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1 ositive feedback loop involving IL-2 and its high affinity receptor.
2 expressing a neurotrophin and its associated high-affinity receptor.
3 response requires the binding of IgE to its high-affinity receptor.
4 anisms of interaction between GM-CSF and its high-affinity receptor.
5 actions of neurotensin are mediated via its high-affinity receptor.
6 t complexes with the alpha subunit to form a high-affinity receptor.
7 ic mucosa against CWR-induced injury via its high-affinity receptor.
8 and in the presentation of growth factors to high affinity receptors.
9 of its mitogenic activity and its binding to high affinity receptors.
10 levels correlated with a larger fraction of high-affinity receptors.
11 st explained by a local spillover activating high-affinity receptors.
12 d selective clonal expansion of B cells with high-affinity receptors.
13 ents of these two neurotrophins and/or their high-affinity receptors along the tonotopic map, and the
14 bond abrogated cooperativity, resulting in a high affinity receptor and increased sensitivity of down
15 ods to understand why it is hard to design a high-affinity receptor and to explore the limits of affi
17 This increased KAR function was mediated by high-affinity receptors and required activation of NMDA
19 via interactions between substance P and its high affinity receptor, as evidenced by the absence of a
20 han a single Neu5Ac, appears to serve as the high-affinity receptor, as typhoid toxin possesses five
21 presence of CP105696, an antagonist for LTB4 high-affinity receptor, ATP was not able to reduce paras
31 ce is investigated using as a model an ultra-high-affinity receptor binding variant of human growth h
34 for leukotriene B4 have been identified: the high-affinity receptor BLT1 and the low-affinity recepto
37 (GABAA-Rs), or via continuous activation of high-affinity receptors by low concentrations of ambient
38 s with viruses that infect through different high-affinity receptors (CAR, CD46, and desmoglein-2), a
39 d with decreased expression of interleukin-2 high-affinity receptors (CD25), STAT3 signaling, and cel
40 emoattractant protein (MCP)-1 (CCL2) and its high-affinity receptor, chemokine (C-C motif) receptor 2
44 12 is mediated through specific binding to a high affinity receptor complex composed of at least two
45 L-4 receptor alpha (IL-4Ralpha), a signaling high affinity receptor complex for IL-13 is generated.
46 T cells, IL-2 signals through a quaternary 'high affinity' receptor complex consisting of IL-2, IL-2
48 is surface does not participate in essential high affinity receptor contacts, a finding inconsistent
52 re to 10(-7) M fMLP, which saturates the PMN high-affinity receptor, did not elicit bactericidal rele
53 Further, the increase in the fraction of high-affinity receptors due to the presence of ErbB2 occ
54 ytes, and the vessel wall and interacts with high affinity receptors expressed in several tissues inc
55 affinity receptor families (GluK1-GluK3) and high-affinity receptor families (GluK4-GluK5) based on t
56 Fc epsilon 3-4) to a soluble fragment of the high-affinity receptor Fc epsilon RI alpha-chain (sFc ep
62 teraction between IgE-Fc (Fcepsilon) and its high affinity receptor FcepsilonRI on the surface of mas
64 emarkably stable interaction of IgE with its high-affinity receptor FcepsilonRI on basophils and mast
66 functional IgG autoantibodies to IgE or its high-affinity receptor (FcepsilonRI) induces mast cell d
71 cal blockade of ligand signaling through the high affinity receptor for activin, type II activin rece
72 esults demonstrate that beta2-chimaerin is a high affinity receptor for DAG through binding to its C1
