ライフサイエンスコーパス: human milk

1 nd iodine) and establish their speciation in human milk.

2 rmine the effect of pH on the proteolysis of human milk.

3 ein, daidzein, caffeic acid, gallic acid) in human milk.

4 Fatty acids are a vital component of human milk.

5 abor intensive and requires large volumes of human milk.

6 ere is a need to quantify arsenic species in human milk.

7 ld standard for measuring the fat content of human milk.

8 ing an additional 80 HMOs from reanalysis of human milk.

9 able in secretions such as saliva, tears and human milk.

10 low birth weight infants discharged home on human milk.

11 y 6% of infants were discharged on exclusive human milk.

12 Most importantly, this activity is unique to human milk.

13 l roles that sIgA and its components play in human milk.

14 uisition and that this activity is unique to human milk.

15 undant and structurally diverse component in human milk.

16 ULITE and SimulTRAC-SNB) for B12 analysis in human milk.

17 asteurisation decreased the pre-lipolysis of human milk.

18 l parameters and the antioxidant activity of human milk.

19 des are the third most abundant component in human milk.

20 the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any hu

21 the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any hu

22 the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any hu

23 the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any hu

24 d the top contributors were formula (71.7%), human milk (22.9%), and commercial baby foods (2.2%).

25 soups (6.1%), pasta mixed dishes (4.0%), and human milk (3.9%).

26 mg GAE/L), sheep (167.6+/-58.77mg GAE/L) and human milk (82.45+/-12.3mg GAE/L).

27 ed evidence suggests that, among infants fed human milk, a shorter versus longer duration of human mi

28 At both 1 and 6 mo, human milk abundance of 1,5-anhydroglucitol, which has n

29 omes from foods other than infant formula or human milk after the age of 6 mo.

30 addressing DHA intakes by lactating women or human milk amounts of DHA at levels above those typical

31 er feeding human milk versus 1) ever feeding human milk and 2) feeding human milk for durations >=6 m

32 tions between 1) never versus ever being fed human milk and atopic dermatitis in childhood or 2) the

33 FAs) and thus higher than typically found in human milk and current infant formula products, without

34 ion and lactation stage may be exploited for human milk and dairy product consumption.

35 method for the determination of parabens in human milk and food with relative recoveries in the rang

36 Evidence examining never versus ever feeding human milk and IBD was inconclusive, and limited, but co

37 cated that differences in the composition of human milk and infant formula yield benefits in cognitiv

38 We measured micronutrient concentrations in human milk and investigated their association with mater

39 nd galacto-N-biose (Gal-beta1,3-GalNAc) from human milk and mucin glycans.

40 matrix interferences by haptocorrin (HC) in human milk and serum show that past analyses of vitamin

41 ublished data on whether it is detectable in human milk and therefore consumed by breastfed infants.

42 ficantly more bioavailable GABA than cow and human milks and are able to activate GABArho receptors.

43 low birth weight infants discharged on "any human milk") and the independent variables (nurse work e

44 s of milk (raw and UHT cows' milk as well as human milk) and infant formulations.

45 e identification of 25 oligosaccharides from human milk, and heatmap analysis revealed the variabilit

46 Human milk, and particularly human colostrum, is the gol

47 Additionally, egg yolks and human milk appear to be bioavailable sources.

48 eir elimination and potential excretion into human milk are not yet fully understood.

49 oclast formation, the expression of TRAIL in human milk as a function of vitamin D status in mothers

50 among children and adolescents who were fed human milk as infants, shorter versus longer durations o

51 f diverse unconjugated glycans that exist in human milk as one of the major components.

52 The WHO refers to human milk as the nutritional gold standard for term inf

53 ified volatile garlic-derived metabolites in human milk as well as in human urine, namely allyl methy

54 murine exudates, regenerating planaria, and human milk as well as macrophages that stimulate tissue

55 o was marginally associated with the rate of human milk at discharge (p=.056).

