ライフサイエンスコーパス: hydrolysis-resistant

1 lly modified oligonucleotides to introduce a hydrolysis-resistant 3'-S-phosphorothiolate linkage at t

2 trations of these four agonists and with the hydrolysis-resistant adenine nucleoside triphosphate ade

3 ary leiomyoma cultures with adenosine or its hydrolysis-resistant analog 2-chloro-adenosine (2-CL-AD)

4 Also, the hydrolysis-resistant analogue, guanosine 5'-O-(3-thiotri

5 The hydrolysis-resistant aryl silicon fragment is promising

6 ted by coincubation of the receptor with the hydrolysis-resistant ATP analog AMP-PNP.

7 sicles with AMP imidodiphosphate (AMPPNP), a hydrolysis-resistant ATP analog, prior to treatment with

8 ncubation of the EGF receptor with AMPPNP, a hydrolysis-resistant ATP analog.

9 than adenylyl imidodiphosphate (AMP-PNP), a hydrolysis-resistant ATP analog; however, this study mai

10 Addition of the hydrolysis-resistant ATP analogue, adenosine 5'-O-(3-thi

11 Phosphorylation of the channel with hydrolysis-resistant ATPgammaS prevented the suppressant

12 s are more potent than the cAMP analogs, and hydrolysis-resistant cAMP analogs are not antiproliferat

13 de (SNP), a nitric oxide (NO) donor, and the hydrolysis-resistant cGMP analogue 8-(4-chlorophenylthio

14 Trehalose or its hydrolysis-resistant derivative lactotrehalose exhibited

15 ed apical PepT1 levels and absorption of the hydrolysis-resistant dipeptide L-Phe(PsiS)-L-Ala (1 mM),

16 take of 1.9 microm glycylsarcosine (a model, hydrolysis-resistant dipeptide) in isolated choroid plex

17 ation in response to saturating doses of the hydrolysis-resistant enkephalin [D-Ala2,N-MePhe4,Gly5-ol

18 ding challenge by rationally designing a new hydrolysis-resistant ester-based linker featuring an iso

19 We found, using hydrolysis-resistant GTP analogs and a mutant Ran unable

20 ase activity of T alpha and the binding of a hydrolysis-resistant GTP analogue to T alpha, while P ga

21 Inclusion of the hydrolysis-resistant guanine nucleotide GDP-beta-S in th

22 des to generate conformationally stabilized, hydrolysis-resistant imines, even when the targeted lysi

23 This finding prompted us to synthesize its hydrolysis-resistant methylenebis(phosphonate) and diflu

24 ines or diagnostic tests, we aimed to create hydrolysis-resistant MPM variants that retain their anti

25 By contrast, expression of Arf6 Q67L, a GTP hydrolysis-resistant mutant, induced the formation of PI

26 t intradermal administration of ATPgammaS, a hydrolysis-resistant P2 agonist, results in an enhanced

27 Synthesis of stereospecific hydrolysis resistant phosphorothioate 2AP-labeled DNA al

28 We performed parallel studies using hydrolysis-resistant phosphorothioate oligonucleotides t

29 ose effects are partially rescued by the GTP hydrolysis-resistant RanQ69L mutant.

30 The mono-MAs are more hydrolysis resistant than DMAs.