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1 ctated by both the sugar conformation and 2'-hydroxyl group.
2 s achieved with the substrate bearing a free hydroxyl group.
3 r connecting the metal chelating unit to the hydroxyl group.
4 the stereogenic center bearing the secondary hydroxyl group.
5 ng a side-arm and a potentially nucleophilic hydroxyl group.
6 phile by a hydrogen bond from the catalyst's hydroxyl group.
7 vel polar interaction mediated by the RJW100 hydroxyl group.
8 cid adenine dinucleotide at the adenosine 3'-hydroxyl group.
9 e ring to substitute the amino group with an hydroxyl group.
10 ies on the carbon position of the acyl chain hydroxyl group.
11 at funnels to its narrowest region at the C3-hydroxyl group.
12 the resulting primer strand lacks a terminal hydroxyl group.
13 artially localized on the protonated support hydroxyl group.
14 all-trans trienes separated by a stereogenic hydroxyl group.
15 followed by the allyl group and next by the hydroxyl group.
16 ase yielding an intermediate with a tertiary hydroxyl-group.
17 acyl, alkoxycarbonyl, nitro, cyano, and even hydroxyl groups.
18 avenging activity, due to the high number of hydroxyl groups.
19 s a carboxyl head group and GMS has two free hydroxyl groups.
20 ction processing of substrates with inverted hydroxyl groups.
21 thiiranium ions in competition with phenolic hydroxyl groups.
22 especially those that lack adjacent aromatic hydroxyl groups.
23 saccharides, and saccharides containing free hydroxyl groups.
24 f detected metabolites were those containing hydroxyl groups.
25 s acidic surface domains depleted in surface hydroxyl groups.
26 ,3-dioxane structures with lignin side-chain hydroxyl groups.
27 hydration or the number of crystallographic hydroxyl groups.
28 f kanamycin B analogues alkylated at various hydroxyl groups.
29 undergo acid-base chemistry with the silica hydroxyl groups.
30 ties, when the glycan moieties contain axial hydroxyl groups.
31 to be chemically bound to compounds with cis-hydroxyl groups.
32 phery that is functionalized by sulfonic and hydroxyl groups.
33 oups including keto, ester, amino, halo, and hydroxyl groups.
34 culate the content of the different types of hydroxyl groups.
36 s hexaketide with an epimerized nucleophilic hydroxyl group allowed for direct evaluation of the subs
38 cacy for the selective oxidation of a single hydroxyl group among many in unprotected polyol natural
39 udy, we examined whether the distribution of hydroxyl groups among flavones could influence their pot
42 se only compounds that contain a carboxyl or hydroxyl group and have moderate steric hindrance were e
43 tabilized by hydrogen bonds between the 5-HT hydroxyl group and lipid headgroups and allows 5-HT to i
44 xtensive interactions between each trehalose hydroxyl group and residues of the cap and core domains
46 of the propeptide by deprotonating the Thr1 hydroxyl group and that both residues together with Asp1
48 the noncovalent interaction of the substrate hydroxyl group and the chiral cationic palladium catalys
49 duct selectivity originating from a resident hydroxyl group and the critical choice of the reaction s
51 duces ligand formation between oxygen on the hydroxyl group and the zinc ions, which expands the stab
52 ning initiated by the attack of one phenolic hydroxyl group and, then, by addition of one aromatic ph
55 sence of other functionalities, such as free hydroxyl groups and amines widely present in biological
56 Carrageenan, which has a large number of hydroxyl groups and is fully negatively charged, is a ne
57 strategy enables direct introduction of key hydroxyl groups and rapid construction of key bonds and
58 wever, fast proton exchange between bridging hydroxyl groups and water occurs even in the presence of
59 eroid "reduced pregnenolone" (containing two hydroxyl groups) and its d4-analogue provide evidence of
60 to that in Y-SiO(2) but which lacks adjacent hydroxyl groups, and are 7 times more active than the ac
61 kenes, esters, ketones, acetals, unprotected hydroxyl groups, and phosphines) have been demonstrated
62 of (+)strand DNA with either a phosphate or hydroxyl group; and (iv) the 5' end of the DP-rcDNA (-)s
63 orm of carboxyfluorescein in which 3' and 6' hydroxyl groups are masked as acetate esters (CFDA).
