ライフサイエンスコーパス: hypervariable

1 their DNA structure and primary sequence are hypervariable.

2 In analogy with poliovirus, a hypervariable 5' untranslated region tract may affect vi

3 inical isolates by pyrosequencing within the hypervariable A region of the 16S rRNA gene was compared

4 and functional analyses identified 351 sites hypervariable across isolates and numerous putative regu

5 ecies revealed that the N-terminal domain is hypervariable among species yet is conserved with regard

6 In addition, we show that both hypervariable and conserved regions of pilin are not sup

7 pheral peptide residues and the roles of the hypervariable and germline CDR loops in engaging peptide

8 nd NA are directed against epitopes that are hypervariable and not against epitopes that are conserve

9 all, conserved functional sites on otherwise hypervariable antigens.

10 o the Xp/Yp telomere, each copy containing a hypervariable array of the DXYS14 minisatellite.

11 Using universal primers that amplify the hypervariable bacterial 16 S rRNA gene as a model system

12 thin filament proteins, and its sequence is hypervariable between fiber type and developmental isofo

13 ntriguing decarboxylation step, indicating a hypervariable biosynthetic machinery.

14 ich is composed of an invariant domain and a hypervariable C terminus, as a key component of self-rec

15 The hypervariable C-terminal domain (HVD) of Rabs is posttra

16 The CTT features a hypervariable C-terminal linker (CTL) and a conserved C-

17 e-directed mutagenesis now indicate that the hypervariable C-terminal region of beta5 plays no role i

18 ung, as determined by deep sequencing of the hypervariable CD3RbetaVJ region of the TCR.

19 CD1d affinities are further modulated by the hypervariable CDR3 beta loop, thereby defining a functio

20 receptor then contacts the peptide using the hypervariable CDR3 loops as the transition state decays

21 C ligand derives largely from the juxtaposed hypervariable CDR3 regions on the TCRalpha and TCRbeta c

22 On average, the hypervariable CDRH3 region was four nucleotides shorter

23 , it is unclear if affinity mutations in the hypervariable CDRs generally impact antibody stability a

24 Using the hypervariable chloroplast ndhF-rpl32 sequences of 604 sa

25 variations and the presence and structure of hypervariable chromosomal elements indicate that there i

26 Antibody paratopes are formed by hypervariable complementarity-determining regions (CDRH3

27 Hypervariable contingency loci and epigenetic switches i

28 In contrast, the hypervariable deletion protein was unable to elicit an i

29 at replacing ANDV residues 252 to 296 with a hypervariable domain (HVD) from MAPV N prevents IFNbeta

30 es demonstrated the critical function of the hypervariable domain (HVD) in EEEV nsP3 for the assembly

31 hese critical host factors interact with the hypervariable domain (HVD) of alphavirus nsP3.

32 Previously, we have demonstrated that the hypervariable domain (HVD) of CHIKV nsP3 contains linear

33 e of the host factors that interact with the hypervariable domain (HVD) of CHIKV nsP3.

34 lular proteins are largely determined by the hypervariable domain (HVD) of nsP3.

35 Our study demonstrates that the hypervariable domain (HVD) of VEEV nsP3 interacts with t

36 peting hypothesis is that the Rab C-terminal hypervariable domain (HVD) serves as a subcellular targe

37 ese nonstructural proteins, nsP3, contains a hypervariable domain (HVD), which demonstrates very low

38 of nsp2 (the PLP2 protease domain [OTU], the hypervariable domain [HV], the putative transmembrane do

39 The hypervariable domain of the EEEV nsP3 protein interacts

40 scovered that ANDV S386 and an ANDV-specific hypervariable domain permit ANDV N to inhibit IFN induct

41 ar domains: a conserved N-terminal domain, a hypervariable domain, and an acidic C-terminal domain.

