ライフサイエンスコーパス: high-priority

1 lopment of a safe and effective vaccine is a high priority.

2 effective vaccine against Ebola virus is of high priority.

3 opment of next-generation vaccines are now a high priority.

4 pogenic forcing on the marine biosphere is a high priority.

5 s with fewer subsequent symptoms should be a high priority.

6 prevent congenital HCMV infection remains a high priority.

7 genes shape the development of IBD is also a high priority.

8 lines to include this population should be a high priority.

9 , making the development of new treatments a high priority.

10 uals, and the development of a vaccine is of high priority.

11 ving therapeutic approaches to HSE remains a high priority.

12 human T-cell memory needs to be explored at high priority.

13 is of their cellular entry pathway remains a high priority.

14 ted clearance of virus-producing cells is of high priority.

15 ing SCD prevention and treatment should be a high priority.

16 and the efficacy of protease inhibitors is a high priority.

17 betes, so disease prevention should be given high priority.

18 unctional antibodies against HIV-1 remains a high priority.

19 ilable, making the discovery of antivirals a high priority.

20 The search for novel medications is of high priority.

21 n to limit the impact of influenza remains a high priority.

22 fective vaccine design against this virus of high priority.

23 of immunophenotyping procedures has become a high priority.

24 these enzymes for drug design is currently a high priority.

25 chievement of high spatial resolution are of high priority.

26 where profit is minimal and therefore given high priority.

27 sk among African-American adults should be a high priority.

28 condary prevention of recurrent stroke are a high priority.

29 pondents said that achieving follow-up was a high priority.

30 ecreasing total antimicrobial use is also of high priority.

31 ted, thus development of new therapeutics is high priority.

32 rtemisinin-based combination therapies, is a high priority.

33 ntifies asthma as a public health problem of high priority.

34 oniazid for drug-resistant tuberculosis is a high priority.

35 on the activity of different IFN pathways a high priority.

36 earch for novel therapeutic candidates is of high priority.

37 etter-tolerated agents for treating HCV is a high priority.

38 cate that targeting of a gene should receive high priority.

39 ed from prospectively phenotyped cases was a high priority.

40 cells makes understanding their regulation a high priority.

41 rformance in real world settings should be a high priority.

42 e determinants of response to treatment is a high priority.

43 , prevention of this global scourge deserves high priority.

44 tions and chemistry, searching for them is a high priority.

45 l fuels make switching to low-carbon fuels a high priority.

46 tly characterize measles susceptibility is a high priority.

47 anners should make access to this practice a high priority.

48 sks, as the safety of allergic consumers has high priority.

49 e development of an anticocaine medication a high priority.

50 of their developmental programs was deemed a high priority.

51 p; biological sciences have never been given high priority.

52 vaginal ring delivery systems now becoming a high priority.

53 uction into clinical diagnostics should be a high priority.

54 e effective and better tolerated agents is a high priority.

55 w approaches to control body weight remain a high priority.

56 of operating room contamination should be a high priority.

57 ysical function decline, and disability is a high priority.

58 stribution and translation is regulated is a high priority.

59 ector and vector-pathogen interactions are a high priority.

60 e in vivo characteristics of SARS-CoV-2 is a high priority.

61 ainst congenital cytomegalovirus (cCMV) is a high priority.

62 of food intake and dietary intake data is a high priority.

63 ducts on coastal ecosystems are considered a high priority.

64 nt accessibility makes vaccine development a high priority.

65 ergence of resistance on this continent is a high priority.

66 ng clinically beneficial NK phenotypes is of high priority.

67 development of novel treatments for CDI is a high priority.

68 ne options for tobacco-associated NSCLC is a high priority.

69 cosystems and during their restoration was a high priority.

70 ment of a cytomegalovirus (CMV) vaccine is a high priority.

71 ng strategies to break immune tolerance is a high priority.

72 developed: 1) Mealtimes should be viewed as high priority.

73 s' responses, 9 questions were classified as high-priority.

74 rovirus, rotavirus, and Campylobacter remain high priorities.

75 eloping noninvasive treatment modalities are high priorities.

76 emory and coping with HIV-1 diversity remain high priorities.

