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1                                         This histaminergic action appears to be mediated by the H(2)
2   Here we examined the modulatory effects of histaminergic agents on the release of amino acid neurot
3 eviewed the early signaling events following histaminergic and cholinergic activation, the identifica
4 recent findings regarding the involvement of histaminergic and gamma-aminobutyric acidergic mechanism
5 seful anti-pruritic therapeutic approach for histaminergic and non-histaminergic pruritus.
6 eptide that was shown to play a role in both histaminergic and nonhistaminergic itch in mice.
7 eptor, and this enables H3Rs to modulate the histaminergic and other neurotransmitter systems.
8  responses of spinothalamic tract neurons to histaminergic and, for the first time, nonhistaminergic
9 s noradrenergic, dopaminergic, serotonergic, histaminergic, and cholinergic neurons.
10 c, glutaminergic-GABAnergic, serotoninergic, histaminergic, and cholinergic systems.
11 MP-independent agonists such as cholinergic, histaminergic, and purinergic agonists that stimulate CF
12 re disease, inducible urticarias, idiopathic histaminergic angio-oedema without weals as a presentati
13                                              Histaminergic angioedema generally presents with urticar
14 millary nucleus, the source of the ascending histaminergic arousal system.
15 ion in the caudate-putamen and neocortex of "histaminergic" axonal projections from the TMN evoked to
16                                              Histaminergic axons broadly innervated every visual regi
17           The breadth of the distribution of histaminergic axons ensures that virtually all levels of
18          Mammalian retinas are innervated by histaminergic axons that originate from perikarya in the
19                       Synaptic inhibition of histaminergic cells by GABA(A) receptors, however, was e
20 also known as Arntl or Mop3) clock gene from histaminergic cells removes this variation, producing hi
21 mine, compound 48/80, endothelin-1), not non-histaminergic (chloroquine) pruritogens in Trpv4 keratin
22                      Ipsi- and contralateral histaminergic compound eyes are required for photic entr
23  involved processes such as mitochondrial or histaminergic disfunction, immunity or neural signalling
24         These results indicate a significant histaminergic effect on LGN thalamocortical cells, with
25 that sedation by clozapine results from anti-histaminergic effects, we show that H1 histamine recepto
26 culate nucleus (PGN), which is innervated by histaminergic fibers from the tuberomammillary nucleus o
27 localized with HDC expression in a subset of histaminergic gastric mucosal cells.
28 acid secretion is mediated via activation of histaminergic, gastrinergic, and cholinergic pathways co
29         SIB-1553A showed modest affinity for histaminergic (H3) and serotonergic (5-HT1 and 5-HT2) re
30 dition SIB-1553A also exhibits affinities to histaminergic (H3) and serotonergic (5-HT1 and 5HT2) rec
31                                              Histaminergic (HA) neurons, found in the posterior hypot
32 pansion in neuronal subpopulations including histaminergic (Hdc), arginine vasopressin/retinoic acid
33 ttenuated scratching behavior in response to histaminergic (histamine, compound 48/80, endothelin-1),
34 nd/or REM-off neurons may not be exclusively histaminergic in rats.
35 otassium (GIRK) channel inhibitor, abolishes histaminergic inhibition of MCH neurons.
36  neurons in other brain regions that receive histaminergic innervation and participate in the express
37  histamine-containing axons reveals striatal histaminergic innervation by the second postnatal week,
38 optic nucleus (VLPO), which receives a dense histaminergic innervation from the tuberomammillary nucl
39 millary nucleus (TMN) is the major source of histaminergic innervation of the mammalian brain and is
40           However, little is known about the histaminergic innervation of visual areas, or the histam
41 ctivity modulates astrocyte responses to non-histaminergic inputs by inducing lasting changes in astr
42 ggest that previously characterized GABA and histaminergic interneurons regulate olfactory input by s
43  mast cell activation via Mrgprb2 evoked non-histaminergic itch in mice independently of the IgE-Fc e
44     However, therapies aimed at blocking the histaminergic itch pathway have been largely ineffective
45 s a pruriceptor-TRP in skin keratinocytes in histaminergic itch, a novel basic concept with translati
46 is a neuropeptide in sensory neurons for non-histaminergic itch, and GRP sensory neurons are dedicate
47 GRP) functions as a neurotransmitter for non-histaminergic itch, but its site of action (sensory neur
48 in sensory neurons results in attenuated non-histaminergic itch, without impairing histamine-induced
49  commonly report experiencing an intense non-histaminergic itch.
50  optimizing current therapies, repositioning histaminergic ligands for new therapeutic uses, or even
51 fy the retrieval of emotional memory; hence, histaminergic ligands might reduce dysfunctional aversiv
52 ance of adverse effects, or repositioning of histaminergic ligands.
53 ation of central alpha2-adrenergic or the H2 histaminergic-like receptors.
54 models, including the acute cheek model, the histaminergic model, and a chronic itch model.