42 rved N-terminal domain of VP90 but lacks the hypervariable domain, which forms the capsid surface spi

43 t can be applied as live vaccines.IMPORTANCE Hypervariable domains (HVDs) of alphavirus nsP3 proteins

44 those of other teams have demonstrated that hypervariable domains (HVDs) of the alphavirus nsP3 prot

45 e receptor and the surface (SU) glycoprotein hypervariable domains are required for binding affinity

46 Here, we report on the development of the hypervariable domains D1/D2 of the large ribosomal subun

47 of Env is particularly striking in the V1/V2 hypervariable domains.

48 ia their unstructured and membrane-anchored, hypervariable domains.

49 acids in length, with large surface-exposed hypervariable domains.

50 and gene copy number variation (CNV) at the hypervariable DRB locus within the MHC region to HPV ser

51 1918 and 2009 hemagglutinins, a site that is hypervariable due to immune selection.

52 uple), GTPases and proteolytic cascades with hypervariable effectors, which vary either by using a re

53 es were as variable as other accessible, non-hypervariable Env sites (p = 0.50, Mann-Whitney U-test)

54 mutations by acting like a blanket over the hypervariable epitope, thereby providing effective viral

55 In neutrophils, genes with hypervariable expression are found to be implicated in k

56 de a transmembrane receptor protein with two hypervariable extracellular regions similar to immunoglo

57 helping to control product chemistry in this hypervariable family of marine natural products.

58 We report a previously unidentified, hypervariable family of PDIs that represents the most di

59 re widely recognized than were extracellular hypervariable fragments.

60 three variable island regions, with the most hypervariable genes concentrated at one end of the genom

61 This novel family of hypervariable genes with conserved, repetitive, and alle

62 t strains identified, with (except for a few hypervariable genes) the EEHV2, EEHV3, and EEHV6 strains

63 by less than 1% within populations, even in hypervariable genome regions, and by 42-71% between popu

64 ndings uncover a novel and cryptic source of hypervariable genomic diversity with global regulatory c

65 understanding floral scent variation in this hypervariable genus is its geographically diverse intera

66 embly and novel motif-based genotyping in 12 hypervariable HCMV genes.

67 Specific mutations within the hypervariable herpes simplex virus (HSV) gene thymidine

68 the largely conserved HLA-A*0201-M158and the hypervariable HLA-B*3501-NP418antigens.

69 Kupffer cell interaction is mediated by the hypervariable (HVR) loops of the virus hexon protein, we

70 e consisting of an extracellular region with hypervariable Ig domains, a transmembrane domain, and a

71 Adaptive immunity in humans is provided by hypervariable Ig-like molecules on the surface of B and

72 The described homopolymer is hypervariable in length, varying from 12 to 17 bp in the

73 PMDs are hypervariable in methylation level, size and distributio

74 These studies reveal sequences upstream, hypervariable in the human population (HVR3), and downst

75 Because residues 418 to 426 of the hypervariable influenza A virus nucleoprotein (NP(418-42

76 BorreliaBase allows online identification of hypervariable lipoprotein genes, potential regulatory el

77 Unexpectedly, other hypervariable loci in our data were in previously undesc

78 Most of the hypervariable loci were linked to genes encoding RTs of

79 he capability to selectively bind and enrich hypervariable, long or repetitive sequences.

80 ns of Africa was therefore surprising as one hypervariable loop contains the entire collagen-binding

81 eir concave surface, in addition to a unique hypervariable loop in the C-terminal LRR capping module.

82 ht chains, the majority of CDR-L3 [the third hypervariable loop of the light chain variable domain (V

83 ally divergent face of the protein formed by hypervariable loop segments, confirming that TRIM5alpha

84 ity (together with the local dynamics of the hypervariable loop within domain 3) could facilitate rec

85 riations in the common core and emergence of hypervariable loops extending from the core contributed

86 me the coding sequences for the two external hypervariable loops in the protein.

