ライフサイエンスコーパス: hydroxyethyl

1 rdination between A20 and coralyne in a 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) bu

2 strong copper binding was observed for 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES), 4

3 heating in a sodium acetate buffer and 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid buffer, re

4 l enhancement at 48 mT, is demonstrated on 2-hydroxyethyl-1-(13)C-propionate-d(2,3,3) using a double-

5 attached to the SWNT by esterification of 2-hydroxyethyl 2'-bromopropionate with carboxylic acid gro

6 S-benzyl phenylmethanethiosulfinate and S-(2-hydroxyethyl) 2-hydroxyethanethiosulfinate, respectively

7 K(i) = 389 +/- 72 nM), and (S)-N-(1-methyl-2-hydroxyethyl)-2-(R)-methyl-arachidonamide (K(i) = 233 +/

8 ethyl anandamide analogues (R)-N-(1-methyl-2-hydroxyethyl)-2-(R)-methyl-arachidonamide (K(i) = 7.42 +

9 (K(i) = 7.42 +/- 0.86 nM), (R)-N-(1-methyl-2-hydroxyethyl)-2-(S)-methyl-arachidonamide (K(i) = 185 +/

10 de (K(i) = 185 +/- 12 nM), (S)-N-(1-methyl-2-hydroxyethyl)-2-(S)-methyl-arachidonamide (K(i) = 389 +/

11 lecule inhibitor of tau fibrillization, 3-(2-hydroxyethyl)-2-[2-[[3-(2-hydroxyethyl)-5-methoxy-2-benz

12 omolar inhibitory potency: N-hydroxy-4-[(N(2-hydroxyethyl)-2-phenylacetamido)methyl)-benzamide)] (HPB

13 amycin (17AAG), and (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl

14 a-2'-deoxyguanosine as the analogues of N(7)-hydroxyethyl-2'-deoxyguanosine and N(7)-oxoethyl-2'-deox

15 pared by deamination of 3',5'-protected O(6)-hydroxyethyl-2'-deoxyguanosine followed by cyclization t

16 utative structure for diplopyrone {6-[(1S)-1-hydroxyethyl]-2,4a(S),6(R),8a(S)-tetrahydropyran[3,2-b]p

17 4, ethyl 16 and 35, hydroxymethyl 20 and 41, hydroxyethyl 22, fluoroethyl 23, hydroxypropyl 27, and f

18 revealed it to be 2-amino-4-(2-hydroxy-3-(2-hydroxyethyl)-2H-benzo[b][1,4]oxazin-5-yl)-4-oxobutanoi

19 rocinnamyl)-N-methylaminomethyl]phenyl]-N-(2-hydroxyethyl) -4-methoxybenzenesulfonamide) also suppres

20 s with the paraquat derivative N,N'-bis(beta-hydroxyethyl)-4,4'-bipyridinium bis(hexafluorophosphate)

21 N-Boc syn-7-(2-hydroxyethyl)-4-(alkyl or aryl)sulfonyl-2-azabicyclo[2.2

22 hexen-1-yl)-1E,3E,5E,7E-octatet raenyl]-1-(2-hydroxyethyl)-4-[4-methyl-6-(2,6,6-trimethyl-1-cyclohexe

23 rocinnamyl)-N-methylaminomethyl]phenyl]-N-(2-hydroxyethyl)-4-meth oxybenzenesulfonamide phosphate sal

24 prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide).

25 des with N-(4-hydroxy-2-methylenebutyl)-N-(2-hydroxyethyl)-4-methylbenzenesulfonamide has been develo

26 hyl)-2-methylpyrimidine pyrophosphate and 5-(hydroxyethyl)-4-methylthiazole phosphate.

27 been characterized as the ADP adduct of 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid.

