ライフサイエンスコーパス: hypoxic

1 tumors are poorly vascularized and severely hypoxic.

2 1 mmHg), had them perform normoxic and acute hypoxic (15% inspired oxygen) maximal exercise tests, an

3 to four DO levels, ranging from normoxic to hypoxic (8.7, 6.0, 4.1, and 2.2 mg O(2) /L).

4 re, we found that BbOhmm negatively affected hypoxic adaptation in the insect haemocoel while regulat

5 To overcome a hypoxic and acidic microenvironment, the tumor microenvi

6 ainly oxidize ammonia to nitrite, whereas in hypoxic and anoxic environments reduction of both ammoni

7 ows, cells at the spheroid centre may become hypoxic and die, forming a necrotic core.

8 sues by inhibiting antitumor immune cells in hypoxic and extracellular adenosine-rich tumors that are

9 ing unique metabolic differences between the hypoxic and ischemic hearts.

10 alpha nuclear translocation occurred both in hypoxic and non-hypoxic ATM suggesting that both hypoxic

11 eq and RNA-seq data on cultured HUVECs under hypoxic and normoxic conditions.

12 tion, invasion, and spheroid formation under hypoxic and normoxic conditions.

13 e blunted ET-1-induced contraction of UtA in hypoxic and normoxic dams equivalently.

14 in a significant increase in sensitivity to hypoxic and oxidative stress.

15 xic and non-hypoxic ATM suggesting that both hypoxic and pseudohypoxic stimuli activate HIF-1alpha an

16 association of different lipid species with hypoxic and viable tissue within the tumour, and hence m

17 At that time, she became hypoxic and was intubated for airway protection.

18 ur microenvironment that is commonly acidic, hypoxic and/or depleted of critical nutrients required b

19 Polycystic kidneys are hypoxic, and oxidative stress activates TMEM16A.

20 Therefore, we reveal a key step regulating hypoxic angiogenesis and highlight the importance of nuc

21 on to ethanolic fermentation as the severely hypoxic/anoxic core became a progressively greater propo

22 Moreover, our new estimates of mean summer hypoxic area changed by >10% in a majority of years, rel

23 (+) epicardium-derived cells but only in the hypoxic area of infarcted hearts.

24 The fusion-based approach also reduces hypoxic area uncertainties by 11% on average and up to 4

25 pports the evidence that modern expansion of hypoxic areas and its effect on organic carbon burial ma

26 We found that by 2030 the extent of hypoxic areas would increase up to 5% in China seas unde

27 anslocation occurred both in hypoxic and non-hypoxic ATM suggesting that both hypoxic and pseudohypox

28 ified oligodendroglial-specific responses to hypoxic brain injury, and uncovered molecular mechanisms

29 genic factors including VEGFA and ANGPTL4 in hypoxic breast cancer cells by increasing recruitment of

30 Therefore, sEVs released by hypoxic breast cancer cells reprogram mitochondrial dyna

31 ctively, our data suggest that patients with hypoxic breast tumors and hypomethylated EGFR status may

32 ping individualized approaches to reduce the hypoxic burden in this delicate phase.

33 pro-angiogenic and pro-migratory function of hypoxic CAFs by decreasing secretion of the pro-angiogen

34 uencing (scRNA-seq) of the tumors identified hypoxic cancer cells with inhibited glycogen breakdown,

35 estructive effects against both normoxic and hypoxic cancers.

36 Donor pigs underwent hypoxic cardiac arrest (DCD) followed by 15 minutes of w

37 ILF3 expression in CD31(+) capillaries of hypoxic cardiac tissue was detected by immunohistochemis

38 Although transcriptional changes in hypoxic cardiomyocytes are well studied, little is known

39 crease of PCSK6 on mRNA and protein level in hypoxic cardiomyocytes.

40 e characterized by intratumoral hypoxia, and hypoxic cells are associated with the transformation to

41 changed (64)Cu-ATSM signal, but treatment of hypoxic cells with redox-active drugs resulted in a more

42 In hypoxic cells, this HIF-1alpha-induced p53 is transcript

43 donor that delivers this gas selectively to hypoxic cells.

44 ukaryotic multicellular organisms coordinate hypoxic cellular responses in a spatiotemporal manner.

45 Organoids were cultured in hypoxic chamber with 0.1% O(2) for 24 hours.

46 The data show that pravastatin protected the hypoxic chicken embryo against impaired cardiovascular d

47 e show that the treatment of the chronically hypoxic chicken embryo with pravastatin from day 13 of i

48 chanisms on the cardiovascular system of the hypoxic chicken embryo, a model system that permits the

49 eptors in the placental labyrinthine zone in hypoxic compared to normoxic dams.

