コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 e compared to that of beta2 microglobulin, a housekeeping gene.
2 real-time PCR assay specific for a cellular housekeeping gene.
3 he constitutive and ubiquitous activity of a housekeeping gene.
4 2S ribosomal RNA (12S rRNA), a mitochondrial housekeeping gene.
5 glyceraldehyde-3-phosphate dehydrogenase, a housekeeping gene.
6 ce of a 5' CpG island suggest that BIVM is a housekeeping gene.
7 robust upregulation of this highly expressed housekeeping gene.
8 d nucleotides that are often associated with housekeeping genes.
9 ng scheme (MLST) for P. acnes based on seven housekeeping genes.
10 interspersed Tcrd elements and neighbouring housekeeping genes.
11 und in the body of some actively transcribed housekeeping genes.
12 and relies on the sequencing of one or more housekeeping genes.
13 ning regions of gyrA and parC, two essential housekeeping genes.
14 obile genetic elements and also mutations in housekeeping genes.
15 identified as outliers, historic markers, or housekeeping genes.
16 biogenesis and function as well as for many housekeeping genes.
17 ultilocus sequence typing based on bacterial housekeeping genes.
18 ylogeny based on partial sequencing of seven housekeeping genes.
19 RNA (mRNA) expression via GAPDH or 18S rRNA housekeeping genes.
20 on the internal fragment sequences of seven housekeeping genes.
21 or B. burgdorferi based on eight chromosomal housekeeping genes.
22 lated species, including those encoding core housekeeping genes.
23 lines and tissues since both are known to be housekeeping genes.
24 acr2 promoter and indirect effects on major housekeeping genes.
25 eature identified to date for distinguishing housekeeping genes.
26 enetic analysis using sequences of predicted housekeeping genes.
27 ithout causing an outage of transcription of housekeeping genes.
28 elium, genes expressed in neural tissues and housekeeping genes.
29 background of high recombination rates among housekeeping genes.
30 ors, while it had no effect on expression of housekeeping genes.
31 e only a small number of previously reported housekeeping genes.
32 e stress responses with the steady output of housekeeping genes.
33 leus-encoded mitochondrial genes and various housekeeping genes.
34 nted among intracellular and slowly evolving housekeeping genes.
35 e between-array variance in four out of five housekeeping genes.
36 alling have diverged more rapidly than known housekeeping genes.
37 thod is based on the genetic variation among housekeeping genes.
38 oters of numerous tissue-specific as well as housekeeping genes.
39 rates is a consequence of the clustering of housekeeping genes.
40 uencing analysis of antigen, structural, and housekeeping genes.
41 ription in many pathogens; they also control housekeeping genes.
42 er of the HPR1 gene belongs to the family of housekeeping genes.
43 ing c-fos and down-regulating c-myb) but not housekeeping genes.
44 genes, 43% of whose human orthologs are also housekeeping genes.
45 nzymes needed in small amounts and even many housekeeping genes.
46 is also common within constitutively active housekeeping genes.
47 els of promoter SNP density are common among housekeeping genes.
48 contain both spliced and unspliced mRNAs of housekeeping genes.
49 affect expression or polymerase occupancy at housekeeping genes.
50 sistent with previous work employing nuclear housekeeping genes.
51 ormalization across samples using reference (housekeeping) genes.
52 ve chromatin and constitutively transcribed (housekeeping) genes.