28 of benzaldehyde, catalyzed by 3-benzyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide in methanol buf

29 The synthesis of a series of 3-beta-hydroxyethyl-4-arylquinolin-2-ones is described.

30 ethylpyrimidine pyrophosphate (HMP-PP) and 5-hydroxyethyl-4-methylthiazole phosphate (THZ-P) moieties

31 R)-2-((1R,2R)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothi azolone), which displays

32 no]carbonyl]-3-pyrrolidinyl ]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-e

33 le-1-yl)heptane phosphonate) and YM 50201 (3-hydroxyethyl 5,3'-thiophenyl pyridine) strongly inhibite

34 brillization, 3-(2-hydroxyethyl)-2-[2-[[3-(2-hydroxyethyl)-5-methoxy-2-benzothiazolylide ne]methyl]-1

35 hibitor of tau fibrillization, 3,3'-bis(beta-hydroxyethyl)-9-ethyl-5,5'-dimethoxythiacarbocyanine iod

36 We report the design and synthesis of N(7)-hydroxyethyl-9-deaza-2'-deoxyguanosine and N(7)-oxoethyl

37 M6P and mannose 6-phosphate-poly[N-(2-hydroxyethyl)-acrylamide] (M6P-PAA) inhibited the infect

38 crylamide, poly(ethylene glycol) acrylate, 2-hydroxyethyl acrylate (HEA), and an acrylamido glyco mon

39 he formation of hydroxyethyl propionate from hydroxyethyl acrylate and ethyl acetate from vinyl aceta

40 esis of a copolymer containing quinine and 2-hydroxyethyl acrylate that effectively compacts plasmid

41 ns of poly(tert-butyl acrylate)-block-poly(2-hydroxyethyl acrylate), yielding poly(tert-butyl acrylat

42 Rigid poly[hydroxyethyl acrylate-co-poly(ethylene glycol) diacrylat

43 AdaGb(3) (but not hydroxyethyl adaGb(3)) incorporation into Gb(3)-positive

44 CarboxyadaGb(3), urea-adaGb(3), and hydroxyethyl adaGb(3), preferentially bound by VT2, also

45 Two radicals were detected: the PBN-1-hydroxyethyl adduct and the tert-butyl aminoxyl radical.

46 A 2-hydroxyethyl adduct was found by mass spectrometry to be

47 pyridyl-1-oxide)-N-t-butylnitrone (4-POBN)-1-hydroxyethyl adducts under normal wine storage condition

48 Migration of N,N-Bis(2-hydroxyethyl) alkyl(C8-C18)amines from five different po

49 A series of potent hydroxyethyl amine (HEA) derived inhibitors of beta-site

50 NA to produce N-[2-(N7-guaninyl) ethyl]-N-[2-hydroxyethyl]-amine (G-NOR-OH) monoadducts and N,N-bis[2

51 monoamine analogues, which features a bis(2-hydroxyethyl)amino group in the side chain, proved to be

52 derivatives, MJ-III-65 (NSC 706744; 6-[3-(2-hydroxyethyl)amino-1-propyl]-5,6-dihydro-2,3-dimethoxy-8

53 ternating pi-electron layers of 4-[[4-[bis(2-hydroxyethyl)amino]phenyl]diazenyl]-1-[4-(diethoxyphosph

54 ((+/-)-(R*,R*)-[4-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy] acetic acid sodium hy

55 3 [disodium (RR)-5-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino]propyl]-1,3-benzodiox azole-2,2-dica

56 oisoquinoline MJ-III-65 (NSC 706744, 6-[3-(2-hydroxyethyl)aminopropyl]-5,6-dihydro-5,11-diketo-2,3-di

57 phate), and two protic ionic liquids, (bis(2-hydroxyethyl)ammonium acetate and triethylammonium aceta

58 he potential of (18)F-fluoromethyldimethyl-2-hydroxyethyl-ammonium (FCH) PET/CT in the detection of r

59 o-carrier-added [18F]fluoromethyl-dimethyl-2-hydroxyethyl-ammonium (FCH), was synthesized through the

60 X-ray structures of a C-2 hydroxyethyl analogue in complex with both JAK1 and JAK2

61 der reactions of chiral 9-methoxyethyl and 9-hydroxyethyl anthracene have been investigated both expe

62 ive formation of chiral 2-(2,2,2-trifluoro-1-hydroxyethyl)azetidines via trifluoromethylation through

63 orophyllide a hydratase (BchF) followed by 3-hydroxyethyl bacteriochlorophyllide a dehydrogenase (Bch

64 Stereoisomers of 4-(1-hydroxyethyl)benzene and 4-(1,2-dihydroxyethyl)benzene m

65 While compounds with the 4-(1-hydroxyethyl)benzene P2' moiety maintained excellent ant

66 rovided the corresponding free-base 10(3)-(2-hydroxyethyl)benzochlorin, which upon a sequence of reac

67 converted to a mixture of predominantly 4-(1-hydroxyethyl)-benzoic acid and 4-vinylbenzoic acid, the