50 Organoids cultured under this hypoxic condition showed increased permeability, pro-inf

51 In contrast, under a hypoxic condition, AR could increase miR-185-5p expressi

52 s in neuroblastoma cells was increased under hypoxic conditions and following hypoxia-inducible facto

53 ible factor (HIF), which is stabilized under hypoxic conditions and mediates IEC homeostatic response

54 lop embedded in a low-oxygen niche, and that hypoxic conditions are required to regulate the producti

55 n enhanced cell-killing effect is seen under hypoxic conditions both in vitro and in vivo.

56 operties, may protect the fetal growth under hypoxic conditions by improving uteroplacental perfusion

57 s to altered cellular metabolic pathways and hypoxic conditions during fetal development; this stress

58 ajor roles of physiological and pathological hypoxic conditions in the maintenance of intestinal home

59 ion endometrial stromal cells are exposed to hypoxic conditions in vitro, we observed a striking enha

60 sex similarities are maintained under acute hypoxic conditions is unknown.

61 on several meningioma cell lines cultured in hypoxic conditions validated the association of CA9 and

62 oglobin-O(2) binding affinity of sea bass in hypoxic conditions with ambient (~650 muatm) or raised C

63 agricultural soils especially when flooding (hypoxic conditions) results from over irrigation or freq

64 th low light fluence under both normoxic and hypoxic conditions, after activation by intracellular GS

65 from pyruvate to acetate is activated under hypoxic conditions, and ACS recovers carbon that would o

66 ced by EndMT-promoting, proinflammatory, and hypoxic conditions, and supports the acquirement of a me

67 Under hypoxic conditions, but in the presence of normal convec

68 formation and activity under both basal and hypoxic conditions, emphasising the importance of glycol

69 associated with hypertension in humans under hypoxic conditions, shows a previously undocumented role

70 In hypoxic conditions, the HIF activation regulates the exp

71 veloping oocytes through vitellogenins under hypoxic conditions, thereby increasing survival rates of

72 ine model of fetal development under chronic hypoxic conditions, we identify iFHRV in isolated fetal

73 fected glucose uptake and bone resorption in hypoxic conditions.

74 ifferent breast cancer cell lines exposed to hypoxic conditions.

75 on of the EGFR HRE prevented induction under hypoxic conditions.

76 atigue after inspiratory loading under acute hypoxic conditions.

77 ss roots of chickpea seedlings in aerated or hypoxic conditions.

78 type I IFN pathway were downregulated under hypoxic conditions.

79 n diaphragm fatigability persist under acute hypoxic conditions.

80 to promote the survival of the species under hypoxic conditions.

81 Importantly, IFN secretion was reduced under hypoxic conditions.

82 ry cycle, including active expiration, under hypoxic conditions.

83 PDT outcomes should be achievable even under hypoxic conditions.

84 atory cytokine levels in the organoids under hypoxic conditions.

85 ncrease in bone resorption that occurs under hypoxic conditions.

86 ith NFKB2 expression and its induction under hypoxic conditions.

87 ngly, loss of PQM-1 increases survival under hypoxic conditions.

88 Deceased donor kidneys are preserved in cold hypoxic conditions.

89 ) in live mammalian cells under normoxic and hypoxic conditions.

90 ced by EndMT-promoting, proinflammatory, and hypoxic conditions.

91 d transcriptional activity under normoxic or hypoxic conditions.

92 y ionization (DESI)-MSI defined regions of a hypoxic core and a proliferative outer layer from metabo

93 ascular cylinder; the extent of the severely hypoxic core increased as external O(2) was reduced.

94 neural cells to physiological and pathologic hypoxic cues.

95 Hypoxic damage to the developing brain due to preterm bi

96 hods: Thirty consecutive patients with acute hypoxic de novo respiratory failure admitted to a single

97 echanical ventilation (NIV) failure in acute hypoxic de novo respiratory failure.Objectives: To explo

98 The conservation of hypoxic drug-resistant niches in bacterial and fungal bi

99 tigate the early transcriptional programs of hypoxic ECs by using RNA-Seq of primary cultured human u

100 in and periphery, it is widely accepted that hypoxic effects of opioids result solely from their dire

101 pecific complications of severe disease (eg, hypoxic encephalopathy and critical care neuropathy) fro

102 In this unique, closed, and hypoxic environment close to the endosteal surface and a

103 The hypoxic environment in the spheroid cultures recruited m

104 , the microbiome initiates and maintains the hypoxic environment of the intestine that is critical fo

105 ngs rapidly transition from a pathogen-free, hypoxic environment to a pathogen-rich, rhythmically dis

106 a breast adenocarcinoma cell line (MCF7) in hypoxic environment.

