ライフサイエンスコーパス: heterotrimeric

1 Despite the discovery of heterotrimeric alphabetagamma G proteins approximately 2

2 tes many cellular proteins, in the case of a heterotrimeric aminoacyl-tRNA synthetase complex, the ag

3 The enzyme family of heterotrimeric AMP-dependent protein kinases is activate

4 iverse array of processes and is part of the heterotrimeric Bag6 complex, which also includes ubiquit

5 H, and the RING-finger protein MAT1 form the heterotrimeric CDK-activating kinase (CAK) complex which

6 he evolutionarily conserved Sec61 complex, a heterotrimeric channel that comprises the Sec61p/Sec61al

7 Prior studies suggested that the heterotrimeric ciliary kinesin may be dispensable for ce

8 e, which encodes the common motor subunit of heterotrimeric ciliary kinesins.

9 The RAD9A-HUS1-RAD1 (9-1-1) complex is a heterotrimeric clamp that promotes checkpoint signaling

10 microscopy structure of the ATPgammaS-bound, heterotrimeric cohesin ATPase head module and the 2.1- a

11 Collectively, the data suggest that the heterotrimeric complex can work as a [2Fe-2S](2+) cluste

12 inase (AMPK) is an obligatory alphabetagamma heterotrimeric complex carrying a carbohydrate-binding m

13 protein phosphatase 2A (PP2A) functions as a heterotrimeric complex composed of a catalytic (C), scaf

14 Molecular motor activity is driven by a heterotrimeric complex comprised of KIF3A and KIF3B or K

15 lB1 from Sulfolobus solfataricus exists as a heterotrimeric complex in cell extracts.

16 Retromer is a heterotrimeric complex that associates with endosomal me

17 n support of such functions, C9orf72 forms a heterotrimeric complex with SMCR8 and WDR41 that is recr

18 LKB1 is activated by forming a heterotrimeric complex with STRAD and MO25.

19 tions of which are poorly understood, form a heterotrimeric complex with Sufu and Gli.

20 Mammalian AMPK is a heterotrimeric complex, and its catalytic alpha subunit

21 t emerged that apo GRX3 and apo BOLA2 form a heterotrimeric complex, composed by two BOLA2 molecules

22 mation of the functional AMPK alphabetagamma heterotrimeric complex.

23 -C subunits interact and form a stable NF-Y heterotrimeric complex.

24 and all possible betagamma-dimers to form a heterotrimeric complex.

25 involves a conformational switch within the heterotrimeric complex.

26 VGSCs in mammalian brain are heterotrimeric complexes of alpha and beta subunits.

27 and (according to this paradigm) operate as heterotrimeric complexes of catalytic-alpha and regulato

28 Although each R7-RGS subtype forms heterotrimeric complexes with Gbeta5 and R7-RGS-binding

29 SMAD3 transcription factors, which then form heterotrimeric complexes with SMAD4 and cooperate with c

30 ed ability of the G-protein subunits to form heterotrimeric complexes, including betagamma-dimers pre

31 elucidate the thermodynamic properties of a heterotrimeric DNA complex that portrays the structure o

32 The original purification of the heterotrimeric eIF4F was published over 30 years ago.

33 as the Werner syndrome protein (WRN) and the heterotrimeric eukaryotic ss-DNA binding protein RPA.

34 in EIF2S3, encoding the gamma subunit of the heterotrimeric eukaryotic translation initiation factor

35 The heterotrimeric eukaryotic translation initiation factor

36 Addition of the KAP subunit to generate the heterotrimeric FLA8/10/KAP relieved this inhibition, thu

37 te directly with CMG, including Ctf4 and the heterotrimeric fork protection complex (Csm3/Tof1 and Mr

38 hibitor of B55alpha- and B56delta-containing heterotrimeric forms of PP2A.

39 Upon photoactivation of rhodopsin, the heterotrimeric G protein (transducin) is activated, resu

40 G protein-coupled receptor-mediated heterotrimeric G protein activation is a major mode of s

41 be driven by an unconventional mechanism of heterotrimeric G protein activation that operates in lie

42 eptide agonist permitting receptor-dependent heterotrimeric G protein activation.

