ライフサイエンスコーパス: hydrolytic

1 trobacter, and T78 played important roles in hydrolytic-acidification and oil-organics degradation.

2 At the optimum hydrolytic-acidogenic condition which was pH of 6.5, tem

3 bally lacking LAL, we detected residual acid hydrolytic activities against TG and RE.

4 acidification, thereby depressing lysosomal hydrolytic activities and turnover of autophagic and end

5 ecognition receptors (PRRs) and whether host hydrolytic activities facilitate decomposition of bacter

6 ssays revealed the existence of non-LAL acid hydrolytic activities for TG and RE.

7 zyme activity similarly reduced triglyceride-hydrolytic activities in wild-type and CGI-58 overexpres

8 this study, we show that the expression and hydrolytic activities of cellular peptidases are increas

9 es, which were used to identify the range of hydrolytic activities of human sirtuins.

10 In this study, we analyzed the hydrolytic activities of members of a xylan degradation

11 ve been identified, which exhibit a range of hydrolytic activities on lignocellulosic substrates.

12 (Glb1), and hexosaminidase B (HexB), possess hydrolytic activities that temporally remodel N-glycan s

13 ceae, Saprospiraceae and Phaeobacter, and PA hydrolytic activities were over 50% higher.

14 which contains homeostatic and antimicrobial hydrolytic activities, termed hydrolases.

15 of cell wall biosynthetic genes, analysis of hydrolytic activities, transmission electron microscopy,

16 acted in two complementary ways on cathepsin hydrolytic activities: directly on cathepsins and indire

17 Recombinant Sph3 displayed hydrolytic activity against both purified and cell wall-

18 In addition, they have high hydrolytic activity against oxyimino-cephalosporins, des

19 of specific structural elements that confer hydrolytic activity against vancomycin-susceptible pepti

20 We observed cell wall hydrolytic activity and ampicillin binding capacity, a c

21 ted in gain of function, with increased cAMP-hydrolytic activity and enhanced cell proliferation.

22 protein in the reaction depends on both its hydrolytic activity and its ability to interact with oth

23 The effect of thermal treatment on the hydrolytic activity and physical stability of fresh and

24 that cell wall properties and changes in the hydrolytic activity are effective in modulating the comp

25 H18 family, which are devoid of the inherent hydrolytic activity but are able to take glycan oxazolin

26 e (also called endoglycosynthase) that lacks hydrolytic activity but possesses transglycosylation act

27 Further, the hydrolytic activity differed greatly between dark muscle

28 We identified three DAD2 variants whose hydrolytic activity had been separated from the receptor

29 hermore, only StDicer-2 possesses robust ATP hydrolytic activity in the presence of double-stranded R

30 e GP12 protein had potent wall teichoic acid hydrolytic activity in vitro and demonstrated approximat

31 alpha/beta-fold hydrolases, it shows typical hydrolytic activity in vivo and in vitro.

32 Mechanistic experiments suggest that the hydrolytic activity is likely derived from the actuation

33 We suggest that in vivo, the Rca hydrolytic activity is tuned by fluctuating [Mg(2+)] in

34 techniques, we confirm and characterize the hydrolytic activity of 18B7 against peptide mimetics and

35 ose and propose a possible mechanism for the hydrolytic activity of ADIPOR2 using computational appro

36 -activity relationship for inhibition of the hydrolytic activity of beta-galactosidase (Aspergillus o

37 These enzymes enhance the hydrolytic activity of cellulases and are essential for

38 g that it exerts an allosteric effect on the hydrolytic activity of eEF3.

39 NAEs and characterized their effects on the hydrolytic activity of FAAH.

40 and capsule shedding depend on the cell wall hydrolytic activity of LytA.

