ライフサイエンスコーパス: hind paw

1 chanical hypersensitivity in the ipsilateral hind paw.

2 n the mechanical sensitivity of the affected hind paw.

3 d- and mechano-allodynia) in the ipsilateral hind paw.

4 in sensory and motor function in the treated hind paw.

5 later, they were infected with MAYV in their hind paw.

6 plete Freund's adjuvant (CFA) into the mouse hind paw.

7 light-evoked nociceptive stimulation to the hind paw.

8 n (50muL, 10%) in the plantar surface of the hind paw.

9 heat stimuli applied to their tumor-bearing hind paw.

10 ing task performed by the previously injured hind paw.

11 timuli applied to the plantar surface of the hind paw.

12 of 1% lambda-carrageenan into the mouse left hind paw.

13 Lewis rats by injecting carrageenan into the hind paw.

14 mechanical and hypotonic stimulation of the hind paw.

15 nts were acquired from sections of arthritic hind paws.

16 nization induced an erosive arthritis of the hind paws.

17 etermined in histology sections of arthritic hind paws.

18 ts following noxious heat stimulation of the hind paws.

19 nded to the proximal joints of the front and hind paws.

20 and (4) rats treated with formalin into the hind paw 30 min after subcutaneous morphine injection (m

21 sly, (2) rats treated with FORMALIN into the hind paw 30 min after subcutaneous normal saline injecti

22 ts develop hyperalgesia and allodynia in the hind paw after L5 spinal nerve ligation.

23 Having established facial and hind-paw allodynia as a useful animal surrogate of heada

24 Facial and hind-paw allodynia associated with dural stimulation is

25 IM elicited robust facial and hind-paw allodynia, which peaked within 3 hours.

26 nical or thermal stimulus to the ipsilateral hind paw and lower limb of the rat.

27 noxious thermal stimulus to the ipsilateral hind paw and lower limb.

28 pplied to different areas of the ipsilateral hind paw and lower limb.

29 cegepant produced a significant reduction in hind paw and orofacial mechanical withdrawal thresholds

30 he response to mechanical stimulation of the hind paws and face.

31 ia and mechanical allodynia occurred in both hind paws and forepaws by 7 d postlesion and were mainta

32 fied by measurement of ankle swelling in the hind paws and histologic examination.

33 liter) into the plantar surface of the right hind paw, and 24 rats were injected with 50 microliter s

34 vented the development of hypoalgesia in the hind paw, and reduced superoxide and nitrotyrosine level

35 Unlike the traditional hind paw assay, the time-course of nociceptive behavior

36 igation, but maintained in the contralateral hind paw at control levels.

37 anical thresholds [mean (standard deviation) hind paw baseline: 5.78 (2.81) g, Day 7: 3.34 (2.22) g,

38 onse to graded mechanical stimulation of the hind paws (brush, pressure, and pinch).

39 ntibody delayed the onset of swelling of the hind paws but, more importantly, inhibited the developme

40 n the tail were similar to those seen in the hind paw, but were limited to licking.

41 Noxious stimulation of the hind paw by subcutaneous injection of 0.5% formalin into

42 obes and received noxious stimulation to the hind paw by subcutaneous injection of 0.5% formalin solu

43 d as periarticular erythema and edema in the hind paws by days 24-26 after the first injection, with

44 n of TLQP-21-stimulated macrophages into rat hind paw caused mechanical hypersensitivity.

45 pain in which carrageenan injection into the hind paw causes hypersensitivity to heat stimuli, TNF-al

46 n, as well as reduced hypersensitivity after hind paw CCL5 administration upon Hdac6 knockdown in the

47 Histologic analyses were done on hind paws collected on day 32 following the pristane inj

48 the lymph nodes, liver, kidneys, spleen, and hind paw containing the injection site were removed and

49 ry function and on density of innervation in hind paws contralaterally as well as ipsilaterally to th

50 Histopathological examination of the left hind paw demonstrated that Fp.

51 s of different bending forces to the plantar hind paw, developed in the untrained group 3 weeks after

52 , tail, whisker, dorsal forepaws, and dorsal hind-paws do not significantly affect behavior of anteri

53 the effects of spinal adrenal transplants on hind paw edema and the anterograde transport of substanc

54 cell line) and using the carrageenan-induced hind paw edema model on rats.

55 Hind paw edema, inflammatory cell infiltration, and oste

56 ved sural and tibial nerve myelin thickness, hind paw epidermal innervation, and pAkt expression in d

57 d morphine resulted in significantly reduced hind paw flinching compared with morphine alone in the f

58 Robust formalin-evoked edema, as well as hind paw flinching, was observed in striated muscle cont

59 including the rota-rod, open-field tests and hind-paw footprint analysis.