55              During vestibular compensation, histaminergic modulation of glycine and GABA release may
56                                  More potent histaminergic modulators may be required to elucidate th
57                                  We measured histaminergic neuron activity in the dorsomedial, ventro
58 nd female zebrafish brain and quantified the histaminergic neuron numbers.
59       In this study we visualized the entire histaminergic neuron population in adult male and female
60                                              Histaminergic neurones of the dorsomedial tuberomammilla
61             Previous studies have shown that histaminergic neurones of the tuberomammillary nucleus p
62          These results suggest that afferent histaminergic neurones show increased activity during pr
63 twork architecture of two pairs of ascending histaminergic neurons (AHNs) in Drosophila, which functi
64        Many regions of the CNS are devoid of histaminergic neurons [11, 12], raising the possibility
65             Noradrenergic, serotonergic, and histaminergic neurons are continuously active during wak
66                                              Histaminergic neurons are exclusively located in the hyp
67                                              Histaminergic neurons are silent during sleep, and start
68                                     Yet most histaminergic neurons contain GABA.
69                       At the cellular level, histaminergic neurons deficient in synaptic GABA(A) rece
70                          Removing BMAL1 from histaminergic neurons does not, however, affect circadia
71                             Thus wake-active histaminergic neurons generate a paracrine GABAergic sig
72    Surprisingly, GABAergic transmission onto histaminergic neurons had no effect in regulating the na
73                                      The new histaminergic neurons in aging zebrafish brain may arise
74                             There were 40-45 histaminergic neurons in both male and female zebrafish
75                  This surprising increase in histaminergic neurons in narcolepsy may be a compensator
76 low in patients with narcolepsy, we examined histaminergic neurons in patients with narcolepsy and in
77 ulating levels of histidine, which activates histaminergic neurons in the hypothalamus and stimulates
78  also receives modulatory afferents from the histaminergic neurons in the hypothalamus which exhibit
79 OX2Rs eliminates orexin-evoked excitation of histaminergic neurons in the hypothalamus, which gate no
80   In primates the retina receives input from histaminergic neurons in the posterior hypothalamus that
81 rld primates, the retina receives input from histaminergic neurons in the posterior hypothalamus.
82 ibution of one putative local clock in mouse histaminergic neurons in the tuberomamillary nucleus to
83                                              Histaminergic neurons in the tuberomammilary nucleus (TM
84                                              Histaminergic neurons in the tuberomammillary nucleus (T
85                              The activity of histaminergic neurons in the tuberomammillary nucleus (T
86     Further, we identified cotransmitters of histaminergic neurons in the ventrocaudal hypothalamus,
87  inhibition of the MCH system by wake-active histaminergic neurons may be responsible for silencing M
88       In both experiments, Fos expression in histaminergic neurons of all three TMN subnuclei was hig
89                                              Histaminergic neurons of the tuberomammillary nucleus (T
90                                              Histaminergic neurons of the tuberomammillary nucleus (T
91  These "REM-off" neurons were proposed to be histaminergic neurons of the tuberomammillary nucleus (T
92   One key target of the orexin system is the histaminergic neurons of the tuberomammillary nucleus (T
93 esicular GABA transporter (vgat, SLC32A1) in histaminergic neurons produced hyperactive mice with an
94 Dyn inputs to the VLPO, whereas hypothalamic histaminergic neurons provide EM1 inputs to the VLPO.
95        We examined how GABAergic inputs onto histaminergic neurons regulate this behavior.
96                        Finally, we show that histaminergic neurons surround th2-expressing neurons in
97               These results demonstrate that histaminergic neurons throughout the TMN are wake-active
98                                We identified histaminergic neurons using immunostaining for histidine
99                         GABA(B) receptors on histaminergic neurons were dispensable for all behaviors
100                   Increases in the number of histaminergic neurons were paralleled by matching increa
101                    Similarly, because of the histaminergic neurons' key hub-like place in the arousal
102 ding mast cells (MCs), basophils, platelets, histaminergic neurons, and enterochromaffin cells produc
103 mine receptor agonists reduced the number of histaminergic neurons.
104 ma is associated with a marked loss (41%) of histaminergic neurons.
105 larly interfered with the development of the histaminergic neurons.
106 ems and is particularly highly innervated by histaminergic neurons.
107 loss of consciousness by acting primarily at histaminergic neurons.
108  in the ventrocaudal hypothalamus around the histaminergic neurons.
109  and hypothalamic (tuberomammillary nucleus) histaminergic-neurons of gamma2I77 mice were made select
110 anxiety in the interpretation of the role of histaminergic neurotransmission in cognitive function.
111 data from model systems, point to a role for histaminergic neurotransmission in the mechanism and mod
112  These findings reveal the essential role of histaminergic neurotransmission to provide the brain wit
113 kers showed dense innervation of the VLPO by histaminergic, noradrenergic, and serotonergic fibers.