87 Substitution of two hypervariable loops in the spacer domain of ADAMTS-5 (re

88 3 our results suggest that the spacer domain hypervariable loops may exercise significant control of

89 The hypervariable loops of ADAMTS-5 are shown to be importan

90 ity in structure is most apparent in the six hypervariable loops of the complementarity-determining r

91 ed of immunoglobulin (Ig) domains containing hypervariable loops that bind antigen.

92 Antibodies recognize antigens through six hypervariable loops, five of which have a limited set of

93 e heavy and light chain each providing three hypervariable loops, which are varied to generate divers

94 ndicated only for the CDR3alpha and CDR3beta hypervariable loops.

95 The haplotigs accurately characterized the hypervariable major histocompatability complex region as

96 creased combinations of the newly identified hypervariable microdomains.

97 Furthermore, these motifs are found in hypervariable minisatellites and are clustered in the br

98 study reveals that a previously undescribed hypervariable molecule bearing three extracellular domai

99 orphisms within the Helicobacter pylori CagL hypervariable motif (CagLHM) in gastric cancer-associate

100 By exploiting the hypervariable nature of virulence genes and clustered re

101 Deletion of the TnT hypervariable NH2-terminus preserved binding to troponin

102 Amino acid changes in the hypervariable part of G protein may have altered functio

103 n-specific splice variant repertoires of the hypervariable pattern recognition receptor AgDscam.

104 al fusion of a reporter lacZ fragment to the hypervariable poly-Psi domain facilitated measurement of

105 These fast evolving proteins both have hypervariable positions, which are under diversifying se

106 Here we designed a vaccine using the hypervariable receptor-binding domain (RBD) of viral hem

107 We aligned time-stamped second hypervariable region (330 bp) of G-gene sequence data (g

108 kines was localized to 40 amino acids in the hypervariable region (amino acids 301-340) of the protei

109 me of the hepatitis E virus (HEV) contains a hypervariable region (HVR) in ORF1 that tolerates small

110 simulations highlight that the membrane and hypervariable region (HVR) interact with both alpha- and

111 rnesylated and positively charged C-terminal hypervariable region (HVR) is critical to its oncogenic

112 man ribosomal protein S17 (RPS17) within the hypervariable region (HVR) of the HEV ORF1 protein.

113 Comparative sequence analysis revealed a hypervariable region (HVR) with extensive sequence varia

114 cently, insertions and rearrangements of the hypervariable region (HVR) within the HEV genome, allowi

115 -Ras4B is predominantly autoinhibited by its hypervariable region (HVR), whereas the GTP-bound state

116 Previous studies have shown that the first hypervariable region (V1 loop) is immunogenic on soluble

117 ne hypervariable region of mtDNA, designated hypervariable region 1 (HV1).

118 Hypervariable region 1 (HVR1) (amino acids [aa] 384 to 4

119 edly reduced binding when amino acids within hypervariable region 1 (HVR1) and at sites approximately

120 of viral envelope glycoprotein E2, including hypervariable region 1 (HVR1) and N-linked glycans.

121 Hypervariable region 1 (HVR1) is genetically diverse and

122 Interestingly, the E2 hypervariable region 1 (HVR1) mutation T385P caused (i)

123 which we find maps to a specific site within hypervariable region 1 (HVR1) of AdV5 hexon, has no appa

124 f HCV and shielding of important epitopes by hypervariable region 1 (HVR1) of E2 are believed to be m

125 Hypervariable region 1 (HVR1) of hepatitis C virus (HCV)

126 Furthermore, replacement of hypervariable region 1 (HVR1) of the Ad capsid proteins

127 Evolutionary rates in the hypervariable region 1 (HVR1) region of the E2 gene were

128 Remarkably, sequences of hypervariable region 1 (HVR1) remained stable for up to

129 to Huh7.5 cells to produce a quasispecies of hypervariable region 1 (HVR1) that mimicked that circula