68 ibes the effect of urea on the properties of hydroxyethyl cellulose (HEC) polymer solutions used for

69 The two networks interact through hydroxyethyl cellulose adsorption to the nanofibrillated

70 hydrogel consists of naphthyl-functionalized hydroxyethyl cellulose and a cationic polystyrene deriva

71 fted silica nanoparticles, a semicrystalline hydroxyethyl cellulose derivative, and cucurbit[8]uril u

72 netration of dexamethasone from an ethanolic hydroxyethyl cellulose gel into ex vivo human skin, muri

73 he aqueous phase was gelled by incorporating hydroxyethyl cellulose.

74 Ethyl(hydroxyethyl)cellulose was functionalized with Brooker's

75 s broadened in vitro activity, the chlorin 3-hydroxyethyl chlorophyllide a was newly identified as a

76 The primary alcohol 2-hydroxyethyl-CoM was a substrate for both R-HPCDH and S-

77 abolite identified by mass spectrometry as 2-hydroxyethyl-CoM was produced from epoxyethane.

78 prepared from key trioxane alcohol 10beta-(2-hydroxyethyl)deoxoartemisinin (9b).

79 were diluted with sample buffer containing 2-hydroxyethyl disulfide (2-HED) (1:3) or were cup-loaded

80 tivities that are typical for glutaredoxins, hydroxyethyl disulfide reduction and electron donation t

81 ivity was assayed with a synthetic substrate hydroxyethyl disulfide.

82 iple by-product is the organic sulphide 5-(2-hydroxyethyl)dithiazine.

83 ries out the condensation of pyruvate as a 2-hydroxyethyl donor with d-glyceraldehyde-3-phosphate (d-

84 otection against inactivation provided by S-(hydroxyethyl)ethacrynic acid indicates that MOI reacts i

85 where L(1) is N-(salicylideneaminato)-N'-(2-hydroxyethyl)ethane-1,2-diamine and L(2) is 3,5-di-tert-

86 tions of N-(2-hydroxyethyl) glycine (HeGly), hydroxyethyl-ethylenediamine (HEEDA), and DEA, secondary

87 -1,2-cyclohexanediaminetetracetic acid, N-(2-hydroxyethyl)ethylenediaminetriacetic acid, trimethylene

88 The hydroxyethyl flip results in both the decreased basicity

89 rmore, that MHETase does not turnover mono(2-hydroxyethyl)-furanoate or mono(2-hydroxyethyl)-isophtha

90 An orthogonally protected 2'-hydroxyethyl GlcN derivative was immobilized on a trityl

91 was blended with low concentrations of N-(2-hydroxyethyl) glycine (HeGly), hydroxyethyl-ethylenediam

92 itrosodiethanolamine (NDELA), and nitroso-(2-hydroxyethyl) glycine (NHeGly) were measured over a rang

93 3-fold relative to the acyclic analogue N-(2-hydroxyethyl)glycine amide ( 3).

94 n the discovery of Suggs and Pires that N-(2-hydroxyethyl)glycine amides undergo rapid amide cleavage

95 by coupling PEG to [(N-2-naphthalenyl)-2-(2-hydroxyethyl)]-glycine-2-[(3,5-dibromo-2,4-dihydr oxyphe

96 mitting rotation of the carbapenem 6alpha-1R-hydroxyethyl group and abolishing this contact.

97 nd also suggest that elimination of the C(6) hydroxyethyl group by retroaldolic reaction leads to a s

98 acylenzyme complex, the meropenem 6alpha-1R-hydroxyethyl group interacts with Asn132, but not with t

99 f the vinyl side chains of the former with a hydroxyethyl group of the latter.

100 yll a biosynthesis requires formation of a 3-hydroxyethyl group on pyrrole ring A that gets subsequen

101 tion leads to the flipping of the carbapenem hydroxyethyl group to hydrogen bond to carboxyl O2 of Gl

102 C-4a-hydroperoxide functionality, and a beta-hydroxyethyl group to model the effect of the 2'-OH grou

103 ns of both (R)- and (S)-stereoisomers of the hydroxyethyl group with Asp30'.

104 t carbapenem and carbapenem lacking the C(6) hydroxyethyl group.

105 m(III) macrocyclic complexes having appended hydroxyethyl groups were investigated.

