ライフサイエンスコーパス: hypervalent

1 erve as activators for transmetalation via a hypervalent 10-Si-5 siliconate intermediate.

2 formulation, which instead assigned it as a hypervalent 19-electron hydride, [Fe(III)(eta(5)-Cp*)(dp

3 n which the radicals are linked laterally by hypervalent 4-center 6-electron S...S-S...S sigma-bonds.

4 Irradiation in the solid state of the hypervalent 4c-6e S...S-S...S bridged sigma-dimer of a b

5 Halogenoalkynes, hypervalent alkynyliodoniums, acetylene sulfones and in

6 On the basis of hypervalent alpha-aryliodonio diazo triflate salts 1A, 2

7 Hypervalent ammonium radicals produced by electron captu

8 achieved by functionalizing the periphery of hypervalent and highly electron-deficient phosphorus(V)

9 Palladium-catalyzed cross-coupling of hypervalent arylsiloxane derivatives proceeded in good t

10 d to the outcome described here of a central hypervalent atom bound on one face by a small cyclic car

11 derivatives, thus breaking the sulfur-sulfur hypervalent bond that is always found in this kind of co

12 In hypervalent bonding (HVB), secondary bonding (SB) and hy

13 Hypervalent bonding ensues.

14 The combination of strain and hypervalent bonding, and the way they work in concert to

15 by analogy with three-orbital four-electron "hypervalent" bonding picture in such molecules as I(3)(-

16 ition to the recently reported reactivity of hypervalent bromines as aryne precursors, the first tran

17 ergent synthesis using the dual character of hypervalent bromines.

18 Recent discovery of hypervalent catalytic systems and recyclable reagents, a

19 Hypervalent chloranes are a class of rare and poorly exp

20 )(-) system; (iii) the formation of a Fe(IV) hypervalent compound may be essential for heme(Fe)-catal

21 eight-electron configuration in [1](+) to a hypervalent configuration in 2.

22 ol of ethyl acetoacetate was developed using hypervalent diaryliodonium salts under mild and metal-fr

23 h tripnictides, the ability to accommodate a hypervalent electron count is the largest in the middle

24 Herein, we present a hypervalent F-iodane mediated umpolung of pyridyl ketone

25 Hypervalent Fe(V) =O species are implicated in a multitu

26 stable thioperoxide form (O-SCF(3)), and the hypervalent form (I-SCF(3)) has been elusive.

27 )Cl(3)(o-dppp)(2) (2), a complex combining a hypervalent four-coordinate tellurium atom and an octahe

28 ormation of the fluorophenylgermanes and the hypervalent germanate species as possible intermediates.

29 bitors, despite their efficiency at reducing hypervalent haem iron.

30 apparent rate constants for the reduction of hypervalent haem pigment ferrylmyoglobin (MbFe(IV)O) by

31 ples for a new family of structures with two hypervalent halogens in the ring.

32 Hypervalent halonium salts are versatile arylating agent

33 The term "hypervalent" has been suggested for derivatives of main-

34 ity of stable nitroxide radicals to detoxify hypervalent heme proteins such as ferrylmyoglobin (MbFeI

35 2 evolution and providing protection against hypervalent heme proteins.

36 he significantly higher thermal stability of hypervalent heterocycles compared to their acyclic analo

37 This review is focused on hypervalent heterocyclic derivatives of nonmetal main-gr

38 [F-H-F](-), can be considered as containing hypervalent hydrogen.

39 halide), that undergo rapid homolysis of the hypervalent I-X bonds and generate (pseudo)halide radica

40 possibility of their rearrangements from the hypervalent (I-CF(3), I-SCF(3)) to the corresponding eth

41 In this study, hypervalent interactions are shown to provide colloidal

42 ploiting the ability of silicon to engage in hypervalent interactions with hard donor molecules.

