ライフサイエンスコーパス: high-turnover

1 en anthracene and maleimide derivatives with high turnover.

2 aflatoxin B1, naphthalene, and styrene, with high turnover.

3 ecay showed the Aire(+) population to have a high turnover.

4 h and will be greatest in populations with a high turnover.

5 roendocrine origin, but also in tissues with high turnover.

6 ty performed differently in times of low and high turnover.

7 ithin a single polypeptide with an extremely high turnover.

8 F-actin and regulatory proteins that undergo high turnover.

9 High turnovers (10(5)) and turnover frequencies (10(4) h

10 es P450 2D6, 3A4, and 4F2 are high-affinity, high-turnover anandamide oxygenases in vitro, forming th

11 zylic, allylic or alpha-amino C-H bonds with high turnover and excellent selectivity.

12 were mainly characterized by low dispersal, high turnover and genetically differentiated populations

13 otein kinase can simultaneously achieve both high turnover and good substrate binding properties.

14 always, associated with tissues that display high turnover and high levels of protein synthesis.

15 ique infection control challenges because of high turnover and medically complex residents.

16 ch as formate dehydrogenase-can operate with high turnover and selectivity at a minimal overpotential

17 These include constraints of time, high turnover and the need for early and effective disch

18 Epithelial and hematopoietic cells have a high turnover and their progenitor cells divide continuo

19 ve formation of beta- and gamma-lactams with high turnovers and promising enantioselectivities.

20 workforce marked by poor working conditions, high turnover, and critical worker shortages.

21 rated woven structure, increased osteocytes, high turnover, and reduced maturation.

22 os identified a pool of dynamic F-actin with high turnover at EC junctions in vessels.

23 s, as observed previously, with particularly high turnover at super-enhancers.

24 Here we show high turnover between symbiont-bearing warm-water and hi

25 known actions of TNFalpha, we attribute the high-turnover bone loss to an expanded osteoclast precur

26 Therapies tailored specifically to low- or high-turnover bone may treat renal osteodystrophy more e

27 ls expressed telomerase and, in spite of the high turnover, built up a telomeric reserve.

28 sign of a supramolecular catalyst capable of high-turnover catalysis is reported.

29 drogen bonding with C-H activation to obtain high-turnover catalytic regioselective functionalization

30 f the proliferation of lymphocytes and other high-turnover cell populations in vivo can be accomplish

31 We found that, without prior assumptions, high turnover could be used to identify regions involved

32 This high turnover creates intraspecific gene content variati

33 phoribosyl pyrophosphate amidotransferase, a high-turnover enzyme of the purine biosynthetic pathway

34 se superfamily has evolved in the "extremely high turnover" fashion: numerous losses and duplications

35 enase enzymes use Ni and Fe to oxidize H2 at high turnover frequencies (TOF) (up to 10,000 s(-1)) and

36 : those that oxidize organic substrates with high turnover frequencies (TOFs) up to 560 s(-1) and tho

37 or quinolone synthesis, achieving remarkably high turnover frequencies (TOFs).

38 e showed that Au/Pd-TiO2 catalysts give very high turnover frequencies (up to 270,000 turnovers per h

39 fficiency (FE(CO)), and Co(2)BiCage achieves high turnover frequencies (~1300 h(-1), eta = 520 mV) wi

40 l or aryl) at the 5 position are crucial for high turnover frequencies and good enantioselectivities.

41 Together, it achieves high turnover frequencies of 4.2 s(UPD)(-1) (3.0 s(BET)(

42 The high turnover frequencies of CoFeOx and CoFeNiOx at low

43 s sets in at about 300 mV overpotential with high turnover frequencies that outperform other metal-or

44 Redox enzymes have high turnover frequencies, typically 10-1000 s(-1), and

45 ultralow Tafel slope (25 mV dec(-1) ), and a high turnover frequency (3.57 H(2) s(-1) ) in alkaline m

46 The catalyst yields a high turnover frequency (35.1 +/- 5.2 s(-1)) and mass ac

47 activation energy (10.8 kcal mol(-1)) and a high turnover frequency (483 and 1336 hr(-1) at 1-bar an