53 agent was characterized by sequencing of six housekeeping genes (16S rRNA, ftsZ, gltA, groEL, ribC, a
55 thermore, we present 692 uniformly expressed housekeeping genes, 43% of whose human orthologs are als
56 g copies) and RNA transcripts from the GAPDH housekeeping gene (5.45 ng total mouse embryonic stem ce
57 free CpG island from the human HNRPA2B1-CBX3 housekeeping genes (A2UCOE) effectively prevents transge
58 est, as indicated by local expression of the housekeeping gene acpP and by expression from a constitu
59 s preceded by a cluster of 35 or more tandem housekeeping genes, all of which are transcribed away fr
60 c regions were cloned, revealing a number of housekeeping genes; all were evaluated for their diagnos
61 displays binary behavior, strongly expressed housekeeping genes altered the magnitude of their transc
63 ysis of 1930 pneumococcal genotypes from six housekeeping genes and 94 genotypes from related species
64 erol (gpd1) caused a prolonged repression of housekeeping genes and a delay in gene activation at ind
65 those of four major gastric proteins and two housekeeping genes and comparable to the level of pepsin
67 ence analysis of nucleotide polymorphisms in housekeeping genes and has shown a high degree of intras
68 proteins do not include proteins encoded by housekeeping genes and instead include ABC transporters
69 the 5'-UTR show the most distinction between housekeeping genes and tissue-specific genes in both den
70 an expanded eight gene version based on six housekeeping genes and two 'putative virulence' genes (e
74 ilocus sequence types (ST(M); based on seven housekeeping genes) and four groups of clonally linked (
77 omains of early embryonic development genes, housekeeping genes, and constitutive regulatory elements
78 ranscribed at stable levels, similar to most housekeeping genes, and its transcription is regulated b
80 th polymorphisms at multiple loci (rrn, vcg, housekeeping genes, and repetitive DNA) designated profi
82 reater cell-to-cell variation than that of a housekeeping gene, another induced transcript and viral
83 iminatory power of this MLST method based on housekeeping genes appears to be higher than that of ERI
84 Specifically, SSR densities in 5'-UTRs in housekeeping genes are about 1.7 times higher than those
86 , our analysis reveals that the locations of housekeeping genes are closely associated with cross-tis
87 ly bipartite organization in which conserved housekeeping genes are concentrated in syntenic gene-ric
89 We previously reported that specialized and housekeeping genes are differentially regulated via de n
94 with previous findings, tissue non-specific (housekeeping) genes are short in all gene regions (codin
95 how that mOTUs, which are based on essential housekeeping genes, are demonstrably well-suited for qua
98 DR) approach, which employs stably expressed housekeeping genes as references to eliminate platform-s
99 s-related genes, and are reduced to encoding housekeeping genes as well as a protease subunit (clpP)-
100 ulation of a large number of genes including housekeeping genes as well as actively regulated genes.
101 -UTR, accounts for 74-79% of the tri-SSRs in housekeeping genes, as compared to 42-57% in tissue-spec
102 and IB), atpD (type II), and recA (type III) housekeeping genes, as well as a Fic family toxin gene (
103 11 H. ducreyi loci, including virulence and housekeeping genes, augmenting published data sets with
105 spect to tissue weight or mRNA levels of the housekeeping genes B2M or GAPDH, were over-expressed in
107 ate tissue-specific, co-regulated as well as housekeeping genes based only on their initial proximity
108 ve to either: tissue weight or levels of the housekeeping genes beta-2 microglobulin (B2M) and glycer
109 y MLST based on allelic profiles of the four housekeeping genes (betL, gyrB, pgm, and recA), and 34 a
110 There is evidence of genetic exchange of the housekeeping genes between the two species, but at a ver
111 a set of randomly chosen genes, and a set of housekeeping genes broadly conserved in eukaryotes.
112 levels affect the polyadenylation levels of housekeeping genes, but not of p21 and c-fos genes, whic
114 tes a variety of tissue-specific and general housekeeping genes by recruiting specialized coactivator
116 ployed a novel approach to determine whether housekeeping genes can be distinguished from tissue-spec
118 leotide polymorphism (SNP) approach for nine housekeeping genes, characterizing penA alleles, and ant
121 e groEL gene, and multilocus sequencing of 7 housekeeping genes confirmed the presence of a common st
122 from 69 of the 74 FFPE tissues from which a housekeeping gene could be amplified and was also cost-e
123 the quantification of gene expression using housekeeping genes (cytosolic GAPDH and 18S RNA) as inte
124 subtraction and normalization using a set of housekeeping genes, data were analyzed using Significanc
126 the core promoter -270GC-rich box of PIGM, a housekeeping gene, disrupts binding of the generic trans
127 phylogenetically distinct clusters, whereas housekeeping genes do not, consistent with a recent spre
129 promoter regions of some of the most active housekeeping genes during interphase in human cells, but
130 t than cDNA-RDA at removing highly expressed housekeeping genes during the subtractive hybridization
131 ated the expression levels of four cellular "housekeeping" genes during epithelial differentiation.