77 uestions, 22 questions met our definition of high priority: 9 of 22 concerned the effectiveness of an

78 s in this Lancet Series, which each identify high-priority actions on key obesity issues and challeng

79 s model predicted 4,001 chemicals (12.3%) as high priority actives and 6,742 potential actives (20.8%

80 The high-priority ADHD candidate genes were significantly co

81 ported CNVs, of which they classified 432 as high-priority ADHD candidate genes.

82 nnected protein modules were found among the high-priority ADHD genes.

83 is an arenavirus identified as a category A high-priority agent.

84 ment of an IKK-specific inhibitor has been a high priority, although it remains unclear whether syste

85 of the RSV RNA synthesis machinery remains a high priority among the NNS RNA viruses.

86 alth declared the prevention of meningitis a high priority and asked the World Health Organization (W

87 f urgent priority for further action, 37% as high priority, and 4.2% as medium priority.

88 ion and treatment of comorbidities must have high priority, and a separate section in the document ad

89 trate that this line of work should be given high priority, and they set the stage for additional res

90 solation of specific species of RNA became a high priority, and we sequenced a small segment of the 3

91 ctive antigens where we identify three novel high priority antigens for future evaluation.

92 These analyses identified two high priority areas for future research and conservation

93 The goal was to define high priority areas of investigation that will soon be m

94 rition Research Needs focus on the following high priority areas: 1) variability in individual respon

95 e and patient volume can be used to identify high-priority areas for quality improvement from a popul

96 High-priority areas for research included: better defini

97 The ARLG has identified 4 high-priority areas of research: infections caused by gr

98 These high-priority areas, combined with areas of high priorit

99 l research that addresses 1 or more of these high-priority areas.

100 penem-resistant Enterobacteriaceae (CRE) are high-priority bacterial pathogens targeted for efforts t

101 nserving these last intact areas should be a high priority before they are completely lost.

102 ium falciparum and is therefore considered a high priority blood-stage malaria vaccine candidate.

103 ign for this fast acting and extremely toxic high priority BoNT E.

104 at the top-ranked antigens can be considered high-priority candidates for diagnostic development.

105 A subset of high-priority candidates was validated, including Myo16,

106 identified 106 candidate genes, including 14 high-priority candidates.

107 A total of nine genes were identified as high-priority candidates.

108 s heparin (Hep) and heparan sulfate (HS) are high-priority carbohydrates for Bacteroides thetaiotaomi

109 Board of Trustees believes that myopia is a high-priority cause of visual impairment, warranting a t

110 te change and extremes projections remains a high-priority challenge, especially since recent observe

111 nd/or flavoring chemical on either the FEMA "High Priority Chemicals" or FDA Harmful and Potentially

112 High-priority chemicals become targets for further data

113 chrane reviews published up to March 2016 to high-priority clinical research questions.

114 identifies specific antigen combinations for high-priority clinical testing and establishes a general

115 e application of fluidic platforms in recent high-priority colloidal nanomaterial studies and their p

116 dicitis and gastrostomy should be considered high-priority conditions among pediatric surgeons.

117 gnostics and vaccine candidates against this high priority coronavirus.

118 gh co-incident poverty and solid-fuel use as high-priority counties for research into potential healt

119 , newborn, and child health interventions in high priority countries.

120 The 18 high-priority countries in eastern Europe and central As

121 losis among new tuberculosis cases in the 18 high-priority countries in the WHO European Region.

122 There is a high-priority demand for general methods allowing access

123 we proposed element optimization priorities: High priority (deoxidized water and fuel), medium priori

124 munity that led to the identification of the high-priority diagnostic needs in tuberculosis.

125 The high-priority diagnostic needs included (1) a sputum-bas

126 Subsequently target product profiles for the high-priority diagnostic needs were developed and review

127 irus is an important pathogen in a number of high-priority domains: it is the most common cause of di

128 one and cytoskeletal modulator, HSPB1, among high-priority downregulated candidates in Tdrd7-/- lens.

129 ed egress.IMPORTANCE Ebola virus (EBOV) is a high-priority, emerging human pathogen that can cause se

130 Few studies addressed other high-priority evidence gaps.

131 can serve to focus experimental resources on high-priority experimental tasks.

132 he flavoring chemical diacetyl and two other high-priority flavoring chemicals, 2,3-pentanedione and

133 Gap analysis shows high priorities for antelope conservation to include cre

134 s identified by the Institute of Medicine as high priorities for cardiovascular CER.