48 ity than iridium nanoparticles with a record-high turnover frequency (TOF) of 24.3 e(-) site(-1) s(-1

49 -1).h(-1) with nearly 100% selectivity and a high turnover frequency (TOF) of 31,019.2 h(-1) at 150 d

50 Under a strong acidic environment, a high turnover frequency (TOF) of ~2.2 x 10(-3) s(-1) per

51 Our study reveals the origin of the high turnover frequency (TOF), and excellent durability

52 alyst oxidizes water with low overpotential, high turnover frequency and minimal degradation.

53 pable of forming molecular dihydrogen with a high turnover frequency at low overpotential.

54 ving cells-generating NAD(*) radicals with a high turnover frequency in biological media.

55 fer at pH 9.35, with low overpotential and a high turnover frequency of 129 s(-1) (peak current measu

56 ty for CO(2) reduction to formic acid with a high turnover frequency of 21.1 s(-1).

57 e and 33 % vacancies exhibited unprecedented high turnover frequency of 29.5 h(-1) in visible-light-d

58 ater oxidation under these conditions with a high turnover frequency of 33 s(-1).

59 The Er catalyst achieves a high turnover frequency of ~130,000 h(-)(1) at 500 mA cm

60 MMBL polymerization reaches an exceptionally high turnover frequency up to 122 s(-1) and a high initi

61 catalyst (Ir3) with strong light absorption, high turnover frequency, and excellent biocompatibility

62 igh intrinsic activity as reflected from its high turnover frequency, which is more than two orders o

63 yst transfer and its effect on the continued high turnover frequency.

64 alyst is endowed with a good stability and a high turnover frequency.

65 It was assumed that they have a high turnover from blood-borne monocytes.

66 pared with normal or low turnover, bone with high turnover had material and nanomechanical abnormalit

67 romising tool in transfusion medicine and in high turnover/high activation platelet disorders.

68 1.09 [95% CI, 1.07-1.11]), 39% lower odds of high turnover hospitalization (odds ratio [OR], 0.61 [95

69 me measures included (1) length of stay, (2) high turnover hospitalization, (3) total hospital cost,

70 Despite the high turnover in active ensemble membership across learn

71 e upslope shift may have been accelerated by high turnover in canopy trees that provided opportunitie

72 lower bioavailability in rat and dog, and a high turnover in human hepatocytes.

73 Problems with high turnover in nursing and of maintaining adequate num

74 ter molecule, and short residence times with high turnover involving multiple water molecules.

75 oxidation actuate amide bond formation with high turnover is offered.

76 In addition, a high turnover number (>3000) can be achieved.

77 f carboxylic acids has been developed with a high turnover number (>99 000) and turnover frequency (>

78 rdered loops that may explain the relatively high turnover number (280 s(-1) at pH 7.0) toward CDNB.

79 polymerization of acetylenes and exhibits a high turnover number (4371), activity (1.05 x 10(6) g(PP

80 (-1) g(-1) under full arc), which leads to a high turnover number (TON) of over 641 after 6 h.

81 ght-induced air-water-CO(2) reduction with a high turnover number (TON) of ~10(6)-10(8) (mols of prod

82 rate reductase (Frd) is notable both for its high turnover number and for its production of substanti

83 Using this mechanistic knowledge, a record high turnover number of >30 000 was achieved for the hyd

84 activity of 1.78 mol.g(cat)(-1).h(-1) with a high turnover number of 94,769 mole ethylene per mole Cr

85 a high level of expression and a relatively high turnover number of the efflux pumps in gram-negativ

86 The DNA-scaffolded catalyst maintained a high turnover number upon dilution and exhibited 190-fol

87 ithout loss of activity and selectivity, and high turnover number was obtained.

88 tudies of P450BM-3 due to its high affinity, high turnover number, and increased solubility as compar

89 The latent catalytic behavior, the high turnover number, and the high anti-Markovnikov sele

90 e reaction has also been demonstrated with a high turnover number.

