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1 ation changes gradually in the cap as GTP is hydrolyzed.
2 s proportional to the number of peptide bond hydrolyzed.
3 gely lost with this RecA variant when ATP is hydrolyzed.
4 imary isonitriles that are otherwise rapidly hydrolyzed.
5 covered as the anhydride and ester bonds are hydrolyzed.
6 eight residues are translocated for each ATP hydrolyzed.
8 ydrolase domain 6 (hABHD6) is an enzyme that hydrolyzes 2-arachidonoylglycerol (2-AG), a potent agoni
9 orylated nucleotides as with RNA, the enzyme hydrolyzes 5'-triphosphorylated nucleotides by extending
10 s also indicated that iPLA2gamma selectively hydrolyzes 9-hydroxy-octadecenoic acid in comparison to
11 function, we tested the ability of MBLAC2 to hydrolyze a variety of small molecules and acylprotein s
12 overlapping substrate specificities and may hydrolyze a wide range of peptidic epitopes; it is there
15 a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organ
17 On the other hand, FAT10 inhibits PDE6 cGMP hydrolyzing activity by noncovalently interacting with t
19 d messenger typically derived from the lipid-hydrolyzing activity of PLDalpha1, is a molecular target
20 / S-adenosylhomocysteine nucleosidase (MTAN) hydrolyzes adenine from its substrates to form S-methyl-
21 injected into mouse visceral adipose tissue hydrolyzed adipose triglyceride and generated excess non
22 d entered adipocytes by multiple mechanisms, hydrolyzing adipose triglyceride and generating excess N
23 ons, and we find strong correlations between hydrolyzed adsorbates and particle-adhesion forces, sugg
26 Currently, bacterial polysaccharidases that hydrolyze agars (beta-agarases and beta-porphyranases) h
27 sequential hydrolysis by pepsin and trypsin hydrolyzed all heavy molecular weight chains of collagen
28 e digestive proteases used were efficient in hydrolyzing almond proteins, regardless of the extractio
29 nd characterize novel microbial enzymes that hydrolyze alpha-GalNAc, we screened small-insert librari
30 icated a chemical reaction between amine and hydrolyzed amide groups of nylon and MAH groups on the M
31 properties of infant formula (IF) containing hydrolyzed and intact (non-hydrolyzed) whey protein in t
32 ally formed 5-alkenyl iminohydantoins may be hydrolyzed and oxidatively deprotected to yield hydantoi
34 horic-molybdic anhydride becomes immediately hydrolyzed and, according to the current data, the relea
35 f cathepsin cannibalism, where one cathepsin hydrolyzes another with substrate present, and misunders
38 mitochondrial form of arginase (ARG2), which hydrolyzes arginine into ornithine and urea, is induced
40 ich induced a reversal of the F1Fo-ATPase to hydrolyze ATP and generated the deleterious voltage.
41 and one or two AAA+ HslU ring hexamers that hydrolyze ATP to power the unfolding of protein substrat
42 The vacuolar-type H(+)-ATPases (V-ATPase) hydrolyze ATP to pump protons across the plasma or intra
44 nction is coupled to its ability to bind and hydrolyze ATP, which is tightly regulated both by co-cha
46 ases family, transports two calcium ions per hydrolyzed ATP molecule via an "alternating-access" mech
49 ncontracting, "relaxed" muscle, myosin still hydrolyzes ATP slowly, contributing to the muscle's over
52 -repressor." In vitro, ParA(R351A) binds and hydrolyzes ATP, and undergoes a specific conformational
56 onor was washed, dried, homogenized and acid hydrolyzed before analysis using liquid chromatography-i
60 ysis of the amino-acid residues flanking the hydrolyzed bonds revealed a set of residue motifs that w
62 ared use of a formula containing extensively hydrolyzed bovine proteins (whey and/or casein) with use
63 green leaf volatile with a grassy aroma when hydrolyzed, but not on the other aroma glucosides, which
64 rm 2-carboxy-l-lyxonolactone; the lactone is hydrolyzed by a member of the amidohydrolase superfamily
68 s from okara (soybean by-product) previously hydrolyzed by Cynara cardunculus enzymes and fermented b
73 phalosporins, including cefepime, are poorly hydrolyzed by specific ESBL enzymes, and certain strains
77 cond step, the trisaccharide is specifically hydrolyzed by trehalase, to obtain blastose in 43.2% mol
79 in solution and binds Mn(2+) to specifically hydrolyze c-di-AMP to AMP via the intermediate 5'-pApA.
