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1  H3 and H4 revealed that H4, but not H3, was hyperacetylated.
2 persensitive site forms, and the enhancer is hyperacetylated.
3  reporter is activated, its promoter becomes hyperacetylated.
4 in beta (C/EBPbeta) and c-Myc, which is also hyperacetylated.
5  the absence of HDAC3, the RORC promoter was hyperacetylated.
6  strain in which surface-associated EsxA was hyperacetylated.
7 sB isolated from the ackA or cobB mutant was hyperacetylated.
8 tor BRM is replaced by BRG1 and histones are hyperacetylated.
9 or to nucleosomes in which these domains are hyperacetylated.
10 mic, but inactive, to a stabilised, possibly hyperacetylated, active state.
11 on from a hypoacetylated "primed" state to a hyperacetylated-active state is incompletely understood.
12             Additional proximal domains were hyperacetylated after stimulation of transcription.
13 seven lysine residues in hsp90alpha that are hyperacetylated after treatment of eukaryotic cells with
14 indicate Vbeta and DbetaJbeta segments to be hyperacetylated and accessible in DN thymocytes.
15 enome is organized into histone H3 (K9, K14) hyperacetylated and hypoacetylated regions corresponding
16 t (LBH589), the extracellular hsp90alpha was hyperacetylated and it bound to MMP-2, which was associa
17 henomenon and found that Geminin maintains a hyperacetylated and open chromatin conformation at neura
18 ycle, an increase of comparable magnitude of hyperacetylated and phosphorylated histone H3 at Zp and
19 udies revealed that the polyQ-expanded AR is hyperacetylated and that pharmacologic reduction of acet
20          When chromatin templates were first hyperacetylated and then incubated with NURF, significan
21        In diabetic mice, CYP7A1 chromatin is hyperacetylated, and fasting to refeeding response is im
22 ed with chromatin, histone H4 became locally hyperacetylated, and gene expression was induced.
23                                              Hyperacetylated arrays show no change in the preference
24 ns were not induced, although histone H3 was hyperacetylated as measured by immunoblotting or by ChIP
25          However, the locus is not uniformly hyperacetylated, as there are regions of hypoacetylation
26 of other cell-cycle genes, which also become hyperacetylated at H3K18.
27        In Nonabokra, the upstream region was hyperacetylated at H3K9 and H3K27, and this acetylation
28 ated that during latency the LAT promoter is hyperacetylated at histone H3 (K9, K14) relative to lyti
29 reveal that the proximal insulin promoter is hyperacetylated at histone H3 only in beta cells.
30 E1 protein is hypophosphorylated at S336 and hyperacetylated at K337.
31     Actively transcribed genes are typically hyperacetylated at Lys residues of histones H3 and H4 an
32 HDA1 deletion, many Tup1-repressed genes are hyperacetylated at lysine 18 of histone H3, yet are not
33 hain acyl coenzyme A dehydrogenase (LCAD) is hyperacetylated at lysine 42 in the absence of SIRT3.
34 ith regions of chromatin containing histones hyperacetylated at lysine residues, a characteristic of
35 anscript (LAT) region of the viral genome is hyperacetylated at lysines 9 and 14 of histone 3 [H3(K9,
36  hypoacetylated on histone H3, whereas it is hyperacetylated at the plasma cell stage.
37                 Germline V(H) genes were not hyperacetylated at this stage, which accounts for D(H) t
38 sines on histone 3 at the Cad6b promoter are hyperacetylated before neural crest emigration, correlat
39 colocalize in discrete nuclear foci that are hyperacetylated but transcriptionally inactive.
40     Histones H3 and H4 simultaneously become hyperacetylated, but it remains unclear whether this is
41 ects of dSir2 with native histones that were hyperacetylated by treatment with acetic anhydride.
