ライフサイエンスコーパス: hyper-

1 lative to the control at 51, 66, and 81 mM K(hyper).

2 tion diminishing with further increases in K(hyper).

3 l [isotonic (ISO)] or 3.0% NaCl [hypertonic (HYPER)].

4 t [TKO] and Human-Yeast Proteomics Resource [HYPER]).

5 g the OGTT was also significantly greater in HYPER (19,303 +/- 3939 ng/L.min) compared with the ISO t

6 seline (positive integer) was greater during HYPER (401.5 +/- 190.5 mmol/L.min) compared with the ISO

7 Here we propose HYPER, a group testing method based on hypergraph factor

8 onally limited pathogen followed by defense (hyper) activation during reproduction, reveals a subtle

9 an) ) and its reactivity to hypercapnia (CVR(HYPER) ) and hypocapnia (CVR(HYPO) ), respectively.

10 at 21 mM K(+) in all three groups (K(iso), K(hyper), and K(suc)).

11 smography to assess endothelium-dependent (% Hyper) and endothelium-independent vasodilatation (% Nit

12 hase, had no effect on the response of the K(hyper) and K(suc) groups at 21 mM but significantly enha

13 With the K(hyper) and K(suc) groups, the magnitude of the dilation

14 ng a new conformational grid search program, HYPER, and used together with longer-range constraints a

15 categorized into 7,537 differentially (46.6% hyper- and 53.4% hypo-) methylated regions.

16 rom strawberry exerted significantly greater hyper- and bathochromic spectral shifts than their acyla

17 or the first time that it caused paradoxical hyper- and biphasic phosphorylation.

18 arin; continued advances in the treatment of hyper- and dyslipidemias, new roles for beta-blockade in

19 oach identified 76 markers, of which 68 were hyper- and eight hypomethylated (LME, P < 0.05).

20 of 25 years of (annual and biannual) MDA in hyper- and holoendemic settings, with 65% and 80% therap

21 we provide evidence that genome-wide cancer hyper- and hypo- DNA methylation patterns are independen

22 ssible patterns of statistically significant hyper- and hypo- methylation in comparisons involving an

23 Hyper- and hypo-activation of the Integrated Stress Resp

24 ion is associated with pathological forms of hyper- and hypo-arousal that present in numerous neurops

25 , denatonium, detergents, heavy metals, both hyper- and hypo-osmotic shock and nose touch.

26 the disulfide-reducing agent dithiothreitol, hyper- and hypo-osmotic shock, amino acid starvation, ni

27 resulting in a shift in the balance between hyper- and hypo-phosphorylated 4E-BP1 and translational

28 yeast pro-prion protein Ure2p binds to both hyper- and hypo-phosphorylated Gln3p.

29 ctional supercoiling assays reveal that both hyper- and hypo-phosphorylated histones can be efficient

30 nent, KaiC, undergoes regular cycles between hyper- and hypo-phosphorylated states with a period of c

31 d in vivo using (2)H(2)O labeling in normal, hyper- and hypo-proliferative conditions.

32 Our findings unveil oscillations of hyper- and hypo-response to IFN-I in DS, predisposing in

33 reported a similar pattern of both increased hyper- and hypo-sensitivities across multiple senses.

34 about the neurofunctional manifestations of hyper- and hypo-somnia, and may explain inconsistent fin

35 me remodeling by human Swi-Snf is similar on hyper- and hypoacetylated MMTV arrays.

36 We find that both hyper- and hypoacetylation of individual lysines are ass

37 ees, with notable differences in patterns of hyper- and hypoactivation.

38 rventions and treatments appear to normalize hyper- and hypoactivations of brain regions involved wit

39 yeast complementation assay to measure both hyper- and hypoactive GCK variation, capturing 97% of al

40 Alternatively, hyper- and hypoactive states in males align selectively

41 s to be regulated by phosphorylation in both hyper- and hypoactive striatal DA neurons; in the latter

42 acterized by concentric rings of alternating hyper- and hypoautofluorescence, and foveal sparing of p

43 to 10 mM Ca(2+), allowing discrimination of hyper- and hypocalcemia.

44 PET,CO2 and CFV were computed separately for hyper- and hypocapnia during the LBNP and no-LBNP condit

45 0 mmHg, on cerebrovascular responsiveness to hyper- and hypocapnia in healthy humans.

46 overall cerebrovascular reactivity to CO(2) (hyper- and hypocapnia) was lower in patients with apnea

47 intenance of the cerebrovascular response to hyper- and hypocapnia.

48 e associated with dominant forms of familial hyper- and hypocholesterolemia.