43 leotide exchange Factor (GEF) that activates heterotrimeric G protein alpha subunits (Galpha) and ser

44 ty and is a chaperone for several classes of heterotrimeric G protein alpha subunits in vertebrates.

45 ne nucleotide exchange (GEF) activity toward heterotrimeric G protein alpha subunits of the i, q, and

46 GNAQ and GNA11 are heterotrimeric G protein alpha subunits, which are mutat

47 ial genes that encode positive regulators of heterotrimeric G protein alpha subunits.

48 ist activation, as assessed by activation of heterotrimeric G protein and allosteric coupling between

49 A role for heterotrimeric G protein betagamma subunits was shown by

50 The heterotrimeric G protein complex, consisting of canonica

51 Plants and some protists have heterotrimeric G protein complexes that activate spontan

52 GDD and provide insights how perturbation in heterotrimeric G protein function contributes to the dis

53 utic agent exerts its effects via perturbing heterotrimeric G protein function, despite a plethora of

54 Clearly, Ric-8 has a profound influence on heterotrimeric G protein function.

55 rily through the adenylyl cyclase-inhibiting heterotrimeric G protein G(i).

56 upled receptor (GPCR) that couples(1) to the heterotrimeric G protein G(s).

57 Heterotrimeric G protein Galpha13 is known to transmit G

58 Pharmacological inhibition of heterotrimeric G protein Galphai or PI3K signaling and s

59 e B lymphocyte surface receptors, triggering heterotrimeric G protein Galphai subunit guanine nucleot

60 red an interaction between PP1calpha and the heterotrimeric G protein Gbeta1 subunit.

61 ptor Ste2, in an active state coupled to the heterotrimeric G protein Gpa1-Ste4-Ste18.

62 ivative, was validated using cell-free aGPCR/heterotrimeric G protein guanosine 5'-3-O-(thio)triphosp

63 f the C terminus of the alpha subunit of the heterotrimeric G protein in G protein-coupled receptor (

64 A long-held tenet of heterotrimeric G protein signal transduction is that it

65 les in G protein-coupled receptor (GPCR) and heterotrimeric G protein signal transduction.

66 Heterotrimeric G protein signaling cascades are one of t

67 ne nucleotide exchange factor that activates heterotrimeric G protein signaling downstream of RTKs an

68 intermediate molecule(s) that could activate heterotrimeric G protein signaling in a calcium-dependen

69 integrin activation in platelets is through heterotrimeric G protein signaling regulating hemostasis

70 ng (RGS) domain proteins generally attenuate heterotrimeric G protein signaling, thereby fine-tune th

71 g., analgesia) are predominantly mediated by heterotrimeric G protein signaling, whereas beta-arresti

72 ts and reveal a higher level of diversity in heterotrimeric G protein signaling.

73 Galpha12/13 but not representatives of other heterotrimeric G protein subfamilies, such as Galphai1,

74 cible sequestration system to inactivate the heterotrimeric G protein subunit Gbeta and find that thi

75 these interactors, we further establish the heterotrimeric G protein subunit Gnb5 as a PSD-95 comple

76 C-beta (PLC-beta) isoforms are stimulated by heterotrimeric G protein subunits and members of the Rho

77 of the AC NT for mechanisms of regulation by heterotrimeric G protein subunits is isoform-specific.

78 atalyzing the exchange of GDP for GTP on the heterotrimeric G protein transducin (GT).

79 mma as a critical signaling component of the heterotrimeric G protein, along with the nature of presy

80 he pathway comprises a pheromone receptor, a heterotrimeric G protein, and intracellular effectors of

81 eceptors may couple to more than one type of heterotrimeric G protein, each of which consists of a Ga

82 o examine the role of Galpha13, a G12 family heterotrimeric G protein, in regulating cellular invasio

83 dissociation of the Galpha subunit from the heterotrimeric G protein, leading to downstream signalin

84 GNA13, the alpha subunit of a heterotrimeric G protein, mediates signaling through G-p

85 ere the very first genes for agonist-binding heterotrimeric G protein-coupled receptors (GPCRs) to be

86 activation of MMP14 and identify MMP14 as a heterotrimeric G protein-regulated effector.