66 of a fluorine atom adjacent to the phenolic hydroxyl group as in 3w, 3z, 3aa, and 3bb to strengthen
67 we identify the coverage of reactive surface hydroxyl groups as a suitable descriptor for the OER act
68 entified a method that enables protection of hydroxyl groups as benzyl, p-methoxybenzyl, or naphthyle
70 ium group is lower than that of the phenolic hydroxyl group, as is the case for the alpha-amino-prote
71 ing, or minimally the stereochemistry of the hydroxyl group at C-16, is crucial for the activity of P
72 lyzed oxidation can single out the secondary hydroxyl group at C3 in glucose, circumventing the more
73 aCaT keratinocytes, suggesting the lack of a hydroxyl group at C44 as a critical feature for PLTXs cy
74 lmitic acids, consisting of isomers with the hydroxyl group at different positions, were identified i
75 onium moiety appeared more proficient than a hydroxyl group at directing the stereochemical course of
76 4 belongs to the SDR family and oxidizes the hydroxyl group at position 17 of estradiol and 5-androst
78 efficiently coupled at -40 degrees C to the hydroxyl group at position 3 of glucopyranosyl acceptors
85 is a promising technique for the analysis of hydroxyl groups because of its unique characterization c
86 modulators BPAM97 (2) and BPAM344 (3) into a hydroxyl group (BPAM557 (4) and BPAM521 (5), respectivel
87 show that fucosyl residues do not migrate to hydroxyl groups but to acetamido moieties of N-acetylneu
88 ylation of acceptors with more than one free hydroxyl group by 2,3,5,6-tetrabenzoyl galactofuranosyl
89 ) derived by systematically exchanging every hydroxyl group by a fluorine atom, we developed a strate
90 ilitated by the coordination of the reactive hydroxyl group by Ca(2+) in the active site, lowering th
91 2) NPs promoted the concentration of surface hydroxyl groups ( C(-OH)) and the reactivity of AgFeO(2)
93 thered primary, secondary, and tertiary free hydroxyl groups can all react to give the corresponding
94 show that molecules containing at least two hydroxyl groups can be converted into methanol, which de
95 hat at least two framework Al(IV) sites with hydroxyl groups can exist in acidic zeolite catalysts in
97 xygenated hydrocarbons that bear one or more hydroxyl groups comprise a large set of natural and synt
100 ic acid feet, and "steps" along an isotactic hydroxyl-group-derivatized polyether track by the format
101 the MD simulation indicate that a ribose 2'-hydroxyl group destabilizes the pai-pai stacking of the
102 y the axial or equatorial orientation of two hydroxyl groups differentiating among these isomers in t
103 er aliphatics, free acid end-groups and free hydroxyl groups, differentiating between those derived f
104 During proton transfer to a basic support hydroxyl group, electron density is distributed through
108 acent Au sites was apt to react with surface hydroxyl groups formed from water splitting, leading to
109 -ray quality crystals of five compounds with hydroxyl groups forming five- and six-membered chelation
110 final phase involves removal of the tertiary hydroxyl group from pseudomonic acid B, PA-B, producing
113 ered azaenediyne, while the substrate with a hydroxyl group gave only traces of the desired 10-member
115 uch bicyclic compound carrying an equatorial hydroxyl group has activity equal to that of the parent
116 drophobic substituents are attached to the 6-hydroxyl groups, has been the subject of speculation.
118 lics was evaluated in model solutions, where hydroxyl groups, hydrophobic bonding and steric hindranc
119 talyzes regiospecific methylation at the C-7 hydroxyl group, (ii) TnmH exhibits broad substrate promi
120 nd tannin, (ii) the phosphitylation of their hydroxyl groups, (iii) NMR acquisition details, and (iv)
121 sing because of the directing influence of a hydroxyl group in C horizontal lineC bond hydrogenation.
