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1 nalyzed: 141 (89%) low grade versus 17 (11%) high grade.
2 than 5 cm in diameter and of intermediate or high grade.
4 ian laser pulsations delivered (low=0 versus high grade=5852, P<0.001) were significantly higher in h
5 ients with cerebral gliomas (9 low-grade, 34 high-grade; 9 primary tumors, 34 recurrent tumors) who h
9 oxicity tables that include the incidence of high-grade adverse events, defined by the Common Termino
12 of human papillomavirus (HPV) genotypes-and high-grade anal intraepithelial neoplasia (HGAIN) in men
13 a11/PDGFRbeta expression was associated with high grades and poorer clinical outcome in human BC pati
16 e molecular drivers of invasive progression, high-grade and metastatic disease are poorly defined.
18 vels) in well characterized cohorts of human high-grade astrocytomas, mostly glioblastomas, compared
19 ogical and optical mapping studies indicated high-grade atrioventricular (A-V) block in ZO-1cKO compa
22 shock, sustained ventricular arrhythmia, and high-grade atrioventricular block within 30 days includi
23 e that can also efficiently bind B cells and high-grade B cell lymphoma (diffuse large B cell lymphom
24 d (NOS); 20 LBCL-IRF4 cases; and 12 cases of high-grade B-cell lymphoma (HGBCL), NOS in patients <=25
26 oups included diffuse large B-cell lymphoma, high-grade B-cell lymphoma with rearrangements of MYC an
29 n, it is an emerging precursor to neoplastic high-grade B-cell lymphoproliferation among people with
30 r, the ApoA1 concentrations of patients with high-grade BC were significantly higher than those of pa
32 iography (3.4% versus 10.2%, P<0.0001), have high-grade CAD (0.5% versus 6.5%, P<0.0001), and receive
34 identifies PET/CT patients unlikely to have high-grade CAD or require revascularization within 90 da
35 on the percentage of (Gleason pattern-based) high-grade cancers (PHG) is demonstrated in EAs (p < 0.0
36 76% of the low-grade cancers and 71% of the high-grade cancers according to the consensus reading.
39 iency virus (HIV) plasma viral load (PVL) on high-grade cervical intraepithelial neoplasia (CIN2+) de
42 al effectiveness of qHPV vaccination against high-grade cervical precancerous lesions, among women va
44 as the presence of residual and/or recurrent high-grade CIN2+/high-grade squamous intraepithelial les
46 tic intraepithelial lesion (n = 18, 38%) and high-grade conjunctival melanocytic intraepithelial lesi
47 graphy (PET/CT), is often used to assess for high-grade coronary artery disease (CAD) requiring revas
50 those with low-grade disease may progress to high-grade disease after immune modulation, which can be
52 ve immune surveillance of EBV, patients with high-grade disease may have a recurrence in the form of
54 mmune-dependent and typically polyclonal and high-grade disease to be immune-independent and typicall
55 ts with cN0 early breast cancer or extensive/high-grade ductal carcinoma in situ planned for standard
56 nce of UDD in predicting advanced neoplasia [high grade dysplasia or invasive carcinoma (HGD/IC)] was
57 of recurrent colonic adenoma associated with high-grade dysplasia (HGD) colon polyps at baseline colo
58 ty (HR 4.53, 95%CI 1.34-15.26; P = 0.02) and high-grade dysplasia (HGD) in the original resection (HR
59 BE patients at high risk for progression to high-grade dysplasia (HGD) or EAC are needed to improve
60 d 54 BE samples collected from patients with high-grade dysplasia (HGD) or esophageal adenocarcinoma
61 esection (ER) and ablation for patients with high-grade dysplasia (HGD) or intramucosal adenocarcinom
63 ssification based on adenoma size >=20 mm or high-grade dysplasia (instead of the current high-risk c
64 ratio [SIR] 2.07; 95% CI 1.40-2.93) or with high-grade dysplasia (SIR 0.79; 95% CI 0.39-1.41), where
65 ression in plasma EV of the 11 patients with high-grade dysplasia alone, only 1 had high MUC5AC expre
66 were 1.09 (95% CI, 0.85-1.33) for low-grade/high-grade dysplasia and 0.14 (95% CI, 0.06-0.22) for GC
68 ntraductal papillary mucinous neoplasms with high-grade dysplasia and some enlarged pancreatic intrae
69 excision of advanced adenomas, diagnosis of high-grade dysplasia in the rectum or pouch, or progress
70 cholangitis) and no history of advanced CRN (high-grade dysplasia or colorectal cancer) or colectomy.