43 e bonds at the phosphorus center, suggesting hypervalent involvement of extra-valence d-orbitals in t

44 Novel, original protocols include the use of hypervalent iodide carboxylates alone or in conjunction

45 ines the structure-property relationship for hypervalent iodide carboxylates and halide initiators in

46 Saponification of arnottin I and hypervalent iodide mediated spirocyclization provided an

47 The use of oxidants such as hypervalent iodine (e.g., ArIO), peracids (e.g., m-CPBA)

48 Hypervalent iodine (HVI) compounds are efficient reagent

49 routes: (1) a Cu(OTf)2 (0-5 mol %) catalyzed hypervalent iodine [PhI(OTf)2] mediated oxidative coupli

50 A thiol-alkynylation procedure utilizing the hypervalent iodine alkyne transfer reagent TIPS-ethynyl-

51 des onto tethered, unactivated alkenes using hypervalent iodine and Bronsted acids.

52 C-C bonds can be seamlessly accomplished by hypervalent iodine catalysed oxidative functionalisation

53 ticle- and metal organic framework-supported hypervalent iodine catalysts are also described.

54 Development of hypervalent iodine catalytic systems and discovery of hi

55 ntramolecular I...O interactions between the hypervalent iodine center and the sulfonyl oxygens in th

56 Despite the remarkable advancements in hypervalent iodine chemistry, exploration of bromine and

57 important recent achievement in the field of hypervalent iodine chemistry.

58 ularly important achievement in the field of hypervalent iodine chemistry.

59 ins was accomplished using palladium(II) and hypervalent iodine co-catalysis.

60 The hypervalent iodine co-catalyst was found to be critical

61 irst example of a structurally characterized hypervalent iodine compound with a relatively short iodi

62 These hypervalent iodine compounds are potentially valuable ox

63 The preparation, structure, and chemistry of hypervalent iodine compounds are reviewed with emphasis

64 ntific community as to the benefits of using hypervalent iodine compounds as an environmentally susta

65 Hypervalent iodine compounds as environmentally friendly

66 The ring and I: hypervalent iodine compounds avoid the issues of toxicit

67 O, N, C) bonding was analyzed in the related hypervalent iodine compounds based on the adaptive natur

68 ghly enantioselective reactions using chiral hypervalent iodine compounds represent a particularly im

69 new enantioselective reactions using chiral hypervalent iodine compounds represent a particularly im

70 ulation of the electronic structure of these hypervalent iodine compounds would be useful in establis

71 t represents the first example of metal-free hypervalent iodine electrocatalysis for C-H functionaliz

72 The developed hypervalent iodine electrocatalysis is applicable in bot

73 been established that the kinetically stable hypervalent iodine form (I-CF(3)) of the reagents is the

74 Chemical transformations promoted by hypervalent iodine in many cases are unique and cannot b

75 ere we demonstrate that anodically generated hypervalent iodine intermediates effectively couple inte

76 ial oxidation of electron-rich arenes by the hypervalent iodine is essential for the dimerization of

77 The realization of one-electron hypervalent iodine mechanisms provides synthetic opportu

78 nistic alternative to canonical two-electron hypervalent iodine mechanisms.

79 d phenyliodine(III) diacetate (PIDA) through hypervalent iodine mediated C(sp2)-C(sp2) bond formation

80 ccess is the electrochemical generation of a hypervalent iodine mediator using an "ex-cell" approach,

81 cipate will contribute to the development of hypervalent iodine mediators for synthetic electrochemis

82 ve dearomatizations commonly rely heavily on hypervalent iodine or heavy metals to provide the requis

83 iron(0) complexes has been achieved with the hypervalent iodine oxidant PIFA which was shown to be co

84 organic solvents and is a potentially useful hypervalent iodine oxidant.

85 ion) of indole in water in the presense of a hypervalent iodine oxidant.

86 Hypervalent iodine oxidants mediate this transformation,

87 afford complex reaction mixtures with other hypervalent iodine oxidants.

88 Morita-Baylis-Hillman adducts mediated by a hypervalent iodine reagent (IBX) to form beta-ketoesters

89 The cost-effective and readily accessible hypervalent iodine reagent (PIDA) easily promoted the ox

90 dative phenol dearomatizations mediated by a hypervalent iodine reagent and includes a novel route to

91 ative de-aromatization process mediated by a hypervalent iodine reagent from an inexpensive phenol co

92 fluoromethylation with a trifluoromethylated hypervalent iodine reagent in the presence of CuCN.

93 of a-oxyacylated vinyl ketones using Koser's hypervalent iodine reagent is reported.