56 ion and immunological protection provided in human milk at discharge is an issue of health care quali

57 The amount of variability in human milk attributable to diet remains mostly unknown.

58 on the nucleotide contents in samples from a human milk bank.

59 c digestion of lipids and some proteins from human milk but did affect lactoferrin and alpha-lactalbu

60 Human milk but not bovine milk or formula inhibited supe

61 nfants, and 5) feeding a higher intensity of human milk by bottle versus breast with food allergies,

62 l of GML and other lipophilic molecules from human milk by ethanol extraction resulted in a loss of a

63 of arsenic species at low concentrations in human milk by HPLC/ICPMS.

64 BCDs), and tetrabromobisphenol-A (TBBP-A) in human milk collected in 2010-2011 from 10 first-time mot

65 GML may contribute beneficially to human milk compared to bovine milk or infant formula.

66 Very preterm infants receiving human milk compared with infant formula diets have a slo

67 head growth between very preterm infants fed human milk compared with infant formula; and 2) to descr

68 to date examining the metabolic profiles in human milk comparing NW and OB women.

69 owever, whether or not maternal variation in human milk components, such as human milk oligosaccharid

70 ve data from mother-child dyads that capture human milk composition (HMC) and associated health outco

71 r pasteurization has been reported to modify human milk composition and structure by inactivating bil

72 Human milk composition is altered by maternal obesity.

73 seases of the NIH sponsored the "Workshop on Human Milk Composition-Biological, Environmental, Nutrit

74 may persist during lactation and compromise human milk composition.

75 dicate that maternal weight status modulates human milk composition; however, results are conflicting

76 ns reported as mean percentage difference in human milk concentration for each unit higher maternal b

77 Human milk contained approximately 3000 ug/ml of GML, co

78 Human milk contains an abundance of biologically active

79 ntrations of persistent organic chemicals in human milk decrease over the course of lactation.

80 Human milk delivers an array of bioactive components tha

81 r pasteurization (62.5 degrees C, 30 min) of human milk denatures beneficial proteins.

82 is low among VLBW infants fed an exclusively human milk diet including DM-derived fortifier.

83 rth-weight (VLBW) infants fed an exclusively human milk diet of primarily MOM or DM.

84 documented, but the extent to which current human milk diets adequately support growth is uncertain.

85 rom the fetal reference for infants fed both human milk diets compared with formula only (weight z-sc

86 d a close evolutionary relationship with the human milk disaccharide lacto-N-biose-binding protein fr

87 n changed the original volatile compounds of human milk, even more than HoP.

88 l-in-water IF emulsion was formulated with a human milk fat analogue enriched with docosahexaenoic ac

89 derived from fat, we estimated from the TFA human milk fat data that TFA intake of Canadian breastfe

90 tween the percentage of TFAs in the diet and human milk fat established by Craig-Schmidt et al, and a

91 Human milk fat substitute (HMFS) is a class of structure

92 Like human milk fat, HMFS is characterized by enrichment of p

93 is no appropriate biological alternative to human milk fat.

94 s level of C16:0 enrichment is comparable to human milk fat.

95 the "normal" variation in the composition of human milk fatty acids and the contributing dietary, gen

96 Human milk fatty acids are among the nutrients that show

97 tudy were to characterize the composition of human milk fatty acids in a large Canadian birth cohort

98 om effects on neurodevelopment solely due to human milk fatty acids is complex, particularly when neu

99 gy density, will aid in understanding of the human milk fatty acids that best support neurological de

100 g, and 4) lower versus higher intensities of human milk fed to mixed-fed infants with intermediate an

101 nt and no articles examined the intensity of human milk fed to mixed-fed infants.

102 usive human milk feeding or the intensity of human milk fed to mixed-fed infants.

103 ral protein supplementation in predominantly human milk-fed preterm infants.

