コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 hibited a 13-fold preference for lysine over histidine.
2 ational change of the conserved neighbouring histidine.
3 ty for SETD3 and inhibited SETD3 activity on histidine.
4 ess is known about other amino acids such as histidine.
5 an affordable linker prepared from natural l-histidine.
6 idazole propionate biosynthesis from dietary histidine.
7 a clear reporter of the protonation state of histidine.
8 central metal cofactor coordinated by three histidines.
9 amino acid residues containing two conserved histidines.
10 eract with and bind Zn(2+) via the essential histidines.
11 rises six K-segments, each with two adjacent histidines.
12 atically via pH-dependent protonation of the histidines.
13 ed environmental changes surrounding residue histidine 266 of POT1 that were dependent on telomere ss
17 These results point to dual functions of histidine-43 in structurally assisting the proper coupli
18 paramagnetic resonance analyses to establish histidine-43 of Methanosarcina acetivorans NifB (MaNifB)
19 for cofactor maturation upon substitution of histidine-43 with alanine; whereas x-ray absorption spec
20 ates of the de novo syntheses of purines and histidine, 5-aminoimidazole-4-carboxamide-1-beta-D-ribof
22 sing the region around KRAS-specific residue histidine 95 at the helix alpha3/loop 7/helix alpha4 int
23 face is characterized by the movement of the histidine 98 residue, which is, after acidification, dec
24 ons in amphipathic character associated with histidines affect the permeabilization properties of p1
26 beta-CASP domains and a cluster of conserved histidine and aspartate residues capable of binding two
29 site-directed mutants identifies a catalytic histidine and how the acceptor site of UGT76G1 achieves
30 vitamin D(3), vitamin C, trytophan, taurine, histidine and hydroxyproline were below the reference ra
31 opic and structural characterization of this histidine and surrounding H-bonding residues, based on a
32 e two target nitrogen atoms-the N(3) atom of histidine and the terminal e-amino nitrogen of lysine-oc
34 sheet and interactions of its dual HxT motif histidines and threonines with phosphate in the active s
38 imilar in GB to basic amino acids lysine and histidine, and phosphatidic acid and phosphatidylglycero
39 ntaining combinations of cysteine, tyrosine, histidine, and serine residues react with octafluorocycl
42 member-specific metabolic bottlenecks (e.g. histidine- and transport-related reactions) and compensa
43 ongly inhibited at pH 6.0 when the conserved histidines are partially charged and H17 is predominantl
44 tidine) and anserine (beta-alanyl-3-methyl-l-histidine) are abundant peptides in the nervous system a
49 d tripeptide stretches that contain multiple histidines associate negatively with crystallizability.
50 366 (L366H) can interact with the introduced histidine at position 370 (stabilizing that portion of t
52 o identify candidate genes for a reaction in histidine biosynthesis lacking an annotated gene and hig
54 IB 3610 cells revealed that genes from the L-histidine biosynthetic pathway, the purine, pyrimidine d
58 behavior of Deionized (DI) water and 10mM L-Histidine buffer solution which were subjected to drop s
59 ophan, phenylalanine + tyrosine, isoleucine, histidine, but limiting for lysine, leucine, and threoni
63 NKD HisC cores co-aggregate with a conserved histidine cluster within Axin, to destabilize it along w
66 ZnO@PLP and ZnO@Py showed good linearity to histidine concentration from 2.49 to 24.4 muM and 7.44 t
68 immunofluorescence microscopy to identify a histidine-containing motif ((398)HTH) in the first extra
69 vity can be controlled through the number of histidine-containing networks and the strength of the su
70 However, after synthesizing a C2-deuterated-histidine-containing peptide, we were able to follow the
72 n (IgV)-like domain and extraordinarily high histidine content, suggesting that unique structural fea
73 spectra indicate that removal of the second histidine converted the protonation and tautomeric equil
75 rrangement that involves a co-axial tyrosine/histidine coordination strategy and a complex electronic
76 HA using an anti-HA antibody and a probe for histidine decarboxylase (HDC), a synthetic enzyme for HA
79 ss-related arousal states, is synthesized in histidine decarboxylase-expressing hypothalamic neurons
80 eries that synthesize two "genes", e.g., the histidine-dependent DNAzyme g1 and the Zn(2+)-ion-depend
81 but whether the Hut system is important for histidine-dependent energy generation or vertebrate colo
83 atients and controls did not differ in their histidine dietary intake, the elevated levels of imidazo
84 We show that simultaneous mutation of these histidines drastically weakens the cis interaction and e
87 measures, participants consumed encapsulated histidine for 4 wk followed by a 3-wk recovery period.