91 High turnover numbers (ca. 54,000) and turnover frequenc

92 the palladacycles have been used to generate high turnover numbers (TON's) and turnover frequencies (

93 s (25 degrees C, 1 bar N(2)O), together with high turnover numbers (TON, up to 6700) and turnover fre

94 is long-lived and remarkably efficient with high turnover numbers (TONs) and turnover frequencies (T

95 e and aziridine carboxylate derivatives with high turnover numbers (TONs).

96 High turnover numbers (up to 2000 for homocoupling of 1-

97 tivity to catalytic reactions and to achieve high turnover numbers and high yields.

98 ons to alkynes and cycloisomerizations, with high turnover numbers at room temperature or slightly el

99 Even under non-optimised conditions, high turnover numbers for coupled FOx/peroxygenase catal

100 ctional groups and displayed unprecedentedly high turnover numbers of approximately 2.5 x 10(6) and t

101 Impressively, sal-Fe-MOF displayed very high turnover numbers of up to 145000 and was recycled a

102 ly, the Mg-functionalized MOF displayed very high turnover numbers of up to 8.4 x 10(4) for ketone hy

103 High turnover numbers reflect the enhanced stability of

104 The latent reaction kinetics and high turnover numbers seen for 1-COD after thermal trigg

105 ge of ethers with excellent mass balance and high turnover numbers under 1 atm of O2 with no need for

106 eta-chloroperbenzoic acid (mCPBA) occur with high turnover numbers under mild conditions, but the mec

107 oxygen production rates up to 286 s(-1) and high turnover numbers up to 55,400.

108 The stability of the Cu(II) state leads to high turnover numbers, >1000 for the coupling of phenoxi

109 road detection window ranging from single to high turnover numbers.

110 reaction conditions, thus accounting for the high turnover numbers.

111 lyze oxidation reactions, in some cases with high turnover numbers.

112 te carbon monoxide from CO2 selectively with high turnover numbers.

113 were defluorinated with high conversions and high turnover numbers.

114 y fast gliding motility, the parasite uses a high turnover of actin polymerization and adhesion sites

115 We found a high turnover of AMF with < 12% of VT present in all veg

116 e from degradation of nucleic acids due to a high turnover of cells in the bladder itself.

117 -mediated drug disposition consistent with a high turnover of endogenous uPA.

118 The testis exhibits relatively high turnover of endothelial cells.

119 iency accelerates telomere shortening during high turnover of hematopoietic cells and promotes telome

120 enetic determination of flowering time and a high turnover of individual plants argues strongly for t

121 equate implementation of the intervention, a high turnover of patients in the intervention units, com

122 cription from the rRNA promoters with a very high turnover of RNA polymerase.

123 re released into the intestinal lumen by the high turnover of the intestinal epithelium.

124 on a relatively long time scale despite the high turnover of the microtubules that comprise it.

125 Our data show a high turnover of transcriptional states between taxa and

126 This was accompanied by a high turnover of tumor cells.

127 to the next or within epidemics) there is a high turnover of variants within genotypes.

128 onstrate that most chromatin proteins have a high turnover on chromatin with a residence time on the

129 in patients with end-stage renal disease: a high-turnover osteodystrophy characterized by osteitis f

130 e-dependent loss of bone mass that resembles high-turnover osteoporosis in humans.

131 ay present a viable therapeutic strategy for high-turnover osteoporosis.

132 vere bone loss, as reported in patients with high-turnover, postmenopausal osteoporosis.

133 abnormalities in the posttransplant period (high turnover posttransplant) were the most reliable pre

134 ells are a distinctive TRM population with a high turnover rate and a unique phenotype influenced by

135 n stability and found that the protein has a high turnover rate and is degraded by the proteasome 26S

136 membrane channels in embryonic cones have a high turnover rate because inhibition of protein synthes

137 This high turnover rate ensures that the mesenteric LN mainta

138 This high turnover rate necessitates profound control mechani

139 f nuclear bomb test-derived (14)C revealed a high turnover rate of endothelial cells throughout life

140 This high turnover rate reveals a large and rapid mycorrhizal

141 ly bound pool, and a dynamic bound pool with high turnover rate that exchanges with the cytoplasmic p

142 a2+ exchanger (NCX1) is thought to achieve a high turnover rate, but all estimates to date are indire

143 sate for impaired mitochondrial function and high turnover rate.