130 Hypervariable region 1 (HVR1) variability is frequently

131 Hypervariable region 1 (HVR1) within viral envelope prot

132 We obtained sequences from the HCV hypervariable region 1 (HVR1), using end-point limiting-

133 Using highly NAb-sensitive hypervariable region 1 (HVR1)-deleted HCVcc, H77/JFH1(De

134 1a)/JFH1 or the highly antibody-susceptible hypervariable region 1 (HVR1)-deleted variants H77/JFH1D

135 tify AR3A resistance substitutions that have hypervariable region 1 (HVR1)-dependent effects on HCV v

136 that major outer membrane protein 1 (OMP-19) hypervariable region 1 (HVR1)-specific human monoclonal

137 instead of the well-known immunodominant E2 hypervariable region 1 (HVR1).

138 plotypes that had identical sequences in the hypervariable region 1 (HVR1).

139 s-immunoreactivity among variants of the HCV hypervariable region 1 (HVR1).

140 d, ranging from high diversity (the envelope hypervariable region 1 [HVR1]) to almost no diversity (t

141 alizing epitopes on the E1 N-terminus and E2 hypervariable region 1 did not differ significantly.

142 on of SR-BI governed by specific residues in hypervariable region 1 of E2 leading to enhanced cell en

143 terized epitopes on E1/E2, especially to the hypervariable region 1 of E2.

144 out the envelope genes, primarily within the hypervariable region 1 of E2.

145 Next-generation sequencing data from the hypervariable region 1 of HCV were analyzed using Global

146 is virus (VSV)/HCV pseudotype model that the hypervariable region 1 of the HCV E2 envelope glycoprote

147 Most NAbs recognize hypervariable region 1 on E2, which undergoes frequent m

148 equence revealed amino acid substitutions in hypervariable region 1 that were responsible for a drama

149 yethylene glycol to a specific site in hexon hypervariable region 1 yielded vector particles that wer

150 Deletion of hypervariable region 1, a region previously proposed to

151 s, suggesting purifying selection, except in hypervariable region 1, where positive selection pressur

152 for immunogenicity in mice, with and without hypervariable region 1, which is an immunogenic region a

153 nfectivity of J6(2a) and J8(2b) with deleted hypervariable region 1.

154 Sequencing of hypervariable region 4 poorly captures skin commensal mi

155 a single immunization of chimeric rAd5 hexon hypervariable region 48 (rAd5HVR48) vectors expressing S

156 MiSeq and Roche454 platforms using the V3-V4 hypervariable region also showed a high level of concord

157 membrane but is tethered via its C-terminal hypervariable region and carboxymethylated farnesyl moie

158 Analysis of the szp gene hypervariable region and the 16S-23S rRNA intergenic spa

159 The hemagglutinin (H) gene and hypervariable region between the fusion and matrix genes

160 3 million 16S rRNA sequences spanning the V4 hypervariable region by pyrosequencing.

161 While the hypervariable region CDR3 often mediates much of the spe

162 ith bNAb sensitivity, including amino acids, hypervariable region characteristics, and clade effects

163 extension containing a His- and Asp/Glu-rich hypervariable region followed by a highly conserved sequ

164 d for identification of the 16S rRNA gene V3 hypervariable region from Escherichia coli genomic DNA.

165 two primer pairs demonstrated that the V3-V4 hypervariable region had significantly better capture of

166 etion variants of UreG demonstrated that the hypervariable region has a minor impact on activation ef

167 Here we show that the human mitochondrial hypervariable region II can function as a molecular fing

168 esent high-throughput sequencing analysis of hypervariable region II for spatial resolution of the co

169 e induction of Gal-3 expression requires the hypervariable region in the extracellular domain of beta

170 sitive to GM-CSF, mutations within the N-Ras hypervariable region induced N-Ras mislocalization and a

171 in primary structure within the immunogenic hypervariable region microdomains and tested whether the

172 ted nanoclustering of H-ras helix alpha4 and hypervariable region mutants that have different bona fi

173 S ribosomal RNA amplicon sequences in the V4 hypervariable region obtained from 492 studies worldwide

174 .1 M bacterial pyrotag sequences from the V6 hypervariable region of 16S rRNA genes from 38 influent

175 human hepatoma cells when inserted into the hypervariable region of a genotype 1 strain, but this ch

176 We analyzed the V4 hypervariable region of bacterial 16S rRNA genes with Il

177 plified by using primers specific for the V6 hypervariable region of bacterial 16s rRNA.