41 line-rich, C-terminal domain of aSyn nor the hydrolytic activity of PREP was required for the interac

42 property of pol V Mut distinct from the ATP hydrolytic activity of RecA when bound to single-strande

43 tdIns4P levels drop precipitously due to the hydrolytic activity of Sac2 and phospholipase C, becomin

44 In the presence of dichlorvos, the hydrolytic activity of the enzyme is inhibited that the

45 This variation affected hydrolytic activity of the enzyme on artificial substrat

46 ether with fructose, because of the inherent hydrolytic activity of the FTFs.

47 ned the impact of these two processes on the hydrolytic activity of the industrially relevant family

48 e P5A ATPase Spf1p and observed that the ATP hydrolytic activity of the protein is stimulated by phos

49 ng on ADP-ribosylated substrates through the hydrolytic activity of their macro domains.

50 To counteract the hydrolytic activity of these enzymes, combinations of a

51 accounted for essentially all of the misTTR hydrolytic activity of unfractionated human serum.

52 They exhibited high hydrolytic activity on kappa-caseins, cleaving kappa-cas

53 at pasting profile consequence of the enzyme hydrolytic activity on the starch chains.

54 Here we install hydrolytic activity predictably into a completely de nov

55 The hydrolytic activity seemed to be bacteria-dependent and

56 The discovery of GXM hydrolytic activity suggests new therapeutic possibiliti

57 zymatic preparation (Depol 670L) with higher hydrolytic activity toward side chains of RG I as compar

58 tion, thus explaining the lack of detectable hydrolytic activity towards its substrate.

59 ll of the four proteases exhibited selective hydrolytic activity towards meat myofibrillar proteins i

60 Interestingly, this non-LAL acid TG hydrolytic activity was elevated in lysosome-enriched fr

61 n greater precision, for mutations can alter hydrolytic activity, and the ability to confer resistanc

62 of endogenous PDE3A by rPKAc increased cAMP-hydrolytic activity, correlated with shift of PDE3A from

63 CCHs share a conserved aromatic cage for the hydrolytic activity.

64 h strong affinity for PLs, and modulates ATP hydrolytic activity.

65 ically important for modulating the enzyme's hydrolytic activity.

66 nts led to competitive product inhibition of hydrolytic activity.

67 but displayed ca.100-fold difference in LBS hydrolytic activity.

68 ic processing of PLD3 is dispensable for its hydrolytic activity.

69 s act as polyester synthases with negligible hydrolytic activity.

70 protease and the peptide is sensitive to its hydrolytic activity.

71 that selectively disrupts NAT, but not NAE, hydrolytic activity.

72 Hydrolytic and chlorination reactions were demonstrated

73 Microbial communities, including hydrolytic and fermentative bacteria, syntrophic bacteri

74 ps do not exert feedback control on upstream hydrolytic and fermentative processes, as previously sus

75 Selective hydrolytic and hydrogenolytic removal of the aryl maskin

76 nstrate the thermodynamic feasibility of the hydrolytic and nonhydrolytic reaction mechanisms.

77 that C. japonicus utilizes a combination of hydrolytic and oxidative cleavage mechanisms to degrade

78 Manganese oxide was effective at both hydrolytic and oxidative cleavage.

79 B1) and show that this compound perturbs the hydrolytic and oxidative metabolism of endocannabinoids

80 The results show that a diverse set of hydrolytic and redox CAZymes secreted by the morel mycel

81 Both hydrolytic and signaling functions require precise regul

82 In general, hydrolytic and sonochemical Pu colloids can be described

83 a culture-dependent strategy, combined with hydrolytic assays, and high-throughput sequencing using

84 The hydrolytic bacteriophage described in this paper catalyz

85 The aim of this study was to monitor olive hydrolytic (beta-glucosidase) and oxidative (peroxydase,

86 The demonstrated hydrolytic capacities are likely of ecological relevance

87 4E/E1244Q mutant suggests that a transfer of hydrolytic capacity from the canonical to the noncanonic