82 carbapenemase (KPC) is a widespread SBL that hydrolyzes carbapenems, the most potent beta-lactams; kn
83 est whether administration of an extensively hydrolyzed casein formula (EHCF) containing the probioti
85 higher levels of both fermentable sugars and hydrolyzed cellulose and altered cell wall properties su
88 eriments revealed that this haloarchaeon can hydrolyze chitin outside the cell (to produce the monosa
90 with bacterial species that carry carbapenem-hydrolyzing class D beta-lactamases (OXA-23, OXA-24/40 a
91 orm of butyrylcholinesterase, an enzyme that hydrolyzes cocaine, enables the long-term release of the
93 re design of organophosphate hydrolases that hydrolyze compounds with challenging leaving groups.
94 d to undergo cyclization and was exclusively hydrolyzed, confirming the TE domain as a key catalytic
95 sides, which have more desirable aromas when hydrolyzed, could have an impact on beer aroma profiles.
96 a NlpC/p60-endopeptidase that preferentially hydrolyzes crosslinked Lys-type peptidoglycan fragments.
98 otein domain present in several enzymes that hydrolyze cyclic phosphate bonds on different substrates
100 al condensation (C) domain stereoselectively hydrolyzes d-tryptophanyl-S-phosphopantetheine thioester
101 say for the Zn(II)-dependent, chlorothalonil-hydrolyzing dehalogenase from Pseudomonas sp. CTN-3 (Chd
103 Prototype MacroD-type macrodomains also hydrolyze derivative linkages on the distal ribose ring.
105 find that several hundred ATP molecules are hydrolyzed during refolding of each ribozyme molecule.
107 partially hydrolyzed (PH), four extensively hydrolyzed (EH), and one amino acid formula, using bioch
108 ic index probably by inhibiting carbohydrate hydrolyzing enzyme activity which could be attributed to
109 n posttranscriptional repression of the cAMP-hydrolyzing enzyme phosphodiesterase-3b (Pde3b) by micro
110 protein signaling (RGS1) protein and a lipid-hydrolyzing enzyme, phospholipase Dalpha1 (PLDalpha1), b
111 lacks sequence similarity with other NAD(+) hydrolyzing enzymes and lacks the essential motifs invol
112 thods by lactic acid fermentation, cell wall hydrolyzing enzymes and phytase on the biochemical (prot
114 tributors of the inhibition of carbohydrates hydrolyzing enzymes as well as with the antiproliferativ
115 y of microtubule regulators includes the ATP-hydrolyzing enzymes spastin, katanin, and fidgetin, whic
116 are of grave clinical concern and carbapenem-hydrolyzing enzymes such as KPC (class A) NDM (class B)
119 ing to carbohydrate esterase family 1 (CE1), hydrolyze ester bonds between ferulic acid (FA) and arab
121 evealed that both mammalian Nudt2 and Nudt16 hydrolyze FAD-capped RNAs in vitro with Nudt16 regulatin
126 tty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl 4'-phosphopantet
130 FUC1 (Bd3g25226) and BdXFUC2 (Bd1g28366) can hydrolyze fucose from xyloglucan oligosaccharides but we
133 nd that both AtPTPN and ZmPTPN release Pi by hydrolyzing GDP/GMP/dGMP/IMP/dIMP, and that AtPTPN posit
135 emarkably, the nanohaloarchaeon's ability to hydrolyze glycogen and starch to glucose enabled growth
136 The enzymatic dispersal of biofilms by PNAG-hydrolyzing glycosidase enzymes, such as Dispersin B (Ds
137 s of this machinery and use their ability to hydrolyze GTP and to polymerize into helices and rings t
138 ecifically, how do these regulatory proteins hydrolyze GTP without an obvious general base in the act
139 educe the ability of the small GTPase RAS to hydrolyze GTP, keeping this molecular switch in a consti
140 protofilaments that treadmilled at 23 nm/s, hydrolyzed GTP at 3.6-3.7 GTP min(-1) FtsZ(-1), and had
141 rofibromin protein (encoded by the NF1 gene) hydrolyzes GTP directly in complex with KRAS G13D, and K
143 ations that retain the intrinsic capacity to hydrolyze guanosine triphosphate, suggesting that the me
144 hree endolytic alginate lyases predominantly hydrolyzed guluronic acid-rich alginates, only CaAly1 al
145 ly labeled 15N-casein (33-34 g), in either a hydrolyzed (HC) or intact (C) form, was included as the
148 se (TA) - is a type of tannin acyl-hydrolase hydrolyzing HTs, CT monomer gallates and depsides - has
149 sulfonamide antibiotics (SAs)) in synthetic hydrolyzed human urine and uncovered new effects from ur
151 pathogens and their potential to be rapidly hydrolyzed (i.e., inactivated) by extracellular peptidas
153 mination of the N170A enzyme in complex with hydrolyzed imipenem suggests Asn170 may prevent the inac
155 rom GWA honeydew honey was not significantly hydrolyzed in crude human-stomach and human-small-intest
156 when deciphering the mechanism: while ATP is hydrolyzed in large quantity during the process, how exa
157 table product-reduced CTQ adduct that is not hydrolyzed in the absence of O(2) Asp-678 resides near t
159 a-glucosidase in A. thaliana root ER bodies, hydrolyzes indole glucosinolates (IGs) in addition to th
160 stabilization of the urine, urea is quickly hydrolyzed into ammonia and (bi)carbonate, causing nutri
161 en source in soils provided that they can be hydrolyzed into bioavailable small peptides or amino aci
162 galactosylated by BoGal36A, and subsequently hydrolyzed into mainly mannobiose by the beta-mannanase
163 extracellular fungal protease (Rhizopus sp.) hydrolyzed iron oxide-associated bovine serum albumin (B
164 exonuclease activity on single-stranded DNA, hydrolyzing it at the acidic pH associated with the lyso
165 able to different metal ions and was able to hydrolyze kappa-casein similarly to bovine chymosin.