122 refore, the selective conversion of a single hydroxyl group in natural products into a ketone would e
123 s efficiently prevented by deprotonating the hydroxyl group in position 2 of the glyconitriles during
124 tion of a persubstituted phosphole bearing a hydroxyl group in position 3 in 64% yield, and its oxida
125 tes are open enough to accommodate the extra hydroxyl group in RNA, further supporting our conclusion
126 hat this reaction proceeds with inversion of hydroxyl group in the anomeric center, which confirms in
127 nooxygenase, PtmU3, that installs a C-5 beta-hydroxyl group in the unified biosynthesis of platensimy
128 oscopy offers unique advantages in measuring hydroxyl groups in a single spectrum with high signal re
130 its for chemically mapping the importance of hydroxyl groups in carbohydrate-receptor interactions.
132 ive functionalization of seemingly identical hydroxyl groups in carbohydrates remains a long-standing
133 trolled subtle reactivity differences of the hydroxyl groups in carbohydrates were utilized to quickl
135 Our data demonstrate the existence of free hydroxyl groups in cutin and provide insight into how th
136 logs revealed the co-operative nature of the hydroxyl groups in mediating both this aqueous glycosyl
138 support the notion that the aminomethyl and hydroxyl groups in the capping group of Suprastat establ
140 le of the serine 364, and more precisely its hydroxyl group, in coupling sodium and substrate fluxes.
141 er, RdmB, it catalyzes the introduction of a hydroxyl group, in the case of NDUFAF5, into Arg-73 in t
142 RNase H2 to selectively create ligatable 3'-hydroxyl groups, in contrast to alternative methods that
144 vatives, depending on the positioning of the hydroxyl groups, induce various conformations of the est
146 by the tight-bonding of active centers with hydroxyl group intermediate, while the Mg atom coordinat
147 ) decreases their vapor pressure as a second hydroxyl group is incorporated to accelerate their oxida
149 -hydroxy-2-propyl)benzene, which has distant hydroxyl groups, is able to catalyze nucleophilic fluori
150 icting common sites of UGT conjugation, like hydroxyl groups, it can also accurately predict the gluc
151 thyris ADH1 catalyzes dehydrogenation of the hydroxyl groups, leading to the subsequent rearrangement
152 ded to the calcite surface through its polar hydroxyl group, leaving the hydrophobic ends of the etha
154 atalytic function is to lower the pKa of the hydroxyl group, making it a highly effective nucleophile
156 plication templates, while lagging strand 3'-hydroxyl groups may prime endonuclease-independent L1 re
157 bicyclic ring I carrying equatorial amino or hydroxyl groups mimicking the bound side chains of neomy
158 Dandante or amine NDamine, carboxyl NDvox or hydroxyl groups NDH and drop-casted or spray-coated onto
161 side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, whereas the unfavorable entropy mig
164 -triphosphate (2'-Az-dATP) onto the tyrosine hydroxyl group of a peptide, which is either tethered to
165 ron ion (Fea), which is proposed to bind the hydroxyl group of a postulated intermediate in the last
166 n ion (Fe(a)), which is proposed to bind the hydroxyl group of an intermediate in its reaction to fac
168 rase responsible for methylation of the meta-hydroxyl group of caffeoyl-coenzyme A (CoA) on the pathw
171 ons suggest that a hydrogen bond between the hydroxyl group of Hzp and a backbone amide carbonyl posi
172 olecular dynamic analysis indicated that the hydroxyl group of monophenolic substrates can bind to Cu
173 owth, characterized by acetylation of the C6 hydroxyl group of N-acetylmuramic acid in the PG glycan
174 , we firstly investigated how the additional hydroxyl group of NE could affect the properties of the
175 ation of a hydrogen bond from the side-chain hydroxyl group of Ser-497 to the hydroxyl group of 5, wh
176 covalent attachment of sugar moieties to the hydroxyl group of serine or threonine on proteins/peptid
177 tributed to a much stronger H-bond between a hydroxyl group of TETROL and the carbonyl group of the (