49 IPS and the AG in MD, with patterns of both hyper- and hypoconnectivity.

50 2R partial agonists to simultaneously target hyper- and hypodopaminergia.

51 perechoic mass in 13 tumors and random mixed hyper- and hypoechogenicity with associated architectura

52 e is severely disrupted and characterized by hyper- and hypoediting of different genes, such as hyper

53 Hyper- and hypoenhanced regions were also smaller (eg, 2

54 In addition, for a series of hyper- and hypofusogenic F mutants, we quantified F-trig

55 Hyper- and hypofusogenicity can each be manifested throu

56 We demonstrate that hyper- and hypoglycaemia are common at the time of admis

57 Due to this variability, we believed that hyper- and hypoglycaemia would remain common in ICU care

58 Hyper- and hypoglycemia were associated with poor neurol

59 nt mechanisms: SGLT2 inhibitors prevent both hyper- and hypoglycemia, with expectedly little net effe

60 ith acute respiratory distress syndrome into hyper- and hypoinflammatory subphenotypes using plasma b

61 sed effects on central laboratory-determined hyper- and hypokalaemia (serum potassium 6.0 and <3.5 mm

62 effect of empagliflozin on the occurrence of hyper- and hypokalaemia in HF.

63 ogressive cerebellar ataxia with concomitant hyper- and hypokinetic movement disorders, severe early-

64 pring of immune-challenged mothers displayed hyper- and hypomethylated CpGs at numerous loci and at d

65 Individual hyper- and hypomethylated promoters allowed discriminati

66 terns identified unique patterns of aberrant hyper- and hypomethylation among epitypes, with variable

67 ings demonstrate a surprisingly high rate of hyper- and hypomethylation as a function of age in norma

68 Hyper- and hypomethylation at the IGF2-H19 imprinting co

69 monstrate that maternal asthma leads to both hyper- and hypomethylation in neonatal DCs, and that bot

70 type (50% decreased MTHFR activity) had both hyper- and hypomethylation in their sperm.

71 inct subgroup characterized by both aberrant hyper- and hypomethylation.

72 Thus, the response to both hyper- and hypoosmolar stimuli is impaired in trpv4-/- m

73 Furthermore, in response to hyper- and hypoosmotic shock, E. coli cells resumed thei

74 verify whether ictal perfusion changes, both hyper- and hypoperfusion, correspond to electrically con

75 ating, well-defined regions of portal venous hyper- and hypoperfusion; it likely has a multifactorial

76 progression; upregulated pRb displaying both hyper- and hypophosphorylated forms; increased levels of

77 The added recombinant CTD was quickly hyper- and hypophosphorylated in extract, became associa

78 We also provide evidence that both hyper- and hypophosphorylation inhibit SR protein splici

79 ALE across diagnoses and patterns of patient hyper- and hyporeactivity demonstrated abnormal activati

80 rmation required to interpret the changes in hyper- and hyporeflexive bands in pediatric spectral-dom

81 that genetic variations between FcgammaRIIA hyper- and hyporesponders regulate FcgammaRIIA-mediated

82 eterogeneity but did not distinguish between hyper- and hyposignal within an otherwise uniform activi

83 be inhibited with different selectivities by hyper- and hypotensive regions of the PAG.

84 ion was assessed by applying rapid pulses of hyper- and hypotensive stimuli to the neck via a customi

85 Benign thyroid disorders, especially hyper- and hypothyroidism, are the most prevalent endocr

86 r common clinical findings included muscular hyper- and hypotonia, spasticity, failure to thrive and

87 their linear bending elastic regime in both hyper- and hypotonic conditions.

88 s without CF, we investigated the effects of hyper- and hypotonicity on ion transport processes.

89 We then used this index to compare hyper- and hypovascular tumors, enabling the classificat

90 crystalline complex was consistent with the hyper- and hypsochromically shifted absorption spectra o

91 polar (DeltarcrR-NP) rcrR mutants, which are hyper- and nontransformable, respectively, to dissect th

92 tching of cultured endothelial cells between hyper- and normo-glycaemic conditions on bioenergetic an

93 Despite similarities in symptoms, hyper- and normosensitive patients with IBS differ in ce

94 Both the hyper- and suppressed-activity subtypes of MDD patients

95 The adenopathy at US was hyper- and/or isoechoic relative to the liver and thyroi

96 adenovirus associated double floxed inverted-HyPerRed, and demonstrated that KOR activation stimulate

97 lysis revealed an extensive influence of DNA hyper- as well as hypomethylation on miRNA regulation.