132 ly 25% of expressed genes that are essential/housekeeping genes (e.g. RNA synthesis and splicing).
134 ontrolled solely by the promoter of either a housekeeping gene EF-1alpha or the human HLA-DRalpha gen
135 rom positive controls, negative controls and housekeeping genes embedded in the nCounter system.
136 ute and temporal control of the prototypical housekeeping gene encoding the proliferating cell nuclea
137 y resolved phylogenetic signals and that the housekeeping genes evolve differently compared with the
138 e, in wild-type virus-infected cells mRNA of housekeeping genes exemplified by GAPDH is degraded rapi
139 ments of the loci were found to contain both housekeeping genes (expressed during several life-cycle
140 xpression domains in C(3), including typical housekeeping gene expression patterns in various tissues
141 sequences that are enriched in promoters of housekeeping genes, focusing on those DNA sequences whic
143 sults suggest that GMD2 represents the major housekeeping gene for the de novo synthesis of GDP-l-Fuc
145 To search for the internal references, 10 housekeeping genes from a gut transcriptome of a wood-fe
146 n mRNA splicing efficiency, in expression of housekeeping genes from either TATA-containing or TATA-l
147 ely removes highly expressed but nonspecific housekeeping genes from lens tissue expression profiles,
148 hat isochore membership does not distinguish housekeeping genes from tissue-specific genes and that r
149 epetitive sequence environment distinguishes housekeeping genes from tissue-specific genes in every i
152 al activation across cell lines, enriched in housekeeping genes, functionally related to fundamental
154 d subspecies of Salmonella, we analyzed four housekeeping genes, gapA, phoP, mdh and recA, comprising
155 les with more than 2.5 x 10(5) copies of the housekeeping gene GAPDH mRNA (detection sensitivity exce
156 there was no amplification of CRX; only the housekeeping gene (GAPDH) demonstrated amplification.
157 nching holes to deliver cholesterol-modified housekeeping gene (Gapdh) siRNA to the mouse ear skin.
158 ere sex differences in protein levels of the housekeeping gene, GAPDH, cautioning against the use of
159 which dominantly inherited mutations in the housekeeping gene GARS, which encodes glycyl-tRNA synthe
160 -function mutations in the widely expressed, housekeeping gene, GARS The mechanisms underlying select
161 Our data demonstrate that, like sex-linked housekeeping genes, germ-cell-specific sex-linked genes
162 scheme, based on conserved regions of seven housekeeping genes, gltA, gdhB, recA, cpn60, rpoD, gyrB,
164 valuate the suitability of two commonly used housekeeping genes, glyceraldehyde 3-phosphate dehydroge
165 stx(2), rfbE, ehxA, and iha) to that of the "housekeeping" gene gnd during natural human and experime
167 nce of phylogenies based on a representative housekeeping gene (gyrB or pyrH) and a representative lu
168 sis of horizontal transfer by using multiple housekeeping genes (gyrB, recA, and pyrH) and multiple l
169 ilocus sequence typing (MLST) by using three housekeeping genes, gyrB, pgm, and recA; sequence data w
171 sponds to different functional classes, with housekeeping genes having few contacts, and dosage-sensi
174 Diabrotica undecimpunctata howardi (Barber), housekeeping genes (HKG), beta-actin (Actin), beta-tubul
180 such GAPs generated so far bear mutations in housekeeping genes important for parasite development in
182 sequences to evaluate the robustness of this housekeeping gene in the taxonomic placement of the ente
184 y be used for other types of therapeutic and housekeeping genes in endogenous and exogenous stem cell
186 alterations of Creb, ubiquitin-C, and other housekeeping genes in PS-deficient MEFs, indicating tran
187 interacts with transcriptional regulators at housekeeping genes in somatic cells is not well understo
188 s suggest a surprising potential role for a 'housekeeping' gene in fine-tuning the development of an
190 iption start site on many of the most active housekeeping genes, including genes encoding translation
191 o been shown to affect expression of E. coli housekeeping genes, including H-NS, a global regulator t