76 he cell surface-expressed gamma chain of the high affinity receptor for IgE (FcepsilonRI) can be phos
81 fibroblasts previously transfected with the high affinity receptor for IgE (FcepsilonRI) were furthe
82 receptor that responds to aggregation is the high affinity receptor for IgE (FcepsilonRI), which is r
84 elta with Lyn required the activation of the high affinity receptor for IgE (FcsigmaRI) while the int
86 s-linking of IgE bound to mast cells via the high affinity receptor for IgE triggers a signaling casc
88 inhibit binding of IgE to both CD23 and the high affinity receptor for IgE, Fc epsilonRI, providing
94 We have recently described an additional high affinity receptor for IL-13, IL-13Ralpha2, whose fu
97 reflecting a low level of expression of the high affinity receptor for IL-7 (CD127) relative to conv
98 WIP in signaling pathways downstream of the high affinity receptor for immunoglobulin (Ig)E (Fcepsil
105 and its closely related homologue GPR4 is a high affinity receptor for SPC with low affinity for lys
106 -coupled receptor 1 (OGR1) as a specific and high affinity receptor for SPC, and G2A as a receptor wi
107 cer G protein-coupled receptor 1 (OGR1) is a high affinity receptor for SPC, and its closely related
108 we have identified GPR4 as not only another high affinity receptor for SPC, but also a receptor for
109 ceptor from vascular endothelial cells, is a high affinity receptor for sphingosine 1-phosphate (SPP)
111 us, 12-HETER represents the first identified high affinity receptor for the 12-(S)-HETE hydroxyl fatt
112 The TrkB receptor tyrosine kinase (RTK) is a high affinity receptor for the neurotrophins brain deriv
115 ; in contrast, BCMA and BR3, the other known high affinity receptors for APRIL and BAFF, respectively
116 parations show that B104 cells expressed the high affinity receptors for bFGF, PDGF-AA and PDGF-BB.
118 have recently demonstrated the expression of high affinity receptors for SP (Neurokinin-1 (NK-1) rece
121 ptor-1 (VEGFR-1) and VEGFR-2 are known to be high affinity receptors for VEGF, it is not clear which
124 the discovery of cellular prion protein as a high-affinity receptor for Abeta oligomers, and the down
126 and adenovirus receptor (CAR) is not only a high-affinity receptor for adenovirus, but also a tumor
128 level of expression of full-length TrkB, the high-affinity receptor for BDNF, despite the fact that t
129 n demonstrate that the presence of TrkB, the high-affinity receptor for BDNF, in hippocampal neural p
130 ific ablation of TrkB, the gene encoding the high-affinity receptor for BDNF, is sufficient to elicit
133 triene B(4) receptor, was also shown to be a high-affinity receptor for cyclooxygenase-1 derived 12(S
136 , and (iii) ErbB4 is a candidate for being a high-affinity receptor for HB-EGF on the surface of impl
139 circulating IgE, increased expression of the high-affinity receptor for IgE (Fc epsilonRI), and great
140 s (MC) and basophils share expression of the high-affinity receptor for IgE (FcepsilonRI) but can be
145 idermal Langerhans cells (LC) expressing the high-affinity receptor for IgE (FcepsilonRI) play a key
146 and T cells and for Fc receptors such as the high-affinity receptor for IgE (FcepsilonRI), a Src fami
149 scribe key MC governance mechanisms (ie, the high-affinity receptor for IgE [FcepsilonRI]), the stem
150 re activated through receptors including the high-affinity receptor for IgE and KIT, specific tyrosin
151 mmation by virtue of their expression of the high-affinity receptor for IgE and release of potent pro
154 tients with atopic dermatitis (AD) carry the high-affinity receptor for IgE, FcepsilonRI, and are cru
156 to FcepsilonRIalpha, the alpha-chain of the high-affinity receptor for IgE, has been identified.