88 tible indispensable AA (IAA) score was 1.03 (histidine) for WPI and close to 0 for zein, owing to its
89 acteria to synthesize; therefore, scavenging histidine from the environment is likely advantageous.
90 se, the highly prevalent FcgammaRIIa (CD32a) histidine (H)-131 variant (CD32aH) is strongly linked to
93 t-shifted resonances tentatively assigned to histidine Hdelta1 display a two-state chemical exchange
96 xylate group of 2OG is trans to the proximal histidine (His134) of the 2-His-1-carboxylate facial tri
97 the C1 carboxylate group trans to the distal histidine (His211); (2) The decay rate constant of the f
98 e processes reflect the rotational motion of histidine imidazole rings that coordinate the coppers in
100 duct complex, SETD3 generates the methylated histidine in an N(1)-protonated (N(1)-H) and N(3)-methyl
101 method for the determination of the pK(a) of histidine in complex or heterogeneous systems amenable t
102 g the nepenthesin loop of plasmepsin V and a histidine in place of a catalytic aspartate in plasmepsi
103 duced by bacteria through decarboxylation of histidine in spoiled foods such as fish is known to caus
104 These results suggest that bioavailable histidine in the lung promotes Acinetobacter pathogenesi
105 ressing the alpha-chain segment TRAV9-2 or a histidine in their alpha- or beta-chain complementarity
106 rleucine (HHL), but only from species with a histidine in their alpha1(I) C-telopeptide sequence.
107 HutH is required for acquiring nitrogen from histidine in vitro, and strains inactivated for hutH are
110 e demonstrate here that two highly conserved histidines in the C-terminal domain of PrP(C) are essent
111 ssays and cysteine accessibility placed both histidines in the extracellular half of the cytoplasmic
113 ues from I360 to F370 in the S4 segment into histidine, in i, i + 3 and i, i + 6 or i, i + 4 and i, i
114 lementation; however, the clinical safety of histidine intake above the average dietary intake (1.52-
116 etal ion bridges, and we have found that the histidine introduced at position 366 (L366H) can interac
121 e or pentacoordinate, depending on whether a histidine is coordinating or not at the sixth position o
124 requires the presence of a group III hybrid histidine kinase (HHK) and the high osmolarity glycerol
125 ponent systems (TCS) which comprise a sensor histidine kinase (HK) containing a phosphorylatable cata
126 ed approach to disrupt a subset of cytokinin histidine kinase (HK) receptors in rice (Oryza sativa) i
130 s by sensing the accumulation of AIP via the histidine kinase AgrC and the response regulator AgrA.