107 hese processes of early pregnancy occur in a hypoxic environment.

108 a and is known to promote cell survival in a hypoxic environment.

109 is process is perturbed in cancer cells in a hypoxic environment.

110 portance of mitochondrial plasticity in cold hypoxic environments remains unresolved.

111 the deepest hypoxia and instead are found in hypoxic environments similar to those of MPPs.

112 otes, a few unicellular lineages, growing in hypoxic environments, have secondarily lost this ability

113 rates of thermogenesis to cope with cold and hypoxic environments.

114 ormation, NO production apparently regulates hypoxic ethylene biosynthesis.

115 mbination, indicating that even a short-term hypoxic event may weaken the ability of marine invertebr

116 laboratory or the field following a natural hypoxic event.

117 s and an elevated frequency and intensity of hypoxic events in the coastal zone, which have the poten

118 our results suggest that local reduction of hypoxic events may mitigate the impacts of global climat

119 o worsening of pulmonary gas exchange during hypoxic exercise but had greater lactate and lower pH th

120 w their altered haemoglobin affinity impacts hypoxic exercise tolerance.

121 ygen gradient significantly increased during hypoxic exercise, whereas pulmonary gas exchange in HAH

122 reserves pulmonary gas exchange during acute hypoxic exercise.

123 with appropriate interventions could reduce hypoxic exposure and consequently reduce the risk of com

124 Results suggest that hypoxic exposure induces immunosuppression which could i

125 ct ventilation, nor the acute HVR (10-15 min hypoxic exposure).

126 le Nkx2-5(+/-) embryos died within 2 days of hypoxic exposure.

127 PQM-1 promotes hypoxic fat metabolism by maintaining the expression of

128 ample cardiac reserves, as heart rate during hypoxic flights was not higher than in normoxic flights.

129 quaternary state modulates O(2) delivery to hypoxic (FME) and normoxic (LOX) human melanoma xenograf

130 The system was based on recording the hypoxic function of cancer tumors by Multi-wall carbon n

131 o orchestrate a coordinated inflammatory and hypoxic gene program to mount an effective immune respon

132 olling oxygen consumption rates, suppressing hypoxic glycogen levels, and inhibiting the expression o

133 ter two mirroring in part the development of hypoxic granulomas in human disease progression.

134 s, when compared to the normoxic control and hypoxic group with daily acute intermittent hypoxia (dAI

135 , which in turn reduces energetic needs in a hypoxic habitat.

136 irmed activation of proangiogenic factors in hypoxic HSC.

137 strate that increased purinosome assembly in hypoxic human cells requires the activation of hypoxia i

138 pable of both aerobic (oxygen producing) and hypoxic (hydrogen producing) photosynthesis in daylight

139 ing oligodendrocytes, sublethal intermittent hypoxic (IH) stress activated cyclophilin D-dependent mi

140 4 isoform 2] in Complex IV) had no effect on hypoxic increases in [Ca(2+)](i).

141 uman umbilical vein endothelial cells into a hypoxic incubator (1% O2) for 24 hours, with reoxygenati

142 y smooth muscle cells (HPASMCs) demonstrated hypoxic induction of Hyal2 and SOD-suppressible hyaluron

143 Knockdown or knockout of NICI attenuated hypoxic induction of SLC2A3, indicating a direct regulat

144 Hyaluronan fragmentation corresponded to hypoxic induction of the cell surface hyaluronidase-2 (H

145 ll intestine of treated animals show reduced hypoxic injury compared to controls and the kidneys have

146 , but with neurological deficits, suggesting hypoxic injury in survivors.

147 t this mechanism is important in attenuating hypoxic injury.

148 s of prematurity classically associated with hypoxic insults.

149 Toxic, inflammatory, or hypoxic-insults to RTECs can cause systemic fluid imbala

150 lasmic sentinels are arranged along normoxic/hypoxic interfaces in OHM2.

151 of mechanical ventilation and risk of death, hypoxic ischaemic encephalopathy or respiratory arrest d

152 (HT) is standard care for term infants with hypoxic-ischaemic (HI) encephalopathy.