104 titis in childhood or 2) the duration of any human milk feeding and allergic rhinitis and atopic derm

105 ssociation between the duration of exclusive human milk feeding and blood pressure or metabolic syndr

106 s no association between the duration of any human milk feeding and childhood blood pressure.

107 s between the durations of any and exclusive human milk feeding and intermediate diabetes outcomes in

108 provide an overview on the use of exclusive human milk feeding and the utility of this approach in p

109 ants, shorter versus longer durations of any human milk feeding are associated with higher risk of as

110 milk, shorter versus longer durations of any human milk feeding are associated with higher risk of IB

111 e evidence) and exclusive (limited evidence) human milk feeding are associated with higher type 1 dia

112 ests that the durations of any and exclusive human milk feeding are not associated with intermediate

113 Human milk feeding is an important recommendation for pr

114 an milk, a shorter versus longer duration of human milk feeding is associated with a slightly higher

115 Human milk feeding is associated with lower rates of nec

116 of the included articles examined exclusive human milk feeding or the intensity of human milk fed to

117 shorter versus longer durations of exclusive human milk feeding prior to infant formula introduction,

118 evidence examining the duration of exclusive human milk feeding was scant and no articles examined th

119 ip of shorter versus longer durations of any human milk feeding with celiac disease.

120 k, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations o

121 k, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations o

122 k, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations o

123 k, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations o

124 shorter versus longer durations of exclusive human milk feeding, and 4) feeding a lower versus higher

125 shorter versus longer durations of exclusive human milk feeding, and 4) feeding a lower versus higher

126 shorter versus longer durations of exclusive human milk feeding, and 4) lower versus higher intensiti

127 versus longer durations of any and exclusive human milk feeding, and feeding a lower versus a higher

128 nt is assessed after the period of exclusive human milk feeding.

129 us 1) ever feeding human milk and 2) feeding human milk for durations >=6 mo are associated with a sl

130 paring never feeding human milk with feeding human milk for durations <6 mo is mixed.

131 has implications for the timing of sampling human milk for exposure assessment purposes.

132 The benefits of human milk for hospitalized preterm infants are well doc

133 case-control evidence suggests that feeding human milk for short durations or not at all associates

134 Moderate evidence suggests that feeding human milk for short durations or not at all is associat

135 Feeding human milk for short durations or not at all may be asso

136 mothers to establish and sustain a supply of human milk for their infants.

137 has little or no effect on many nutrients in human milk; for others, human milk may not be designed a

138 n/100 mL of breast milk through a commercial human milk fortifier; n = 30) or a higher-protein group

139 he composition and structures of TAGs in the human milk from mothers with different food choices and

140 HA should equal at least the mean content in human milk globally (0.3% of FAs) but preferably reach 0

141 hese same HMOs established using the shotgun human milk glycan microarray (HM-SGM-v2) showed fair-to-

142 the structures of soluble glycans within the human milk glycome by matching predicted structures base

143 nt of cultured colonic epithelial cells with human milk HA enhances resistance to infection by the en

144 Human milk harbors its own microbiota, but whether the m

145 Human milk has antimicrobial compounds and immunomodulat

146 Lipid droplets in human milk have a mode diameter of ~4 mum and are surrou

147 MC; 3) identify methodological challenges in human milk (HM) collection, storage, and analysis; and 4

148 Human milk (HM) could be considered as a protective fact

149 Human milk (HM) exosomes are highly enriched in microRNA

150 Preterm infants fed fortified human milk (HM) grow more slowly than those fed preterm

151 (HTST, 72 degrees C, 15 s) pasteurization of human milk (HM) has been proposed as an alternative to t

152 Accumulating evidence suggests that human milk (HM) may attenuate the transfer of obesity fr

153 Most American mothers who feed human milk (HM) now use pumps to produce some of the HM

154 Human milk (HM) transforming growth factor beta (TGF-bet

155 ge: 0.1-17.2%) found previously for Canadian human milk in 1992.