71 tion rates of lesions suspected of harboring high-grade dysplasia or early adenocarcinoma, a novel gr
72 a, with any or low-grade dysplasia, and with high-grade dysplasia were 60.8 years, 65.6 years, and 70
73 t adenomas, adenomas >=20 mm in diameter and high-grade dysplasia were associated with increased risk
74 omas (<1cm, and without villous histology or high-grade dysplasia) and no neoplasia, respectively (lo
77 mpared the development of pancreatic cancer, high-grade dysplasia, or clinically worrisome features,
78 s >=10mm, adenomas with villous histology or high-grade dysplasia, or colorectal cancer [CRC]) and as
80 e cumulative incidence of pancreatic cancer, high-grade dysplasia, or worrisome features on pancreati
82 e with non-neoplastic disease and those with high-grade dysplasia/cancer with 72.1% of cases correctl
84 ed detection rate of 100% (8/8) in detecting high-grade dysplasias and carcinomas over white-light de
86 onal inactivation as a critical component of high-grade endometrial carcinoma disease pathogenesis.
89 1 week history of diffuse abdominal pain and high grade fever, associated with vomiting and frequent
90 differentiate low-grade (Fuhrman I-II) from high-grade (Fuhrman III-IV) renal cell carcinoma using r
92 low-grade glioma (n = 93), ependymoma (32), high-grade glioma (25), medulloblastoma (22), gangliogli
93 (rCBV) and VSI(MRI) in eleven patients with high-grade glioma (7 WHO grade III and 4 WHO grade IV).
94 me, phosphoproteome and transcriptome in two high-grade glioma (HGG) mouse models driven by mutated R
98 ed metric maps derived from rs-fMRI) from 68 high-grade glioma patients with different survival time.
99 data from healthy fetal tissue and pediatric high-grade glioma patients, illustrates the potential of
103 group developed response criteria for adult high-grade glioma, but these were not created to meet th
104 recommendations for the management of adult high-grade glioma, for paediatrics there is inclusion of
111 treatment resistance rates, particularly for high grade gliomas, there is a need for specific biomark
114 nant rhabdoid tumors (n = 229) and pediatric high-grade gliomas (n = 401), we show significant associ
115 metastatic cancers, including low-grade and high-grade gliomas and brain metastases (BrMs) originati
122 present the molecular landscape of low- and high-grade gliomas in patients affected by NF1 (NF1-glio
125 thods In this prospective study, adults with high-grade gliomas were enrolled between July 2015 and J
127 MRI accurately reflect vessel caliber within high-grade gliomas, while traditional measures of rCBV a
133 d response rate and 95% CIs of all-grade and high-grade (>=3) adverse effects and evaluated the withi
138 recipients receiving valganciclovir as PET, high-grade HHV-6 viremia was associated with increased a
139 survival among children and adolescents with high-grade, high-risk, mature B-cell non-Hodgkin's lymph
140 ll grades (low-grade, HR 0.38, P = 0.002 and high-grade, HR 0.62, P = 0.025) CONCLUSION:: PTR in GI-N
144 (WGS) and viral capture-based sequencing on high-grade immunohistochemically TAg-positive UCs in two
148 lue in distinction between the low-grade and high-grade intraepithelial melanocytic proliferations an
150 Family history of pancreatic cancer and high-grade IPMN was identified as risk factors for recur
151 greement in distinction between the low- and high-grade lesions was 76% for PAM, 67% for conjunctival
155 h external beam radiotherapy (EBRT), whereas high-grade lymphomas (DLBCL and MCL) were treated with c
156 he newly phenotyped mutation C480F conferred high-grade maribavir resistance and low-grade ganciclovi
157 on its efficacy and safety in children with high-grade, mature B-cell non-Hodgkin's lymphoma are lim
158 ble model, the parameters most predictive of high-grade melanocytic intraepithelial lesion/melanoma i
161 (1) >=3 s electrical pause or asystole; (2) high-grade Mobitz type II atrioventricular block or comp
164 e of the following five histologic subtypes: high-grade myxoid liposarcoma (HG-MLPS); leiomyosarcoma
167 tissue sarcoma in children and represents a high-grade neoplasm of skeletal myoblast-like cells.
