ライフサイエンスコーパス: imino

1 or several nucleotides by 1-dimensional (1D) imino (1)H NMR as well as by 2D HyperW NMR spectra acqui

2 Observation of imino (1)H resonances is an established method for evalu

3 er conditions used in this study, we observe imino (1)H signals in MN19 not previously seen, which le

4 at 3 (MK-8931), a diaryl amide-substituted 3-imino-1,2,4-thiadiazinane 1,1-dioxide derivative, is a h

5 synthesis of N-fused and 3,4-disubstituted 5-imino-1,2,4-thiadiazole derivatives has been achieved th

6 Overall, 5-imino-1,2,4-thiadiazoles are presented here as new molec

7 Here, we report substituted 5-imino-1,2,4-thiadiazoles as the first small molecules ab

8 for the preparation of 1-(N-ribofuranosyl)-6-imino-1,6-dihydropyrimidin-4-amines 3 or 4-(N-ribofurano

9 d, but the n = 3 ring hydrolyzes to form a 3-imino-1-oxoisoindoline derivatized crown ether species.

10 ,9-dihydro-2H-purin-2,6-diamines 21-24 and 6-imino-1-phenyl-8,9-disubstituted-6,9-dihydro-1H-purin-2-

11 he bimetallic 2,7-di-[(2,6-diisopropylphenyl)imino]-1,8-naphthalenediolato group 10 metal polymerizat

12 minoanthrone, 9-imino-10-silaxanthone, and 9-imino-10-germaxanthone fluorophores.

13 nm Stokes shifts based on 9-iminoanthrone, 9-imino-10-silaxanthone, and 9-imino-10-germaxanthone fluo

14 ethylphenyl)amino)-4-((2,6-diisopropylphenyl)imino)-2-pentene) , for the controlled ROP of various OC

15 opylphenyl)amido)-4-((2,6-diisopropylphenyl)-imino)-2-pentene], chemo- and regioselective polymerizat

16 aneously rearranges in the dark to singlet 6-imino-2,4-cyclohexadien-1-ketene on the time scale of se

17 5-exodig cyclization to give the 2-[1-aryl-5-imino-2-phenyl-1H-imidazol-4(5H)-ylidene]malononitriles

18 A lead compound in the series, JMS-053 (7-imino-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione), h

19 dium(II) carbenoid, leading to a transient 1-imino-2-vinylcyclopropane intermediate which rapidly und

20 with nitriles and alkynes, ring opening of 2-imino-2H-azirines, or direct metalation of 4-azadiene-1-

21 subunit blockers suramin (8,8'-[carbonylbis[imino-3,1-phenylen ecarbonylimino(4-methyl-3,1-phenylene

22 base (2 equiv) to give in one step 3-aryl-4-imino-3,4-dihydroquinazoline-2-carbonitriles in 53-81% y

23 cular C-N cyclization of 3-(2-bromophenyl)-4-imino-3,4-dihydroquinazoline-2-carbonitriles.

24 0.008, using bath-applied 200 nm SR 95531 [6-Imino-3-(4-methoxyphenyl)-1(6H)-p yridazinebutanoic acid

25 with the single-crystal X-ray structure of 4-imino-3-phenyl-3,4-dihydroquinazoline-2-carbonitrile.

26 NF279 (8,8'-[carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylim

27 ydrogenative coupling reactions of 1-amino-2-imino-4-arylpyridine-3-carbonitriles with benzocyclic ke

28 tes that Cu(2+) catalyzes the formation of 6-imino-5,6-dihydropyrrolo[3,4- d]imidazole-4(3 H)-one (IP

29 een and identified a tris-aryl substituted 2-imino-5-arylidenethiazolidin-4-one, compound 1, as an in

30 -LTQ-Orbitrap MS and NMR as N-(4-carbamoyl-2-imino-5-oxoimidazolidin)formamido-N-methoxyacetic acid (