156 Human milk in OW mothers was higher in fat and protein a

157 Larger effect sizes were seen with human milk insulin and leptin (0.24 z-score units and 0.

158 Human milk is a complex fluid comprised of myriad substa

159 Human milk is a dynamic protein-protease system that del

160 Human milk is a potential source of lead exposure.

161 ce suggests that never versus ever being fed human milk is associated with higher blood pressure with

162 vidence suggests never versus ever being fed human milk is associated with higher risk of celiac dise

163 suggests that 1) never versus ever being fed human milk is associated with higher risk of childhood a

164 te evidence suggests that feeding less or no human milk is associated with higher risk of type 1 diab

165 A large proportion of human milk is composed of human milk oligosaccharides (H

166 me evidence suggests that feeding less or no human milk is not associated with childhood hypertension

167 ination of free nucleotide monophosphates in human milk is proposed.

168 articular, the composition of fatty acids in human milk is quite variable.

169 Human milk is recommended as the optimal nutrient source

170 Human milk is the optimal nutrition source for infants,

171 Human milk is typically low in vitamin D activity (VDA).

172 on impacted the microstructure of undigested human milk, its gastrointestinal disintegration and tend

173 Human milk leptin, insulin, and CRP concentrations were

174 ence suggests that never versus ever feeding human milk (limited evidence) and shorter versus longer

175 ore closely the structure and composition of human milk lipid droplets.

176 lation between maternal body composition and human milk macronutrients and bioactive components and a

177 In efforts to simulate human milk, many studies have investigated the safety of

178 impact of pasteurization on the digestion of human milk may have nutritional relevance in vivo and po

179 on many nutrients in human milk; for others, human milk may not be designed as a primary nutritional

180 subsp. infantis, a subspecies specialized in human milk metabolism, whereas Russian infants commonly

181 e relationships between maternal obesity and human milk metabolites, infant body composition, and pos

182 aternal adiposity-related differences in the human milk metabolome and to identify metabolites associ

183 al obesity is associated with changes in the human milk metabolome.

184 Human milk metabolomics may be useful in predicting infa

185 esults identify features and determinants of human milk microbiota composition, with potential implic

186 Fewer infants (42%) received human milk mixed with fortifier or formula.

187 Aware of the important benefits of human milk, most U.S. women initiate breastfeeding but d

188 In human milk, NAD levels were significantly affected by th

189 rmulas should be based on the composition of human milk needs revision.

190 validated and applied to analyze HMOs in the human milk obtained from 10 women.

191 a-3) fatty acids from the maternal diet into human milk occurs with little interconversion of 18:2n-6

192 ison of the three methods was conducted with human milk of varying fat content.

193 Lacto-N-tetraose, another common human milk oligosaccharide, was also obtained en route t

194 his knowledge toward the synthesis of -amino human milk oligosaccharides (betaA-HMOs).

195 Human milk oligosaccharides (HMO) are a diverse range of

196 Human milk oligosaccharides (HMO) are favorable macromol

197 These antigens are also found on human milk oligosaccharides (HMO), an abundant and struc

198 estine has been linked to the utilization of human milk oligosaccharides (HMO).

199 , probably due to its large concentration of human milk oligosaccharides (HMO).

200 Human milk oligosaccharides (HMOs) and bioactive breast

201 The prebiotic nature of human milk oligosaccharides (HMOs) and increasing eviden

202 We aimed to explore the association between human milk oligosaccharides (HMOs) and late-onset sepsis

203 of rapidly identifying interactions between human milk oligosaccharides (HMOs) and their protein rec

204 Human milk oligosaccharides (HMOs) are a family of diver

205 Human milk oligosaccharides (HMOs) are free glycans natu

206 ecently growing interest towards synthesized human milk oligosaccharides (HMOs) as baby formula addit

207 obtain a treated milk with 7.0 g/L GOS - the human milk oligosaccharides (HMOs) concentration is betw