94 tion efficiently cleaves the I-O bond of the hypervalent iodine reagent PhI(O(2)CCOAr)(2) formed thro

95 by reaction of the terminal alkyne with the hypervalent iodine reagent PhI(OAc)NTs(2) within a singl

96 Using a simple hypervalent iodine reagent PIDA as a mild oxidant and po

97 The combination of photocatalysis and hypervalent iodine reagent provides a practical approach

98 n oxidative ipso-rearrangement mediated by a hypervalent iodine reagent that enables rapid generation

99 Here we report a hypervalent iodine reagent that releases a potent hydrog

100 ed in situ in the presence of methanol and a hypervalent iodine reagent to form an active iminium spe

101 ive 1,2- and 1,3- alkyl shifts mediated by a hypervalent iodine reagent were performed on simple and

102 thiol, amine and alcohol nucleophiles with a hypervalent iodine reagent, (2,2-difluoro-ethyl)(aryl)io

103 (PhI(Phth)), a new metal-free and low toxic hypervalent iodine reagent, are the most remarkable nove

104 initiated by a combination of the Pd(II) and hypervalent iodine reagent, Dess-Martin periodinane to g

105 A hypervalent iodine reagent-based alpha-carbonyl dihaloge

106 ctron density on the aryl substituent of the hypervalent iodine reagent.

107 n is that the use of catalytic quantities of hypervalent iodine reagents (phenyliodine diacetate or D

108 ited for large scale preparations of the two hypervalent iodine reagents 1 and 2 for electrophilic tr

109 yzed alkoxy diazomethylation of alkenes with hypervalent iodine reagents and alcohols.

110 lpha-alkynylation of acyclic aldehydes using hypervalent iodine reagents and borohydride reduction.

111 Hypervalent iodine reagents are commonly used in synthet

112 ns (CPCs) with readily available alkynes and hypervalent iodine reagents as carbyne sources.

113 The role of hypervalent iodine reagents as oxidants has been widely

114 Unstable hypervalent iodine reagents can be prepared easily and c

115 A novel class of chiral hypervalent iodine reagents containing an alpha-tetralol

116 ldehyde autoxidation to aerobically generate hypervalent iodine reagents for a broad array of substra

117 yl ureas employing chiral, lactic acid-based hypervalent iodine reagents gives a facile synthesis of

118 ol for oxidative transformations mediated by hypervalent iodine reagents has been developed.

119 nt and reliable electrochemical generator of hypervalent iodine reagents has been developed.

120 ods based on electrophilic alkynylation with hypervalent iodine reagents have made acetylene synthesi

121 ding BP phenols by direct oxidation with the hypervalent iodine reagents IBX or TBI.

122 Synthetic uses of hypervalent iodine reagents in halogenation reactions, v

123 The use of the hypervalent iodine reagents in oxidative processes has b

124 aromatization conditions were attained using hypervalent iodine reagents instead of Pb(OAc)4.

125 The utility of hypervalent iodine reagents is often ascribed to the sel

126 Defined hypervalent iodine reagents of the general structure PhI

127 protocols are restricted to highly oxidative hypervalent iodine reagents or superstoichiometric metal

128 ily be transformed into classic bench-stable hypervalent iodine reagents through ligand exchange.

129 In the anodic oxidation of iodoarenes to hypervalent iodine reagents under flow conditions, the u

130 Phen)R(3)PAu(I)NTf(2) complexes with alkynyl hypervalent iodine reagents was built.

131 The reaction of flavanones with hypervalent iodine reagents was investigated with a view

132 Novel electron-deficient chiral hypervalent iodine reagents were prepared in good overal

133 We anticipate that aerobically generated hypervalent iodine reagents will expand the scope of aer

134 eliminations, oxidative fragmentation using hypervalent iodine reagents, reactions of donor-acceptor

135 eliminations, oxidative fragmentation using hypervalent iodine reagents, reactions of donor-acceptor

136 C-H bond cyclopropylation using diazomethyl hypervalent iodine reagents, styrenes, and paddlewheel d

137 (HFIP) or the use of more strongly oxidizing hypervalent iodine reagents, such as [bis(trifluoroaceto

138 Here, we generate hypervalent iodine reagents-a broadly useful class of se

139 e direct C-H arylation of enones mediated by hypervalent iodine reagents.

140 ared to previously reported iodoacetamide or hypervalent iodine reagents.

