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1 tive product 2,5-dihydroxyphenylacetic acid (homogentisate).
2  of vitamin E is initiated by prenylation of homogentisate.
3 hat results in aromatic hydroxylated product homogentisate.
4 HPPD to convert 4-hydroxyphenylpyruvate into homogentisate.
5 kaptonuria is an inherited disease caused by homogentisate 1,2-dioxygenase (HGD) deficiency.
6 ecessive disorder caused by mutations in the Homogentisate 1,2-dioxygenase (HGD) gene.
7                                              Homogentisate 1,2-dioxygenase (HGDO) uses a mononuclear
8 or of metabolism caused by the deficiency of homogentisate 1,2-dioxygenase activity.
9 one can reduce HGA production in humans with homogentisate 1,2-dioxygenase deficiency, the long-term
10 e colonies confirming that in the absence of homogentisate 1,2-dioxygenase the intermediary in tyrosi
11 utations in the HGD gene and a deficiency of homogentisate 1,2-dioxygenase, is characterized by accum
12 utations in the HGO gene and a deficiency of homogentisate 1,2-dioxygenase, results in an accumulatio
13     Due to an insertion in hmgA that encodes homogentisate 1,2-dioxygenase, the mutant secreted incre
14  and early termination of translation of the homogentisate 1,2-dioxygenase.
15 is caused byby a complex set of mutations in homogentisate 1,2-dioxygenasegene and consequent accumul
16 Remarkably, two O(2)-dependent dioxygenases, homogentisate-1,2-dioxygenase (HmgA) and 4-hydroxyphenyl
17 and Phe by producing maleylacetoacetate from homogentisate (2,5-dihydroxyphenylacetate).
18 nase the intermediary in tyrosine catabolism homogentisate accumulates and undergoes nonenzymatic oxi
19 ully produced p-hydroxymandelate, along with homogentisate and an unknown compound.
20 bolomic analysis revealed elevated levels of homogentisate and deoxycholate and reduced levels of lac
21 me, it converts p-hydroxyphenylpyruvate into homogentisate and is part of the superfamily of alpha-ke
22 ersion of (4-hydroxyphenyl)pyruvate (HPP) to homogentisate as part of the tyrosine catabolism pathway
23 ncomitant with the formation of the product, homogentisate, based on rapid quench and pre-steady-stat
24                                              Homogentisate binds as a monodentate ligand to Fe(2+), a
25                         We show that reduced homogentisate catabolism in a soybean HGO mutant is an e
26 ch catalyzes the committed enzymatic step in homogentisate catabolism.
27 s the condensation of phytyl-diphosphate and homogentisate, derived from the methylerythritol phospha
28                             GmHGO1 encodes a homogentisate dioxygenase (HGO), which catalyzes the com
29 dy known to be involved in its biosynthesis (homogentisate dioxygenase and hydroxyphenylpyruvate diox
30 We further demonstrated that coexpression of homogentisate geranylgeranyl transferase (HGGT), stacked
31 l synthesis is initiated in monocot seeds by homogentisate geranylgeranyl transferase (HGGT).
32 the same substrates as HMS but forms instead homogentisate (HG).
33 n into 4-hydroxyphenylpyruvate (HPP) to form homogentisate (HG).
34 ersion of (4-hydroxyphenyl)pyruvate (HPP) to homogentisate (HG).
35 ersion of (4-hydroxyphenyl)pyruvate (HPP) to homogentisate (HG).
36 manol ring and a 15-carbon tail derived from homogentisate (HGA) and phytyl diphosphate, respectively
37 cid quench reactions and product analysis of homogentisate indicate that HPPD as isolated is fully ac
38                                   Binding of homogentisate is driven by enthalpy and is entropically
39  course of one turnover the concentration of homogentisate is stoichiometric with enzyme concentratio
40 bicides that target pathways associated with homogentisate metabolism.
41 te5-2 folk plants after supplementation with homogentisate or 1,4-dihydroxy-2-naphthoic acid, respect
42 ynthetic intermediate, whereas vte2 disrupts homogentisate phytyl transferase activity and does not a
43                                              Homogentisate phytyltransferase (HPT) is a key enzyme li
44                                              Homogentisate phytyltransferase (HPT) performs the first
45                    This enzyme is related to homogentisate phytyltransferase (HPT), which catalyzes t
46 hosphate (PDP) catalyzed by a membrane-bound homogentisate phytyltransferase (HPT).
47 we (i) confirmed previous results suggesting homogentisate phytyltransferase as the limiting enzymati
48 ptimized and codon-optimized versions of the homogentisate phytyltransferase vitamin E2 (VTE2) from S
49 a series of single-gene constructs (encoding homogentisate phytyltransferase, tocopherol cyclase, and
50 zyme in tocopherol (vitamin E) biosynthesis, homogentisate phytyltransferase.
51 und degradation, including the metabolism of homogentisate, salicylate and gentisate catabolism, benz
52 hat this mutation results in accumulation of homogentisate that is oxidized and polymerized to produc
53  resolved in a crystal grown anoxically with homogentisate, which was subsequently incubated with dio