208 ed whether differences in the composition of human milk oligosaccharides (HMOs) correlate with infant

209 reported tandem mass spectral library of 74 human milk oligosaccharides (HMOs) derived from results

210 The affinities of thirty-two free human milk oligosaccharides (HMOs) for four human galect

211 Analysis of human milk oligosaccharides (HMOs) from 6-month-postpart

212 Human milk oligosaccharides (HMOs) function as prebiotic

213 Human milk oligosaccharides (HMOs) have important nutrit

214 olute quantitation method for measuring free human milk oligosaccharides (HMOs) in milk samples was d

215 Studies have detected the presence of human milk oligosaccharides (HMOs) in urine of breast-fe

216 Human milk oligosaccharides (HMOs) play an important rol

217 Human milk oligosaccharides (HMOs) promote the developme

218 Human milk oligosaccharides (HMOs) shape gut microbiota

219 Human milk oligosaccharides (HMOs) were recently found i

220 erize interactions among the gut microbiota, human milk oligosaccharides (HMOs), and osteoclast and o

221 variation in human milk components, such as human milk oligosaccharides (HMOs), is associated with p

222 arge proportion of human milk is composed of human milk oligosaccharides (HMOs), which are resistant

223 collection of 60 asymmetric, multiantennary human milk oligosaccharides (HMOs), which were used to d

224 the ability of bifidobacteria to metabolize Human Milk Oligosaccharides (HMOs).

225 roup of complex carbohydrates referred to as human milk oligosaccharides (HMOs).

226 Thus, human milk oligosaccharides may have therapeutic potenti

227 of protein in infant formula and the lack of human milk oligosaccharides promote a shift toward amino

228 luding poly-N-acetyllactosamine derivatives, human milk oligosaccharides, gangliosides and N-glycans.

229 se (2'-FL), a major component of fucosylated human milk oligosaccharides, is beneficial to human heal

230 s were nucleotide derivatives, and 3/10 were human milk oligosaccharides.

231 e molecular sizes and prebiotic functions of human milk oligosaccharides.

232 ibrational spectra of CID fragments from two human milk oligosaccharides.

233 Human-milk oligosaccharides can serve as prebiotics beca

234 ated the impact of pasteurization of preterm human milk on its gastrointestinal kinetics of lipolysis

235 rized diet at NICU discharge/transfer as: 1) human milk only (no formula or fortifier); 2) human milk

236 Diet at discharge/transfer was human milk only for 18,274 (6.6%), mixed for 121,621 (44

237 differences by diet in head z-score change (human milk only, -0.52; mixed, -0.49; formula only, -0.4

238 only (weight z-score change for infants fed human milk only, -0.88; mixed, -0.82; formula only -0.80

239 e and during pregnancy, during the period of human milk or infant formula feeding, and through introd

240 tary feeding is the process that starts when human milk or infant formula is complemented by other fo

241 Complementary feeding (CF) starts when human milk or infant formula is complemented by other fo

242 Introduction of weaning food with either human milk or infant formula reduces the distinct charac

243 is available on B vitamin concentrations in human milk or on how they are affected by maternal B vit

244 milk, and a supplement of pasteurized donor human milk or preterm formula is required.

245 ase in the fraction of infants discharged on human milk (p<0.001).

246 ase in the fraction of infants discharged on human milk (p<0.05).

247 crease in the fraction infants discharged on human milk (p<0.05).

248 Donor human milk, pasteurised for safety reasons, is the first

249 We sought to determine the impact of human milk pasteurization on gastric digestion (particul

250 Pasteurized donor human milk (PDHM) for preterm infant nutrition is fortif

251 ap mass spectrometry, profiles of endogenous human milk peptides before and after incubation at vario

252 Although the release of human milk peptides has been studied during in vivo or i

253 ipolysis extent was 13% lower in pasteurised human milk (PHM) than in raw human milk (RHM).

254 ion of raw human milk (RHM) with pasteurized human milk (PHM).