60 Relative to hind paws, forepaws performed ~4 times more steps, they

61 rats under resting conditions and following hind paw formalin injection.

62 Using a rodent pain assay that combines the hind-paw formalin model with the place-conditioning para

63 tion potentials were weaker, and recovery of hind paw function was delayed but ultimately not impaire

64 domly assigned to five groups; each had both hind paws immersed in water at different temperatures (n

65 We induced unilateral inflammation of the hind paw in mice, and directly compared expression and f

66 increased withdrawal latency of the inflamed hind paws in the sham-operated rats but not in those wit

67 onse to mechanical or thermal stimulation of hind paws, in comparison to Taxol(R) administration at t

68 Hind paw incision was used in separate groups of animals

69 Rats that experience hind-paw incision injury at 3 days of age, display an in

70 y evaluated the efficacy of N-001 in a mouse hind-paw incision model by peri-incisional and popliteal

71 The injection of carrageenin into the rat hind paw induced a decrease in the mechanical nociceptiv

72 Injection of formalin into the hind paw induces a biphasic pain response; the first pha

73 taneous injection of formalin into the rat's hind paw induces microglial activation in the spinal cor

74 We established a S. aureus hind paw infection in diabetic db/db and nondiabetic Lep

75 Nondiabetic +/+ mice resolved the S. aureus hind paw infection within 10 days, whereas db/db mice wi

76 ale and female C57Bl/6 mice before and after hind paw inflammation by complete Freund's adjuvant (CFA

77 ted an antinociceptive effect in rats with a hind paw inflammation, without exhibiting characteristic

78 cal- and thermal-pain hypersensitivity after hind-paw inflammation compared with wild-type littermate

79 The hind paw inflammatory score showed a decrease in the int

80 stemically injected into rats prior or after hind paw injection of formalin.

81 Combined local insulin and PTEN siRNA hind paw injections improved abnormalities in chronic ex

82 model of experimental DPN, unilateral intra-hind paw injections of a PTEN siRNA and local insulin ha

83 Unilateral hind paw injections of complete Freund's adjuvant produc

84 hind-paw injury at Postnatal Day (PD) 2, (b) hind-paw injury at PD 5, (c) anesthesia exposure only on

85 igned to 1 of 4 experimental conditions: (a) hind-paw injury at Postnatal Day (PD) 2, (b) hind-paw in

86 Subjects receiving a unilateral neonatal hind-paw injury showed decreased mechanical threshold (h

87 only IL-1alpha was consistently detected in hind paw interstitial fluid in response to intradermal c

88 Immune challenge took place in the hind paw ipsilateral or contralateral to an injured scia

89 Sensitivity was lost in the hind paw ipsilateral to spinal nerve ligation, but maint

90 late test (52 degrees C): the mean (+/-S.D.) hind paw lick latency of rats in the high anti-NGF titer

91 ured before injection of formalin or CFA and hind paw licking/biting timed during the late-phase of t

92 Contralesional hind paws lost 54% of innervation in tibial-innervated e

93 e, reversible, dose-dependent attenuation of hind paw mechanical allodynia for up to 1h after adminis

94 In an arthritis model, hind paw mechanical hypersensitivity is exacerbated in m

95 orepaw steps were classified as exploratory, hind paw movement as locomotive.

96 1 area in both male and female mice disrupts hind paw movement during locomotion on a rotarod and a r

97 ) was implanted subcutaneously on the dorsal hind paw of C57 mice while the tumor-free contralateral

98 l), but local injection of PGE(2)-G into the hind paw of HbAA-BERK mice produced sensitization of noc

99 neously into the plantar portion of the left hind paw of male Holtzman-strain Sprague-Dawley rats.

100 us serotype 9 encoding CaV-abetalator in the hind paw of mice resulted in the expression of the prote

101 sponse when injected subcutaneously into the hind paw of mice.

102 thermal hyperalgesia when injected into the hind paw of mice.

103 te Freund's adjuvant subcutaneously into one hind paw of rats with dorsolateral funiculus lesions and

104 Arthritis was induced in the right hind paw of six rats; the left hind paw served as an int

105 on of Complete Freund's Adjuvant in the left hind paw of Sprague-Dawley rat.