106 DNA adduct formed by VC, was reduced to 7-(2-hydroxyethyl)guanine and measured by liquid chromatograp

107 ining O6-methyl, -benzyl, -4-bromothenyl or -hydroxyethyl-guanine but does not remove the alkyl group

108 During the reaction between 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulphide,

109 ar reaction proportions between 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulphide,

110 nt, and there is some unreacted 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine remaining; the only so

111 5-carboxamides into the hydroxyethylene and (hydroxyethyl)hydrazine dipeptide isosteres as P2 and P2'

112 red from 1-[2-(oleoyloxy)ethyl]-2-oleyl-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM)/dioleoylphos

113 s,trans-1,3,5-cyclohexanetriol, 1,3,5-tris(2-hydroxyethyl)isocyanurate, tetraethyleneglycol, and hexa

114 ver mono(2-hydroxyethyl)-furanoate or mono(2-hydroxyethyl)-isophthalate.

115 eparation of (beta,beta,beta-trifluoro-alpha-hydroxyethyl)isoxazoles.

116 pounds S-benzyl-l-cysteine sulfoxide and S-2-hydroxyethyl-l-cysteine sulfoxide.

117 A new gel-forming monomer, 2-(hydroxyethyl) methacrylamide (HEMAA), was used.

118 mass ratio of 1:1 (PE); and PE plus 10% of 2-hydroxyethyl methacrylate (HEMA) and 5% of bisphenol A g

119 2-Hydroxyethyl methacrylate (HEMA) and glycidyl methacryla

120 We polymerized hydroxyethyl methacrylate (HEMA) around the CCA to form

121 methacrylate (DMAEMA), in combination with 2-hydroxyethyl methacrylate (HEMA) as functional monomers,

122 ethacryloyl-L-histidine methylester (MAH), 2-Hydroxyethyl methacrylate (HEMA) as monomers and ethylen

123 crylate, a result that was not observed in a hydroxyethyl methacrylate (HEMA) homopolymer or in netwo

124 Mechanisms by which the resin monomer 2-hydroxyethyl methacrylate (HEMA) induces hypersensitivit

125 This initiator was employed in the ATRP of 2-hydroxyethyl methacrylate (HEMA), and kinetic studies in

126 uced to undergo cell death when exposed to 2-hydroxyethyl methacrylate (HEMA).

127 HEMA/BisGMA neat resins containing 45 wt% 2-hydroxyethyl methacrylate (HEMA).

128 rticles in the lens material, such as poly-2-hydroxyethyl methacrylate (p-HEMA) hydrogels.

129 hacrylate with ethylene dimethacrylate, or 2-hydroxyethyl methacrylate and [2-(methacryloyloxy)ethyl]

130 Using the same catalyst, polymerization of 2-hydroxyethyl methacrylate and methyl methacrylate yielde

131 Copolymers of hydroxyethyl methacrylate and styrene sulfonate complex

132 hers were synthesized and copolymerized with hydroxyethyl methacrylate and the cross-linker ethylene

133 lamido-2-methyl-1-propanesulfonic acid and 2-hydroxyethyl methacrylate carried out through a mask aff

134 , N,N-dimethylaminoethyl methacrylate, and 2-hydroxyethyl methacrylate lead to the introduction of co

135 with a photo-cross-linkable polypeptide of 2-hydroxyethyl methacrylate modified poly(gamma-glutamic a

136 lamido-2-methyl-1-propanesulfonic acid and 2-hydroxyethyl methacrylate on top of the generic hydropho

137 hacrylate polymer segment into a hydrophilic hydroxyethyl methacrylate structure.

138 Hyaluronic acid was chemically modified with hydroxyethyl methacrylate to form hydrolytically degrada

139 o polymer brushes: hydroxy-functional poly(2-hydroxyethyl methacrylate) (pHEMA) and carboxy-functiona

140 rs subsequently triggered the growth of poly(hydroxyethyl methacrylate) (PHEMA) at the end of immobil

141 the preparation of electrode-tethered poly(2-hydroxyethyl methacrylate) (pHEMA) brushes of well-defin

142 orption/ionization plates coated with poly(2-hydroxyethyl methacrylate) (PHEMA) brushes that are deri

143 actic-co-glycolic) acid (PLGA) films in poly(hydroxyethyl methacrylate) (pHEMA) by ultraviolet photop

144 integration of hydroxyapatite with a poly(2-hydroxyethyl methacrylate) (pHEMA) hydrogel scaffold.