168 sults in a heterogeneous spectrum of low- to high-grade neoplasms occurring during the entire lifespa
169 ied patients with EGFR-mutant SCLC and other high-grade neuroendocrine carcinomas seen at our eight i
172 e biopsy revealed a cytokeratin 20-positive, high-grade neuroendocrine neoplasm consistent with Merke
176 using 1,647 patients with resected localized high-grade or locally advanced disease (>= pT1b grade 3
178 intermediate (non-metastatic R0 or R1 >5 cm high-grade, or unresected tumour of any size or grade);
179 ma Study Group database with primary central high-grade osteosarcoma of the extremities, treated betw
181 pancreatic cancer involves visualisation of high-grade pancreatic intraepithelial neoplasias (PanIN-
182 pancreatic cancer involves visualization of high-grade pancreatic intraepithelial neoplasias (PanIN-
183 ti-gammaH2AX-TAT localizes preferentially in high-grade PanIN lesions but not in established PDAC.
184 reata, gammaH2AX expression was increased in high-grade PanINs but not in PDAC, corroborating earlier
185 reata, gammaH2AX expression was increased in high-grade PanINs, but not in PDAC, corroborating earlie
189 that SOX9 is significantly overexpressed in high-grade PC tumors (P < 0.05) and in chemotherapy-trea
190 ted mutant p53-R270H to induce carcinoma and high grade pleomorphic sarcoma in FDXR(+/-); p53(R270H/-
191 heckpoints and suppressive interleukins from high-grade pre-invasive lesions; and, ultimately, (4) th
193 weeks, Frmd6/Pten double knockouts presented high-grade prostatic intraepithelial neoplasia (HG-PIN)
194 IDC-P could further be differentiated from high-grade prostatic intraepithelial neoplasia (HGPIN),
195 compound mice developed an earlier onset of high-grade prostatic intraepithelial neoplasia and accel
196 ereas age-matched Pten littermates developed high-grade prostatic intraepithelial neoplasia and prost
197 land is frequently and densely methylated in high-grade prostatic intraepithelial neoplasia, primary
199 competence and short experimental times with high-grade read-outs when compared to conventional anima
202 he management of urinary extravasation after high-grade renal trauma, large, multi-institutional pros
205 weeks after priming with a diverse Ag pool, high-grade sepsis was induced in C57BL/6j mice that was
208 and proliferation to predict the response of high grade serous ovarian cancer (HGSOC) to neoadjuvant
211 n adult patients (>=18 years) with relapsed, high-grade serous (grade 2 or 3) epithelial ovarian, fal
216 The prevailing paradigm in the genesis of high-grade serous carcinoma (HGSC), the most common ovar
218 roprotein convertase, is highly expressed in high-grade serous carcinoma of ovarian cancer patients,
222 hich the cell lines were derived, given that high-grade serous carcinomas typically expand and spread
224 first-line, platinum-based chemotherapy with high-grade serous or endometrioid EOC should be offered
225 8 years or older who had platinum-sensitive, high-grade serous or endometrioid ovarian, primary perit
226 years or older with measurable or evaluable high-grade serous or endometrioid platinum-sensitive rec
227 18 years) with recurrent, platinum-resistant high-grade serous ovarian cancer (determined histologica
228 ) frequently develops in women with advanced high-grade serous ovarian cancer (HGSOC) and is associat
229 sought to identify susceptibility genes for high-grade serous ovarian cancer (HGSOC) by performing a
230 roteins that are differentially expressed in high-grade serous ovarian cancer (HGSOC) cell lines comp
232 case-control study of advanced and recurrent high-grade serous ovarian cancer (HGSOC) patients in whi