106 was injected into the plantar surface of one hind paw of the rat to induce hyperalgesia in the inject

107 une response was observed bilaterally in the hind paws of animals subjected to unilateral mononeuropa

108 Swelling was also observed in the hind paws of hamsters infused with only Mphi-FBb or only

109 tion of CM from painful non-NF2 SWN into the hind paws of healthy mice evoked both more acute pain be

110 chemokine mRNA transcripts obtained from the hind paws of immunized mice, whereas FcgammaRI(-/-) mice

111 ng complete Freund's adjuvant (CFA) into the hind paws of rats.

112 V1-lineage afferents in the epidermis of the hind paws of the reporter mice showed that EGTA and MDL2

113 that challenging the skin of the calf of the hind paw or the cheek of previously sensitized mice with

114 ing S2 non-whisker S1 projections alters the hind paw orientation during locomotion, whereas manipula

115 ng S2->non-whisker S1 projections alters the hind paw orientation during locomotion, whereas manipula

116 Cre (+) Ppara (-/-) mice did not demonstrate hind-paw perfusion recovery after feeding fenofibrate.

117 uitry, we used an animal model of persistent hind paw peripheral inflammation.

118 ntly reduced pain-related behavior following hind paw plantar formalin injection in rats.

119 were significantly correlated with the RVS (hind paws R = -0.94, front paws R = -0.81, combined R =

120 icantly reduced capsaicin-induced changes in hind paw sensitivity to radiant heat and mechanical stim

121 Periorbital and hind paw sensory thresholds were measured to detect cuta

122 in the right hind paw of six rats; the left hind paw served as an internal control.

123 neurons across four diverse domains of mouse hind paw skin, including a recently described patch of p

124 responses were compared and were related to hind-paw skin temperatures measured during stimulation o

125 yographic responses to graded suprathreshold hind-paw stimuli in the 4 weeks following adult incision

126 cement on unmyelinated fiber function in the hind paw, sural nerve C-fiber morphometry, sciatic nerve

127 to IL-17 partially inhibited the significant hind paw swelling and histopathological changes observed

128 Inflammation (hind paw swelling) was quantified throughout the clinica

129 g gait, reluctance or inability to move, and hind paw swelling.

130 carrageenan (2%) into genital or nongenital (hind paw, tail, cheek) regions.

131 old (hyperalgesia) on the previously injured hind paw throughout development.

132 alysis, and immunohistochemistry; plasma and hind paw tissue levels of cytokines and chemokines (incl

133 Exposure of the hind paw to 1,500 J m(-2) UVB radiation caused an increa

134 aments applied to the plantar surface of the hind paw to assess mechanical hyperalgesia in HbSS and c

135 The sensitivity of the hind paws to noxious heat (Hargreaves test), innocuous t

136 When formalin was injected into mouse hind paws, to model inflammatory pain, SP16 dose-depende

137 itial development of neuropathic pain in the hind paw upon injury to the sciatic nerve, but the abnor

138 Severe swelling of the hind paws was detected 8 days after infection and increa

139 Swelling of the hind paws was detected in 100, 100, and 50% of hamsters

140 Swelling of the hind paws was detected within 8 h of infection, increase

141 Inflammation in the hind paws was evaluated by assessing cytokine and chemok

142 overy from anesthesia, motor function of the hind paws was scored as follows: 0, no evidence of defic

143 njection of carrageenan into the ipsilateral hind paw, was investigated.

144 y subcutaneous inoculation of QHGAD67 in the hind paws, was substantially increased compared to anima

145 ng complete Freund's adjuvant (CFA) into one hind paw, we systematically evaluated the anti-hyperalge

146 r 4 weeks of arthritis, mice were killed and hind paws were assessed histologically for joint damage.

147 Results demonstrated that inflamed hind paws were edematous, and the withdrawal thresholds

148 Hind paws were evaluated for histologic evidence of infl

149 nd the withdrawal thresholds of the inflamed hind paws were significantly lower after formalin or CFA

150 ar junctions of the lumbrical muscles of the hind-paw were vulnerable in both SMA and ALS, with a los

151 ulas, and sensory thresholds of the face and hind-paws were characterized.

152 lymphocytes developed severe swelling of the hind paws when infected with B. burgdorferi.

153 erkeratotic calluses on Krt16(-/-) front and hind paws, which severely compromise the animals' abilit

154 or rat glabrous skin blood perfusion in both hind paws, while a simultaneous heart rate (HR) and DRRs

155 ts were injected subcutaneously in the right hind paw with (99m)Tc-SPIONs (25-50 MBq, approximately 0

156 bar (L5)-DRG induced hyperalgesia in the rat hind paw with a profile similar to that of intraplantar

157 inal cord, rats displayed markedly decreased hind paw withdrawal thresholds, indicative of below-leve

158 esic responses to thermal stimulation of the hind paw without alterations in rearing behavior or body