145 Linear poly(2-hydroxyethyl methacrylate) (PHEMA) polymers were synthes

146 of poly(methyl methacrylate) (PMMA), poly(2-hydroxyethyl methacrylate) (PHEMA), and trifluoroacetic

147 2-aminoethyl methacrylate hydrochloride-co-2-hydroxyethyl methacrylate) (poly(AMA-co-HEMA)) was first

148 trifluoroacetic anhydride-derivatized poly(2-hydroxyethyl methacrylate) (TFAA-PHEMA) on silicon subst

149 ll adhesion, whereas unfunctionalized poly(2-hydroxyethyl methacrylate) did not.

150 on of SNP-Ply500 conjugates into a thin poly(hydroxyethyl methacrylate) film; and affinity binding to

151 dimethyl sulfoxide (DMSO)-compatible poly(2-hydroxyethyl methacrylate) gels and sample setup with a

152 lyzed milk samples, an interface with poly(2-hydroxyethyl methacrylate) p(HEMA) brush was employed.

153 The glass was treated with poly(2-hydroxyethyl methacrylate) to control cell adherence.

154 (a stabilizer) and Hydron (poly-HEMA (poly(2-hydroxyethyl methacrylate)) to allow slow release).

155 materials, as well as copolymers of poly (2-hydroxyethyl methacrylate), have shown promise in approa

156 a dehydrated hydrogel of the polymer poly(2-hydroxyethyl methacrylate), which is then recovered usin

157 cytes (HFCs) were cultured either on poly-(2-hydroxyethyl methacrylate)-coated plates (differentiated

158 ve synthesized a GRGDS-functionalized poly(2-hydroxyethyl methacrylate).

159 antifouling hydrogel coatings, composed of 2-hydroxyethyl methacrylate, vinylpyrrolidinone, and poly(

160 s in suspension on plates coated with poly-2-hydroxyethyl methacrylate, which blocks access to the EC

161 oparticles were incorporated into the poly(2-hydroxyethyl methacrylate-co-ethylene dimethacrylate) mo

162 A poly(hydroxyethyl methacrylate-co-methacrylic acid) holograph

163 Microtemplating is used to shape poly(2-hydroxyethyl methacrylate-co-methacrylic acid) hydrogel

164 nate (PEDOT:PSS) nanomaterials within poly(2-hydroxyethyl methacrylate-co-polyethyleneglycol methacry

165 rdein digestion and biologic effects of poly(hydroxyethyl methacrylate-co-styrene sulfonate (P(HEMA-c

166 by demonstrating decreased survival on poly-hydroxyethyl methacrylate-coated dishes.

167 cell-matrix adhesion was reduced (in poly(2-hydroxyethyl methacrylate-coated plates), IGF1 induced i

168 lance (QCM) nanosensor, LOV imprinted poly(2-hydroxyethyl methacrylate-methacryloylamidoaspartic acid

169 site was developed in the presence of poly(2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid

170 Then, CIT-imprinted poly(2-hydroxyethyl methacrylate-methacryloylamidoglutamic acid

171 transfer radical polymerization (ATRP) of 2-hydroxyethyl methacrylate.

172 ethylene dimethacrylate, and acrylamide or 2-hydroxyethyl methacrylate.

173 n, sodium fluorescein, and theophylline in 2-hydroxyethyl methacrylate/methacrylic acid (HEMA/MAA) co

174 s containing test compounds with pHEMA (poly[hydroxyethyl methacrylate]) by ultraviolet light polymer

175 , Kd=57 mM) by a covering membrane of poly(2-hydroxyethyl) methacrylate.

176 yrene, poly(methyl methacrylate), and poly(2-hydroxyethyl)methacrylate were grown with controlled thi

177 -oxypropoxy)-phenyl]-propane (Bis-GMA) and 2-hydroxyethyl-methacrylate (HEMA)-and have equivalent/imp

178 A poly(2-hydroxyethyl-methacrylate) (pHEMA) hydrogel was develope

179 by transfer to suspension culture on poly-(2-hydroxyethyl-methacrylate) (polyHEMA)-coated dishes.