114 sm of action is not attributable to its anti-histaminergic or anti-muscarinic activity, but rather, s
115  of RMP-7 were shown to occur independent of histaminergic or hypotensive mechanisms.
116                    In contrast, cholinergic, histaminergic, orexinergic, and serotonergic wake neuron
117 e required to elucidate the possible role of histaminergic pathways in human obesity.
118 uced itch requires both nonhistaminergic and histaminergic pathways, which are likely relayed by GRPR
119 hese results support the hypothesis that the histaminergic/peptidergic IV neurons are projection neur
120 how considerable projection specificity, the histaminergic projection exhibited great homogeneity.
121            Here, we present the actions of a histaminergic projection neuron on the rhythmically acti
122 f mitogen-activated protein kinase, ERK, for histaminergic pruritogens.
123 y on TRPV4 for calcium influx in response to histaminergic pruritogens.
124 erapeutic approach for histaminergic and non-histaminergic pruritus.
125 amine receptor agonist, SKF38393, and the H2 histaminergic receptor agonist, ranitidine, also hindere
126 ic receptor antagonist, SCH23390, and the H2 histaminergic receptor antagonist, ranitidine, also hind
127 pears to be mediated by the H(2) subclass of histaminergic receptors and inhibits the single-spike ac
128 ta-noradrenergic, D1/D5-dopaminergic, and H2-histaminergic receptors therein.
129 cyclase with forskolin or activation of H(2)-histaminergic receptors with histamine.
130 ation of central alpha2-adrenergic and/or H2-histaminergic receptors, but not via activation of I1-im
131 use represents a valuable model for studying histaminergic regulation of a variety of behaviors and n
132 myocytes by facilitating beta-adrenergic and histaminergic responses.
133 sensitivity involved a minor contribution of histaminergic/serotonergic receptors, but significant ac
134 to evaluate the effect of AMN+LEP on central histaminergic signaling in lean and obese rats.
135 rain plasticity in both the structure of the histaminergic system and its functions induced by altere
136                                          The histaminergic system appears to strengthen central trans
137        Hence, our findings indicate that the histaminergic system comprises parallel, coordinated pat
138 utic uses, or even including agonists of the histaminergic system in the treatment of different patho
139 tal information for the understanding of the histaminergic system in the zebrafish.
140   We found that in psen1(-/-) zebrafish, the histaminergic system is altered throughout life.
141                                          The histaminergic system is involved in basic physiological
142                                          The histaminergic system is involved in the control of arous
143 first report that the integrity of the brain histaminergic system is necessary for long-term, but not
144 e, we report that the integrity of the brain histaminergic system is necessary for retrieval of inhib
145                                Targeting the histaminergic system may modify the retrieval of emotion
146 t increased activity in the tuberomammillary histaminergic system may play a functional role in dampe
147   We investigated the effects of the central histaminergic system on afferent sensory signals in the
148 to demonstrate the modulatory actions of the histaminergic system on neurotransmission in the vestibu
149 ng sensory input may be one way in which the histaminergic system plays a role in arousal.
150 the role of psen1 in plasticity of the brain histaminergic system using a novel psen1 mutant zebrafis
151  Modulatory neurotransmitters, including the histaminergic system, are essential in mediating cogniti
152                Diabetes perturbs the retinal histaminergic system, causing increases in histidine dec
153             Recent studies indicate that the histaminergic system, which is critical for wakefulness,
154 drome (TS) in relation to alterations in the histaminergic system.
155 and that of dopaminergic, noradrenergic, and histaminergic systems in both structures in the consolid
156 These data suggest that the dopaminergic and histaminergic systems in H. americanus appear relatively
157 cant changes of dopaminergic, GABAergic, and histaminergic systems in selective brain areas.
158 s were recorded within the boundaries of the histaminergic TM, however, not all waking-related and RE
159 he latter finding makes it unlikely that the histaminergic TMN has a central role in anesthesia.
160 o controls, narcolepsy patients had 94% more histaminergic TMN neurons (233,572 +/- 49,476 vs 120,455
161                     Similarly, the number of histaminergic TMN neurons was increased 53% in orexin li
162 he cell bodies and proximal dendrites of the histaminergic TMN.
163                       Central nervous system histaminergic tone is thought to play a role in appetite
164 eased sleep need, and therapies that enhance histaminergic tone may improve arousal after head trauma
165 ng of another monosynaptic input to SON, the histaminergic tuberomammillary nucleus (TM) projection,
166 ons to waking/arousal-related neurons in the histaminergic tuberomammillary nucleus (TM), the noradre
167 inergic lateral hypothalamic area [LHA], and histaminergic tuberomammillary nucleus [TMN]).
168 ng in NPY but not dopaminergic neurons), the histaminergic tuberomammillary nucleus and in cholinergi
169 pothalamic systems, but the integrity of the histaminergic tuberomammillary nucleus, a major arousal-
170 s such as the noradrenergic locus coeruleus, histaminergic tuberomammillary nucleus, serotoninergic r

 
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