135 new species were identified as particularly high priorities for eradication should they establish in

136 outcomes in quality-measurement systems are high priorities for improving the processes and outcomes

137 icals, and climate-related factors should be high priorities for incorporation into upcoming iteratio

138 otics and bacterial vaccines, should also be high priorities for pandemic planning.

139 Which populations of children are high priorities for study?

140 omologue genes and 2 zebrafish homologues of high priority for ACTC1.

141 This should be a high priority for anesthesiology departments to ensure d

142 of TB among HIV-infected mothers should be a high priority for communities with significant HIV/TB bu

143 ly species, which are rare, threatened and a high priority for conservation worldwide.

144 nding how SARS-CoV-2 enters human cells is a high priority for deciphering its mystery and curbing it

145 the burden of unsafe abortion, and remains a high priority for developing countries.

146 In addition, the results suggest a high priority for earlier proactive diagnosis and interv

147 Over 70% of taxa are identified as high priority for further collecting in order to improve

148 s, others indicated relevant candidates with high priority for further experimental validation.

149 ts relevant to aggressive skin SCC deserve a high priority for future clinical drug development.

150 e effects on ecosystem functions should be a high priority for future research.

151 Preventing HIV-1 transmission is a high priority for global health.

152 disease; thus, coinfected individuals are at high priority for HCV treatment.

153 ance to broadly neutralizing antibodies is a high priority for human immunodeficiency virus (HIV) res

154 ing the development of effective therapies a high priority for improving human health.

155 es between Europe and the United States is a high priority for improving long-term graft survival.

156 Young children remain a high priority for influenza vaccination while the world

157 al influenza vaccine should continue to be a high priority for lung transplant patients.

158 ccines and immune biomarkers of malaria is a high priority for malaria control and elimination.

159 to global immunisation programmes has been a high priority for many international agencies, including

160 acotherapies that promote remyelination is a high priority for multiple sclerosis (MS), due to their

161 atment strategies for heart failure remain a high priority for ongoing research due to the profound u

162 high-priority areas, combined with areas of high priority for other taxonomic groups and with social

163 her than future improvement, appears to be a high priority for patients.

164 n resource-poor settings, and this must be a high priority for policy makers and health care professi

165 of newly founded, isolated populations is a high priority for preventing damages.

166 of a prophylactic vaccine against HCMV is of high priority for public health.

167 Bridging the spatial gap should be a high priority for research and will require gathering cl

168 d nations, Campylobacter infections remain a high priority for research efforts to improve prevention

169 ce to ART and the partner drugs has become a high priority for resistance containment and malaria man

170 screening (born 1945-1965) for HCV may be a high priority for safety net hospitals.

171 the ecological impacts of acidification is a high priority for science, management, and policy.

172 that repair and replace diseased arteries a high priority for the cardiovascular research community.

173 terising the reservoir for HIV-1 on ART is a high priority for the design of curative interventions.

174 Although of high priority for the development of genetic tools to co

175 ting variability and uncertainty should be a high priority for the future of the Cardiac Physiome.

176 t rehospitalizations and adverse events is a high priority for the growing population of patients who

177 parative effectiveness research questions as high priority for the management of DR, including DME, b

178 rs highlight clinical approaches that are of high priority for the useful medical application of meta

179 of optimal prime-boost vaccine regimens is a high priority for the vaccine development field.

180 y neutralizing antibodies [bNAbs]) remains a high priority for the vaccine field.

181 Neutralizing antibodies (nAbs) are a high priority for vaccines that aim to prevent the acqui

182 114 as containing likely errors, and thus of high-priority for resequencing.

183 y for dissolution and transformation fills a high priority gap in nanomaterial hazard assessment and

184 To identify high-priority general pediatric surgical procedures for

185 These strategies have identified several high priority genes and developmental pathways that like

186 iagnosis by allowing researchers to sequence high priority genes at much higher depths and at a fract

187 olecular subnetworks and validating specific high-priority genes, we identify novel components of the

188 ould prove useful in the annotation of other high priority genomes, especially human and other mammal

189 Multistep regulation of GS shows the high priority given by organisms to regulating and ensur

190 zation of changes in beta-cell mass remain a high-priority goal.