42  level of clutch-associated DNA decreased in hyperacetylated cells, especially in regions containing
43 A was associated with nucleosome clutches in hyperacetylated cells.
44 d Brd3 associate preferentially in vivo with hyperacetylated chromatin along the entire lengths of tr
45 scriptionally active macronucleus containing hyperacetylated chromatin and a transcriptionally silent
46 se activity, providing a direct link between hyperacetylated chromatin and transcriptional activation
47 ication that focuses on peak breadth, termed hyperacetylated chromatin domains (HCDs), which classifi
48 se (HAT) Esa1p or Gcn5p creates a segment of hyperacetylated chromatin that is at least 2.6 kb in siz
49 tylated chromatin, and in distributions from hyperacetylated chromatin, particularly for long repeat
50  the upstream locus control region reside in hyperacetylated chromatin.
51 disrupted ATRX binding to the centromeres of hyperacetylated chromosomes resulting in abnormal chromo
52 find that histones at the active origins are hyperacetylated, coincident with binding of the origin r
53         Mitochondria from SIRT3 KO mice were hyperacetylated compared to WT mice which may regulate k
54 active promoters, with H3 being dramatically hyperacetylated compared with that from inactive promote
55 he Trypanosoma brucei H2A C-terminal tail is hyperacetylated, containing up to five acetylated lysine
56 ers, however, resulted in the formation of a hyperacetylated domain over these genes in definitive er
57                                          The hyperacetylated domain was not seen in male cells or in
58 e erythroblasts reside within a single large hyperacetylated domain.
59 pothesize that formation of extended histone hyperacetylated domains across the Ifng gene region repr
60 ow the range of possible mechanisms by which hyperacetylated domains form.
61                                        These hyperacetylated domains occur exclusively at loci contai
62 on and active transcription, similar histone hyperacetylated domains were found in NK cells.
63            Previously, we characterized such hyperacetylated domains within mammalian beta-globin gen
64 term such patterns of histone modifications "hyperacetylated domains." Little is known of either the
65 tone H3 and H4 Lys residues are not globally hyperacetylated during phas expression.
66 ds and was absent from moderately condensed, hyperacetylated euchromatic bands and highly condensed,
67 and Hst4p, in which H3 K56 is constitutively hyperacetylated, exhibit hallmarks of spontaneous DNA da
68 relate with approximately 100 unprecedented, hyperacetylated expanses of chromatin that reach up to 2
69 g euchromatic genes, with active genes being hyperacetylated for H3 and H4 and hypermethylated at Lys
70 e via Eaf1, recognizes nucleosomes that have hyperacetylated H2A and H4 tails.
71 e-ChIP-seq revealed a striking enrichment of hyperacetylated H2A at Pol II transcription start region
72 gh Epl1, recognizes H3K4me3 nucleosomes with hyperacetylated H3 tails, while the TINTIN module, ancho
73 reases in H2A.Z levels in yeast mutants with hyperacetylated H3K56.
74 geting p300 on the presence of RNAPII, p300, hyperacetylated H4 and H3 and unmodified H4 and H3 in tr
75                                        While hyperacetylated H4 and H3 were found in the coding regio
76                                Antibodies to hyperacetylated H4 were used to immunoprecipitate dinucl
77                         Mle colocalizes with hyperacetylated H4Ac16 on the X-chromosome and some auto
78 s subsaturating levels with nonacetylated or hyperacetylated HeLa histones.
79 us subsaturated levels with nonacetylated or hyperacetylated HeLa histones.
80     These elements were also associated with hyperacetylated histone 3 in a lineage-specific manner a
81 ng was a COPD-specific eightfold increase of hyperacetylated histone H3.3.
82                                              Hyperacetylated histone H4 appeared within 2 h of the ad
83 aining peptides are comparable to those of a hyperacetylated histone H4-mimicking cognate peptide, an
84 s) that does not correlate directly with the hyperacetylated histone status.
