer with histone H4 as does CENP-A.

286 atic activity and resulted in a fully active heterotetramer with kinetic constants similar to those o

287 -Myc and c-Src, and AnxA2 forms a functional heterotetramer with S100A10 to promote tumor motility.

288 lyceraldehyde-3-phosphate dehydrogenase as a heterotetramer with the Escherichia coli glyceraldehyde-

289 Our results show the formation of a heterotetramer with three nuclear receptors binding to t

290 olution, the peptides form a stable, helical heterotetramer with tight packing in the most solvent-pr

291 BchN and BchB arranged as an alpha(2)beta(2) heterotetramer with two active sites for substrate reduc

292 y, the exon 2-deleted ASL variant may form a heterotetramer with wild type or mutant ASL, causing mar

293 ins in bacteria resulted in the formation of heterotetramers with a cSHMT/DNcSHMT subunit ratio of 1.

294 suggest that sQseD regulates ler by forming heterotetramers with another LTTR.

295 Activated p53 molecules formed nuclear heterotetramers with Delta40p53 and altered downstream p

296 exist as homotetramers (GIRK2 and GIRK4) or heterotetramers with nonfunctional homomeric subunits (G

297 TRPC5 in homotetramers, whereas when forming heterotetramers with TRPC1, the sensitivity was approxim

298 rogenase (ACAD) enzymes that are alpha2beta2 heterotetramers with two active sites.

299 at both transporters exist as both homo- and heterotetramers, with a predominance of homotetramers.

300 xists as two distinct oligomeric assemblies: heterotetramer (YoeB-YefM2-YoeB) and heterohexamer (YoeB