178 a crucial but commonly coded residue in the hypervariable region of CDR3 provide the basis for the s

179 rough elevated signal produced to the unique hypervariable region of each - 2/114 in HL-60, 3/114 in

180 oduplex tracking assay targeted to the V1/V2 hypervariable region of env.

181 The hypervariable region of K-Ras4B binds specifically to th

182 tration calorimetry, we demonstrate that the hypervariable region of K-Ras4B contributes in a major w

183 histocompatibility antigens, we examined one hypervariable region of mtDNA, designated hypervariable

184 r results show that in the murine model, the hypervariable region of PilE is required to activate imm

185 ly bound to the CAAX motif in the C-terminal hypervariable region of Rac1, and then inhibited Rac1 me

186 Sequence variations within the hypervariable region of Ras isoforms underlie differenti

187 Amplicons were sequenced (V3-V4 hypervariable region of the 16S rRNA gene) using MiSeq (

188 zed by bar-coded pyrosequencing of the V3-V5 hypervariable region of the 16S rRNA gene, defining 662

189 ent study, using pyrosequencing of the V1-V2 hypervariable region of the 16S rRNA gene, reported find

190 We were able to assemble the D1-D2 hypervariable region of the 28S ribosomal RNA (rRNA) of

191 This virus was unusual in that the hypervariable region of the adapted virus contained a 17

192 idase subunit 1 gene of nematodes and the V3 hypervariable region of the bacterial 16 s ribosomal RNA

193 d a tag-sequencing strategy targeting the V6 hypervariable region of the bacterial small-subunit (16S

194 ndings indicate that sequence variation in a hypervariable region of the degron affects JAZ stability

195 s a 5-aa sequence motif in the third allelic hypervariable region of the HLA-DRbeta chain.

196 This residue is located in the C-terminal hypervariable region of the proteins and is not conserve

197 several single-nucleotide substitutions in a hypervariable region outside the SAM-binding core can al

198 g GC and AT rich motifs correlated well with hypervariable region recombination sites across the HAdV

199 The K-Ras4A hypervariable region sequence is positively charged, in

200 ing more than 1.7 million bacterial 16S rRNA hypervariable region sequences from 52 to 56 samples per

201 in the plasma membrane via lipid-tethers and hypervariable region side-chain interactions in distinct

202 n reaction was performed to amplify 16S rRNA hypervariable region V3-V4, and constructed libraries we

203 had greater accuracy than sequencing of the hypervariable region V4 in determining genus and species

204 The 16S RNA hypervariable region V4 was sequenced on Illumina MiSeq.

205 sequencing based on the bacterial 16 S rRNA hypervariable region V4.

206 gG variants containing the EHV-1 hypervariable region were able to bind chemokines and we

207 Sequence diversities in the G protein second hypervariable region were observed in the duplicated reg

208 tatic interactions of its positively charged hypervariable region with anionic lipids.

209 -DR alleles sharing amino acids at the third hypervariable region with DRB1*0401(shared epitope) are

210 he majority of their genomes but contained a hypervariable region with extensive divergence.

211 e, and -f were mapped within the nsp2 middle hypervariable region, but no conserved cleavage sites co

212 Modifications to the hypervariable region, including single-amino acid substi

213 Results obtained from the V3-V4 16S rRNA hypervariable region, sequencing on the MiSeq and Roche4

214 key changes to the lipidation pattern of the hypervariable region, suggest that dimerization is a gen

215 ferences between RAS isoforms lie within the hypervariable region, the additional confinement of KRAS

216 mice, suggesting that in the absence of the hypervariable region, the conserved regions of PilE alon

217 The HCV E2 hypervariable region-1 was amplified using nested revers

218 nt cells, and we mapped this activity to the hypervariable region.