153 tial for modelling neural insults, including hypoxic-ischaemic and Ca(2+)-dependent injury.

154 peutic effects of hUCBCs in a mouse model of hypoxic-ischaemic brain injury (HI).

155 Hypoxic-ischaemic encephalopathy (HIE) affects 2-4/1000

156 Neonatal hypoxic-ischaemic encephalopathy (HIE) is a leading caus

157 In patients at risk of hypoxic ischemic brain injury following cardiac arrest,

158 f mechanical ventilation, and risk of death, hypoxic ischemic encephalopathy or respiratory arrest.

159 more ischemic stroke (10% vs 1%; p < 0.001), hypoxic-ischemic brain injury (13% vs 1%; p < 0.001), an

160 The most common acute brain injury was hypoxic-ischemic brain injury (44%), followed by intracr

161 ver, ischemic stroke (10% vs 1%; p < 0.001), hypoxic-ischemic brain injury (7% vs 1%; p = 0.02), and

162 Patients with hypoxic-ischemic brain injury had more hypertension (8 v

163 esence of diffusion limitation physiology in hypoxic-ischemic brain injury patients with brain hypoxi

164 In hypoxic-ischemic brain injury patients with brain hypoxi

165 The most common involved location for hypoxic-ischemic brain injury was cerebral cortices (82%

166 Hypoxic-ischemic brain injury was the most common type o

167 logic complication, 23% (95% CI, 0.14-0.32%) hypoxic-ischemic brain injury, 6% (95% CI, 0.02-0.11%) i

168 y resuscitation and the most common type was hypoxic-ischemic brain injury.

169 dmission to the NICU with moderate-to-severe hypoxic-ischemic encephalopathy at day 1 to 5 during hos

170 ive care unit (NICU) with moderate-to-severe hypoxic-ischemic encephalopathy at day 1 to 5 during hos

171 ational guidelines (adult cardiac arrest and hypoxic-ischemic encephalopathy of newborns) or intraope

172 ational guidelines (adult cardiac arrest and hypoxic-ischemic encephalopathy of newborns).

173 Neuroprognostic approaches to hypoxic-ischemic encephalopathy vary among physicians an

174 early neonatal death and moderate-to-severe hypoxic-ischemic encephalopathy.

175 2)-IV(1) and III(2)-IV(2) SCs containing the hypoxic isoform Cox5B solved at 3.4 and 2.8 angstrom, re

176 en species, phototoxicity within the deeper, hypoxic layers of the spheroids was also investigated.

177 f P2RX7 immediately after injury, indicating hypoxic like damage and endothelial cell growth and prol

178 For all studied species, thermal and hypoxic limits are substantially reduced by the energeti

179 w small extracellular vesicles released from hypoxic mammary tumor cells facilitate intercellular com

180 s that alter nitrate supply affect levels of hypoxic metabolites, nectar volume and nectar sugar comp

181 e uterine artery was increased with AICAR in hypoxic mice (P < 0.001), suggesting that the vasodilato

182 ize, we recapitulated the tumor size-induced hypoxic microenvironment and emergence of migratory phen

183 ntrast, inflammatory Th17 cells experience a hypoxic microenvironment known to limit mitochondrial re

184 Regions of tumor heterogeneity and the hypoxic microenvironment were observed based on the spat

185 agen secretion may be intimately linked to a hypoxic microenvironment within keloid tumors and that H

186 Cancer cells respond to hypoxic microenvironments by activating the transcriptio

187 We observe that these self-induced hypoxic microenvironments not only contribute to filamen

188 In the hypoxic mitochondrion, cytochrome c oxidase, which is a

189 t gene expression, althought it did induce a hypoxic molecular response in the brain.

190 Because of the hypoxic nature of solid tumors, we investigated if oxyge

191 the pseudopalisading cells that envelop the hypoxic-necrotic regions, and mitochondrial NIX expressi

192 to resistance to MCT1 inhibitor treatment in hypoxic neuroblastoma tumors.

193 Our findings indicate that hypoxic niches are poised to accumulate CSCs in a molecu

194 easurements were repeated under normoxic and hypoxic (normobaric (NH) and hypobaric (HH)) conditions,

195 aining cellular homeostasis helps to nourish hypoxic, nutrient-starved tumors and protects them from

196 Although hypoxic or ischemia tolerance in AGS involves physiologi

197 unger than 2 years as severe or very severe, hypoxic, or radiological pneumonia as per WHO definition

198 ial fission enhanced the CDDP sensitivity of hypoxic ovarian cancer cells.