87 Thus, our results identify a putative Wnt/heterotrimeric G protein/PI3K pathway for PCP regulation

88 ies in plant immunity provide a link between heterotrimeric G proteins and an MAPK cascade via the RA

89 o regulate major physiological processes via heterotrimeric G proteins and beta-arrestins.

90 -protein-coupled receptors (GPCRs) activates heterotrimeric G proteins and downstream signaling.

91 rs (GPCRs) and the interaction of GPCRs with heterotrimeric G proteins and effector molecules.

92 ich agonist stimulation leads to coupling of heterotrimeric G proteins and generation of second messe

93 Heterotrimeric G proteins and other regulators are impor

94 These signaling pathways are modulated by heterotrimeric G proteins and the scaffold proteins beta

95 iple waves of signaling that are mediated by heterotrimeric G proteins and the scaffolding proteins b

96 ed receptors (GPCRs) allosterically activate heterotrimeric G proteins and trigger GDP release.

97 how SMO is stimulated to form a complex with heterotrimeric G proteins and whether G-protein coupling

98 Heterotrimeric G proteins are activated by exchange of G

99 Heterotrimeric G proteins are categorized into four main

100 Heterotrimeric G proteins are crucial for the perception

101 Heterotrimeric G proteins are important molecular switch

102 Heterotrimeric G proteins are key molecular switches tha

103 The heterotrimeric G proteins are known to have a variety of

104 Heterotrimeric G proteins are localized to the plasma me

105 Heterotrimeric G proteins are molecular switches that re

106 Both small monomeric and heterotrimeric G proteins are primarily prenylated, eith

107 Heterotrimeric G proteins are quintessential signalling

108 Heterotrimeric G proteins are signal transduction protei

109 Heterotrimeric G proteins are signaling switches that co

110 Heterotrimeric G proteins are the core upstream elements

111 Heterotrimeric G proteins are usually activated by the g

112 ggers signal transduction cascades involving heterotrimeric G proteins as key players.

113 Activation of heterotrimeric G proteins by cytoplasmic nonreceptor pro

114 hes, we unravel a mechanism of activation of heterotrimeric G proteins by RTKs and chart the key step

115 Heterotrimeric G proteins communicate signals from activ

116 Heterotrimeric G proteins composed of alpha, beta, and g

117 ivates several signaling pathways, including heterotrimeric G proteins Gq and G12, as well as the ext

118 R40 is known to signal predominantly via the heterotrimeric G proteins Gq/11.

119 ed Receptors (aGPCRs) functionally couple to heterotrimeric G proteins has been emerging in increment

120 versity of functions and phenotypes in which heterotrimeric G proteins have been implicated.

121 Accordingly, XLGs expand the repertoire of heterotrimeric G proteins in plants and reveal a higher

122 receptors (GPCRs), in addition to activating heterotrimeric G proteins in the plasma membrane, appear

123 Additionally, we studied the role of heterotrimeric G proteins in Wnt-5a-dependent synaptic d

124 G-protein-coupled receptors, the activity of heterotrimeric G proteins is modulated by many cytoplasm

125 Heterotrimeric G proteins play a pivotal role in the sig

126 Heterotrimeric G proteins play an essential role in the

127 Our findings reveal that FZD9 and heterotrimeric G proteins regulate Wnt-5a signaling and

128 Heterotrimeric G proteins signal at a variety of endomem

129 f GPCR signaling that dampen the activity of heterotrimeric G proteins through their GTPase-accelerat

130 tein Signaling (RGS) promote deactivation of heterotrimeric G proteins thus controlling the magnitude

131 ceptors in the brain, and it signals through heterotrimeric G proteins to activate a variety of effec

132 s signals from the Galpha(q/11) subfamily of heterotrimeric G proteins to the small guanosine triphos

133 oupling to any of the four major subtypes of heterotrimeric G proteins was found.

