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1 over which life exists (from psychrophile to hyperthermophile).
2 s C (psychrophiles) and up to 122 degrees C (hyperthermophiles).
3 aculum aerophilum, and Aquifex aeolicus (all hyperthermophiles).
4 m Aquifex aeolicus, an ancient Gram-negative hyperthermophile.
5 ritical for the future studies of this model hyperthermophile.
6 rt of a thermostable glucostat from a marine hyperthermophile.
7 f DNA microarrays to either an archaeon or a hyperthermophile.
8 first for a transcriptional regulator from a hyperthermophile.
9 emonstrate the activity of acetate-degrading hyperthermophiles.
10 across species ranging from psychrophiles to hyperthermophiles.
11  applies at temperatures more appropriate to hyperthermophiles.
12 fe are primarily anaerobic, sulphur-reducing hyperthermophiles.
13  and 24 to 31 known to occur in the archaeal hyperthermophiles.
14 e absence of dihydrouridine from the tRNA of hyperthermophiles.
15 mble those of the other oxidoreductases from hyperthermophiles.
16  which is comparable to the doubling time of hyperthermophiles.
17 anol via acetaldehyde as the intermediate in hyperthermophiles.
18 erentially present in archaeal and bacterial hyperthermophiles.
19  source of frequent spontaneous mutation for hyperthermophiles.
20 difications previously reported for archaeal hyperthermophiles.
21 , the RNA world, and organisms preceding the hyperthermophiles.
22 -1,1'-phosphate (DIP), an osmolyte unique to hyperthermophiles.
23 fications are rare in mesophiles, in extreme hyperthermophiles, ~50% of modifications are dynamic.
24  noncovalent hexamer of DHO and ATC from the hyperthermophile A. aeolicus at 2.3 A resolution.
25 e Archaea: ApPgb from the obligately aerobic hyperthermophile Aeropyrum pernix, and MaPgb from the st
26 ost thermostable viruses known; it infects a hyperthermophile Aeropyrum pernix, which grows optimally
27 ridine is absent from the tRNA of almost all hyperthermophiles and most Archaea but is ubiquitous in
28  ATP-utilizing enzymes to be purified from a hyperthermophile, and ACS II is the first enzyme of the
29 n all organisms except certain parasites and hyperthermophiles, and this pattern of occurrence closel
30 g inhibitor of the LpxC deacetylase from the hyperthermophile Aquifex aeolicus, and it has excellent
31 ain of BCCP (BCCP Delta 67) from the extreme hyperthermophile Aquifex aeolicus.
32 d, overexpressed, and purified LpxC from the hyperthermophile Aquifex aeolicus.
33                         The amt genes of the hyperthermophiles Aquifex aeolicus and Methanococcus jan
34                            The genome of the hyperthermophile Archaeoglobus fulgidus encodes a putati
35 e P protein aRpp29 from the sulfate-reducing hyperthermophile Archaeoglobus fulgidus was determined a
36                            The genome of the hyperthermophile archaeon Pyrococcus furiosus encodes tw
37 e presence of salt while the thermophile and hyperthermophile are destabilized.
38 en proposed, largely for the reason that the hyperthermophiles are claimed to be the last common ance
39 e stability curves for the histones from the hyperthermophiles are displaced vertically to higher ene
40                     Glycosyl hydrolases from hyperthermophiles are, thus far, the most widely studied
41 lication is therefore extremely important in hyperthermophiles as the rate of oxidative damage to DNA
42     One report on this enzyme, R.PabI from a hyperthermophile, ascribed the breakage to high temperat
43 dration effects preferentially stabilise the hyperthermophiles at high temperatures.
44 n homologue from Methanococcus jannaschii, a hyperthermophile, at 1.6 A resolution.
45 A repair in archaea have been conducted with hyperthermophiles because of the additional stress impos
46                                   Sac7d is a hyperthermophile chromatin protein which binds non-speci
47 eculiar physiology, ecology and phylogeny of hyperthermophiles combine to suggest that these prokaryo
48 discussed in regards to the common idea that hyperthermophile enzymes are nearly inactive at low temp
49 temperature than is secondary structure, yet hyperthermophiles exhibit only modest levels of spontane
50                  Specifically, early-evolved hyperthermophiles express high levels of high-affinity c
51 ation of an aerobic polysaccharide-degrading hyperthermophile, Fervidibacter sacchari, previously asc
52 nd physiologically to six similarly enriched hyperthermophiles from samples associated with seafloor
53  other deep subsurface bacteria and cultured hyperthermophiles from the Thermotogae phylum.
