1 ) mice display hyperactive B-1 cells and IgM hyperglobulinemia.

2 ing cells, with older mice switching to IgG1 hyperglobulinemia and autoantibody development.

3    Myo18A-deficient mice displayed serum IgM hyperglobulinemia and increased splenic IgM-secreting ce

4 y of marginal zone B cells, hyperplasia, and hyperglobulinemia, indicating that the KSHV latency locu

5 cells were chronically activated, leading to hyperglobulinemia triggered by increased plasma cell fre