134 investigated the inactive-state assembly of heterotrimeric G proteins with FZD4, a receptor importan

135 sponse through the binding and activation of heterotrimeric G proteins(2,3).

136 Gsalpha, the stimulatory subunit of heterotrimeric G proteins, activates downstream signalin

137 , (ii) binding of the Gbetagamma subunits of heterotrimeric G proteins, and (iii) phosphorylation of

138 ghly homologous alpha subunits of Galphaq/11 heterotrimeric G proteins, and in PLCB4 (phospholipase C

139 1 matrix metalloprotease (MMP14, MT1-MMP) by heterotrimeric G proteins, and in turn, the generation o

140 to promote arrestin binding, decoupling from heterotrimeric G proteins, and internalization.

141 Arrestin recruitment uncouples GPCRs from heterotrimeric G proteins, and targets the proteins for

142 cells by catalyzing nucleotide release from heterotrimeric G proteins, but the mechanism underlying

143 Heterotrimeric G proteins, consisting of Galpha, Gbeta,

144 ins, which form the alpha subunit of certain heterotrimeric G proteins, drive uveal melanoma oncogene

145 sages to signaling events by coupling to the heterotrimeric G proteins, Galpha*betagamma Classic phar

146 agonist-promoted interactions of GPCRs with heterotrimeric G proteins, GPCR kinases (GRKs), and arre

147 (GNB1) gene, encoding the Gbeta1 subunit of heterotrimeric G proteins, have recently been identified

148 Heterotrimeric G proteins, including combinations believ

149 dy, we report that GPR139 activates multiple heterotrimeric G proteins, including members of the G(q/

150 is transient (<10 minutes) and initiated by heterotrimeric G proteins, is followed by a second wave

151 hat specifically target host Rho GTPases and heterotrimeric G proteins, respectively.

152 of a similar domain in the Galpha subunit of heterotrimeric G proteins, supporting a potential role f

153 y which receptor tyrosine kinases (RTKs) and heterotrimeric G proteins, two major signaling hubs in e

154 PKA and upstream of the Galphai component of heterotrimeric G proteins, which itself localizes to cil

155 verse intracellular transducers, prominently heterotrimeric G proteins.

156 aARs) become desensitized and uncoupled from heterotrimeric G proteins.

157 ontrol bundle polarity cell-autonomously via heterotrimeric G proteins.

158 ling by receptors coupled to the Gq/11 class heterotrimeric G proteins.

159 es through Galphai2- and Galphai3-containing heterotrimeric G proteins.

160 d GNAQ, genes that encode Galpha subunits of heterotrimeric G proteins.

161 mpounds are available that directly modulate heterotrimeric G proteins.

162 cterized based on their ability to couple to heterotrimeric G proteins.

163 regulated by receptor-mediated activation of heterotrimeric G proteins.

164 for nucleotide binding studies with RAS and heterotrimeric G proteins.

165 pes together form the least studied group of heterotrimeric G proteins.

166 intracellular "transducer" proteins, such as heterotrimeric G proteins.

167 o 24(S),25-epoxycholesterol and coupled to a heterotrimeric G(i) protein.

168 tagamma-dependent Rac pathway, attributed to heterotrimeric G(i) proteins.

169 1 in complex with the agonist JMV449 and the heterotrimeric G(i1) protein, at a resolution of 3 angst

170 ts a conformation similar to that in the M2R-heterotrimeric G(o) protein complex(3).

171 capable of activating beta-arrestin but not heterotrimeric G(q) protein signaling.

172 PR52 signalling occurs primarily through the heterotrimeric G(s) protein(2), but it is unclear how GP

173 Heterotrimeric G-protein (Galpha, Gbeta and Ggamma) are

174 versatility of tools available to manipulate heterotrimeric G-protein activity.

