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1 solic lysine deacetylase activated by mDia - histone deacetylase 6.
2 a, MYC, bromodomain-containing protein 4 and histone deacetylase 6.
4 acetylation, we pharmacologically inhibited histone deacetylase 6, a known deacetylase of Hsp90, or
5 DJ-1 serves as a signal for interaction with histone deacetylase 6, an adaptor protein that binds the
7 TR) mutant CFTRDeltaF508 and associates with histone deacetylase 6 and dynein, proteins required for
8 sh1 reprogramming is dependent on functional HISTONE DEACETYLASE 6 and methyltransferase MET1, and tr
10 ts, together with observations on changes in histone deacetylases 6 and tubulin modifications in the
11 ession of the cytoplasmic deacetylase HDAC6 (Histone Deacetylase 6) and that FGFR3 accumulation is co
12 eases INF2 inhibition, whereas inhibitors of histone deacetylase 6 block the activation of cellular I
13 zation was rescued by inhibition of ROCK and histone deacetylase 6 but not by a GAP-mutant form of AR
14 Additionally, a complex of PRR9, TPL, and histone deacetylase 6, can form in vivo, implicating thi
15 .15 angstrom-resolution crystal structure of histone deacetylase 6 cocrystallized with SelSA-2 conclu
16 he death inducer-obliterator (dido) gene, in histone deacetylase 6 delivery to the primary cilium.
18 t a specific subset of RdDM targets requires HISTONE DEACETYLASE 6 (HDA6) acting upstream of Pol IV r
20 d with increased Aurora kinase A (AURKA) and histone deacetylase 6 (HDAC6) activities, which drive di
21 a promoting MT polymerization and inhibiting histone deacetylase 6 (Hdac6) activity to increase MT ac
23 in up-regulation of the tubulin deacetylase histone deacetylase 6 (HDAC6) and altered spatial distri
24 involves protein kinase C alpha (PKCalpha), histone deacetylase 6 (HDAC6) and beta-catenin (beta-cat
27 ssion of two known microtubule deacetylases, histone deacetylase 6 (HDAC6) and Sirtuin T2 (SirT2), in
28 e network by a protein complex consisting of histone deacetylase 6 (HDAC6) and the dynein motor compl
29 Here, we have observed that the levels of histone deacetylase 6 (HDAC6) and the related family mem
30 s, SGs can sequester the proteostasis factor histone deacetylase 6 (HDAC6) and thereby impede TDP-43
34 e, we report that the microtubule-associated histone deacetylase 6 (HDAC6) differentially regulates a
35 esults in loss of these pathways and gain of histone deacetylase 6 (HDAC6) expression and activity.
37 bulin deacetylases sirtuin 2 (Sirt2) and the histone deacetylase 6 (HDAC6) has been associated with t
43 l inhibition as well as genetic silencing of histone deacetylase 6 (HDAC6) increase alpha-tubulin ace
44 s research that demonstrates the efficacy of histone deacetylase 6 (HDAC6) inhibition in a genetic ca
47 stat was recapitulated using the cytoplasmic histone deacetylase 6 (HDAC6) inhibitor tubacin, reveali
52 c acid were merged into tertiary amide-based histone deacetylase 6 (HDAC6) inhibitors to develop mult
76 find that the centrosome-associated protein histone deacetylase 6 (HDAC6) promotes the polyubiquitin
80 ted by the ubiquitin-proteasome pathway, and histone deacetylase 6 (HDAC6) serves as an ubiquitin E3
82 ate in the cytoplasm and are transported via histone deacetylase 6 (HDAC6) toward the aggresomes.
83 iting the microtubule-associated deacetylase histone deacetylase 6 (HDAC6) via a signaling pathway in
84 d siRNA validation, we found that inhibiting histone deacetylase 6 (HDAC6) was cardioprotective at th
87 ype by promoting changes in the stability of histone deacetylase 6 (HDAC6) with concomitant defects i
89 so requires input from host microtubules and histone deacetylase 6 (HDAC6), a cytosolic enzyme that,
90 Moreover, GRP94 is acetylated and binds to histone deacetylase 6 (HDAC6), a known deacetylase and a
92 mpaired in Drosophila melanogaster, and that histone deacetylase 6 (HDAC6), a microtubule-associated
93 ignificant microarray hits was the cytosolic histone deacetylase 6 (HDAC6), a regulator of cell migra
94 of stress responses, we examined the role of histone deacetylase 6 (HDAC6), a unique member of the HD
95 of the tubulin deacetylases, sirtuin 2, and histone deacetylase 6 (HDAC6), blocks EC tube formation
97 servations that tau is a direct substrate of histone deacetylase 6 (HDAC6), we sought to map all HDAC
98 e microtubules with paclitaxel or inhibiting histone deacetylase 6 (HDAC6), which destabilizes microt
99 1 inhibits the interaction between TPPP1 and histone deacetylase 6 (HDAC6), which in turn results in
100 ively regulates alternative splicing through histone deacetylase 6 (HDAC6)-mediated deacetylation of
101 blockage of the autophagy flux resulted from histone deacetylase 6 (HDAC6)-mediated microtubule desta
102 RelA in the nucleus, by which MIIP prevents histone deacetylase 6 (HDAC6)-mediated RelA deacetylatio
113 ompanied by MT destabilization and increased histone deacetylase-6 (HDAC6) activity resulting from el
115 identify the ubiquitin-binding deacetylase, histone deacetylase-6 (HDAC6), as a central component of
118 attenuate NF-kappaB signaling, and recruits histone deacetylases-6 (HDAC6) to p300-marked promoters
120 Jun dimerization protein 2 [JDP2], ATF2, and histone deacetylase 6 [HDAC6]), as determined by proteom
121 s and cells treated with ethanol or with the histone deacetylase 6 inhibitor trichostatin A (TSA).
122 ortantly, experimental intervention with the histone deacetylase 6 inhibitor tubastatin A in an ortho
124 cluding DNA methyltransferase inhibitors and histone deacetylase 6 inhibitors (DNMTis and HDAC6is) in
131 eatment of CAP-KAc-actin-inhibited INF2 with histone deacetylase 6 releases INF2 inhibition, whereas
133 resome by promoting an iNOS interaction with histone deacetylase 6, which serves as an adaptor betwee