88 The hydrolytic capacity of BglA was evaluated by measuring t

89 Because Glu-109 is distant from the nuclease hydrolytic center, we have compared the activity of unta

90 ses the reactivity of the silyl ether toward hydrolytic cleavage but also stabilizes the phenolate in

91 modifications were also shown to be prone to hydrolytic cleavage by SIRT1-3 and SIRT6, supporting rec

92 dimeric Pd complexes that mediate the facile hydrolytic cleavage of both CS2 carbon-sulfur bonds at 2

93 protein display by reducing the unproductive hydrolytic cleavage of enzyme-protein covalent intermedi

94 dogenesis in Alzheimer's disease, catalyzing hydrolytic cleavage of substrate in a pH-sensitive manne

95 The hydrolytic cleavage of TGs generates free fatty acids (F

96 by adenine DNA glycosylase, which catalyzes hydrolytic cleavage of the aberrant A nucleobase from th

97 Fe(3+) ion in the active site catalyzes the hydrolytic cleavage of the amide bond in DMF.

98 LTs catalyze the non-hydrolytic cleavage of the bacterial peptidoglycan cell-

99 ation of a catalytic bimetallic site for the hydrolytic cleavage of the RNA model substrate HPNP, who

100 ion suggests that the reaction starts with a hydrolytic cleavage of the triazole ring followed by oxi

101 hose that release acidic moieties only after hydrolytic cleavage, the rate of which could be potentia

102 istinguish between products of oxidative and hydrolytic cleavage, we combined results from the SEQUES

103 -P bond that defines these compounds resists hydrolytic cleavage, while the phosphonyl group is a ver

104 ound phenols from millet in acidic and basic hydrolytic conditions were compared for the first time.

105 e resulting copolymers readily degrade under hydrolytic conditions, in addition to cysteine-mediated

106 mally and under both strong acidic and basic hydrolytic conditions.

107 ne produced 2-amino-S-adenosylmethionine for hydrolytic conversion to 2AMTA.

108 oenzyme was not the limiting step of the ATP hydrolytic cycle.

109 igh frequency in genomic DNA via spontaneous hydrolytic, damage-induced or enzyme-mediated base relea

110 NAAA catalyzes the hydrolytic deactivation of palmitoylethanolamide (PEA),

111 cylglycerol lipase (MGL), a key actor in the hydrolytic deactivation of the endocannabinoid 2-arachid

112 The hydrolytic deamination of cytosine and 5-methylcytosine

113 By exploiting differential kinetics of hydrolytic deamination reactions of cytosine and its nat

114 Hydrolytic dechlorination of delta-HCH by LinB exhibited

115 CBQ, p-chloranil), accompanied by a two-step hydrolytic dechlorination of highly toxic TCBQ into the

116 ious study in which it was demonstrated that hydrolytic decomposition of meropenem in living Escheric

117 Rapid release of drug occurs upon hydrolytic decomposition of MOF in dissolution media.

118 rted that affords the ability to monitor the hydrolytic decomposition of the carbapenem antibiotic me

119 I(hoz)2 concentration builds up and leads to hydrolytic decomposition to ReO4- and free hoz ligand.

120 Only negligible hydrolytic decomposition was observed in the pH range fr

121 In particular, oxidative and hydrolytic degradation (by routine and non-conventional

122 be that D14 deactivates bioactive SLs by the hydrolytic degradation after signal transmission.

123 This glycopeptide is more resistant to hydrolytic degradation and binds with higher affinity to

124 es the intracellular nucleotide pool through hydrolytic degradation of canonical and noncanonical nuc

125 tably, the prominent role of trypsins in the hydrolytic degradation of major allergens is demonstrate

126 f water and its physical state influence the hydrolytic degradation of PLA films.