199 vival under environmental conditions such as hypoxic, oxidative, and nitrosative stress found at site

200 Functional examination of hypoxic pASCs demonstrated acquisition of contractile ab

201 processes in the initiation of experimental hypoxic PH and can serve as a prognostic biomarker of ou

202 processes in the initiation of experimental hypoxic PH and demonstrates complement signaling as a cr

203 Fhit(-/-) mice had exaggerated hypoxic PH and failed to recover in normoxia.

204 In experimental hypoxic PH, proinflammatory and pro-proliferative respon

205 tes characteristics of BBB dysfunction under hypoxic physiological conditions and when exposed to exo

206 re or very severe pneumonia, 46% (33-56) for hypoxic pneumonia, and 25% (9-38) for radiological pneum

207 pneumonia, severe or very severe pneumonia, hypoxic pneumonia, and radiological pneumonia.

208 Hypoxic preconditioning reduces disease severity in a mo

209 While several studies have shown that hypoxic preconditioning suppresses development of the ex

210 protocols, including caloric restriction and hypoxic preconditioning, have been shown to prevent inju

211 rlapping patterns in caloric restriction and hypoxic preconditioning, pointing toward common molecula

212 d pathways shared by caloric restriction and hypoxic preconditioning, we used RNA-sequencing transcri

213 Isolated fetal hearts from hypoxic pregnancy exhibit a time scale-dependent higher

214 Maternal vitamin C in hypoxic pregnancy improved transplacental oxygenation an

215 Hearts of fetuses isolated from hypoxic pregnancy showed approximately 4-fold increases

216 rts and show that it is markedly affected by hypoxic pregnancy.

217 These RBPs collaborate with the hypoxic protein synthesis apparatus, operating as a tran

218 Iron deficiency augments hypoxic pulmonary arterial pressure in healthy individua

219 oxical findings may be explained by impaired hypoxic pulmonary vasoconstriction in infected lung regi

220 ortion of the tumour which is proliferating, hypoxic/quiescent and necrotic/nutrient-deficient).

221 sease without altering life-saving autonomic hypoxic reflexes.

222 served throughout their depth, including the hypoxic region.

223 a complex tissue with multiple heterogeneous hypoxic regions and significant cell-to-cell variability

224 VRN2 localizes to endogenous hypoxic regions in aerial and root tissues.

225 aggressive HNSCC is the presence of severely hypoxic regions in tumors and activation of hypoxia-indu

226 ze toward the outer proliferative or central hypoxic regions of an MTS.

227 tion also drove oligodendrocyte formation in hypoxic regions of human oligocortical spheroids.

228 f [Formula: see text] exchanges in the inner hypoxic regions where tumor cells are known to acquire m

229 Hypoxic regions within tumors represent sources of aggre

230 pair of an aortic dissection, complicated by hypoxic respiratory failure and oliguric renal failure.

231 She quickly progressed to acute hypoxic respiratory failure and vasoplegic shock.

232 Based on preliminary clinical reports, hypoxic respiratory failure complicated by acute respira

233 piratory failure can be managed similarly to hypoxic respiratory failure of other etiologies.

234 practices for supportive management of acute hypoxic respiratory failure.

235 ty of transcriptional regulators involved in hypoxic response (Hif1a) and emergency granulopoiesis (C

236 m network of EPAS1, elucidating its roles in hypoxic response and angiogenesis.

237 ed us to examine the interaction between the hypoxic response and the circadian clock in vivo.

238 uncovered that KLF6 govern inflammatory and hypoxic response by regulating HIF1alpha expression in m

239 hage functions by promoting inflammatory and hypoxic response gene programming.

240 uncovered the molecular underpinnings of the hypoxic response in ECs; however, there is a need for co

241 hromatin modifications, DNA methylation, the hypoxic response, and immunity.

242 actase persistence, to skin pigmentation, to hypoxic response, to arsenic tolerance.

243 velopment of a chemical understanding of the hypoxic response.

244 may partly explain the heterogeneity in the hypoxic response.

245 ic deletion of Cox4i2 mimicked the defective hypoxic responses of Epas1-null mice.

246 in GBM stemness and tumor progression, where hypoxic responses within the tumor inhibit MBNL1 activit

247 ntrols a unique but overlapping portfolio of hypoxic responsive proteins.