191 Moving forward there are at least three high priority goals for anti-HIV drug delivery (DD) rese

192 uide discussion by defining a common core of high-priority goals while highlighting emerging opportun

193 i and possess antibacterial activity against high-priority Gram-negative pathogens.

194 eted cultivation of a microorganism from the high-priority group of the Human Microbiome Project's "M

195 Vaccine delivery to this high-priority group should be improved.

196 ns for the routine vaccination of persons in high-priority groups, US vaccination rates remain too lo

197 Therefore, high priority has been given to research investigating t

198 overage should be considered alongside other high-priority health interventions competing for health

199 ling-up ART should be considered among other high-priority health interventions competing for health

200 and cryptosporidiosis, in particular, are of high priority; however, there are few chemically validat

201 The high-priority (HP) pool, containing genes encoding a Lom

202 oduct antibiotics that are effective against high-priority human pathogens such as methicillin-resist

203 We considered questions as high priority if at least 75% of respondents to both rou

204 Despite its high priority, implementation of maternal health care ha

205 s, such as remission induction failure, is a high priority in APL, especially because such events rep

206 imaging cell fate after transplantation is a high priority in both basic research and clinical transl

207 in the peripherin 2 (PRPH2) gene should be a high priority in families with highly variable retinal d

208 ifying non-addictive opioid medications is a high priority in medical sciences, but mu-opioid recepto

209 lescent health and wellbeing should be given high priority in national and international policy.

210 oward the class III obese cohort should be a high priority in nutrition medicine.

211 to screen for prion infection in blood is of high priority in order to facilitate the prevention of t

212 e critically ill patient that are considered high priority in severe sepsis, and pediatric considerat

213 of the critically ill patient and considered high priority in severe sepsis; and 3) pediatric conside

214 ly serious vaccine reactions was therefore a high priority in the design and implementation of those

215 rug targets and chemotherapeutic agents is a high priority in the fight against cancer.

216 ics to prevent pathogenic infection is given high priority in the twenty-first century.

217 A high priority in vaccine research is the development of

218 al arousal enhances perception and memory of high-priority information but impairs processing of othe

219 lations across neural ensembles transmitting high-priority information.

220 n that in cognitive behavioral therapy (CBT) high priority is given to the "semantic structure." We a

221 SCAD and pregnancy after SCAD, and highlight high-priority knowledge gaps that must be addressed.

222 Finally, we suggest a high-priority list of 29 EGs with potential ASD risk as

223 ame subjects, we computationally generated a high-priority list of miRNA-mRNA pairs in which the DE p

224 ith unexpected epigenomic signals, to define high-priority marks for new experiments and to delineate

225 28 high priority miRNA candidates showing abnormal expressi

226 ble-isotope labeling technique to illuminate high-priority mLANA-interacting host proteins.

227 alleles in these 36 sequenced classical and high-priority mouse inbred strains.

228 transmission of CWD is as yet unclear but a high priority must be to minimize further spread of the

229 , an industrial solvent, in breast milk as a high priority need for risk assessment.

230 This method meets a documented high priority need in regulatory science as applied to N

231 h report highlights a focused set of 4 to 15 high-priority needs with an accompanying description of

232 Glycosaminoglycans represent an important, high priority, nutrient source for the HGM.

233 b governments have not placed a sufficiently high priority on addressing the high prevalence of non-c

234 nce shows that people who place a relatively high priority on materialistic values/goals consume more

235 erapy continues, safety considerations are a high priority, particularly those that remove nonhuman a

236 (MDR) Salmonella enterica has been deemed a high-priority pathogen by the World Health Organization.

237 ilus influenzae, M. catarrhalis has become a high-priority pathogen in otitis media.

238 ease.IMPORTANCE Ebola virus (EBOV) remains a high-priority pathogen since it continues to cause outbr

239 Staphylococcus aureus is also a "high priority" pathogen which is a major cause of seriou

240 ffective therapeutics against biodefense and high-priority pathogens, including filoviruses (Ebola an

241 tures has made IBD both an appropriate and a high-priority platform for translatable research in host

242 s may be an initial target population, other high-priority populations regardless of symptoms-includi

243 ing to implement and often less sensitive in high-priority populations.

244 nervous system infections in humans and are high-priority potential bioterrorism agents.