127 rs prepared by a step-growth synthesis, that hydrolytic degradation of poly(lactic- co-glycolic acid)

128 The hydrolytic degradation of squaramides and squaramic acid

129 The rate of hydrolytic degradation of the hydrogel depended on the i

130 synergy and orthogonality of photolytic and hydrolytic degradation, we designed concentric cylinder

131 per thousand (aerobic C-Cl bond cleavage via hydrolytic dehalogenation), and -57 +/- 3 per thousand a

132 4 (oxidation), 0.7 +/- 0.1 and 0.9 +/- 0.1 (hydrolytic dehalogenation), and 1.76 +/- 0.05 and 3.5 +/

133 xes are air-stable and promote the catalytic hydrolytic dehydrogenation of ammonia borane.

134 enzymes that catalyze the post-translational hydrolytic deimination of arginine residues.

135 se, thus boosting the activity of well-known hydrolytic depolymerizing enzymes.

136 s study was to determine the composition and hydrolytic deterioration behavior of rice bran fractions

137 tion in Beijing can be explained by enhanced hydrolytic disproportionation of NO2 on aqueous aerosol

138 s: predominantly inward-facing apo P-gp, pre-hydrolytic (E552Q/E1197Q) P-gp bound to Mg(+2)-ATP, and

139 ond formation in the polymerase site and for hydrolytic editing in the exonuclease site.

140 ing domain that would be expected to disrupt hydrolytic editing of mischarged tRNA(Leu) and to result

141 , minimize translational errors by intrinsic hydrolytic editing.

142 Pressurisation (100-300 MPa) enhanced the hydrolytic efficiency of Protamex, Savinase and Corolase

143 1 (BGAL1) of Nicotiana benthamiana promotes hydrolytic elicitor release and acts in immunity against

144 tion in the genome that can be identified by hydrolytic end sequencing, we show that Pol delta replic

145 ct the activity of a diagnostically relevant hydrolytic enzyme and remove the analytically harmful in

146 ative structure and catalytic ability of the hydrolytic enzyme beta-galactosidase, which serves as th

147 ococcus and a dynamic secretion of potential hydrolytic enzyme candidates used by the heterotroph to

148 disease caused by deficient activity of the hydrolytic enzyme galactosylceramidase (GALC).

149 5' processive exoribonuclease, is the major hydrolytic enzyme in Escherichia coli accounting for app

150 croorganisms, which causes the repression of hydrolytic enzyme secretion by industrially relevant fil

151 ABHD12 is a membrane-bound hydrolytic enzyme that acts on the lysophosphatidylserin

152 lysis(5), here we report the generation of a hydrolytic enzyme that uses N(delta)-methylhistidine as

153 assay for the total activity of cellulase, a hydrolytic enzyme widely used in food and textiles indus

154 Overall, this study describes a PG hydrolytic enzyme with a hitherto unknown substrate spec

155 the most efficient known naturally occurring hydrolytic enzyme, acetylcholinesterase, the catalytic a

156 at its product profile differs from those of hydrolytic enzymes acting on the same substrates.

157 Accumulation of starch hydrolytic enzymes along with different types of malto-o

158 Activity of the hydrolytic enzymes alpha-amylase and lipase along with s

159 erization of recalcitrant polysaccharides by hydrolytic enzymes and are found in the majority of cell

160 n is continually remodelled by synthetic and hydrolytic enzymes and by chemical modifications, includ

161 ry revealed significantly elevated lysosomal hydrolytic enzymes and plasma membrane-associated protei

162 conserved and implicated in the secretion of hydrolytic enzymes and toxins for a range of bacteria.

163 The hydrolytic enzymes called beta-lactamases are responsibl

164 d fiber destruction, including the action of hydrolytic enzymes derived from fresh food waste and con

165 l resin can very likely be expanded to other hydrolytic enzymes dissolved in any analyte matrix and e

166 en shown to be potent inhibitors of numerous hydrolytic enzymes due to the open shell of boron, which

167 ogical significance for the complex array of hydrolytic enzymes expressed by plant cell wall-degradin

168 Filamentous fungi are powerful producers of hydrolytic enzymes for the deconstruction of plant cell

169 The high cost of hydrolytic enzymes impedes the commercial production of

170 rbohydrate turnover and exhibit synergy with hydrolytic enzymes in biomass depolymerization.