141 ne of several oxidation reactions enabled by hypervalent iodine reagents.

142 hway in the reaction of typical phenols with hypervalent iodine reagents.

143 ated derivatives by using gold catalysis and hypervalent iodine reagents.

144 of thiols using ethynyl benziodoxolone (EBX) hypervalent iodine reagents.

145 The oxidation with hypervalent iodine shows a regioselective transformation

146 This reaction involves hypervalent iodine species generated in situ from cataly

147 catalytic systems based on the generation of hypervalent iodine species in situ are also overviewed.

148 The chiral hypervalent iodine species is generated in situ from a c

149 anoparticles are selectively oxidized by the hypervalent iodine species PhICl(2), and catalyse a rang

150 antage of an electrochemical generation of a hypervalent iodine species, difluoro- (3)-tolyl iodane,

151 le enabling catalysis with in situ generated hypervalent iodine species, thereby eliminating chemical

152 cyclization and aza-Michael cyclization with hypervalent iodine to create various azaspirotricyclic s

153 irst C-bound ortho-carborane (oCb) supported hypervalent iodine(III) -IL(2) type species are reported

154 peptide, utilizes an underdeveloped class of hypervalent iodine(III) aryl substrates in a palladium-c

155 oacetate esters is achieved by a homogeneous hypervalent iodine(III) complex in non-superacidic (trif

156 that relies on the chemistry of spirocyclic hypervalent iodine(III) complexes, which serve as precur

157 Hypervalent iodine(III) compounds have found wide applic

158 ide, cyanate, and bromide) to yield unstable hypervalent iodine(III) compounds, PhIX2 (X = (pseudo)ha

159 yl-D-glucal 10, which removes the need for a hypervalent iodine(III) oxidant, we provide evidence for

160 The combination of hypervalent iodine(III) oxidants and ammonia sources has

161 sfer agent generated from the combination of hypervalent iodine(III) oxidants and ammonia.

162 ofluorination on the distinctive spirocyclic hypervalent iodine(III) precursor to give (18)F-fluorobe

163 The reaction employs a hypervalent iodine(III) reagent as an oxidant and bistos

164 Overall, this work demonstrates that the hypervalent iodine(III) reagent PhIO can act as a conven

165 The hypervalent iodine(III) reagent-induced the direct intra

166 nactivated olefins has been achieved using a hypervalent iodine(III) reagent.

167 ion of a monofluoroacetoxy ligand-containing hypervalent iodine(III) reagent.

168 is capable of generating CF(3) radicals from hypervalent iodine(III) reagents and directing them for

169 ng to a new type of sulfoximidoyl-containing hypervalent iodine(III) reagents in high yields.

170 ic parameters on the reaction performance of hypervalent iodine(III) reagents in the vicinal diaminat

171 eaction of N-(biphenyl)pyridin-2-amines with hypervalent iodine(III) reagents is investigated.

172 Hypervalent iodine(iii) reagents, which have already pro

173 rs under copper catalysis in the presence of hypervalent iodine(III), giving selectively the 5H-oxazo

174 This methodology uses an hypervalent iodine(III)-CF(2)CF(3) reagent, and mechanis

175 A hypervalent iodine(III)-mediated cross-dehydrogenative c

176 odoxybenzoic acid (IBX), a readily available hypervalent iodine(V) reagent, was found to be highly ef

177 Iodoxybenzoic acid (IBX), a highly versatile hypervalent iodine(V) reagent, was found to efficiently

178 Hypervalent iodine(V) reagents are a powerful class of o

179 pective summarizes synthetic applications of hypervalent iodine(V) reagents: 2-iodoxybenzoic acid (IB

180 A unique tetracoordinate hypervalent iodine-based compound was identified as the

181 bining the high cysteine chemoselectivity of hypervalent iodine-based ethynylbenziodoxolones (EBXs) w

182 the dynamic self-assembly and disassembly of hypervalent iodine-based macrocycles (HIMs) guided by se

183 unusually beneficial solvent for undertaking hypervalent iodine-initiated [2+2] cycloaddition of styr

184 ynthesis of sulfondiimidamides, exploiting a hypervalent iodine-mediated amination as the key step.