175 T based sensor for detecting activation of a heterotrimeric G-protein by G-protein coupled receptors.

176 1 Gbeta and 3 Ggamma proteins represent the heterotrimeric G-protein complex in Arabidopsis, and a s

177 Arabidopsis heterotrimeric G-protein complex modulates pathogen-asso

178 B2 encodes the beta2 subunit (Gbeta2) of the heterotrimeric G-protein complex that is being released

179 for the signaling processes mediated by the heterotrimeric G-protein complex.

180 Signaling pathways mediated by heterotrimeric G-protein complexes comprising Galpha, Gb

181 ng the Galpha, Gbeta, and Ggamma subunits of heterotrimeric G-protein complexes, which function upstr

182 e therefore diagnoses in the group of mosaic heterotrimeric G-protein disorders, joining McCune-Albri

183 This response involves the heterotrimeric G-protein EGL-30//G(alphaq) acting in mot

184 he histamine receptor subtypes for different heterotrimeric G-protein families with single-cell resol

185 -Ras and the inhibitory alpha-subunit of the heterotrimeric G-protein Galphai showed expected functio

186 t chemoattractants rely on activation of the heterotrimeric G-protein Galphai to regulate directional

187 opic glutamate receptor mGluR6 activates the heterotrimeric G-protein Galphaobeta3gamma13, and this l

188 nd by targeted confirmation of a role of the heterotrimeric G-protein gamma subunit, AGG3, in cold to

189 ortholog [APPL (APP-Like)] directly bind the heterotrimeric G-protein Goalpha, supporting the model t

190 y physiological process is the activation of heterotrimeric G-protein Gs by beta(1)-ARs, leading to i

191 oxygen species, cytosolic Ca2+ (Ca2+c), and heterotrimeric G-protein signaling.

192 city, in which it is functionally coupled to heterotrimeric G-protein signaling.

193 s) recruit beta-arrestin, which desensitizes heterotrimeric G-protein signalling and promotes recepto

194 PAR1 is promiscuous and couples to multiple heterotrimeric G-protein subtypes in the same cell and p

195 d receptor called V2R, which signals through heterotrimeric G-protein subunit G(s) alpha, adenylyl cy

196 Putative functions of the heterotrimeric G-protein subunit Galphai2-dependent sign

197 es, Ras, Rab, and the G(alphai) subunit of a heterotrimeric G-protein, both in the presence and in th

198 gand histamine by activating three canonical heterotrimeric G-protein-mediated signaling pathways wit

199 moting neurons, and likely couples to a Gi/o heterotrimeric G-protein.

200 Heterotrimeric G-proteins (comprising Galpha and Gbetaga

201 GPCRs) relay extracellular signals mainly to heterotrimeric G-proteins (Galphabetagamma) and they are

202 Heterotrimeric G-proteins (Galphabetagamma) are the main

203 proteins that bind the betagamma subunits of heterotrimeric G-proteins (Gbetagamma).

204 r that couples to the Galpha(i) subfamily of heterotrimeric G-proteins and beta-arrestins (betaarrs)

205 Heterotrimeric G-proteins are essential cellular signal

206 Heterotrimeric G-proteins are implicated in several plan

207 Heterotrimeric G-proteins are key modulators of multiple

208 lpha subunits of any of the four families of heterotrimeric G-proteins are putative cancer drivers.

209 Heterotrimeric G-proteins are signal transducers involve

210 Heterotrimeric G-proteins are signaling switches broadly

211 calcium concentration ([Ca(2+) ](cyt) ) and heterotrimeric G-proteins are universal eukaryotic signa

212 Heterotrimeric G-proteins comprised of Galpha, Gbeta and

213 One such network involves heterotrimeric G-proteins comprised of Galpha, Gbeta, an

214 Signaling pathways regulated by heterotrimeric G-proteins exist in all eukaryotes.

215 we report the functional characterization of heterotrimeric G-proteins from a nonvascular plant, the