144 (2+) and this protein possesses a relatively high turnover rate.

145 inally differentiated and short-lived with a high turnover rate.

146 ), (ii) a nonsense mutation (R150*) or (iii) high turnover rates (G134W).

147 ation of closed hexameric toroids capable of high turnover rates and amenable to allosteric regulatio

148 stability of pre-mRNA species with different high turnover rates and investigated potential correlati

149 Prototypical Group A hydrogenases have high turnover rates and remarkable energy efficiency.

150 treating FGE with copper(II) is required for high turnover rates and yields.

151 rs not previously considered as mediators of high turnover rates for C(2)-C(4) alkenes at cryogenic t

152 bstrate and 2,4,6-trichlorophenol also gives high turnover rates in enzymatic studies.

153 UD1, UD2, and UD3 exhibit high turnover rates of 55 +/- 4.7, 84 +/- 4.8, and 79 +/

154 sidence times around 1 to 2 s, and similarly high turnover rates of membrane-associated proteins in C

155 90% or higher ee, good regioselectivity, and high turnover rates).

156 Both Npas4 mRNA and protein had high turnover rates, and, at the protein level, degradat

157 ineages, male-biased genes do not experience high turnover rates, but instead reveal remarkable conse

158 the start of treatment and, for cancers with high turnover rates, combination therapy is less likely

159 maintain both high substrate affinities and high turnover rates, the phosphorylation of the yeast RN

160 erotonin (5-HT) and dopamine (DA) levels and high turnover rates, thus suggesting that central monoam

161 which are common in regulatory proteins with high turnover rates.

162 re in the mechanism of fumarate reduction at high turnover rates.

163 are dominated by weak ties characterized by high turnover rates.

164 n decoupling of the proton pump but maintain high turnover rates.

165 For very high-turnover rates, increasing the number of drugs used

166 in in the vicinity of the heme iron; (b) the high turnover regio- and stereoselective metabolism of a

167 Cytochrome P450 BM-3 catalyzes the high turnover regio- and stereoselective metabolism of a

168 Uremic mice exhibited high turnover renal osteodystrophy; treatment with sevel

169 o seed dispersal in forest and matrix, but a high turnover (replacement) in all these components.

170 nover was also significant (hazard ratio per high-turnover shift, 1.04; 95% CI, 1.02 to 1.06; P<0.001

171 In this large SARS-CoV-2 Delta outbreak in a high-turnover short-term rehabilitation unit, a low vacc

172 he pulse-chase model artificially eliminated high-turnover solutions.

173 rt a population of renal myofibroblasts in a high turnover state and in matrix deposition.

174 cantly reduced, and most TEM maintained very high turnover throughout anti-IL-15 treatment.

175 Here, we show that in a high-turnover tissue, severe damage to the differentiate

176 In cycling tissues that exhibit high turnover, tissue maintenance and repair are coordin

177 ncapping, causing defects most pronounced in high-turnover tissues including intestinal epithelium.

178 Maintenance of high-turnover tissues such as the epidermis requires a b

179 In high-turnover tissues such as the intestine, these adapt

180 rogressive atrophy and functional decline in high-turnover tissues.

181 ensure maintenance of tissue homeostasis in high-turnover tissues.

182 sin to switch during S phase from a state of high turnover to one capable of tenaciously holding sist

183 he poly(propylene oxide) in high yields with high turnover (TON>2000), which renders this the most ac

184 ent enantioselectivities and unprecedentedly high turnovers (TON up to 10 000) were achieved in the a

185 High turnover was seen at enhancers, as observed previou

186 , where normal mouse bone marrow cells (i.e. high turnover) were evaluated post labeling, demonstrate

187 , low in D-aspartate, may represent areas of high turnover where D-aspartate may be physiologically i