219 A gene sequences by more than 80% for the V4 hypervariable region.

220 lyzed using 16S rRNA sequencing of the V3-V4 hypervariable region.

221 arnesylated-methylated KRAS4b, including the hypervariable region.

222 egments from multiple alleles to form unique hypervariable regions (HVR).

223 Replacing hypervariable regions (HVRs) 1, 2, 4, and 5 with the equ

224 ing antibodies typically recognize M protein hypervariable regions (HVRs) and confer narrow protectio

225 at CaM preferentially binds unfolded K-Ras4B hypervariable regions (HVRs) and not alpha-helical HVRs.

226 rface-exposed regions of the capsid, such as hypervariable regions (HVRs) I to IX of VP3.

227 us catalytic domains and flexible C-terminal hypervariable regions (HVRs) that differ across Ras isof

228 (NAbs) directed primarily against the hexon hypervariable regions (HVRs).

229 FX binds to the adenovirus hexon hypervariable regions (HVRs).

230 talytic or globular domains, plus C-terminal hypervariable regions (HVRs).

231 We used DNA from hypervariable regions (V1-V2) of 16S bacteria rRNA to de

232 tes microbial communities, but sequencing of hypervariable regions 1-3 of the 16S rRNA gene provides

233 hanges both within the traditionally defined hypervariable regions and downstream, near the 3'-end of

234 r multiple markers such as the 16S rRNA gene hypervariable regions are available, MetAmp improves the

235 Only the C-terminal hypervariable regions differ significantly.

236 cally infected individuals by sequencing the hypervariable regions encoding TCR alpha and beta polype

237 identified in at least two of five examined hypervariable regions for every virus, suggesting the ev

238 g it into our Ad5 vector containing all nine hypervariable regions from Ad43, Ad5.H(43m-43), increase

239 m TRUST to extract the B cell immunoglobulin hypervariable regions from bulk tumor RNA-sequencing dat

240 the specific amplification of 18s rRNA gene hypervariable regions from eukaryotic microbes: anneal-i

241 Pyrosequencing of amplicons for hypervariable regions in the 16S rRNA gene generated tax

242 16S rRNA per cells and also the presence of hypervariable regions in the genes.

243 unique, sexually dimorphic motifs in the TCR hypervariable regions in the SjS(S) mice.

244 ligonucleotide gold nanoprobe for one of the hypervariable regions of 16S rRNA gene.

245 nd ESPRIT-Tree, sequence data from different hypervariable regions of 16S rRNA were used and binning

246 serotype 5 (Ad5) vector containing the hexon hypervariable regions of Ad serotype 48 (Ad48) and expre

247 hexon-modified vector that carried the hexon hypervariable regions of Ad48, indicating that the SP mu

248 In these hybrid glycoproteins the hypervariable regions of EHV-1 gG, a vCKBP, and the clos

249 Finally, features of the first and second hypervariable regions of gp120 (V1V2) may be critical fo

250 Illumina MiSeq sequencing of the V3-V4 hypervariable regions of the 16 S rRNA gene was used to

251 oes is efficiently surveyed by sequencing of hypervariable regions of the 16s ribosomal RNA (rRNA) ge

252 lyzed by FLX+ pyrosequencing of the V1 to V4 hypervariable regions of the 16S rRNA gene and polymeras

253 Unique melt profiles generated from multiple hypervariable regions of the 16S rRNA gene for 100 clini

254 DNA was amplified with primer pairs covering hypervariable regions of the 16S rRNA gene: primers 63F

255 an interaction between the FX Gla domain and hypervariable regions of the hexon surface.