54 utative genes in the spindle-shaped archaeal hyperthermophile fuselloviruses have no sequences that a
55                 Aquifex aeolicus, an extreme hyperthermophile, has neither a full-length carbamoyl-ph
56 n direct physical contact with its host, the hyperthermophile Ignicoccus hospitalis.
57                                          The hyperthermophiles include both bacteria and archaea, alt
58         Newly described adaptive features of hyperthermophiles include proteins stable to 200 degrees
59             Higher thermal stability for the hyperthermophile is obtained even if the mesophile is mo
60 proteins, it is found that in each case, the hyperthermophile is predicted to remain stable to a temp
61                                        Early hyperthermophile life, probably near hydrothermal system
62 mophile M. thermolithotrophicus (Mt) and the hyperthermophiles M. jannaschii (Mj) and M. igneus (Mi).
63 rothermal vent environments have yielded new hyperthermophiles (maximal growth at 90 degreesC or grea
64                                              Hyperthermophiles may appear at the base of some phyloge
65               Study of homologs in bacterial hyperthermophiles may shed light on both mechanisms of a
66 ronment of P. aerophilum, and possibly other hyperthermophiles, may be compatible with protein disulf
67 ly of the 12-subunit RNA polymerase from the hyperthermophile Methanocaldococcus jannaschii, we descr
68 ound in separate but homologous enzymes, the hyperthermophile Methanococcus jannaschii has an enzyme,
69  used to analyse the genomic sequence of the hyperthermophile Methanococcus jannaschii, addressing qu
70 of a DEAD box putative RNA helicase from the hyperthermophile Methanococcus jannaschii.
71 ting nucleotidase was characterized from the hyperthermophile Methanococcus jannaschii.
72 hile Methanococcus thermolithotrophicus, and hyperthermophiles Methanococcus jannaschii and Methanoco
73 tructure of one such protein, MJ0577, from a hyperthermophile, Methanococcus jannaschii, at 1.7-A res
74 en HMfB and HFoB, archaeal histones from the hyperthermophile Methanothermus fervidus and the mesophi
75 ly 78% sequence homology with rHMfB from the hyperthermophile Methanothermus fervidus, and the result
76 cicum, and rHMfA, rHMfB, and rHPyA1 from the hyperthermophiles Methanothermus fervidus and Pyrococcus
77                                          The hyperthermophile Nanoarchaeum equitans is an obligate sy
78 ticular genes were thermophiles, and neither hyperthermophiles nor mesophiles.
79 -genome DNA microarray was constructed for a hyperthermophile or a nonhalophilic archaeon by using th
80 hrin is the first to be characterized from a hyperthermophile or from an archaeon, and the results ar
81         The archaeon TBP, from the halophile/hyperthermophile organism Pyrococcus woesei, is adapted
82                                         Only hyperthermophiles (organisms optimally living in water a
83                        Stabilization of this hyperthermophile protein and its DNA complex by a surfac
84 f potential ion pairs on the surface of this hyperthermophile protein do not result in an inordinate
85 ilizing factor that distinguishes the native hyperthermophile protein from small mesophile proteins.
86 his measure of fluidity for the mesophile vs hyperthermophile protein interiors.
87                  As shown previously for the hyperthermophile protein, nearly all backbone amides of
88 underlying conformational equilibrium in the hyperthermophile protein.
89  pH-dependence of protein stability in these hyperthermophile proteins is due to independent titratio
90 underlies the increased thermal stability of hyperthermophile proteins is not supported by these data
91 acking on the structure and stability of the hyperthermophile proteins Sac7d and Sso7d have been stud
92              Sac7d and Sso7d are homologous, hyperthermophile proteins with a high density of charged
93 mon expectation of increased rigidity in the hyperthermophile proteins, below room temperature Pf rub
94 e the importance of ion pairs in stabilizing hyperthermophile proteins.
95 relate with optimal growth temperature among hyperthermophiles provides indirect evidence that other
96 ational dynamics of the rubredoxins from the hyperthermophile Pyrococcus furiosus (Pf) and the mesoph
97 drogen bond networks in rubredoxins from the hyperthermophile Pyrococcus furiosus (PfRd), and its mes
98 e unfolding kinetics of rubredoxins from the hyperthermophile Pyrococcus furiosus (RdPf) and the meso
99 mination of glutamate dehydrogenase from the hyperthermophile Pyrococcus furiosus and the comparison
100                             The fermentative hyperthermophile Pyrococcus furiosus contains an NADPH-u
101              We have recently shown that the hyperthermophile Pyrococcus furiosus has an extraordinar
102                          Rubredoxin from the hyperthermophile Pyrococcus furiosus is the most thermos
103 ssion, we expressed a gene from the archaeal hyperthermophile Pyrococcus furiosus that reduces O(2)(-
104 The small heat shock protein (sHSP) from the hyperthermophile Pyrococcus furiosus was specifically in
105                   PF0610, a protein from the hyperthermophile Pyrococcus furiosus, has homologues onl
106                 First characterized from the hyperthermophile Pyrococcus furiosus, it is unique to th
107 tion, and has been compared to that from the hyperthermophile Pyrococcus furiosus.