85 ors such as trapoxin A (TPX), which leads to hyperacetylated histone, alters local chromatin architec
86                                    With this hyperacetylated histone-DNA complex, we observed potent
87                                   Domains of hyperacetylated histones and hypomethylated DNA extended
88 ponding reduction in the amounts of p300 and hyperacetylated histones associated with the transcribin
89 e H3 at lysine-4 (H3-meK4), colocalizes with hyperacetylated histones H3 and H4 in mammalian chromati
90 ) protocols to determine the distribution of hyperacetylated histones H3 and H4 in the Saccharomyces
91 ated at lysine 4 (H3-meK4) co-localizes with hyperacetylated histones H3 and H4 in transcriptionally
92 complex 2 protein (ORC2) and was enriched in hyperacetylated histones H3 and H4 relative to other reg
93 ted histones H3 and H4 more efficiently than hyperacetylated histones H3 and H4.
94 at alleviating BET protein interactions with hyperacetylated histones may aid in the prevention or tr
95              However, nucleosome assembly by hyperacetylated histones on interrupted CGG tracts was i
96                              Assembly of the hyperacetylated histones onto DNA yields a soluble histo
97 of Gcn5p-regulated genes are associated with hyperacetylated histones upon activation by low-copy Gcn
98        Interestingly, hypomethylated DNA and hyperacetylated histones were also located at the cyclin
99                                 We show that hyperacetylated histones were recruited to this site in
100  and repressively marked histones but not to hyperacetylated histones.
101 n in repressed conditions in the presence of hyperacetylated histones.
102 e DNA-bending protein HMG-1 or by the use of hyperacetylated histones.
103 yrate and trichostatin A were used to create hyperacetylated histones.
104 g around the nuclei of spermatids containing hyperacetylated histones.
105 histones are used, compared to assembly with hyperacetylated histones.
106 ed DNA and, importantly, was associated with hyperacetylated histones.
107 promoter is unmethylated and associated with hyperacetylated histones.
108 atients with ALD, there was disulfide-bonded hyperacetylated HMGB1, disulfide-bonded non-acetylated H
109 nction of hsp90, and targeting extracellular hyperacetylated hsp90alpha may undermine tumor invasion
110                                     SIRT3 is hyperacetylated in aged and obese mice, in which SIRT1 a
111                            Core histones are hyperacetylated in cells overproducing functional Gcn5p,
112 gions, and showed that H2A histones that are hyperacetylated in different combinations localised to d
113 t dominate the adult TCRdelta repertoire are hyperacetylated in DN thymocytes, independent of their p
114 he cyclin D1 promoter was hypomethylated and hyperacetylated in expressing cell lines and patient sam
115 at OPA1, a mitochondrial fusion protein, was hyperacetylated in hearts under pathological stress and
116  Hypersensitive site two of the LCR was also hyperacetylated in murine embryonic stem cells, whereas
117  shown that heart mitochondrial proteins are hyperacetylated in OVE26 mice, a transgenic model of typ
118   Here we show that this lysine is massively hyperacetylated in peripheral neutrophils.
119 iate domain and the 3' V(H) genes, which are hyperacetylated in response to DJ(H) recombination.
120 )-dependent reversible acetyl-lysine that is hyperacetylated in Sirt3/ livers at 3 months of age.
121 rectly binds to the P2rx7 enhancer, which is hyperacetylated in the absence of HDAC3.
122 t that histone H3 and H4 were constitutively hyperacetylated in the donor Smu region before and after
123           Furthermore, CerS1, -2, and -6 are hyperacetylated in the mitochondria of SIRT3-null mice,
124  and both active and inactive promoters were hyperacetylated in yolk sac.
125                           Moreover, c-Myc is hyperacetylated, levels of p27 are reduced, and cyclin-d
126 erfusion biopsies contained macrophages with hyperacetylated, lysosomal disulfide-HMGB1 that increase
127 ealed the formation of ZNF532-NUT-associated hyperacetylated megadomains, distinctly localized but ot
128 leading to disruption of BRD4-NUT binding to hyperacetylated megadomains.