180 s, as well as a short middle block of poly(2-hydroxyethyl methacrylates) (PHEMA) that is randomly fun

181 thyl methanethiosulfonate, but not neutral 2-hydroxyethyl methanethiosulfonate, positively charged 2-

182 tic decomposition to the expected alcohol, 2-hydroxyethyl methyl phosphate, and the 2-nitrosoacetophe

183 The alcohol of the 6alpha hydroxyethyl moiety is directed away from the general ba

184 a hydrogen bond to the alcohol of the 6alpha-hydroxyethyl moiety of doripenem.

185 rt on the structure-based discovery of a C-2 hydroxyethyl moiety which provided consistently high lev

186 rted, this key water is not displaced by the hydroxyethyl moiety.

187 of the central mannose unit is replaced by a hydroxyethyl moiety.

188 l-1-oxo-10-carbo xylate (K-252a) and 2-[N-(2-hydroxyethyl)-N-(4-methoxybenzenesulfonyl)]amino-N-(4-ch

189 the formation of N-(2-aminoethyl)- and N-(2-hydroxyethyl)-N-nitrosoformamides 15 and 16, respectivel

190 was blocked by the CaMKII inhibitor 2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-c

191 er cdk5 by roscovitine or of CaMK by 2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-c

192 ely blocked by the CaMKII inhibitor, 2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-c

193 by two doses of the CAMKII inhibitor 2-(N-[2-hydroxyethyl])-N-(4-methoxybenzenesulfonyl)amino-N-(4-ch

194 The 2'-O-(2-hydroxyethyl) nucleosides were converted, in excellent y

195 erfluorooctanamide (MeFOAE) and N-ethyl-N-(2-hydroxyethyl)perfluorooctanamide (EtFOAE), were not dete

196 Two disubstituted PFAMs, N-methyl-N-(2-hydroxyethyl)perfluorooctanamide (MeFOAE) and N-ethyl-N-

197 the rate of oxidation of the substrate 10-(2-hydroxyethyl)phenoxazine, varied over 2 orders of magnit

198 uoromethoxy-phenyl)urea (3FMTDZ) and 1-[2-(2-hydroxyethyl)phenyl]-3-(1,2,3-thiadiazol-5-yl)urea (HETD

199 acid-based small-molecule N-hydroxy-4-(2-[(2-hydroxyethyl)(phenyl)amino]-2-oxoethyl)benzamide (HPOB)

200 mus catalyses the biosynthesis of MPn from 2-hydroxyethyl phosphonate and the bacterial C-P lyase com

201 s, the reduction of phosphonoacetaldehyde to hydroxyethyl-phosphonate may represent a common step in

202 contain an unexpected common intermediate, 2-hydroxyethyl-phosphonate, which is synthesized from phos

203 rain-permeable iron chelator, VK-28 [5-(4-(2-hydroxyethyl) piperazin-1-yl (methyl)-8-hydroxyquinoline

204 culminated in the identification of 3-[4-(2-hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1

205 phase, which contains an organic alkali 1-(2-hydroxyethyl) piperazine (HEP), is used for CO2 absorpti

206 protonation of 2-NO(2)() by piperazine, 1-(2-hydroxyethyl)piperazine, and morpholine in the same solv

207 that for the reactions with piperazine, 1-(2-hydroxyethyl)piperazine, and morpholine it is deprotonat

208 -piperazineethanesulfonic acid (HEPES), 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (HEPPS),

209 (68)Ga labeling was performed in N-(2-hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid) buffe

210 ine-1-propanesulfonic acid (HEPPS), and N-(2-hydroxyethyl)piperazine-N'-(2-hydroxypropanesulfonic aci

211 ve inhibitor of this enzyme, as well as N-(2-hydroxyethyl)piperazine-N'-2-ethanesulfonic acid (HEPES)

212 article describes the identification of 1-(2-hydroxyethyl)-piperazine as a new, cost-effective, highl

213 n unidentified ligand resembling Hepes (N-[2-hydroxyethyl]piperazine-N'-[2-ethanesulfonic acid]).

214 -2-chlorophenoxazine (10B) and 10-[4'-[(beta-hydroxyethyl)piperazino]butyl]-2-chlorophenoxazine (15B)

215 2 and 0.2% are achieved for the formation of hydroxyethyl propionate from hydroxyethyl acrylate and e

216 ulted in a (1) H polarization of P=0.25% for hydroxyethyl propionate, a known contrast agent for magn

217 effects of DNA damaging agents that generate hydroxyethyl, propyl, and hydroxypropyl adducts.