245 ss research agenda is proposed: Two of the 9 high-priority questions require new primary research (su

246 cent meeting of expert panels, essential and high-priority recommendations to propel brain barrier re

247 interact with norepinephrine (NE) to enhance high priority representations and out-compete or suppres

248 context of widespread suppression, enhancing high priority representations while suppressing the rest

249 (>75% agreement among panelists) identifying high-priority research areas during pregnancy, including

250 t of neurobiological correlates of AN remain high-priority research areas.

251 xygen reduction reaction (ORR) is one of the high-priority research directions for commercialization

252 Identification of high-priority research needs could potentially speed the

253 ncludes with a series of recommendations for high-priority research subtopics at the "bio-nanosheet"

254 lopment of sensitive homogeneous assays is a high-priority research target for clinical diagnostics.

255 urveillance efforts from targeted testing of high-priority samples to comprehensive testing of large

256 tory actions and enhancing the processing of high-priority sensory signals for immediate or future ex

257 their share deficits were reduced by 95% in high-priority share classes.

258 n sanctuary sites such as the lymph nodes, a high priority should be placed on improving ART regimes

259 speed the development and implementation of high-priority, stakeholder-engaged research.

260 expected, thus leading to significantly more high-priority status listings than anticipated.

261 by ensuring that the tetrameric complex is a high-priority substrate.

262 ower priority glycans because re-introducing high priority substrates late in culture re-initiates re

263 High-priority subtopics identified included heart failur

264 ied major gaps that should be addressed with high priority, such as understanding how immunological a

265 rian cancer predisposition that has become a high priority target for improving the classification of

266 ute upper respiratory infections (URIs) is a high-priority target for antimicrobial stewardship that

267 not meet the performance requirements of the high-priority target product profiles (TPP) published by

268 rculosis that meet the specifications of the high-priority target product profiles (TPPs) is currentl

269 Existing high-priority target product profiles (TPPs) of the Worl

270 terminant during infection(2-5), making it a high-priority target.

271 ult blood were detected in UCB and represent high-priority targets for immediate validation.

272 ation, and appendectomy should be considered high-priority targets for prevention efforts within pedi

273 The detection of life markers is a high priority task in the exploration of the Solar Syste

274 of differentially expressed genes has been a high priority task of downstream analyses to further adv

275 nts of protection against HIV infection is a high priority that will require careful selection of hig

276 monary disease (COPD) has not been seen as a high priority, the past decade has seen a substantial in

277 nature of our patients, frailty has become a high-priority theme in cardiovascular medicine.

278 in in chemotherapeutic resistance makes it a high priority therapeutic target.

279 redicts cardiovascular risk and represents a high-priority therapeutic target to ameliorate the globa

280 ) point to potential relevance of CD151 as a high-priority therapeutic target, with relative selectiv

281 pathogenesis and drug resistance makes it a high-priority therapeutic target.

282 e, and Salmonella typhi were included in the high-priority tier.

283 re was insufficient new evidence to assign a high priority to a comprehensive systematic review for e

284 al contribution to total heterozygosity gave high priority to Criollo pig breeds, whereas Weitzman pr

285 assessing chemical exposures in infants is a high priority to federal agencies and local communities.

286 rivers, protecting plant diversity may be of high priority to maintain the biodiversity and functioni

287 Against this background, WHO made it a high priority to provide the present fetal growth charts

288 and developing a prophylactic vaccine is of high priority to public health.

289 more detailed guidance for each of the 4 WHO high-priority TPPs.

290 High-priority triage with enhanced operating room flexib

291 Functional analysis of high-priority variants shows the potential function of S

292 ng with respect to the central processing of high-priority versus low-priority stimuli, but it requir

293 arch studies by providing investigators with high-priority, well established, low-burden measurement

294 The goal of PhenX is to identify 15 high-priority, well-established, and broadly applicable

295 Genes with high priority were further subjected to validation using

296 The highest ranked Gram-positive bacteria (high priority) were vancomycin-resistant Enterococcus fa

297 utralizing antibodies and this property is a high priority when developing an HIV vaccine.

298 ovel diagnostic products that may meet the 4 high-priority WHO TPPs and thus enable adequate evidence

299 the wild relatives (categorized as urgent or high priority), with 83 taxa absent from conservation re

300 halt an influenza epidemic or pandemic are a high priority, with an emphasis on vaccines and antivira