129                                        These hyperacetylated "megadomains" are formed by the BRD4-NUT
130 ons via Hi-C and super-resolution imaging of hyperacetylated melanoma cells and identified differenti
131                                 By contrast, hyperacetylated mitotic chromosomes lack a defined surfa
132 sulted in increased DNase I accessibility on hyperacetylated mononucleosomes and substantial reductio
133 n enrichment of ASD genetic risk variants in hyperacetylated noncoding regulatory regions linked to n
134 BRD4 is believed to lead to the formation of hyperacetylated nuclear foci, as seen by immunofluoresce
135                                              Hyperacetylated nucleosomal arrays show only subtle diff
136   The distinct H3K4me3 chromatin profile and hyperacetylated nucleosomes at transcription start sites
137                                      We find hyperacetylated nucleosomes less susceptible to CoREST/L
138 t it is thermodynamically more difficult for hyperacetylated nucleosomes to assemble onto the 172-12
139 o a more natural system involving intact but hyperacetylated nucleosomes.
140 ed identical cleavage patterns in normal and hyperacetylated nucleosomes.
141                                    Nav1.5 is hyperacetylated on K1479 in the hearts of patients with
142 erform assays with arrays reconstituted with hyperacetylated or trypsinized histones and isolated his
143 matin immunoprecipitation with antibodies to hyperacetylated or unacetylated H4 or H3.
144 al arrays reconstituted with hypoacetylated, hyperacetylated, or partially trypsinized histones.
145               Pull-down assays revealed that hyperacetylated p300 HAT is more efficiently retained by
146 300 HAT acetylation of a histone H4 peptide, hyperacetylated p300 HAT is much more potently inhibited
147 utoacetylation was retained about as well as hyperacetylated p300 HAT, suggesting that the loop and A
148 the cytosol, autophagy is abrogated, ATG7 is hyperacetylated, p53 acetylation is abolished, and p300
149 athways but encoding normal small T showed a hyperacetylated pattern similar to that of wild-type vir
150 nally, deletion of alpha-helix 30 results in hyperacetylated PG, suggesting this LtgA variant affects
151                     Of note, the top 38 case hyperacetylated promoters (P < 0.05) included >15 genes
152                   Here, we uncover a list of hyperacetylated proteins in the context of acutely reduc
153 terochromatic domains in vivo, histone H3 is hyperacetylated, providing evidence that the chromatin a
154 anied by enhanced chromatin accessibility at hyperacetylated regions in the gene body.
155 (HDACs) revealed hundreds of genes linked to hyperacetylated regions targeted by CBP.
156  region containing the 5' exon of KOS/29 was hyperacetylated relative to lytic gene regions in the ab
157 on of SIRT1 in macrophages renders NF-kappaB hyperacetylated, resulting in increased transcriptional
158  Smarce1 as well as in the reorganization of hyperacetylated round spermatid chromatin.
159 erved an increased frequency of mutations in hyperacetylated Sgamma DNA segments immunoprecipitated w
160                                          The hyperacetylated species concentrates at the 5' end of ac
161 plays a detrimental role when cells are in a hyperacetylated state and experience treatment with radi
162               We find that acetate induces a hyperacetylated state of histone H3 in hypoxic cells.
163 overexpressed a point mutant that mimics the hyperacetylated state of Hsp90 at lysine K294.
164       Selected mutations in CREBBP lead to a hyperacetylated state that increases CBP and BRCA1 acety
165             We found that inducing a histone hyperacetylated state via HDAC inhibition transforms a l
166 nitially, a 120 kb domain of germline DNA is hyperacetylated, that extends from D(FL16.1), the 5'-mos
167 a result, histones at the cat-3 locus become hyperacetylated to promote its transcription.
168 criptionally inactive state but not with the hyperacetylated transcriptionally active form.
169 promoter-associated histones are transiently hyperacetylated, while those in the coding region are no
170 cle oocyte and zygote chromatin are globally hyperacetylated, with noncanonical, broad H3K27ac domain
171 r normal locations, and that histones became hyperacetylated within these regulatory elements.
172 lization when heterochromatic regions become hyperacetylated without HDAC activity.
173 s complemented with XPA-K6367Q, which mimics hyperacetylated XPA, display significantly higher UV sen

 
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