178 300(Sc), I2(I), is located near the bridging hydroxyl group of the [ScO4(OH)2] moiety [I2(I)...H-O =
179 vity for the glycosylation on the equatorial hydroxyl group of the acceptor was obtained thanks to th
180 Asp(A117) determines the orientation of the hydroxyl group of the acyl-CoA esters by H-bond formatio
181 nd between Trp222 of HA-HK68-MTA and the C-4 hydroxyl group of the alpha1-3-linked fucose of sLe(X),
182 e (k(1), rho = 0.65), and the pK(a)'s of the hydroxyl group of the carbinolamide (rho = 0.23) are rep
183 ned that PDI inhibition relied on the A ring hydroxyl group of the chalcone scaffold and cLogP increa
186 etween the oxygen of the directing group and hydroxyl group of the ligating acetic acid is crucial fo
187 core, stereocenters at C14 and C15, and the hydroxyl group of the m-tyrosine (m-Tyr) residue as key
188 transfer of the methyl group from SAM to one hydroxyl group of the myricetin in a cation-dependent ma
190 acidic residues, water molecules, and the 3'-hydroxyl group of the primer so that the A metal is in a
193 elA binds the CCA tail to orient the free 3' hydroxyl group of the terminal adenosine towards a beta-
194 e also establish that methylation of the C-3 hydroxyl group of the terminal alpha-l-Rha is achieved b
195 a methyltransferase that methylates the C-2 hydroxyl group of the terminal alpha-l-rhamnose (Rha) un
197 esis and by seeing close contact between the hydroxyl group of this residue and the azaribose moiety
200 tive site has an open structure and that the hydroxyl groups of all xylose residues in the active sit
201 ak reversible covalent bonds between vicinal hydroxyl groups of arabitol and boronic acid substituent
202 as been synthesized by connecting the tailed hydroxyl groups of C-propan-3-ol pyrogallol[4]arene with
203 erial cellulose nanopaper are reduced by the hydroxyl groups of cellulose nanofibers, acting as the r
204 ta, a benzyl etherification of nonesterified hydroxyl groups of glycerol and hydroxy fatty acids was
205 (2+) ions are bridged by the carboxylate and hydroxyl groups of lactate and the carboxylate group of
208 acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl groups of serine/threonine residues of cytosoli
209 hat catalyze the addition of GalNAc onto the hydroxyl groups of serines or threonines in protein subs
210 roteins within multicellular eukaryotes have hydroxyl groups of specific serine and threonine residue
214 that tetrahedral [Zn(NH3)4](2+) ions bind to hydroxyl groups of the film at a stoichiometric ratio of
215 c apolar pocket that surrounds the C4 and C5 hydroxyl groups of the natural substrate, cause the open
216 ep transesterification reaction where the 3' hydroxyl groups of the spacer target both repeat borders
219 uctures (particularly the number of terminal hydroxyl groups) of PS molecules to definitively identif
220 ed the differentiation between the secondary hydroxyl groups OH-3 and OH-5 of 1,2-cis or 1,2-trans d-
221 mportant to inhibit alpha-amylase, while the hydroxyl group (OH) at C3 of the C-ring was related to i
223 oordination of calcium by the two equatorial hydroxyl groups, OH3 and OH4, at the non-reducing end.
226 determine the effect of the position of the hydroxyl group on the antioxidant properties of flavonoi
228 As a result, the introduction of a meta hydroxyl group on the C4 anilino ring was computed to be
230 of ATP demonstrated the importance of the 2' hydroxyl group on the ribose ring in determining agonist
232 between amino acid side chains and phosphate/hydroxyl groups on PI(4,5)P(2) Binding of PI(4,5)P(2) al
233 photoelectron spectroscopy revealed that the hydroxyl groups on the GONR were removed by the reductiv
234 oscopy analysis confirms the presence of the hydroxyl groups on the INFGN surface, which acts as the
235 d (FTIR) spectroscopy suggested more surface hydroxyl groups on the NCC than the MCC particles and co
237 tify the favoured path, either through the 3-hydroxyl group or through the catecholic moiety in a ser
238 in a single aspect of the orientation of the hydroxyl groups or harbor subtle chemical modifications.