98 characterization are well-defined synthetic (hyper)-branched polymers.

99 catechin-3-gallate blocked expression of the hyper-, but not hypophosphorylated Bcl-X(L) in mitochond

100 (95% confidence interval = -35 to -26), CVR(HYPER) by 68% [interquartile range (IQR) = -94 to -44] a

101 At week 1, %S was depressed in HYPER, COMB, and HYPO (9+/-8%, 7+/-6%, and 5+/-4%, respe

102 ning (%S) was measured in regions displaying HYPER, COMB, or HYPO contrast patterns and in remote reg

103 o significant effect on dilations at lower K(hyper) concentrations but constricted the arteries relat

104 The estimated MGF were (hyper) disc-like, such that each neuron's firing modulat

105 aggregates from three hamster prion strains (Hyper, Drowsy, SSLOW) subjected to minimal manipulations

106 of sites by ignoring reads with excessive ('hyper') editing that do not easily align to the genome.

107 ign called high-yield-pileup-event-recovery (HYPER) electronics for processing the detector signal in

108 encing to study immune cell composition and (hyper-)expansion of circulating and joint-derived Tregs

109 ar mechanisms that control switching between hyper- (fresh water) and hypo-osmoregulation (seawater)

110 xcursion prediction, we propose a novel Hypo-Hyper (HH) loss function that penalizes errors based on

111 PrP(Sc) formation for the hyper (HY) and drowsy (DY) strains of the transmissible

112 amsters in the sciatic nerve with either the hyper (HY) or drowsy (DY) strain of the transmissible mi

113 (TME) agent prior to superinfection with the hyper (HY) strain of TME can completely block HY TME fro

114 erinfection with the short-incubation-period hyper (HY) strain of transmissible mink encephalopathy (

115 Binding of the hyper (HY) strain of transmissible mink encephalopathy (

116 in hamsters resulted in the selection of the hyper (HY) TME PrP(Sc) strain-dependent conformation and

117 rom the brains of hamsters infected with the hyper (HY), drowsy (DY), and 263K TSE strains yielded si

118 Specifically, the form (hyper, hypo or unchanged) and what role excitability dys

119 16.9 1.2, and 11.7 2.0 mm Hg h(-1) in groups Hyper, Hypo, Hypo-Baseline, and Hypo-ECCO(2)R, respectiv

120 The stages of hyper-, hypo-, and hyper-methylation patterns of the CDX

121 representation of these TFBS was observed in hyper-/hypo-methylated sequences where signi.cant change

122 These hyperadditive effects of CB hyper-/hypocapnia agree with previous findings using CB

123 iscovery of familial mutations implicated in hyper-/hypocholesterolemia by linkage studies and single

124 In four CB-denervated dogs, absence of hyper-/hypoventilatory responses to CB perfusion with PC

125 capnia agree with previous findings using CB hyper-/hypoxia.We propose that hyperaddition is the domi

126 on pediatric cancer, and high hyperdiploidy (HyperD) identifies the most common subtype of pediatric

127 endothelium plays a permissive role in the K(hyper)-induced response.

128 muscle perfusion maps categorized voxels as hyper-, iso-, or hypo-enhanced and were generated for th

129 Areas of cortical lobar hypo (hyper)-metabolism in the cerebrum that were 2 SDx from t

130 ized to 48 hours of hyperventilation (group "Hyper," n = 4); 48 hours of hypoventilation (group "Hypo

131 enous infusion of either 0.9% (ISO) or 3.0% (HYPER) NaCl saline, 12 subjects were passively heated un

132 Mice conditionally lacking UPF3A exhibit "hyper" NMD and display defects in embryogenesis and game

133 ined as COMB (first pass hypoenhancement) or HYPER (normal first pass signal enhancement).

134 a) a direct effect of the K(+)/osmolality (K(hyper)) on the endothelium or (b) a 'permissive' role of

135 d by hyperenhanced signal on delayed images (HYPER), or (3) both absence of normal first-pass enhance

136 tes with RNA polymerase II that has either a hyper- or a hypophosphorylated CTD.

137 ication during virion maturation by inducing hyper- or aberrant IN multimerization but are largely in

138 ntial abundance of 462 proteins and altered (hyper- or hypo-) acetylation of 436 lysine residues on 3

139 rin and GEFD1 variants cause a TRIO-mediated hyper- or hypo-activation of RAC1, respectively, and we

140 ate degree of tissue elongation, rather than hyper- or hypo-elongated organs.