218 an iron(II) catalyst assembled by a hindered hydroxyethyl-pybox ligand, is described.

219 quent iodination of the 4-(2,2,2-trifluoro-1-hydroxyethyl)pyrazole intermediate.

220 with 2-(hydroxymethyl)pyridine (hmpH) or 2-(hydroxyethyl)pyridine (hepH) gives the Mn(II)(2)Mn(III)(

221 2ClO(4) (1) containing bidentate (hep-H=2-(2-hydroxyethyl)pyridine) ligand was synthesized and charac

222 6-[(2R,5R)-2-methyl-5-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl]-4-trif luoromethylquinolin

223 an antibiotic, 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione (C(12)-TA), derived f

224 dation product, 3-(1-hydroxydecylidene)-5-(2-hydroxyethyl)pyrrolidine-2,4-dione, are potent antibacte

225 y 60% of total adducts were due to the alpha-hydroxyethyl radical adduct.

226 gainst the toxicity of superoxide anions and hydroxyethyl radicals in HepG2 cells and in a mouse mode

227 ducts of acetaldehyde, other aldehydes and 1-hydroxyethyl radicals; and activation of Kupffer cells b

228 Three groups (n = 5) received 40-O-(2-hydroxyethyl)-rapamycin (RAD, 2.5 mg/kg/d, by gavage): G

229 We have tested rapamycin and RAD001 [40-O-(2-hydroxyethyl)-rapamycin], both mammalian target of rapam

230 ontrast, addition of cyclosporine or 40-O-[2-Hydroxyethyl]rapamycin did not significantly increase gr

231 These inhibitors feature a hydroxyethyl secondary amine isostere and a novel aromat

232 ystal structure of BACE in complex with this hydroxyethyl secondary amine isostere inhibitor is also

233 log of the natural trisaccharide, in which a hydroxyethyl side chain replaces the hydroxyl group at t

234 Based on the kinetic study of POBN-1-hydroxyethyl spin adduct (POBN-1-HER) formation in wines

235 roups and then hemodiluted by exchange of 6% hydroxyethyl starch (130,000:0.4) for whole blood to the

236 eive either 7.2% saline/6% hypertonic saline hydroxyethyl starch (4 mL/kg) or vehicle (NaCl 0.9 %) af

237 is study evaluated whether administration of hydroxyethyl starch (HES) 130/0.4 affects coagulation co

238 Hydroxyethyl starch (HES) [corrected] is widely used for

239 The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have n

240 known if use of colloid solutions containing hydroxyethyl starch (HES) to correct for intravascular d

241 on in the caudal vein of albumin, saline, or hydroxyethyl starch (HES).

242 effects of intravenous administration of 6% hydroxyethyl starch (maize-derived) in 0.9% saline (Volu

243 renal replacement therapy was greater after hydroxyethyl starch (odds ratio, 2.29; 95% CI, 1.47-3.60

244 Kingdom) and a "balanced" preparation of 6% hydroxyethyl starch (potato-derived) [Plasma Volume Redi

245 py directed at preset hemodynamic goals with hydroxyethyl starch (predominantly 6% hydroxyethyl starc

246 ICU directed at preset hemodynamic goals: 1) hydroxyethyl starch (predominantly 6% hydroxyethyl starc

247 < 0.001), 32.9+/-4.3 and 29.5+/-4.4mL/kg for hydroxyethyl starch 130/0.4 (p < 0.05), 31.8+/-3.9 and 2

248 ls: 1) hydroxyethyl starch (predominantly 6% hydroxyethyl starch 130/0.4) in 2004-2006, n = 2,137; 2)

249 s with hydroxyethyl starch (predominantly 6% hydroxyethyl starch 130/0.4) in the first period, 4% gel

250 hich was not influenced by hypertonic saline hydroxyethyl starch administration.

