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2 or constituent of iron corrosion scales) and hypochlorous acid (HClO, the main reactive chlorine spec
4 vely modified by peroxynitrite (ONOO(-)) and hypochlorous acid (HOCl) and by activated monocytes and
5 nvironments leads to the emission of gaseous hypochlorous acid (HOCl) and chlorine (Cl(2)), both of w
7 gh protein degradation by neutrophil-derived hypochlorous acid (HOCl) and eosinophil-derived hypobrom
8 t of fibrin polymerization after exposure to hypochlorous acid (HOCl) and increased methionine oxidat
11 trated selective turn-on fluorescence toward hypochlorous acid (HOCl) and successfully visualized end
12 specific end product of the reaction between hypochlorous acid (HOCl) and tyrosine residues of protei
13 roxide (O2(.-)), hydroxyl radicals (.OH) and hypochlorous acid (HOCl) assays, and their potential as
15 d cyt c was reacted with an excess amount of hypochlorous acid (HOCl) at pH 7.4, the peroxidase activ
16 operoxidase generates significant amounts of hypochlorous acid (HOCl) at sites of inflammation to inf
17 uction of potent halogenating agents such as hypochlorous acid (HOCl) by the myeloperoxidase-hydrogen
18 ted whether the potent antibacterial oxidant hypochlorous acid (HOCl) contributes to killing of Mycob
20 xidation product of nitric oxide (.NO), with hypochlorous acid (HOCl) forms reactive intermediate spe
23 microbial role, hydrogen peroxide (H2O2) and hypochlorous acid (HOCl) function as inflammatory mediat
27 02 and chloride, and was mimicked by reagent hypochlorous acid (HOCl) in the absence of enzyme, sugge
29 recently showed that the neutrophil oxidant hypochlorous acid (HOCl) inhibits VWF proteolysis by ADA
35 scrimination between changes in H(2)O(2) and hypochlorous acid (HOCl) levels in live RAW264.7 macroph
36 es that generate the reactive oxygen species hypochlorous acid (HOCl) or hydrogen peroxide (H(2)O(2))
42 etric method was developed and validated for hypochlorous acid (HOCl) scavenging activity estimation
43 generates controlled, low concentrations of hypochlorous acid (HOCl) suitable for killing biofilm co
45 obe (Hypo-SiF) designed for the detection of hypochlorous acid (HOCl) using a silicon analogue of flu
46 idase required H2O2 and Cl-, suggesting that hypochlorous acid (HOCl) was an intermediate in the reac
47 were each fully destroyed by only 100 ppm of hypochlorous acid (HOCl) within 30 s, which was the shor
48 gosomes where it catalyzes the production of hypochlorous acid (HOCl), a potent chlorinating oxidant.
49 se uses hydrogen peroxide (H2O2) to generate hypochlorous acid (HOCl), a potent cytotoxic oxidant.
50 interaction of TIMPs with MMPs might involve hypochlorous acid (HOCl), a potent oxidant produced by t
51 or controlling enzyme activity might involve hypochlorous acid (HOCl), a potent oxidant produced by t
52 e is the only human enzyme known to generate hypochlorous acid (HOCl), a potent oxidizing agent, at p
57 we developed NR-HOCl-TFMU, which responds to hypochlorous acid (HOCl), an analyte detected in acute m
58 a combination of molecular chlorine (Cl(2)), hypochlorous acid (HOCl), and hypochlorite (OCl(-))) are
59 as a specific product when HE was exposed to hypochlorous acid (HOCl), chloramines, MPO/H2O2/chloride
60 Bleach generates toxic species including hypochlorous acid (HOCl), chlorine (Cl(2)), and chlorami
62 e protein that converts hydrogen peroxide to hypochlorous acid (HOCl), compared with sensitive AML ce
63 ygen species within the phagosome, including hypochlorous acid (HOCl), formed by the oxidation of chl
64 n of alpha-amino acids to aldehydes requires hypochlorous acid (HOCl), formed from H2O2 and chloride
67 olonization on mucosal barrier epithelia are hypochlorous acid (HOCl), hypobromous acid (HOBr) and hy
68 trite, can be oxidized by monochloramine and hypochlorous acid (HOCl), potentially leading to rapid m
76 lic compounds when water is disinfected with hypochlorous acid (HOCl), there is still considerable un
77 s investigated in wild-type BALB/c mice with hypochlorous acid (HOCl)-induced SSc by ELISA and Wester
90 1% wt/vol) effectively scavenges the oxidant hypochlorous acid (HOCl; 1 to 7.5 mM) in vitro, and prot
91 2020 hydrochloric acid, chlorine nitrate and hypochlorous acid abundances are in good agreement with
93 de, chlorine nitrate, chlorine monoxide, and hypochlorous acid and decreases in ozone, nitrogen dioxi
94 c cleavage of free available chlorine (i.e., hypochlorous acid and hypochlorite) to generate hydroxyl
96 n chloride and hydrogen peroxide to generate hypochlorous acid and other reactive compounds that have
98 hT), which results from the reaction between hypochlorous acid and taurine, is a powerful and less di
101 uncontrolled the extracellular generation of hypochlorous acid by MPO can cause bystander tissue dama
102 ng chronic inflammation, neutrophil-secreted hypochlorous acid can damage nearby cells inducing the g
103 from mast cells and the oxidation of HDL by hypochlorous acid can impair the function of phospholipi
104 oA1(WT) conditioned media in the presence of hypochlorous acid emulating conditions of oxidative stre
105 icate that electrolysis reactions generating hypochlorous acid from chloride are likely a main contri
106 ns is myeloperoxidase (MPO), which generates hypochlorous acid from Cl(-) and hydrogen peroxide.