141 he blood glucose level is essential to avoid hyper- or hypo-glycemic shocks associated with many meta

142 e precipitated by aggressive correction of a hyper- or hypo-osmolar state and until recently has been

143 the adverse effects, such as irritation and hyper- or hypo-pigmentation.

144 us research has not clarified whether neural hyper- or hypo-responsiveness to anticipated rewards pro

145 odels suggest that it could be caused by the hyper- or hypoaccumulation of phenylpropanoid intermedia

146 esults obtained with hypoacetylated MMTV and hyper- or hypoacetylated 5S rDNA arrays.

147 type with disrupted stress reactivity (i.e., hyper- or hypoactivation of the stress system), impaired

148 Finally, our data show that hyper- or hypoactivity of PP5 mutants increases Hsp90 bi

149 ions, gender, gestational age, pneumothorax, hyper- or hypocarbia, severity of illness, and cranial i

150 Naturally occurring mutations can lead to hyper- or hypocholesterolemia in human.

151 -blocking drug, in combination with either a hyper- or hypocholesterolemic diet, to show that elevate

152 ulation of its levels can cause either organ hyper- or hypoelongation.

153 oclonal antibody binding data indicated that hyper- or hypofusogenic mutations in the KKR motif affec

154 s, thus reducing the chances of experiencing hyper- or hypoglycaemia during exercise.

155 Sustained dysregulation of blood glucose (hyper- or hypoglycemia) associated with type 1 diabetes

156 None of the transplant recipients have had a hyper- or hypoglycemic episode since PIT and no complica

157 nal intensity average to identify regions of hyper- or hypointensity.

158 red between tissues, but similar clusters of hyper- or hypomethylated CpGs were observed, with hypome

159 ue genes were identified as overlapping with hyper- or hypomethylated regions, respectively.

160 ely determines which CGIs will be eventually hyper- or hypomethylated.

161 metabolic diseases may result in findings of hyper- or hypomobility, or carpal tunnel syndrome.

162 E613R allele of CD45 does not function as a hyper- or hypomorphic allele but rather alters the subst

163 rreflectivity over drusen, drusen cores, and hyper- or hyporeflectivity of drusen were also associate

164 lude irradiation, hyperbaric oxygen therapy, hyper- or hypothermic therapy, and photodynamic therapy.

165 He had no signs or symptoms of hyper- or hypothyroidism.

166 ents disrupting membrane properties, such as hyper- or hypotonic solutions, cholesterol removal and n

167 n semidominant mutation, which led to either hyper- or neofunctionalization of a redundant homoeologo

168 ng, low blood pressure, normal magnesium and hyper- or normocalciuria; they define a distinct subset

169 this response must be tightly regulated, as hyper- or suboptimal responses can be detrimental to the

170 thyroid disease (80.0% in hypo vs. 48.1% in hyper, P = 0.003).

171 n the heuristic selection of regularization (hyper-) parameters affecting the balance between overfit

172 phosphorylation level declined in hypo- and hyper- phosphatemia mouse models exhibiting skeletal def

173 During HYPER, plasma osmolality and copeptin increased (P < 0.0

174 GFP)-based fluorescent indicators roGFP2 and HyPer, respectively.

175 However, in HYPER, %S improved at week 7 from 9+/-8% to 18+/-5% (P<0

176 How hyper(-)sc emerges in the middle of a positively superco

177 olished neuropathic pain-induced mechanical (hyper-)sensitivity.

178 The essentially additive "hyper" shift due to lead chelation brought the Soret ban

179 The lead(II) chelate 19d gave an additional "hyper" shift that brought the Soret band to 604 nm.

180 transformation was also observed for strain Hyper, suggesting that this phenomenon was not limited t

181 ilament and cytoskeletal architecture induce hyper--SUMOylation of periplakin.

182 e damage (SNN plus infarction) was larger in hyper- than in normoglycemic animals at 2 and 4 h of rec

183 This "hyper" thermostable B-strap outperforms the previous gol

184 ysiologic significance of the shift from MTL hyper- to hypometabolism associated with IR.

185 e a testable framework for understanding how hyper- versus hypo-engagement of these networks may unde

186 We substantiated claims of hyper- versus hypofunctional GPi output in PD versus dys

187 bles and demonstrated that two-class models (hyper- vs hypoinflammatory subphenotypes) offered improv

188 ngly, when hamster-adapted strains (263K and Hyper) were subjected to dgPMCAb, their proteinase K dig

189 y decreases in Na(+), (2) hypertonic K(+) (K(hyper)) where K(+) was increased without a concomitant a

190 areas were identified using Z-scores of LGI (hyper: Z >= 2.58, hypo: Z <= - 2.58).