108  Methanothermus fervidus; and hPyA1 from the hyperthermophile Pyrococcus strain GB-3a.
109  IIB homolog, and a DNA target, all from the hyperthermophile Pyrococcus woesei.
110  hexameric glutamate dehydrogenases from the hyperthermophiles Pyrococcus furiosus and Thermococcus l
111  disulfides in the sulfur-reducing anaerobic hyperthermophiles Pyrococcus horikoshii and Pyrococcus f
112 ulfolobus solfataricus P2), and an anaerobic hyperthermophile (Pyrococcus furiosus DSM 3638).
113                            Herein, the model hyperthermophile, Pyrococcus furiosus, which grows optim
114 tein that is both specific and common to all hyperthermophiles, reduces the rate of double-stranded D
115 ation sensitivity studies also indicate that hyperthermophiles repair their DNA efficiently in vivo,
116 cular NMR hydrogen bond pattern found in the hyperthermophile rubredoxin leads to an increased stabil
117 of DNA at the optimal growth temperatures of hyperthermophiles seem incongruent with the requirements
118                       For example, bacterial hyperthermophiles seem to have exchanged genes with arch
119 rison of the physiology of the two groups of hyperthermophiles; some potential differences between th
120                          Reverse gyrase is a hyperthermophile-specific enzyme that can positively sup
121 rison, unfractionated tRNA from the archaeal hyperthermophile Stetteria hydrogenophila cultured at 93
122 of the folding of recombinant Sac7d from the hyperthermophile Sulfolobus acidocaldarius is mapped usi
123        Sac7d is a chromatin protein from the hyperthermophile Sulfolobus acidocaldarius that severely
124  Sac7d is a small chromatin protein from the hyperthermophile Sulfolobus acidocaldarius which kinks d
125 lished for 16S and 23S rRNAs of the archaeal hyperthermophile Sulfolobus solfactaricus by using combi
126 of a number of DNA-binding proteins from the hyperthermophile Sulfolobus solfataricus that has been a
127 In comparison with the AS structure from the hyperthermophile Sulfolobus solfataricus, the S. marcesc
128 f chemoreceptors from Thermotoga maritima, a hyperthermophile that has served as a useful source of c
129              Furthermore, our discovery that hyperthermophiles that had previously been thought to re
130 ummary, TK0353 is a novel AP lyase unique to hyperthermophiles that provides redundant repair activit
131 100 degreesC, the growth temperatures of the hyperthermophiles, the half-lives are too short to allow
132              Here, we map m(5)C in the model hyperthermophile, Thermococcus kodakarensis.
133 atalyzed by dihydrofolate reductase from the hyperthermophile Thermotoga maritima (TmDHFR) are presen
134 atalyzed by dihydrofolate reductase from the hyperthermophile Thermotoga maritima (TmDHFR) has been e
135 nt composition on catalysis by DHFR from the hyperthermophile Thermotoga maritima.
136 fine the interaction of P1 and P3P4 from the hyperthermophile Thermotoga maritima.
137 rium NRC-1) and some bacteria, including the hyperthermophiles Thermotoga maritima and Aquifex aeolic
138                        Co-cultivation of the hyperthermophiles Thermotoga maritima and Methanococcus
139           Soj and Spo0J of the Gram-negative hyperthermophile Thermus thermophilus belong to the cons
140 ynthesis of enzymes and other biopolymers in hyperthermophiles thriving in these ecosystems.
141 r emulated intracellular conditions found in hyperthermophiles, thus protecting DNA from rapid thermo
142 tion of a dehydrogenase from this Sulfolobus hyperthermophile to asymmetric synthesis and the first e
143  topological relaxation being performed by a hyperthermophile topoisomerase.
144 ,2'-O-trimethylguanosine, were found only in hyperthermophile tRNA, consistent with their proposed ro
145  from mesophiles, moderate thermophiles, and hyperthermophiles was examined.
146          The protein appears to be unique to hyperthermophiles, where its activity is believed to pro
147 ngoing release of genomic sequence data from hyperthermophiles will continue to accelerate the discov
148 it is not possible to quantitatively compare hyperthermophiles with mesophiles by the rRNA method.
149                               We report that hyperthermophiles within the Aquificota (Thermocrinis),

 
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