255 during lactation, independent of changes in human milk production, and few were associated with mate

256 ndividual and interindividual variability of human milk protein and energy content potentially contri

257 n the neonate gut and abundant in bovine and human milk provides a basis for age-restricted tropism a

258 Human milk provides essential nutrients for infant nutri

259 rition can lead to substantial variations in human milk quality.

260 up in comparing the gastric digestion of raw human milk (RHM) with pasteurized human milk (PHM).

261 in pasteurised human milk (PHM) than in raw human milk (RHM).

262 For method validation, a human milk sample was spiked with defined amounts of dim

263 ow concentration HMOs were determined from a human milk sample.

264 ammeline, and ammelide were analyzed in 100 human milk samples collected from the United States duri

265 Human milk samples from 802 mothers were obtained from a

266 We collected human milk samples from healthy and SAM-suffering mother

267 Analysis of Finnish and Chinese pooled human milk samples revealed hundreds of regioisomeric TA

268 The quantitation method was applied to 20 human milk samples to determine the variations in HMO co

269 Human milk samples were collected at 0.5 mo (n = 159), 2

270 Human milk samples were obtained from a longitudinal stu

271 as further tested by analyzing two Norwegian human milk samples where arsenobetaine, dimethylarsinate

272 optimised method, applied to the analysis of human milk samples, included their dilution (1:5) with w

273 presence of calcium, iron, and zinc bound to human milk secretory IgA (sIgA) was investigated.

274 uantified these metabolites in a total of 18 human milk sets, whereby each set comprised of one sampl

275 e relationships of never versus ever feeding human milk, shorter versus longer durations of any and e

276 ol evidence suggests that, among infants fed human milk, shorter versus longer durations of any human

277 he nondigestible oligosaccharides present in human milk show a clear bifidogenic effect on the gut mi

278 (European Childhood Obesity Trial, Norwegian Human Milk Study, and Prevention of Coeliac Disease) tha

279 ghlight the importance of structure specific human milk substitutes and the careful selection of the

280 targeted preventive measures in addition to human milk, such as prebiotics and probiotics, to the ma

281 (HMOs) are free glycans naturally present in human milk that act as prebiotics, prevent pathogen bind

282 preserved the original volatile compounds of human milk, this novel process may be an alternative to

283 The critical importance of human milk to infants and even human civilization has be

284 ) feeding a lower versus higher intensity of human milk to mixed-fed infants with acute childhood leu

285 feeding a lower versus a higher intensity of human milk to mixed-fed infants with diagnosed celiac di

286 ) feeding a lower versus higher intensity of human milk to mixed-fed infants with type 1 and type 2 d

287 ) feeding a lower versus higher intensity of human milk to mixed-fed infants, and 5) feeding a higher

288 (S-BMO) with structures similar to those in human milk to this diet increased femoral trabecular bon

289 rization on the gastrointestinal kinetics of human milk, using a dynamic in vitro system in a preterm

290 Limited evidence suggests that never feeding human milk versus 1) ever feeding human milk and 2) feed

291 e investigated glycerol monolaurate (GML) in human milk versus bovine milk and infant formula for ant

292 and TNF-alpha), and antioxidant activity of human milk was analyzed after the application of differe

293 A pool of preterm human milk was digested as raw or after Holder pasteuriz

294 essure treatments on the volatile profile of human milk was less intense than that caused by HoP.

295 erichia coli), except Enterococcus faecalis, human milk was more antimicrobial than bovine milk and f

296 Human milk was the richest source of nicotinamide mononu

297 Raw (RHM) or pasteurized (PHM) human milk were digested in triplicates using an in vitr

298 Supplementing human milk with DHA at a dose of approximately 1% of tot

299 ia, whereas evidence comparing never feeding human milk with feeding human milk for durations <6 mo i

300 uman milk only (no formula or fortifier); 2) human milk with formula or fortifier (mixed); or 3) infa