185 fully achieved through visible-light-induced hypervalent iodine-mediated C-H functionalization of bot

186 has been established through a photoinduced hypervalent iodine-mediated cross-dehydrogenative coupli

187 cycloisomerization, and another employing a hypervalent iodine-mediated de-aromatizing cyclization o

188 l motif common to the herqulines via initial hypervalent iodine-mediated dearomatization and a subseq

189 lic carbene (NHC)-mediated deoxygenation and hypervalent iodine-mediated decarboxylation.

190 insights into these understudied aspects of hypervalent iodine-mediated nitrogen atom insertion.

191 new protocols leveraging electrochemical and hypervalent iodine-mediated synthesis of alpha-ketothioa

192 ethod has been validated using two different hypervalent iodine-mediated transformations: (i) the oxi

193 complementary to extant methods that rely on hypervalent iodine.

194 process is achieved using in situ-generated hypervalent iodine.

195 "Hypervalent" iodine(III) derivatives have been establish

196 nks to the establishment of important chiral hypervalent iodines(III/V).

197 ation of difluoro enol silyl ethers based on hypervalent iodines.

198 as generated by the reaction of azide with a hypervalent iodonium alkynyl triflate and reacted in sit

199 metal-free (18)F-labeling method that uses a hypervalent iodonium(III) ylide precursor, to prepare th

200 RX Li(1+x)Mn(y)M(1-x-y)O(2) (y >= 0.5, M are hypervalent ions such as Ti(4+) and Nb(5+)) exhibit a gr

201 ptical spectrum of the ferric enzyme with no hypervalent iron intermediates detected.

202 The high electrophilicity of hypervalent iron oxo species is devised as a key to enab

203 idence from several laboratories points to a hypervalent iron-oxenoid species in P450-catalyzed oxyge

204 e first examples of complexes that feature a hypervalent kappa(2)-H2-H2SiPh2H silyl ligand and a chel

205 ocyclic molecules incorporating an atom of a hypervalent main-group element.

206 nts with double bonds are not categorized as hypervalent molecules owing to the zwitterionic nature o

207 ecules to explain the atomic coordination in hypervalent molecules that violates the electron-octet r

208 pling (i.e., reductive elimination) within a hypervalent, pentacarbon-ligated sigma-phosphorane furni

209 achieved under the Kita conditions using the hypervalent PIFA/BF3 reagent.

210 amine and alcohol oxidation by an iodine(V) hypervalent reagent (IBX).

211 to affect the reactivity of the iodine-based hypervalent reagents.

212 e time, we find a remarkable affinity of the hypervalent region to planarity for all reaction mechani

213 We further propose that hypervalent silicates form ion-pairs with pentanidinium

214 Oxidative [1,2]-Brook rearrangements via hypervalent silicon intermediates induced by photoredox-

215 Arylations using tin and hypervalent silicon reagents were compared.

216 potassium graphite reduction of the neutral hypervalent silicon-carbene complex L:SiCl4 {where L: is

217 Ph2SiH2 to afford a variety of novel silyl, hypervalent silyl, silane, and disilane complexes, as re

218 of the Sn net with other main group element hypervalent slabs.

219 d on the extension of the sigma-bond, in the hypervalent species our DFT calculations reveal the form

220 dure enables the easy aryl transfer from the hypervalent species under mild catalytic conditions with

221 nging transformations while more traditional hypervalent species, such as 2-iodoxybenzoic acid (IBX),

222 oteins may be attributed to the formation of hypervalent states of the heme iron.

223 nide materials, in terms of the behaviour of hypervalent structural units, and its implicit relations

224 rtunities provided by this exciting class of hypervalent substances.

225 /magnesium reagents generates underexploited hypervalent sulfurane intermediates that undergo selecti

226 Hypervalent tellurium compounds have a particular reacti

227 on deficient to hypercoordinate and formally hypervalent, the p-block elements represent an area to f

228 like fragment [Re2Cl4]2+ is modified by four hypervalent three-center/four-electron additions.

229 utilizes fluoroalkyl radicals generated from hypervalent Togni reagents for targeting aromatic residu

230 th the ligand-exchange and the redox steps a hypervalent twist is required for the reaction to procee

231 sed of three steps: (a) ligand exchange, (b) hypervalent twist, and (c) reductive elimination.

232 In this sense, Cs(+) resembles hypervalent Xe.