251 Both low molecular weight hydroxyethyl starch and gelatin may impair renal functio

252 ater use of renal replacement therapy in the hydroxyethyl starch and gelatin periods compared to the

253 Hydroxyethyl starch and gelatin were independent risk fa

254 Resuscitation comprised hydroxyethyl starch and norepinenephrine infusion titrat

255 Resuscitation comprised of hydroxyethyl starch and norepinephrine infusion titrated

256 Resuscitation with hydroxyethyl starch and sham treatment significantly dec

257 Clinical trials of hydroxyethyl starch are conflicting.

258 s are shown to be a suitable replacement for hydroxyethyl starch as a extracellular matrix for red bl

259 requiring acute volume resuscitation, use of hydroxyethyl starch compared with other resuscitation so

260 ypertonic solutions, it is hypothesized that hydroxyethyl starch enhances cerebral blood flow and imp

261 er models of brain injury, hypertonic saline hydroxyethyl starch failed to improve the outcome when a

262 Clinical use of hydroxyethyl starch for acute volume resuscitation is no

263 This might explain why hypertonic saline hydroxyethyl starch has failed to improve outcome in the

264 Hydroxyethyl starch is commonly used for volume resuscit

265 Hydroxyethyl starch is no longer recommended, and debate

266 comparable at baseline in all study periods (hydroxyethyl starch n = 360, gelatin n = 352, only cryst

267 ocortex with no effects of hypertonic saline hydroxyethyl starch on neuronal survival.

268 Total fluid requirement was 163 mL/kg in the hydroxyethyl starch period, 207 mL/kg in the gelatin per

269 from SCT products was not possible by using hydroxyethyl starch sedimentation but was achievable wit

270 f blood volume using a high-molecular-weight hydroxyethyl starch solution (Hextend, Hospira, MW 670 k

271 We included 38 eligible trials comparing hydroxyethyl starch to crystalloids, albumin, or gelatin

272 Hypertonic saline hydroxyethyl starch treatment resulted in an accentuated

273 r death among patients randomized to receive hydroxyethyl starch was 1.07 (95% CI, 1.00 to 1.14; I2,

274 retracted because of scientific misconduct, hydroxyethyl starch was associated with a significant in

275 d these 7 trials that involved 590 patients, hydroxyethyl starch was found to be associated with incr

276 me expanders tested (e.g., dextran, gelatin, hydroxyethyl starch, and hypertonic saline).

277 preserved using 5% dimethyl sulfoxide and 6% hydroxyethyl starch.

278 is observed that matches the performance of hydroxyethyl starch.

279 nding properties of the 2 preparations of 6% hydroxyethyl starch.

280 d group (fluid ratios 1.4:1 [crystalloids to hydroxyethyl starch] and 1.1:1 [crystalloids to gelatin]

281 data are available concerning the impact of hydroxyethyl starches and saline on pulmonary microperfu

282 Colloids (n = 1414; gelatins, dextrans, hydroxyethyl starches, or 4% or 20% of albumin) or cryst

283 Conjugates possessing bis(2-hydroxyethyl)stilbene 4,4'-diether linkers form the most

284 Synthetic conjugates possessing bis(2-hydroxyethyl)stilbene-4,4'-diether linkers (Sd2) form th

285 stituent (ZnPc-S16) and the other with the 2-hydroxyethyl substituent (EtOH-S4), were synthesized to

286 ation of the deacylating water by the 6alpha-hydroxyethyl substituent of carbapenems.

287 by interaction with the carbapenem 6alpha-1R-hydroxyethyl substituent.

288 -lactamase-catalyzed elimination of the C(6) hydroxyethyl substituent.

289 ne bearing a 5-endo-[2,2-bis(trifluoromethyl)hydroxyethyl] substituent is reported.

290 ynthetic strategies were explored to prepare hydroxyethyl substituted piperazines with different subs

291 iberating soluble products, including mono(2-hydroxyethyl) terephthalate (MHET), which is cleaved to

292 In addition, an intermediary monomer, bis(2-hydroxyethyl)terephthalate, was found but only in PET-bo

293 The PFOR reaction includes a hydroxyethyl-thiamin pyrophosphate (HE-TPP) radical inte

294 derivatives and its precursors 4-methyl-5-(2-hydroxyethyl) thiazole (HET) and 4-amino-2-methyl-5-hydr

295 e catalyzes the coupling of 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate (Thz-P) and 4-amino-5-(h

296 red for the synthesis of the 4-methyl-5-beta hydroxyethyl-thiazole monophosphate moiety of TPP.

297 6,6-Dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzoth

298 In particular, 6,6-dimethyl-3-(2-hydroxyethyl)thio-1-(thiazol-2-yl)-6,7-dihydro-2-benzoth

299 (Hydroxyethyl)urea peptidomimetics systematically altered

300 oxidases, we incorporated Fe(III)-2,4 (4,2) hydroxyethyl vinyl deuterioporphyrin IX, as a heme o mim