131 tion pathway is conserved in Shewanella, and histidine kinase and flagella-mediated motility are esse
133 ospho-signalling proteins, the transmembrane histidine kinase CckA and the cytoplasmic phosphotransfe
134 ges from a strict linear organization of the histidine kinase CheA in Treponema denticola cells, whic
136 ing increases the autophosphorylation of the histidine kinase CheA2, followed by CheY2-mediated depho
137 n transporter PiaA, or competence regulatory histidine kinase ComD significantly decreased transmissi
138 Bioinformatics analysis showed that the SrrB histidine kinase contains several domains, including an
140 G antagonizes the bacterial receptor QseC, a histidine kinase encoded within the core Enterobacteriac
141 en sensor protein AfGcHK is a globin-coupled histidine kinase in the soil bacterium Anaeromyxobacter
142 tation and computation we here show that the histidine kinase is activated by piston-like displacemen
143 AI-2 also binds to the dCACHE domains of histidine kinase KinD from Bacillus subtilis and diguany
144 mutations in bfmS, which encodes the sensor histidine kinase of the BfmRS two-component system (TCS)
146 and ground-state dynamics of the UV form of histidine kinase rhodopsin 1 (HKR1) from eukaryotic alga
150 gain-of-function mutations in the essential histidine kinase WalK, which also elevates expression of
151 nt derivatives lacking the chemotaxis master histidine kinase, CheA4, or the central response regulat
156 been demonstrated to occur by their cognate histidine kinases but also by low molecular weight phosp
157 ivity and localization of two key regulatory histidine kinases that control cell fate and differentia
161 Cu(A) site of Pseudomonas stutzeri N(2)OR, a histidine ligand was found to undergo a conformational f
162 uestion in this field is how the function of histidine ligated Cu centers are modulated by delta vs e
167 This study suggests that perturbations in histidine metabolism selectively target neural tumours t
168 support the broader hypothesis that protein histidine methylation acts as a common regulatory mechan
170 -scale CRISPR screens, we identify the actin histidine methyltransferase SET domain containing 3 (SET
174 through traditional, vertically adsorbed, or histidine-modified peptides, such a molecularly tunable
175 ) in addition to NH(4) (+) Of note, the twin-histidine motif was not essential for ammonium transport
176 ystematic replacements in the conserved twin-histidine motif, a hallmark of most AMT/Mep/Rh, alter su
178 erved in translocases, and a family-specific histidine near motif IVa, reminiscent of the "arginine c
179 idues in outer capsid proteins, a pH-sensing histidine of a zinc finger within the receptor-binding V
180 hydrogen-bonding interaction with the target histidine of actin that likely contributes to its >1300-
182 with PD-L1 did the FSY react with a proximal histidine of PD-L1 selectively, enabling irreversible bi
183 a heme cofactor is allowed to bind to either histidine or cysteine ligands, within a single artificia
186 yphosphate phosphatases (MINPPs) are clade 2 histidine phosphatases (HP2P) able to carry out the step
190 t genome revealed, uniquely among mammals, a histidine point variation in the neuronal potassium-chlo
191 addition, changing ANDV residue S386 to the histidine present in MAPV N or the alanine present in ot
192 the enolate intermediate is protonated by a histidine preventing CO(2)-enolate recombination, yieldi
193 arbonyl- and trityl-protected, C2-deuterated histidine produces a vibrational-probe-equipped amino ac
194 This biosensor can be used to isolate L-histidine-producing strains by FACS, showing that TR eng
195 ction of a NME1 site-directed mutant lacking histidine protein kinase activity but retaining nucleosi
197 mal pH could relax the frustration, allowing histidine protonation and facilitating conformational co
200 reinforced following protonation of a nearby histidine, providing a conceptual link between receptor
202 ed and hydrogen-bonded imidazole-imidazolium histidine quaternary structures have been proposed, base
206 l reactivity that is conveyed by a conserved histidine residue and allows conjugation to cell surface
207 to demonstrate that both a C-terminal domain histidine residue and the 2-amino group of OG base are c
208 ce of RIPK1 activation, suggesting that this histidine residue functions as a proton acceptor to modu
210 entially autophosphorylate at each conserved histidine residue in the individual protomers, leading t
212 domains contribute equatorially coordinated histidine residue side-chains, resulting in a novel brid
213 diphosphate (ADP)-ribosylation of a modified histidine residue, diphthamide, at His715, which blocks
217 subjects, while the extents of conversion of histidine residues at alpha-His-20, alpha-His-50, and be
219 conformational change removes one of the two histidine residues from the active site, likely triggeri
220 rmational changes by precisely preorganizing histidine residues in buried hydrogen-bond networks.