192 found a number of long SSRs associated with housekeeping genes, including rRNA and tRNA genes, genes
194 nrpa and Rab4b, that have characteristics of housekeeping genes, including ubiquitous expression, clo
199 promoter, consistent with characteristics of housekeeping genes, is highly GC rich and is devoid of a
200 '-flanking region contains the features of a housekeeping gene; it has neither a TATA nor a CAAT box,
201 or, to mechanistically dissect how essential housekeeping genes like TFR1 successfully balance the op
202 ST) in which sequence variations in the MLST housekeeping gene loci are detected by restriction fragm
203 PCR amplification of each of the seven MLST housekeeping gene loci by using the same primer pairs us
204 ately 500- to 600-bp gene fragments of seven housekeeping gene loci, would include the pilA, abcZ, se
207 t locations within a BAC containing the DHFR housekeeping gene locus, we obtain copy-number-dependent
208 e to convergent losses of photosynthesis and housekeeping genes, making them excellent systems for st
209 gesting that chromatin domains may influence housekeeping genes more than tissue-specific genes.
210 , and CRISPR/cas) is its ability to cleave a housekeeping gene mRNA after being activated by a cancer
211 ii) tightly bind a structured fragment of a housekeeping gene mRNA, and iii) cleave it with efficien
212 rates that the concatenated sequences of the housekeeping genes of B. burgdorferi provide highly reso
214 ation patterns of a constitutively expressed housekeeping gene, of a tissue-specific gene, and among
215 , was used to develop a method of predicting housekeeping genes on the basis of DNA sequence alone.
216 or a gene therapy DNA machine that cleaves a housekeeping gene only in the presence of a cancer-causi
218 een focused on investigating the absence of 'housekeeping' genes or components of well-studied pathwa
219 cleotide sequences of multiple loci encoding housekeeping genes, or fragments of them, MLST data are
220 messenger RNA (mRNA) transcripts to MBD4 (a housekeeping gene) (P=0.002), and a 590% higher ratio of
221 on (calculated for each kit as the number of housekeeping gene PCR-positive samples divided by the to
222 CR-positive samples divided by the number of housekeeping gene PCR-positive samples) were 58 to 93%.
223 Among children positive for the P falciparum housekeeping gene (PF08_0085; ubiquitin-conjugating enzy
224 ominant force driving the evolution of these housekeeping genes, positive selection also appeared to
225 as developed based on the sequences of eight housekeeping genes (ppa, pgm, gyrB, gmk, glyA, atpA, arc
226 ase/autocrine motility factor (PGI/AMF) is a housekeeping gene product present in all cells, is an es
227 ells was initiated by down-regulation of the housekeeping gene product/cytokine PGI/AMF, and the resu
228 ase/autocrine motility factor (PGI/AMF) is a housekeeping gene product/cytokine that catalyzes a step
229 II plays a role in incrementally increasing housekeeping genes, proportionate to the increase in hea
230 expression of Cdrap/Mia, located between two housekeeping genes, provides a distinctive model for res
231 T produces nucleotide sequence data of seven housekeeping genes providing results that are useful for
232 y after photobleaching implied modulation of housekeeping-gene pulse strength occurs at the level of
233 ding a cell wall associated antigen) and one housekeeping gene (pyrC) of 22 E. faecalis isolates chos
234 alyzed nucleotide sequences from portions of housekeeping gene recA (501 bp) and sapD (450 bp), a par
235 intersubspecies lateral gene transfer of the housekeeping gene recA, which has not previously been re
238 scription factors, effectors, and supportive housekeeping genes required for establishing and propaga
239 cular typing based on the allelic profile of housekeeping genes resolved the isolates better than eit
240 nd inlA as well as prs and the hypervariable housekeeping genes ribC and purM showed evidence of hori
242 SWR-C required for expressing the essential housekeeping gene RPS5; and (3) key genes for cell cycle
243 In this study, expression profiles of 16 housekeeping genes selected from C. maculata were cloned