166 gradually during the simulated digestions to hydrolyze lactose in milk more efficiently than free lac
172 Angiotensin-converting enzyme (ACE) can hydrolyze many peptides and plays a central role in cont
173 ipoprotein lipase (LPL) may more efficiently hydrolyze medium length triacylglycerides (TAGs) than ot
175 h, we took advantage of the binding modes of hydrolyzed metabolites of several thalidomide-derived ef
176 ith Linear Linkage Specificity) specifically hydrolyzes methionine1 (Met1)-linked ubiquitin chains co
177 S is prepared through sponge absorption of a hydrolyzed mixture of siloxanes and in situ gel formatio
178 sis had a unique enzyme that can selectively hydrolyze mogrol glycosides and promote the conversion o
179 enzymatic step in triglyceride degradation, hydrolyzing monoglycerides into glycerol and fatty acids
183 enzymatic activity of TNT and found that TNT hydrolyzes NADP(+) as fast as NAD(+) but does not cleave
186 algae collection, we demonstrate that ZgAgaC hydrolyzes not only agarose but also complex agars from
188 tRNA synthetases (I/L/VRSs), all efficiently hydrolyze Nva-tRNAs even when editing of Nva seems redun
192 be orthogonal, such that each protease only hydrolyzes one unique substrate, however this is impract
194 eate or use malonyl-thioesters spontaneously hydrolyze or decarboxylate reactants on the crystallogra
195 me is a protease, a subclass of enzymes that hydrolyze other proteins, and that protease is in a mult
196 ate), indirectly bioavailable P (phosphatase-hydrolyzed P) and nonbioavailable P (nonhydrolizable P)
197 known as YvcI) efficiently produces pGpp by hydrolyzing (p)ppGpp, thus modulating alarmone compositi
199 Originally recognized for their ability to hydrolyze penicillins, emergent beta-lactamases can now
201 s are genuine Xaa-Pro aminopeptidases, which hydrolyze peptides with proline at the second position (
203 Release factors (RFs) decode the stop codon, hydrolyze peptidyl-tRNA to release the nascent protein,
204 ing, we find that approximately 100 ATPs are hydrolyzed per refolded RNA as a consequence of interact
206 of adenosine 5'-triphosphate (ATP) molecules hydrolyzed per step is demonstrated to be invariant to e
207 M formulas, one nonhydrolyzed, two partially hydrolyzed (PH), four extensively hydrolyzed (EH), and o
208 e chloroplasts and microsomal membranes, and hydrolyzes phosphatidylcholine and galactolipids to prod
215 PLIP1 is a phospholipase A1 In vivo, PLIP1 hydrolyzes polyunsaturated acyl groups from a unique chl
217 activated platelets release ADAMDEC1, which hydrolyzes pro-EGF to soluble HMW-EGF, that HMW-EGF is a
219 n postulated that pyrazinoic acid (POA), the hydrolyzed product of PZA, could inhibit trans-translati
222 e cyclic AMP (adenosine monophosphate; cAMP)-hydrolyzing protein PDE4B (phosphodiesterase 4B) is a ke
226 nd and sodium borate as the salt, the borate hydrolyzes rapidly in response to moisture and produces
227 nder conditions tested, the NF1-LRD fails to hydrolyze Ras-GTP to Ras-GDP, suggesting that its suppre
228 inetically distinct subpopulations: a faster-hydrolyzing "relaxed" population, and a slower-hydrolyzi
230 lational modification, RNase H that actively hydrolyzed RNA, and exenatide that is a commercial thera
231 content (S %) was very low for sulfuric acid hydrolyzed samples, and X-ray results did not show any s
232 izing modified silica sol-gel chemistry, pre-hydrolyzed silica precursor clusters can be uniformly co
234 s released extracellularly within seconds to hydrolyze sphingomyelin preferentially enriched in outer
236 , we demonstrated that this protease rapidly hydrolyzes Staphylococcus aureus protein A, an important
238 that the native CsTA and six recombinant TAs hydrolyze tannin compounds, depsides and phenolic glycos
239 r facilitates the subsequent condensation of hydrolyzed TEOS, which builds up the shell layer of smHS
240 gative bacteria, beta-lactamase enzymes that hydrolyze the amide bond of the four-membered beta-lacta