157 imulation of mast cells via FcepsilonRI, the high-affinity receptor for IgE, triggers a signaling cas
159 pregulation of interleukin (IL)-13Ralpha2, a high-affinity receptor for IL-13 that regulates tumor gr
160 risingly, we now find that expression of the high-affinity receptor for IL-15, IL-15R alpha, on T cel
162 e response initiated by cross-linking of the high-affinity receptor for immunoglobulin E (FcepsilonRI
164 e stimulated following the activation of the high-affinity receptor for immunoglobulin E (IgE) in mas
166 nd protein levels on stimulation through the high-affinity receptor for immunoglobulin E (IgE; Fcepsi
167 ctions are triggered via crosslinking of the high-affinity receptor for immunoglobulin E, F(c)epsilon
168 ated mast cell degranulation mediated by the high-affinity receptor for immunoglobulin E, FcepsilonRI
169 d-mediated cross-linking of FcepsilonRI, the high-affinity receptor for immunoglobulin E, on RBL-2H3
171 The 29-kDa nuclear protein is likely the high-affinity receptor for JH that mediates its genomic
173 mutant was related to expression of CD14, a high-affinity receptor for LPS and other microbial produ
177 genetic ablation of Acvr2b, which encodes a high-affinity receptor for myostatin and activin A speci
179 he NTRK1 gene (also known as TRKA) encodes a high-affinity receptor for NGF, a neurotrophin involved
183 sulin resistance, we studied the role of the high-affinity receptor for RBP4, STRA6 (stimulated by re
184 Here, we report that neuropilin (NRP)-2, the high-affinity receptor for SEMA3F and a coreceptor for c
186 her Robo receptors, mammalian Robo3 is not a high-affinity receptor for Slits because of specific sub
187 erived G-protein-coupled receptor EDG-1 is a high-affinity receptor for the bioactive lipid mediator
188 Protease-activated receptor-1 (PAR-1) is the high-affinity receptor for the coagulation protease thro
190 The receptor tyrosine kinase c-MET is the high-affinity receptor for the hepatocyte growth factor
191 Protein kinase C (PKC) represents the major, high-affinity receptor for the phorbol esters as well as
193 press protease-activated receptor (PAR)-1, a high-affinity receptor for thrombin, which is also activ
195 VEGF receptor-1 (VEGFR-1 or Flt-1) is a high-affinity receptor for VEGF and is typically conside
198 n of coagulation by (1) expressing specific, high-affinity receptors for coagulation proteases, zymog
199 ploit molecular diversity for PK-C and other high-affinity receptors for DAG and the phorbol esters.
202 cell degranulation induced by aggregation of high-affinity receptors for IgE (FcepsilonRI) is negativ
203 C) activation via cross-linking of IgE-bound high-affinity receptors for IgE (FcepsilonRI) underlies
205 y mast cells (MCs) on cross-linking of their high-affinity receptors for IgE by antigen that can ampl
207 al in the human host and therefore expresses high-affinity receptors for iron acquisition from host i
212 demonstrated that resident CNS cells express high-affinity receptors for this neuropeptide (neurokini
215 onclude that recombinant hA(2A)AR can form a high-affinity receptor-G protein complex with alpha(s)be
217 The disruption of the human immunolobulin E-high affinity receptor I (IgE-FcepsilonRI) protein-prote
218 s in layer V colabeled with their respective high-affinity receptors, i.e., trkA, trkB, and trkC, res
219 t IFN-gamma SC1 forms a 1:1 complex with its high-affinity receptor (IFN-gamma R alpha) with an affin
225 calize the diTC binding site and to design a high affinity receptor in the diTC-insensitive channel,
226 does not bind GM-CSF by itself, but forms a high-affinity receptor in association with GMRalpha.
227 rovides evidence for the role of NGF and its high-affinity receptor in the pathogenesis of psoriasis
229 s, alpha and beta, and ligand binding to the high-affinity receptor leads to signalling for the multi
230 for a detailed thermodynamic description of high-affinity receptor-ligand interactions involving poo
232 and the group of alleles encoding A19), the high-affinity receptor/ligand pair KIR2DL2/HLA-C1, and t
233 armacophore features usually associated with high-affinity receptor ligands such as the heteroatom hy
235 binding of soluble HLA-G to its alternative high-affinity receptor, LILRB1 (ILT2), appeared to be le
236 kotriene B(4) (LTB(4)), interacting with its high-affinity receptor, LTB(4) receptor 1 (BLT1), is kno
238 eurons (SGNs) in the inner ear; however, its high affinity receptor, neurokinin-1 (NK1), has not been
240 ion and cell proliferation by binding of its high affinity receptor, neurotensin receptor-1 (NTR1).