171 e morphology on the synergy between LPMO and hydrolytic enzymes in cellulose depolymerization.

172 Although the actions of many of the hydrolytic enzymes involved in cellulose hydrolysis are

173 of intramolecular synergy between LPMOs and hydrolytic enzymes reported here opens new avenues towar

174 Here, we identify hydrolytic enzymes secreted by P. destructans, and use a

175 se of the local concentration and cascade of hydrolytic enzymes that can rapidly degrade cells and RN

176 age of septal PG is mediated by PG amidases, hydrolytic enzymes that release peptide side chains from

177 hat Swollenin might act synergistically with hydrolytic enzymes to initiate biomass deconstruction wi

178 smoke compounds precisely regulated ABA and hydrolytic enzymes under all light conditions.

179 thought to rely on the synergistic action of hydrolytic enzymes, but recent work has shown that lytic

180 Used in combination with hydrolytic enzymes, LPMO appears to constitute a signifi

181 osides that are stored separately from their hydrolytic enzymes, myrosinases, in plant tissue.

182 ygen, despite belonging to a large family of hydrolytic enzymes, the HD-phosphohydrolase superfamily.

183 levels of ABA and enhancing the activity of hydrolytic enzymes, which aids in mobilizing stored rese

184 substrate and promote biomass degradation by hydrolytic enzymes.

185 selective radiation of surface proteins and hydrolytic enzymes.

186 te the generality of this system for imaging hydrolytic enzymes.

187 orage was compromised due to the presence of hydrolytic enzymes.

188 of reactive oxygen and nitrogen species and hydrolytic enzymes.

189 as thought to be accomplished by mixtures of hydrolytic enzymes.

190 ganic matter through increased production of hydrolytic enzymes.

191 idoglycan remodeling involving synthetic and hydrolytic enzymes.

192 rmer temperatures, and increased activity of hydrolytic enzymes.

193 splaced by glucose and free to inhibit other hydrolytic enzymes.

194 cing ABA levels and reducing the activity of hydrolytic enzymes.

195 molecules are removed through degradation by hydrolytic enzymes.

196 l modes of coordinated hydrolysis, featuring hydrolytic events in two oppositely positioned ATPases,

197 to the RNB family of enzymes, is a 3' to 5' hydrolytic exoribonuclease able to digest highly structu

198 RNase R is a 3' to 5' hydrolytic exoribonuclease that has the unusual ability

199 gy was then applied to both acidic and basic hydrolytic extractive conditions: the acidic procedure,

200 ith some beta-lactam antibiotics undergo non-hydrolytic fragmentation.

201 the Exo1-E109K mouse in the context of Exo1 hydrolytic function.

202 rity of disposal units to contain PFCAs upon hydrolytic generation from FTPs.

203 ly of the divisome at midcell and to prevent hydrolytic growth of the cell in the absence of a comple

204 ol glycosides in stevia leaves known for its hydrolytic instability responsible for the formation of

205 Although pi-pi stacking between layers, hydrolytic instability, possible restacking prevents the

206 escribed so far have several drawbacks, like hydrolytic instability, slow reaction kinetics or not re

207 Jacobsen's hydrolytic kinetic resolution and Sharpless' asymmetric

208 e Brabander's esterification, and Jacobsen's hydrolytic kinetic resolution as the key steps.