107 radical, reactive nitrogen intermediates and hypochlorous acid in LDL oxidation and lesion formation
108 osyl radical, reactive nitrogen species, and hypochlorous acid in LDL oxidation in the human artery w
110 incubation with tert-butyl hydroperoxide and hypochlorous acid in vitro, we identified additional cov
111 sence of chlorotyrosine in the cell lysates, hypochlorous acid is hypothesized to be the chemical age
113 iments, where the oxidation was induced with hypochlorous acid or by exposure to activated neutrophil
116 xidation of low-density lipoprotein (LDL) by hypochlorous acid produces a modified form (HOCl-LDL) ca
117 oxidase regulation, magnitude of oxidant and hypochlorous acid production, and their repertoire of se
121 myeloperoxidase-containing leukocyte-derived hypochlorous acid targeting the vinyl ether bond of plas
122 acid that interacts with the potent oxidant hypochlorous acid to form the less toxic and more stable
123 chieve inactivation: UV, singlet oxygen, and hypochlorous acid treatments generally render the genome
124 ively produced toxicity in bacteria, whereas hypochlorous acid was nonselectively toxic to both bacte
126 DPPH, superoxide and hydroxyl radicals, and hypochlorous acid), and inhibitory activity against chol
127 s (ROS; peroxyl radical, superoxide radical, hypochlorous acid), cytotoxicity assay (MTT) and quantif
128 otonated conjugates (i.e., neutral water and hypochlorous acid), which are much weaker but more predo
129 scission is a strong function of exposure to hypochlorous acid, (iii) the ratio between amide links b
130 ing with an antibody to proteins modified by hypochlorous acid, a characteristic product of the enzym
133 s hydrogen peroxide and chloride to generate hypochlorous acid, a potent bactericidal oxidant in vitr
134 defense systems is their ability to generate hypochlorous acid, a potent microbicide, by reacting oxi
137 t in the rheumatoid joint (hydroxyl radical, hypochlorous acid, and peroxynitrite) were used for modi
138 active species hydrogen peroxide (H(2)O(2)), hypochlorous acid, and singlet oxygen are generated.
139 ghly damaging species, hydroxyl radicals and hypochlorous acid, from hydrogen peroxide contributed to
140 tive at micromolar concentrations to bleach (hypochlorous acid, HOCl), a potent antimicrobial produce
141 n of potent antimicrobial oxidants including hypochlorous acid, human myeloperoxidase (MPO) plays a c
142 uding H2O2, hydroxyl radical, peroxynitrite, hypochlorous acid, hypobromous acid, and hypothiocyanous
143 trols for all the tested methods, except for hypochlorous acid, in which lemon juice displayed higher
144 robes for monitoring myeloperoxidase-derived hypochlorous acid, including boronate-, aminophenyl- and
146 d by five common virucidal agents (heat, UV, hypochlorous acid, singlet oxygen, and chlorine dioxide)
147 ide ion and little affected by scavengers of hypochlorous acid, suggesting that the reactive agent is
148 idase converting H(2)O(2) to highly reactive hypochlorous acid, we hypothesized that gene variants co
149 ile present at alkaline pH and electrophilic hypochlorous acid, which decreases in abundance above it
151 MPO-specific biomarkers 3-chlorotyrosine and hypochlorous acid-modified proteins increase in the brai
152 zed the sites of chlorination at tyrosine in hypochlorous acid-treated hemoglobin by an accurate mass
160 II, we reacted hydrogen peroxide (H(2)O(2)), hypochlorous acid/hypochlorite (HOCl/OCl(-)), and single
163 (AOT) that uses UV/H(2)O(2) integrated with hypochlorous species exhibits great potential in removin
164 on the reaction kinetics of H(2)O(2) and the hypochlorous species, making it a highly suitable candid
165 made to study the reactions of H(2)O(2) with hypochlorous species, there exist great discrepancies in