245 phylogenetic analyses of vacA sequences and housekeeping gene sequences indicate that vacA does not
247 n proposed that to optimize gene regulation, housekeeping genes should concentrate on transcriptional
249 studies that evaluated effects on nontarget housekeeping genes, silencing of a nonhousekeeping contr
250 ated 17 ribotypes, and DNA sequencing of the housekeeping gene sodA and the putative virulence gene h
253 correct for sample variability, some common housekeeping genes such as glyceraldehyde-3-phosphate de
254 rase III is highly conserved and transcribes housekeeping genes such as ribosomal 5S rRNA, tRNA and o
255 f bacterial communities by the sequencing of housekeeping genes such as that encoding the small subun
256 ic proteins, but also repress a small set of housekeeping genes - such as those encoding lactate dehy
257 s, especially to conserved regions of common housekeeping genes, such as actin, alpha/beta-tubulin, a
258 biotic-producing functions and depleted from housekeeping genes, suggesting that they have a role in
259 red as selfish genes, outnumber essential or housekeeping genes suggests that they offer selective ad
260 ys are spatially proximal to one another and housekeeping-genes tend to be proximal to several other
262 tative transporters (total 113 kb) and in 39 housekeeping genes that acted as negative controls.
263 +)CD8(+) stage involved a global shutdown of housekeeping genes that is rare among cells of the immun
265 by a process that may be common among other housekeeping genes that reside in large regulatory domai
266 PDH1 is a highly conserved, widely expressed housekeeping gene, the product of which catalyzes the ra
267 On the basis of sequencing analysis with 13 housekeeping genes, the O121:H19 clone did not fall into
269 previously established MLST method based on housekeeping genes to a well-characterized collection of
270 is brings about global repression and allows housekeeping genes to be expressed in all cells of the b
271 osomal retrogenes that evolved from X-linked housekeeping genes to compensate for silencing of the X
272 ng (MLST) analyzes the internal fragments of housekeeping genes to establish genetic relatedness betw
273 hout prior knowledge of or assumptions about housekeeping genes to normalize microarrays that are qui
274 typing utilizing eight chromosomally located housekeeping genes to obtain information about species a
275 the levels of nucleotide divergence in five housekeeping genes to the levels of divergence in their
276 neous hybridization with test and reference (housekeeping) genes to calculate an expression ratio bas
277 MLST) scheme, comprised of seven single-copy housekeeping genes, to genetically characterize Trichomo
278 ched for the insulator binding protein CTCF, housekeeping genes, transfer RNAs and short interspersed
279 for this method, we sequenced regions of six housekeeping genes (trpE, adk, efp, mutY, fumC, and ppa)
280 g improved reference genes over the cohort ('housekeeping genes') typically used for normalisation in
281 t comprised an intergenic region between two housekeeping genes, uncC (proton-translocating ATPase) a
284 which amplify short (<140-bp) regions of the housekeeping genes used by conventional MLST strategies.
285 After in silico analysis, a final set of 7 housekeeping genes was selected (dnaA, metS, recA, tufA,
286 previously published sequence properties of housekeeping genes, was used to develop a method of pred
289 bolic functions, while mRNA levels for these housekeeping genes were low in cells at the bottom of th
291 says were used to detect fungal DNA, and two housekeeping genes were used to assess the presence of a
292 ion partners of functional fusions are often housekeeping genes, whereas the 3' fusion partners are e
293 al intron that has been found to reside in a housekeeping gene which, in this case, encodes a heat-sh
296 elements are more highly concentrated around housekeeping genes while various longer (>400-bp) repeti
298 ding P. penetrans) using concatenation of 40 housekeeping genes, with and without insertions/deletion
300 lity to find tissue- and cell line-optimised housekeeping genes without any prior bias, that again in