209 harpless asymmetric epoxidation and Jacobsen hydrolytic kinetic resolution, were utilized to achieve

210 Wide substrate scope of RPA1163 in such hydrolytic kinetic resolutions can be expected because t

211 tatistical interactions elucidated different hydrolytic kinetics and developments in higher alcohol a

212 Both the hydrophobicity and hydrolytic lability of these silicates can be (independe

213 prodrug vinyl monomers with self-immolative hydrolytic linkers or cathepsin-cleavable valine-citrull

214 ophan or synthetic tryptophan to correct for hydrolytic losses of tryptophan overestimated the trypto

215 into phagolysosomes, acquiring an acidic and hydrolytic lumen that kills the pathogens.

216 mplex in silico and used it to elucidate the hydrolytic mechanism in a GH45, Cel45A from the fungus H

217 nt suggests that Tyr-166 participates in the hydrolytic mechanism of the enzyme.

218 ence of any reductants, apparently through a hydrolytic mechanism that generates a sulfenic acid/thio

219 However, the hydrolytic mechanisms underlying such a powerful synthet

220 and Pu colloids produced by sonochemical and hydrolytic methods, has been conducted using HRTEM, Pu L

221 Excess misTTR was dissolved by a hydrolytic mIgM.

222 .e. to catalyse the reverse of their natural hydrolytic mode of action, allow the attachment of N-gly

223 iospecificities and can adopt three distinct hydrolytic modes of action: exo, endo-dissociative, and

224 These hydrolytic modes regulate deubiquitylation, initiation o

225 wn that disruptive proteins, such as the non-hydrolytic non-oxidative protein Swollenin, can open up

226 The endoperoxide also undergoes hydrolytic opening followed by further transformations t

227 minant pathway for coping with most forms of hydrolytic, oxidative or alkylative DNA damage.

228 between both NBDs, and they suggest that pre-hydrolytic P-gp occupies an occluded conformation.

229 aglycon and other subsequent products in the hydrolytic pathway can be catalyzed by different enzymes

230 Thus, we conclude that the advantage of the hydrolytic pathway is that it provides a means to overco

231 oxazolines, high energy intermediates on the hydrolytic pathway, as activated donors allows their hig

232 ctose varied depending on the concentration, hydrolytic power of acids and molecular interactions in

233 ble to EDTA (10mM) with irreversible loss of hydrolytic power.

234 A lower rate of the hydrolytic process was observed in BHT samples.

235 bond, and of being reversible due to a fast hydrolytic process.

236 Changes due to hydrolytic processes were also considered.

237 pT1 like transporters/SOPT2 while BCM 5, its hydrolytic product and bradykinin were suggested to be t

238 cells specifically internalized C3(H2O), the hydrolytic product of C3, and not native C3, from the ex

239 C-terminal amino acid residue (>=100:1) and hydrolytic product release.

240 These bound hydrolytic products are likely to be the basis of inhibi

241 These bound hydrolytic products are probably the basis of the inhibi

242 Analysis of the hydrolytic products by liquid chromatography, coupled wi

243 ide variation observed in the profile of GLS hydrolytic products of different extracts obtained from

244 Hydrolytic products of more stable substrates (catechol

245 methylation is due to the action of specific hydrolytic products of THB (most probably by the first a

246 ormone, and then covalently binds one of the hydrolytic products.

247 Expansins are non-hydrolytic proteins present in the cell wall, and their

248 NEXAFS indicated that oxygen state in hydrolytic Pu colloid is influenced by hydrolysed Pu(IV)

249 ed the genotypic diversity of lipase induced hydrolytic rancidity (HR) level in the bran of 134 diver

250 , temperature had little or no effect on the hydrolytic rate in dilute substrate suspensions, whereas

251 lonal IgMs (mIgMs) expressed variable misTTR hydrolytic rates and differing oligoreactivity directed

252 However, ATP hydrolytic rates are stimulated by SSB through its C ter

253 We measured hydrolytic rates of four purified cellulases in small in

254 The suggested pathway of the hydrolytic reaction at the editing site of PheRS is of s

255 res, the present results reveal the complete hydrolytic reaction coordinate for this naturally and in

256 rate N-acyl amino acids and also the reverse hydrolytic reaction.

