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1 utagenesis and that this subpopulation(s) is hypermutable.
2 nditions that predispose to PNH PIG-A may be hypermutable.
3 OBEC3 damaged, escape extrusion, and acquire hypermutable advantage.
4                         Somatic WS cells are hypermutable and have elongated S phases, suggesting pos
5 ample set, suggesting that these markers are hypermutable and should prove valuable for the discrimin
6 ion mutants are sensitive to UV irradiation, hypermutable, and hyper-rec.
7                       We suggest that FAA is hypermutable, and that slipped-strand mispairing, a muta
8                          We propose 23 genes hypermutable at loss-of-function (LoF) sites as candidat
9 pressor TP53 (coding for the protein p53) is hypermutable at some stage of carcinogenesis, the freque
10     The published data indicate that TP53 is hypermutable at some stage of tumor development.
11  is suggested that at immunoglobulin loci in hypermutable B cells, mismatched base pairs are "correct
12                           The correlation of hypermutable base frequencies with -DeltaG values is poo
13 DNA folding analysis indicates that the most hypermutable bases in exons 5, 7, and 8 of the p53 tumor
14 pression of the FMR1 gene, which carries the hypermutable CGG repeat in the 5' untranslated portion o
15                                              Hypermutable colorectal and endometrial tumors with func
16 s insufficient to differentiate cells into a hypermutable condition.
17 s per kilobase (kb), and only 3.7% of the 30 hypermutable CpG dinucleotide pairs in the consensus rem
18 2.4% from the consensus, retained 54% of its hypermutable CpG pairs, and which has a full-length tran
19 e assay to identifying genetic variations in hypermutable CpG regions across human chromosome 21.
20 y observed missense enrichment; overlap with hypermutable CpG sites accounts for the recurrent missen
21 the strength of gBGC does not differ between hypermutable CpG sites and non-CpG sites, suggesting tha
22 nitely associated with presumably methylated hypermutable CpG sites, and in a typical GC-asymmetric g
23 annot be caused by biased gene conversion or hypermutable CpG sites.
24 pected, the younger orthologs contained more hypermutable CpGs than the older ones because of their c
25                      We found MIBC cells are hypermutable, deficient in DNA repair and have markedly
26 rom 17 patients, we used somatic variants in hypermutable DNA regions to reconstruct high-confidence
27 ature of Ig hypermutation is the presence of hypermutable DNA sequences that are preferentially found
28               The repair defect of the three hypermutable, drug-resistant cell lines is only evident
29 results suggest that the genus Oenococcus is hypermutable due to the loss of mutS and mutL, which occ
30                Therefore, IESs are volatile, hypermutable elements that are inserted, removed, shifte
31  cancer predisposition in which cells become hypermutable, exhibit high frequency of sister chromatid
32        Both rad28 and rad26 null mutants are hypermutable following exposure to UV light.
33 a with elevated mutability that often remain hypermutable for the duration of selection.
34 g defective cells there exists a transiently hypermutable fraction that would be inviable if cells we
35 was significantly decreased targeting of the hypermutable G in RGYW motifs.
36 GTPase family that was first identified as a hypermutable gene in human B lineage lymphomas.
37                       Intriguingly, the four hypermutable genes are susceptible to chromosomal transl
38 iking contrast, all mutations arising in the hypermutable GFP+/- strains were small (1- to 2-base) ch
39 families with BHD and therefore represents a hypermutable "hotspot" for mutation in BHD.
40 as been suggested that the PIG-A gene may be hypermutable in PNH.
41             Here we have mapped mutations in hypermutable intergenic and intronic polyguanine tracts
42 enomes possess minisatellite-like sequences, hypermutable loci have not been identified that suggest
43 her bottlenecks have driven the evolution of hypermutable loci.
44                           A diverse range of hypermutable mechanisms have evolved in infectious agent
45                              These localised hypermutable mechanisms include multi-gene phase variati
46                    An extra 17 genes feature hypermutable missense mutations at individual positions,
47 instability modulates DNA repair by toggling hypermutable mononucleotide homopolymer runs in MSH6 and
48  activated T cells (NFAT) binding sites, and hypermutable motifs in POLE-mutant and other cancers.
49            While neoantigens result from the hypermutable nature of dMMR, it is unknown how dMMR acti
50                                        RS is hypermutable over the total 625 nucleotides of the varia
51        Microsatellite instability (MSI) is a hypermutable phenotype caused by the loss of DNA mismatc
52       However, in many cases, despite that a hypermutable phenotype is detected in a patient, no muta
53  partial DarG(Mtb) -depletion and leads to a hypermutable phenotype.
54 LE, MLH1, and MSH6 and the tumor cells had a hypermutable phenotype.
55  results in microsatellite instability and a hypermutable phenotype.
56 sed assay interrogating somatic variation in hypermutable polyguanine (poly-G) repeats can provide a
57  hypothesize that these deletions occur in a hypermutable region because of surrounding repetitive se
58 s were identified in the previously reported hypermutable region of BCL6 in all three tumors.
59 coded protein, this mutation creates a small hypermutable region of the gene, indirectly causing canc
60 satellites in the hMSH3 and hMSH6 genes, and hypermutable regions of p53 were unaffected.
61 eno-associated virus genome processing and a hypermutable repeat sequence-dependent reporter.
62                    Recently, we have shown a hypermutable response to the food-associated heterocycli
63 combination rate and an increased density of hypermutable sequence contexts.
64 gs invoke the notion of "unmasking" specific hypermutable sequences in particular genes adding furthe
65                           Phase variation of hypermutable simple sequence repeats (SSRs) is a widespr
66 tune gene networks in Escherichia coli using hypermutable simple sequence repeats embedded in the spa
67 phase-variable switches in expression due to hypermutable simple-sequence repeats.
68 E. coli deficient in mismatch repair unmasks hypermutable sites in certain genes or intergenic region
69  On average, only 20% of the 73 surmised CpG hypermutable sites in the consensus remain.
70 c regulatory alteration that makes the cells hypermutable so that when the cell population inheriting
71 vealed that cancer tolerance to formation of hypermutable ssDNA is similar to yeast and that the pred
72 sis in a subpopulation of starved cells (the hypermutable state model).
73 the mutation rate in response to stress (the hypermutable state model, HSM).
74 0(5) cells (the number proposed to enter the hypermutable state).
75 ion and real-time visualization of transient hypermutable states in situ.
76                                          The hypermutable status of the genus Oenococcus explains the
77                Of nine independently derived hypermutable strains, seven contained a defective mutS a
78 ty by the adaptive response creates a viable hypermutable subpopulation of cells that acts as a sourc
79                      The existence of such a hypermutable subpopulation(s) raises important considera
80 phenotype would render MMR-deficient animals hypermutable to IR, we compared IR mutagenesis of Pms2-d