216 The basic schemes of heterotrimeric G-proteins have been outlined.

217 s (Rac1, RhoA/B/C, and Cdc42) as well as for heterotrimeric G-proteins in a series of live-cell imagi

218 Heterotrimeric G-proteins influence almost all aspects o

219 te biosensors with specificity for different heterotrimeric G-proteins or for other G-proteins, such

220 s to a group of unconventional activators of heterotrimeric G-proteins that are cytoplasmic factors r

221 GPCRs activate heterotrimeric G-proteins that stimulate intracellular c

222 odular protein that allows the activation of heterotrimeric G-proteins with blue light.

223 Heterotrimeric G-proteins, comprising Galpha, Gbeta, and

224 cruited to the cortex by Galphai-subunits of heterotrimeric G-proteins.

225 into the cell via coupling to intra-cellular heterotrimeric G-proteins.

226 d free Gbetagamma: the two active species of heterotrimeric G-proteins.

227 GPCRs signal via the canonical heterotrimeric Galpha and Gbetagamma subunits.

228 ucing signals from the microenvironment, and heterotrimeric Galpha signaling links these receptors to

229 (GPCRs) promote nuclear F-actin assembly via heterotrimeric Galpha(q) proteins.

230 AQ and GNA11, which encode alpha subunits of heterotrimeric Galpha(q/11) proteins, occur in about 85%

231 Opioid receptors couple to various heterotrimeric Galphabetagamma proteins to convert extra

232 Both of these require heterotrimeric Galphai protein signaling, whose intensit

233 receptor, in complex with peptide ligand and heterotrimeric Galphasbetagamma protein determined by Vo

234 Here, we report that the sole Arabidopsis heterotrimeric Gbeta subunit, AGB1, is required for four

235 activity are regulated via interactions with heterotrimeric Gbetagamma subunits, PIP(3), and protein

236 e state of human kappaOR complexed with both heterotrimeric Gi protein and MP1104 agonist.

237 ght-sensitive GPCR rhodopsin in complex with heterotrimeric Gi.

238 show that activation of receptors coupled to heterotrimeric Gi/o proteins inhibits TRPM3 channels.

239 sine monophosphate stimulation, highlights a heterotrimeric GTP-binding protein (G protein)-independe

240 he transmembrane region, couple to different heterotrimeric GTP-binding proteins (G proteins) to tran

241 lpha7 nAChRs bind signaling proteins such as heterotrimeric GTP-binding proteins (G proteins).

242 GNB5 encodes an atypical beta subunit of the heterotrimeric GTP-binding proteins (Gbeta5).

243 Heterotrimeric GTP-binding proteins are key regulators o

244 translation initiation factor 2 (eIF2) is a heterotrimeric GTPase, which plays a critical role in pr

245 Family B heterotrimeric guanine nucleotide-binding protein (G pro

246 Heterotrimeric guanine nucleotide-binding proteins (G pr

247 its, binds to MOR, and inhibits signaling to heterotrimeric guanine nucleotide-binding proteins (G pr

248 Heterotrimeric guanine-nucleotide-binding regulatory pro

249 B/R2, B'/R5, and B"/R3), which form the PP2A heterotrimeric holoenzyme by associating with a dimer co

250 which are transcribed and replicated by the heterotrimeric IAV RNA-dependent RNA-polymerase (RdRp).

251 channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extrac

252 ASIC proteins can form both homotrimeric and heterotrimeric ion channels.

253 7, osmotic avoidance abnormal-3 (OSM-3)] and heterotrimeric (KIF3) kinesin-2 motors are required to e

254 Loss of function in any subunit of the heterotrimeric KIF3A/KIF3B/KAP kinesin-2 motor prevents

255 Homodimeric KIF17 and heterotrimeric KIF3AB are processive, kinesin-2 family m

256 The heterotrimeric kinase AMPK acts as an energy sensor to c

257 ecular determinants mediating trafficking of heterotrimeric kinesin-2 itself are poorly understood.