257 These enzyme-mediated hydrolytic reactions are fundamental for the replication

258 s salt can be manifested in chlorination and hydrolytic reactions occurring during thermal processing

259 The synthesis, structural characterization, hydrolytic reactivity, and in vitro cytotoxicity against

260 layer spacing, reveals a much more extensive hydrolytic rearrangement than previously thought.

261 mbedded in the flagellin polymer and require hydrolytic release before they can activate cell surface

262 These features could facilitate hydrolytic release of the amino acid, especially for 3'

263 ed multicavities are synthesized through the hydrolytic removal of silica cluster templates from orga

264 reduction by Pd-activated hydrogen, and (3) hydrolytic ReVII(hoz)2 decomposition.

265 The major products are consistent with a hydrolytic ring fragmentation pathway as the principal m

266 openylmethyl trichloroacetimidates undergo a hydrolytic ring-opening reaction to form allenylcarbinol

267 as proton conductors, both conductivity and hydrolytic robustness of the materials have needed to be

268 Hydrolytic serum enzymes could play an important role in

269 eu5Ac2en, also known as DANA), a nonspecific hydrolytic sialidase inhibitor.

270 d faster than ProD due to the more number of hydrolytic sites in ProS for both enzymes.

271 The hydrolytic specificity of An-PEP for purified alpha-CN w

272 The hydrolytic specificity of Aspergillus niger prolyl endop

273 We have further examined the hydrolytic specificity of this enzyme and chitinases fro

274 e-linked AIP analogues with greatly enhanced hydrolytic stabilities and solubilities relative to our

275 g/mL), free fraction levels (>20% free), and hydrolytic stability (t1/2 >/= 100 h) were identified.

276 g indices (>93), long shelf life, and superb hydrolytic stability at ambient conditions.

277 pacity) as well as the dramatically improved hydrolytic stability of composite.

278 Overall, our results demonstrate that the hydrolytic stability of functional, natural peptide sequ

279 The hydrolytic stability of SIFSIX-2-Cu-i in comparison to i

280 Differences in the hydrolytic stability of the glycosidic bonds and in the

281 Pertinently, the notable hydrolytic stability positions NbOFFIVE-1-Ni as the new

282 These prodrugs have good hydrolytic stability properties and improved solubility

283 y, chemical functionalities, and appropriate hydrolytic stability to expand their therapeutic applica

284 Further, 1 exhibits exceptional hydrolytic stability with the CO2 adsorption isotherm be

285 ra-low temperatures and displays exceptional hydrolytic stability, as demonstrated by the retention o

286 aterials reported so far, together with good hydrolytic stability, indicates potential for efficient

287 ic and functional bioconjugates with tunable hydrolytic stability.

288 g groups to produce metal-linker joints with hydrolytic stability.

289 dynab, that binds preferentially to the GTP hydrolytic state of dynamin-1.

290 ate, nucleotide trapping in the pre- or post-hydrolytic state was required for a pronounced conformat

291 In the pre-hydrolytic state, both interfaces between ICHs and NBDs

292 ) showed reduced deuterium uptake in the pre-hydrolytic state, consistent with an occluded conformati

293 Proteolytic processing is dispensable for hydrolytic sulfatase activity in vitro.

294 The library is applied to predict the likely hydrolytic transformation products for two lists of chem

295 table EA content was observed following acid hydrolytic treatment of FPW.

296 The results obtained so far suggest that the hydrolytic treatment of this industrial by-product, with

297 ic costs of this proofreading are met by the hydrolytic turnover of a phosphate activating agent and

298 P)-mediated GTP hydrolysis by displacing the hydrolytic water molecule, whereas introduction of a bul

299 ketenimines as electrophiles and subsequent hydrolytic workup resulted in novel enamine derived amid

300 ange of homoallylic primary amines following hydrolytic workup.