241 tremes, a major group of enzymes diverged to hydrolyze the backbone of xyloglucan nonspecifically wit
243 ipase (MGL), an enzyme that is also known to hydrolyze the endocannabinoid 2-arachidonoylglycerol in
244 codon, it recruits a release factor (RF) to hydrolyze the ester bond between the peptide chain and t
245 ghly engineered phytases, which sequentially hydrolyze the hexakisphosphate ester of inositol known a
246 olymer backbone intact under conditions that hydrolyze the lactone and allows the ester group to be r
250 pH of the reaction media, it is possible to hydrolyze the oxirane moiety leading to 21 % yield of al
252 was prevented, or when purified proteasomes hydrolyzed the associated ubiquitin conjugates, Usp14 an
256 levels of beta-glucuronidase, an enzyme that hydrolyzes the glycosidic bond of glucuronides to genera
258 essed in bone, teeth, liver, and kidney that hydrolyzes the mineralization inhibitor inorganic pyroph
259 mnogalacturonan lyase, a secondary pectinase hydrolyzing the pectic heteropolymer, rhamnogalacturonan
262 s, as illustrated by the identification of a hydrolyzed thiosuccinimide ring of SigmaMAb ADC mimic fo
263 urine forms with retinaldehyde would readily hydrolyze to release the retinoid and thus may embody a
264 tandem MS experiments revealed that 4-MUG is hydrolyzed to 4-MU in serum, thereby greatly increasing
265 )C]-l-alanine ethyl ester is instantaneously hydrolyzed to [1-(13)C]-l-alanine, and subsequently meta
266 P) to the extracellular medium, which can be hydrolyzed to adenosine by ectonucleotidases such as ect
268 ne to water and cystathionine, which is then hydrolyzed to cysteine, alpha-ketobutyrate and ammonia b
269 c18 is released from the membrane when PA is hydrolyzed to diacylglycerol by the PA phosphatase Pah1.
271 We have shown previously that oxetanes are hydrolyzed to diols by human microsomal epoxide hydrolas
272 yclic substrate into a succinimide, which is hydrolyzed to generate an Asp or isoAsp containing pepti
276 xed by-product of different fish species was hydrolyzed to obtain peptide fractions and evaluate thei
277 formation of the acid anhydride, which also hydrolyzes to regenerate the acid, although a minor chan
278 ) transporters are the largest family of ATP-hydrolyzing transporters, which import or export substra
280 ocused on damaging adipocyte cell membranes, hydrolyzing triglycerides (TGs), or inducing apoptosis.
281 a crucial role in preventing dyslipidemia by hydrolyzing triglycerides from packaged lipoproteins.
283 nalyses reveal that proofreading activity to hydrolyze Tyr-tRNA(Phe) is increased during oxidative st
284 e boron-containing ODH catalysts oxidize and hydrolyze under reaction conditions, forming an amorphou
285 istine BN materials are readily oxidized and hydrolyzed under ODH reaction conditions to yield a phas
286 roorganisms containing urease enzymes, which hydrolyze urea and enable carbonate ions to become avail
287 and the prevalence of the urease enzyme that hydrolyzes urea, minerals readily precipitate in nonwate
288 ry HP-G by MSI-CE-MS/MS as compared to total hydrolyzed urinary HP by GC-MS due to the low residual l
291 Muscle and skin samples of both species were hydrolyzed using two enzymes, Alcalase 2.4 L(R) or Prota
292 es in model systems containing enzymatically hydrolyzed whey protein under dry heating conditions was
293 a (IF) containing hydrolyzed and intact (non-hydrolyzed) whey protein in their composition were inves
294 , whole crickets (Gryllodes sigillatus) were hydrolyzed with alcalase at 0.5, 1.5, and 3.0% (w/w) for
296 t the eight hydrolysates, Viscozyme-proteins hydrolyzed with Papain showed the highest ability to que
297 rbohydrases, Viscozyme or Cellulase and then hydrolyzed with proteases (Alcalase, Papain, Protamex, F
298 ted steroids in the aqueous medium were then hydrolyzed with sulfatase and extracted with hexane.
299 s-linked and hydroxypropylated starches were hydrolyzed with this improved acid method, and the resul
300 lity of the metal separately by cysteine and hydrolyzed zinc(II), and synergistically by the combinat