258 Mammalian KIF3AC is classified as a heterotrimeric kinesin-2 that is best known for organell

259 The heterotrimeric kinesin-2, consisting of the heterodimeri

260 for shorter run lengths observed for another heterotrimeric kinesin-2, KIF3AB.

261 strate unexpected new roles for both ciliary heterotrimeric kinesins and IFT particle genes and clari

262 f bacteria is mediated by a highly conserved heterotrimeric membrane protein complex denoted Sec61 in

263 to a protein-conducting channel formed by a heterotrimeric membrane protein complex, the prokaryotic

264 Intracellularly, heterotrimeric molecules associate to form dimers and te

265 The mammalian kinesin-2, KIF3A/B, is a heterotrimeric motor involved in intraflagellar transpor

266 t and activation of Tel1(ATM) depends on the heterotrimeric MRX(MRN) complex, composed of Mre11, Rad5

267 Because of the heterotrimeric nature of the PCNA clamp in some archaea,

268 d on studies of two prototypical models, the heterotrimeric pili in Corynebacterium diphtheriae and t

269 tes in the cell nucleus and assembles into a heterotrimeric polymerase with PB1 and PA.

270 ells by allosterically assembling a specific heterotrimeric PP2A holoenzyme consisting of PPP2R1A (sc

271 contributing to the formation of an unusual heterotrimeric PPC decarboxylase (PPCDC) complex crucial

272 is superior in predicting heterodimeric and heterotrimeric protein assemblies.

273 mma of eukaryotes is a universally conserved heterotrimeric protein channel complex that accommodates

274 s in many organisms secrete laminin, a large heterotrimeric protein consisting of an alpha, beta, and

275 Collagen VI is a ubiquitous heterotrimeric protein of the extracellular matrix (ECM)

276 The conserved heterotrimeric protein phosphatase PP2A controls the tim

277 LE: AMPK (AMP-activated protein kinase) is a heterotrimeric protein that plays an important role in e

278 Laminin, an approximately 800-kDa heterotrimeric protein, is a major functional component

279 representative of its structure in the viral heterotrimeric protein.

280 s through its recruitment to a high-affinity heterotrimeric receptor complex (IL-2Ralpha/IL-2Rbeta/ga

281 ial signals for immunity, operates through a heterotrimeric receptor.

282 Their heterotrimeric receptors share their beta- and gamma(c)-

283 mere DNA-binding protein Teb1, paralogous to heterotrimeric replication protein A (RPA).

284 t is transcribed and replicated by the viral heterotrimeric RNA polymerase (FluPol) in the context of

285 The PB2 subunit of the viral heterotrimeric RNA polymerase binds the cap structure of

286 hemical fluorophore onto a single subunit of heterotrimeric RPA.

287 dynamic polypeptide-conducting channel, the heterotrimeric Sec61 complex.

288 annel SecYEG, the motor ATPase SecA, and the heterotrimeric SecDFyajC membrane protein complex.

289 The heterotrimeric SecY translocon complex is required for t

290 AMP kinase is a heterotrimeric serine/threonine protein kinase that regu

291 was expressed as individual subunits or as a heterotrimeric single-chain SPT fusion protein.

292 cation protein A (RPA) is a highly conserved heterotrimeric single-stranded DNA-binding protein invol

293 nal ensemble of the alpha subunit Galphas of heterotrimeric stimulatory protein Gs exhibits structura

294 heds light on the process whereby an ancient heterotrimeric TF mainly controlling cell division in an

295 Here we describe a heterotrimeric TFIID subcomplex consisting of the TAF2,

296 ere we show that it is possible to form pure heterotrimeric three-stranded coiled coils by combining

297 A heterotrimeric transcription factor NF-Y is crucial for

298 Nuclear Factor Y (NF-Y) is a heterotrimeric transcription factor that binds CCAAT ele

299 In this context, heterotrimeric viral PA/PB1/PB2 RNA-dependent RNA polyme

300 Mutants of the heterotrimeric viral polymerase components, particularly