241 function and also induce an elevation in the high affinity receptor, nicotinic therapy in autism may
243 of the neuropeptide neurotensin (NT) and its high affinity receptor (NTR1) is increased during the co
244 led that VEGF induced a 2-3-fold increase in high affinity receptor number (5.0 x 10(4)/cell versus 2
246 rotein (LIVBP or LivJ) serves as the primary high-affinity receptor of the Escherichia coli ABC-type
248 gen-mediated aggregation of IgE bound to its high-affinity receptor on mast cells or basophils initia
251 ted that alpha-latrotoxin first binds to two high-affinity receptors on nerve terminals, neurexins an
252 mediates its biologic activities via binding high-affinity receptors on T and natural killer cells.
253 teracts with the blastocyst cell surface via high-affinity receptors other than ErbB1, (ii) the HB-EG
254 ochromocytoma clone (PC12) by activating the high affinity receptor, p140(trkA), linked to mitogen-ac
255 se-activating peptide (PACAP) and one of its high-affinity receptors (PAC1) are widely expressed in t
259 proteins have been described as the low- and high-affinity receptors, respectively, for the cytotoxic
260 s in collagen gel assays through a conserved high-affinity receptor, Ryk, which is expressed in CST a
261 of the pore, contribute to formation of the high-affinity receptor site for pore-blocking drugs, and
262 potentially cytolytic protein that is also a high-affinity receptor site specific antagonist for the
265 eceptor binding the agonist epibatidine (the high affinity receptor subtype, consisting primarily of
266 g Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling ma
267 uggested that colicin N (ColN), which has no high-affinity receptor, targets highly abundant lipopoly
268 late the transcription of numerous genes via high affinity receptors that act in concert with chromat
269 More recently, human folate receptors (FRs), high affinity receptors that transport folate via endocy
270 ock the binding of IL-2 to IL-2Ralpha of the high affinity receptor, the 7G7/B6 monoclonal antibody b
273 plementation of H BiC (H-BiC) reveals that a high-affinity receptor-to-paramyxovirus H monomer stoich
274 ing of nerve growth factor (NGF) through its high-affinity receptor TrkA contributes to attention beh
275 shing a role for nerve growth factor and its high-affinity receptor TrkA in contextual memory consoli
276 position where nerve growth factor binds its high affinity receptor, TrkA, suggesting further paralle
281 be mediated through interactions with their high-affinity receptors TrkB (for BDNF and NT-4/5) and T
282 erived neurotrophic factor (BDNF) and of its high affinity receptor (trkB) mRNA was investigated in t
286 urotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (Tr
287 n-derived neurotrophic factor (BDNF) and its high-affinity receptor tropomyosin-related kinase B (trk
288 ous mutations of either human NGFbeta or its high-affinity receptor tropomyosin-related kinase recept
289 n-derived neurotrophic factor (BDNF) and its high affinity receptor, tropomyosin receptor kinase B (T
290 urotrophin family of growth factors, and its high-affinity receptor, tropomyosin receptor kinase B (T
291 d neurotrophin-3 (NT-3) and their respective high-affinity receptors, tropomyosin receptor kinase (tr
293 rotrophins in vitro by transactivating their high-affinity receptor tyrosine kinases, the Trk recepto
295 nase-type plasminogen activator (uPA) to its high-affinity receptor (uPAR) orchestrates uPAR interact
296 entified desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad
297 lar endothelial growth factor (VEGF) and its high-affinity receptors VEGFR-1 and VEGFR-2 was investig
298 products for the full-length Trk A and Trk C high-affinity receptor were observed, as well as truncat
299 ted that Klotho proteins function as primary high-affinity receptors while FGFRs function as the cata