239 presence of specific chemical groups such as hydroxyl groups or hydrogens.The synthesis of two-dimens
242 c site and further demonstrates that the A76 hydroxyl groups participate in post-transfer editing onl
246 Additionally, other extra-lattice aluminum hydroxyl groups previously discussed in the literature b
247 ated by a second tetrahedral Al atom and its hydroxyl group protons in zeolite HZSM-5 is clearly reso
249 charides, deoxysugars, saccharides with free hydroxyl groups, pyranose, and furanose substrates.
251 emonstrate the importance of the location of hydroxyl groups relative to the hydrophobic face of the
253 this phenomenon, a lead compound FG03 with a hydroxyl group replacing the 3''-NH2 group of kanamycin
255 nformations in which hydrogen-bonding to the hydroxyl group results in direction of the epoxidation t
256 The data suggested that compounds having a p-hydroxyl group showed moderate 2,2-diphenyl-1-picrylhydr
258 PEG2000 was bound to adenosine on the 3',4' hydroxyl groups, stimulated cAMP increases and these inc
261 the derivatives of flavonoids, which have a hydroxyl group substituted at the R-3 position on the C
262 ross-linked polymer multilayers that present hydroxyl groups suitable for conventional phosphoramidit
263 Most notable is a trans-acting gamma/delta' hydroxyl group that 99% of other AAA+ proteins lack.
264 ng from the integrase active site the DNA 3'-hydroxyl group that is required for strand transfer acti
265 on that provides an array of surface-exposed hydroxyl groups that bind to polyQ peptides and may disr
266 , consists of negatively charged carboxyl or hydroxyl groups that limit attractive forces with the ce
268 ' effectiveness depends on the presence of a hydroxyl group, the chain length (four carbons), and the
269 n a manner that buries the cholesterol 3beta-hydroxyl group; they also bind tightly to NPC1 and NPC2
270 ocols and does not require the protection of hydroxyl groups, thus allowing the facile synthesis of a
271 hydrogen-bond networks, the contribution of hydroxyl groups to affinity can reach several orders of
272 ll electrophilic reagents that react with 2'-hydroxyl groups to interrogate RNA structure at single-n
274 cess involving nucleophilic addition of free hydroxyl groups to the carbamate linkages and exhibits a
275 ation reactions mainly involved oxidation of hydroxyl groups to the corresponding carboxylic acids.
276 ceptors through hydrogen bonding with B(OH)2 hydroxyl groups toward Cl(-), Br(-), HSO4(-), and AcO(-)
278 d stereoselective alkylation of carbohydrate hydroxyl groups via Rh(II)-catalyzed insertion of metal
279 Vitamin D3 metabolites lacking a 1alpha-hydroxyl group (vitamin D3, 25-hydroxyvitamin D3, and 24
282 differs from dopamine only for an additional hydroxyl group was not investigated at all in biosensing
289 l hydrophilic environments near the reactive hydroxyl group which stabilize both the proton and chlor
290 A-1(O2') starts attacking the phosphate as a hydroxyl group, which is hydrogen-bonded to deprotonated
291 e during interactions with water and surface hydroxyl groups, which can be used as fingerprints for t
292 ess copper, charge compensated by systematic hydroxyl groups, which leads to an open microporous fram
293 logous ester 27 allowed to introduce the C13 hydroxyl group with a high stereoselectivity in the hali
295 insertion step, which prefers insertion into hydroxyl groups with an adjacent axial substituent.
297 complete quantitative information about the hydroxyl groups with small amounts of sample (~30 mg) wi
298 ole-scavenging by surface water molecules or hydroxyl groups, with associated radical formation.
299 actions are possible when there are phenolic hydroxyl groups within substrates that contain a second