233 nd during neoadjuvant chemotherapy (NACT) in high-grade serous ovarian cancer (HGSOC), we performed i
235 se heritability (h(g)(2)) of EOC overall and high-grade serous ovarian cancer (HGSOCs) were estimated
236 sis of tumor microenvironment composition in high-grade serous ovarian cancer and follicular lymphoma
237 breast cancer patient-derived xenografts and high-grade serous ovarian cancer cell lines and discover
238 2 is functionally silenced, HR+, CARM1-high, high-grade serous ovarian cancer cells become PARPi sens
239 peats (CRISPR)-mediated knockout of FABP4 in high-grade serous ovarian cancer cells reduced metastati
241 n the fallopian tubes (the site of origin of high-grade serous ovarian cancer), and whether such chan
243 rategy to selectively target BRCA1-deficient high-grade serous ovarian cancer, which is characterized
251 rotein glycosylation in the heterogeneity of high-grade serous ovarian carcinoma (HGSC), we perform m
254 es have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but their i
257 n is expressed in many carcinomas, including high-grade serous ovarian carcinoma, where it contribute
258 or lesion, respectively, for the majority of high-grade serous ovarian carcinomas (HGSOC) provide the
260 ogy and Obstetrics (FIGO; 1988) stage IC-IIA high-grade serous, clear cell, or any poorly differentia
261 en aged 18 years and older with stage III/IV high-grade serous, endometrioid, or clear cell ovarian c
263 ctal carcinomas in situ (88% intermediate or high grade [seven of eight]) and 18 invasive cancers (14
264 L (LSIL) at baseline, risk of progression to high-grade SIL (HSIL) and the clearance rate were estima
266 ILs) at baseline, the risk of progression to high-grade SILs (HSILs) and the clearance rate were esti
268 first lentiviral vector induced pig model of high-grade spinal cord glioma and may potentially be use
269 present study, we report the production of a high-grade spinal cord glioma model in pigs using lentiv
270 cord glioma (SCG) patients, particularly in high-grade spinal gliomas (Grade IV) known as glioblasto
272 analysis were conducted with histologic anal high-grade squamous intraepithelial lesion (A-HSIL) as t
273 y and specificity for a combined endpoint of high-grade squamous intraepithelial lesion (HSIL) and an
274 aharan Africa, are at high risk for cervical high-grade squamous intraepithelial lesions (HSIL) and c
275 pathology-predict anal HPV16 infection, anal high-grade squamous intraepithelial lesions (HSIL) and,
276 rological and serological predictors of anal high-grade squamous intraepithelial lesions (HSIL) in hu
277 s Terminology (LAST) in low-grade (LSIL) and high-grade squamous intraepithelial lesions (HSIL), and
280 f residual and/or recurrent high-grade CIN2+/high-grade squamous intraepithelial lesions post-treatme
283 entify MRI features that are associated with high-grade STS (grade III) and to determine the relation
285 ts with carcinoma in situ (with or without a high-grade Ta or T1 tumour) had a complete response with
287 In the tumor region, CMRO(2) was reduced (high-grade tumor CMRO(2), 0.23 mumol/g/min +/- 0.07; low
289 molecular advances, the clinical outcomes of high grade tumors, including H3K27M diffuse midline glio
291 metastasis, and specifically associated with high-grade tumors and poor prognoses in breast cancers.
294 gallium 68 DOTATATE PET/CT, and in cases of high-grade tumors, they were also evaluated with fluorin
295 -metastatic R0 or R1 low-grade, or <=5 cm R1 high-grade tumour); intermediate (non-metastatic R0 or R
297 papillomavirus-16 incidence was higher among high-grade versus no lesion at baseline (adjusted incide
300 f diffuse infiltrating gliomas, particularly high grade, which leads to a potential treatment delay f