248 In the CIV(5B)-containing hypoxic SCs, this could be confidently assigned to the h

249 , these suppressor mutations restored normal hypoxic sensitivity and protein synthesis to the tRNA bi

250 inflammatory diseases are similar: both are hypoxic, show elevated levels of lactate and other metab

251 sttranscriptional safeguard against aberrant hypoxic signaling and abnormal cell-cycle progression.

252 The selective activation of hypoxic signaling by metastatic breast cancer in the bra

253 mors, and in patients with brain metastases, hypoxic signaling within CTCs predicts decreased overall

254 effective way to reduce N(2)O emission from hypoxic soil in agricultural production systems.

255 rence and sequelae of disorders that lead to hypoxic spells such as asthma, chronic obstructive pulmo

256 armacology studies to precisely document the hypoxic status of tumors both before and during the time

257 titative measures of tissue hemodynamics and hypoxic status.

258 -4 along with hemocyte counts, biomarkers of hypoxic stress and immune health, respectively, were mea

259 Hypoxic stress and the associated energy crisis activate

260 developed various adaptations in response to hypoxic stress and these have been described extensively

261 Thermal and hypoxic stress commonly coexist in environmental, occupa

262 t impaired by any combination of thermal and hypoxic stress despite large reductions in CDO(2) Chroni

263 enhances monocyte removal by amplifying the hypoxic stress manifest within monocytes in acute inflam

264 scription factor PQM-1 as a regulator of the hypoxic stress response.

265 een for mutations protecting C. elegans from hypoxic stress, we isolated multiple genes impacting pro

266 iron, regulating the similar pathways during hypoxic stress.

267 ral inputs into fine-tuning the responses to hypoxic stress.

268 (DDR) pathway activated during metabolic and hypoxic stress.

269 nsion, enlarged hearts, cellular energy, and hypoxic stress.

270 tly associated with the magnitude of a brief hypoxic stress.

271 o-resistant tumours such as those containing hypoxic subregions.

272 In conclusion, our capsules can prevent hypoxic tissue damage.

273 nthesis machinery ('Jekyll') and activates a hypoxic translational architecture ('Hyde') to drive tra

274 r METTL3-mediated m(6) A modification in the hypoxic tumor microenvironment and identifies FOXO3 as a

275 nd HIF-2alpha, regulates TEM function in the hypoxic tumor microenvironment.

276 which can then release (1) O(2) in the dark, hypoxic tumor microenvironment.

277 of miRNAs in different environments such as hypoxic tumor microenvironments.

278 tate PolyhHb, which led to no improvement in hypoxic tumors and significantly worsened outcomes in no

279 on-specific manner, suggesting patients with hypoxic tumors may benefit from EGFR inhibitors already

280 This limits the utility of PDT in treating hypoxic tumors since lower levels of cytotoxic reactive

281 In treatment of hypoxic tumors, oxygen-dependent photodynamic therapy (P

282 ich could contribute to immunosuppression in hypoxic tumors.

283 affinity HBOCs would perform in normoxic and hypoxic tumors.

284 mor growth, and decreased vascularization in hypoxic tumors.

285 ow levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy.

286 PR) imaging shows the validation of treating hypoxic tumours with a threshold of PO2 <= 10 Torr, and

287 ations in TP53, MYC and PTEN are enriched in hypoxic tumours, and mutations in PTEN interact with hyp

288 scription factors that are key regulators of hypoxic vascular responses.

289 del of Perutz, to blood flow autoregulation (hypoxic vasodilation governing oxygen delivery) observed

290 Notably, hypoxic vasodilation is recapitulated by native S-nitros

291 for caution in patients who are dependent on hypoxic ventilatory drive.

292 ent increase in baseline ventilation and the hypoxic ventilatory response (HVR) occurring over days t

293 dent increase of resting ventilation and the hypoxic ventilatory response (HVR) that is called ventil

294 cell responsiveness to acute hypoxia and the hypoxic ventilatory response.

295 Since the MM microenvironment is hypoxic, we assessed if hypoxia and/or interactions with

296 e dehydrogenase activity increased by 71% in hypoxic WT but not Ppara(-/-) mice.

297 lly explicit, time-evolving forecasts of the hypoxic zone that combines statistical forecasting with

298 control is needed to avoid expansion of the hypoxic zones in that specific region.

299 vivo, high CCL-2 production was detected on hypoxic zones of melanoma tumors (where tryptase-positiv

300 show that MCs are located preferentially in hypoxic zones of melanoma tumors, hypoxia-induced CCL-2