222 he receptor-binding VP2 protein, and certain histidine residues in the membrane-penetrating VP5 prote
223 ted mZIP4 variants, we provide evidence that histidine residues in this motif coordinate a zinc ion i
224 microscopy, revealing that highly-conserved histidine residues near the C terminus of each microtubu
227 of interest and inspired by nature's use of histidine residues within the active sites of various co
228 trate that the highly conserved cysteine and histidine residues within the C-X(8)-C-X(24-75)-H-X-G-G-
229 tion through protonation of CpxA periplasmic histidine residues, and upregulates the fabA and fabB ge
230 ted CC' loop and a striking concentration of histidine residues, located in the complementarity-deter
234 species that lack an alpha1(I) C-telopeptide histidine, revealed that HHL is a laboratory artifact ra
235 w that TaHRC, a gene that encodes a putative histidine-rich calcium-binding protein, is the key deter
237 to associate predominantly with albumin and histidine-rich glycoprotein (HRG) in mouse and human pla
238 a rapid diagnostic tests (mRDTs) that target histidine-rich protein 2 (HRP2) are important tools for
239 control and elimination, and Haiti relies on histidine-rich protein 2 (HRP2)-based rapid diagnostic t
241 at detect the Plasmodium falciparum-specific histidine-rich protein 2 (PfHRP2) antigen are the primar
242 uency of Plasmodium falciparum isolates with histidine-rich protein 2 (pfhrp2) gene deletion as one o
244 While many divalent metals bind to poly histidine sequences reversibly, oxidation of imidazole-b
245 promotes Acinetobacter pathogenesis and that histidine serves as a crucial nitrogen source during inf
246 n N-terminal histidine and a second internal histidine side chain in a configuration called the histi
247 ime scales, with coupling of the dynamics of histidine side chains and those of remote key backbone e
249 wide measurements of mRNA translation during histidine starvation in fission yeast Schizosaccharomyce
251 and n = 20 women) and/or a 16-g/d dosage of histidine (Study 2, n = 21 men and n = 19 women); 27 par
252 vely low domain mobility, and associated the histidine substrate and docking domains with the kinase
253 C/D- and G/H-turn regions hosting the three histidines, suggest a complex way of pH-governed alloste
254 lts aged 21-50 y completed graded dosages of histidine supplement (4, 8, and 12 g/d, Study 1) (n = 20
256 o acid with health benefits that may warrant histidine supplementation; however, the clinical safety
258 ted PfCSP4/38, was produced initially with a histidine tag and purified by a simple two-step procedur
262 nickel-binding motifs: a variable C-terminal histidine tail and a strictly conserved H(W/F)X (2)HX (3
263 , we generated an actin variant in which the histidine target of SETD3 was substituted with methionin
264 imidazole hydrogen-bonding geometries in the histidine tetrad at low pH, thus validating the proton c
266 racting and binding Zn(2+) via the essential histidines than the monomer or a dimer with the histidin
268 ue pairing of an arginine with the catalytic histidine that makes the proteolytic activity of GII.4 p
269 otein motif (pfam10520) with eight conserved histidines that is shared by an alternative type of plan
270 egatively regulated by arginine, lysine, and histidine, the amino acids that PQLC2 transports across
272 were able to follow the protonation state of histidine throughout a pH titration using Raman differen
273 in sites of Met, His, and Tyr, conversion of histidine to aspartate and hydroxyaspartate was identifi
274 hydrophobic interaction with cell membranes, histidine to facilitate endosomal escape and cysteine fo
277 To our knowledge, this advanced oxidation of histidine to hydroxyaspartate is a new post-translationa
280 The amino acid mutation at position 84 from histidine to threonine minimizes the mitogenicity of the
285 hen randomly assigned to static storage with histidine-tryptophan-ketoglutarate (HTK) at 4 degrees C
286 ) after 0, 4, and 8 hours of cold storage in histidine-tryptophan-ketoglutarate preservation solution
287 or indica germplasms identified rice Lysine-Histidine-type Transporter 1 (OsLHT1) as a candidate gen
288 ttributed to the protonation of the bridging histidine upon copper reduction, yielding redox centers
291 vel protocol to measure transporter-mediated histidine uptake, system L amino acid transporter activi
292 We previously identified the A. baumannii histidine utilization (Hut) system as being linked to nu
294 ingly, both zinc and copper addition shifted histidine UVRR bands in a manner diagnostic for metal co
297 trostatic and hydrophobic characteristics of histidine were both required for tau-microtubule binding
299 ng a phenylalanine that replaces a conserved histidine, which in typical DSORs is essential for stabi