256 Conventional genotyping methods target small hypervariable regions of the M. bovis genome and provide

257 is phosphorylated at sites clustered in two hypervariable regions of the protein.

258 ences between D1 domains are concentrated in hypervariable regions on the front sheet strands of the

259 s in the mtDNA control region, including the hypervariable regions typically sequenced in a forensic

260 two species by pyrosequencing the 16S V1-V3 hypervariable regions using the 454 GS FLX Titanium plat

261 pected microbial profiles, sequencing of the hypervariable regions V1-V3 of the 16S ribosomal RNA gen

262 The 16s rRNA hypervariable regions V3 and V6 were amplified from Kleb

263 analysis indicates that alternative 16S rRNA hypervariable regions will present similar challenges, w

264 s identified as phage morons were located in hypervariable regions within individual SVMs, indicating

265 l seven HAdV species, confirmed the uniquely hypervariable regions within species.

266 ure as determined via 18S rRNA (V4 and V8-V9 hypervariable regions) and 16S rRNA (V1-V3) gene amplico

267 not exclusively, directed against the hexon hypervariable regions.

268 is is further complicated by the presence of hypervariable regions.

269 of hepatitis C virus (HCV) contains several hypervariable regions.

270 regions, including splice site acceptors and hypervariable regions.

271 in the conserved positions, and GS"N in the hypervariable regions.

272 S rRNA gene primer sets, targeting different hypervariable regions.

273 The hypervariable reiterative repeat regions in the US1 and

274 Ebola, a hypervariable RNA virus causing fatalities of up to 90%

275 As expected, the third hypervariable segment (CDR3), formed by the rearrangemen

276 A hypervariable segment, residing between the atp6 and rrn

277 alyzed 815,377 autosomal SNPs, mitochondrial hypervariable segments I and II, and 36 Y-chromosome STR

278 r 32 lineage-defining mitochondrial SNPs and hypervariable sequence (HVS) 1, Tamil castes have higher

279 Neutrophil-specific DNA methylation hypervariable sites are enriched at dynamic chromatin re

280 Two 18S rDNA hypervariable sites, the V4 and V8-V9 regions, were ampl

281 ed to identify both conserved SLs and unique hypervariable SLs within Heterodera glycines, the soybea

282 However, exon variation within the hypervariable splice region resulted in significant diff

283 ison, deletion of loop 2, which contains the hypervariable splice region, did not reduce the ability

284 Hypervariable subregion 1 (HV-1) is localized to an inte

285 t clustered exclusively within HV-1 or other hypervariable subregions.

286 After exclusion of the hypervariable subtelomeric regions, a high-quality core

287 CBD uses the repetitive nature of hypervariable tag datasets and well-established compress

288 etween gastrointestinal tract microbiota 16S hypervariable tag datasets.

289 btained from carefully curated deep 16S rRNA hypervariable tag sequencing data.

290 composition through the use of 16S rRNA gene hypervariable tag sequencing has profound health implica

291 t microbial populations were generated using hypervariable tag sequencing of the V3-V5 region of the

292 aoperatively obtained samples using 16S rDNA hypervariable tag sequencing.

293 gh a steric gating mechanism involving their hypervariable tails.

294 this family of genes are characterized by a hypervariable "toxin" region capable of encoding a wide

295 Genotypic linkage was maintained within hypervariable UL73/UL74 and RL12/RL13/UL1 loci for virus

296 rived from next-generation sequencing of the hypervariable V3 region of the 16S ribosomal RNA gene sh

297 acer using two approaches, pyrosequencing of hypervariable V3-V5 regions of the 16S rRNA gene and who

298 f linear peptides corresponding to the third hypervariable (V3) loop of gp120 failed to inhibit serum

299 Pro(313)-Gly(314)-Arg(315) arch of the third hypervariable (V3) loop of the HIV-1 surface glycoprotei

300 associated multigene families, including the hypervariable var genes, is broadly conserved, but P. fa