31 H 8 led to the formation of the respective 2-imino-5-oxoimidazolidines, confirming that guanine deriv

32 -disubstituted-9H-purin-6-amines 27-31 and 6-imino-8,9-disubstituted-6,9-dihydro-1H-purin-1-amines 32

33 in redox behavior of the monofunctional bis(imino)acenaphthene (BIAN) and bifunctional tetrakis(imin

34 ed functionalization of the redox-active bis(imino)acenaphthene (BIAN) ligand class has been explored

35 Furthermore, the structure reveals that the imino acetamido group of TK40 acts as an alpha-amino aci

36 disulfanyl]-2-[(1,3-dimethyl-1H-pyrazol-5-yl)imino]acetonitr ile (8a) gave 4,6,10,12-tetramethyl-6H-p

37 iethylamino)disulfan-yl]-2-[(1H-pyrazol-5-yl)imino]acetonitrile (8a).

38 ht serve in relaying a H(+) from the product imino acid =NH(2)(+) group bound on the flavin Re-side t

39 gnetic resonance was used to assign the free imino acid as (3S,5S)-5-chloropiperazate, distinct from

40 ro-tRNAPhe and Phe-tRNAPro, we show that the imino acid proline and not tRNAPro imposes the primary e

41 The imino acid proline is a poor donor and acceptor for pept

42 tide bond synthesis by most amino acids, the imino acid proline is a poor substrate for protein synth

43 and structural characterization of Bsp5, an imino acid reductase from the d-2-hydroxyacid dehydrogen

44 xidase partner, suggesting that this oxidase-imino acid reductase pair could be evolved for biocataly

45 Since collagen has a high content of imino acid residues, the cumulative effects of cis-trans

46 ts 10/3 superhelical properties, whereas the imino acid rich N- and C-terminal regions adhere to a 7/

47 The non-canonical imino acid, (2S,4S)-4-aminoproline (amp), was used to sp

48 ace of collagen molecules, it is likely that imino acid-aromatic CH...pi interactions are important i

49 1032) structure reveals that the central non-imino acid-containing region adopts 10/3 superhelical pr

50 Fine tuning of a previously reported imino-acid directing group and using the ligand combinat

51 In vitro, both proteins hydrolyzed 2-imino acids (IA) to keto-acids and ammonia.

52 ically pre-treated bone gelatines had higher imino acids (proline and hydroxyproline) contents compar

53 ntained glycine as the major amino acid with imino acids (proline and hydroxyproline) of 194-195 resi

54 id dehydrogenase family that reduces acyclic imino acids produced in situ by a partner oxidase.

55 interaction between aromatic amino acids and imino acids within the triple helix is also supported by

56 d profile of BSG showed a high percentage of imino acids.

57 and other D-amino acids to the corresponding imino acids.

58 always flanked by a specific distribution of imino acids.

59 xylamine O-vinyl ethers and imino ketones or imino aldehydes along the reaction pathway were determin

60 N,O-divinyl hydroxylamines to corresponding imino-aldehydes (Paal-Knorr intermediates) revealed that

61 The absolute configuration of the imino-aldol adducts has been determined.

62 to high ee has been developed via asymmetric imino-aldol and aldol reactions, respectively, starting

63 approach involving asymmetric Mannich-type (imino-aldol) reactions of methyl phenylacetate with N-te

64 u, Ni, Co, Fe, Mn, Cr) with 2 equiv of alpha-imino alkoxide salts K(RR'COCNtBu) (R = Me, tBu; R' = iP

65 diastereo- and enantiocontrol, forming beta-imino amides that can be deprotected to the primary beta

66 he close proximity between the intra-residue imino and amino protons.

67 A range of biologically significant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol,

68 by the ATP synthase inhibitor AMP-PNP (gamma-imino ATP, a nonhydrolyzable ATP analog) and Mg(2+)/ADP.

69 thiol oxidants and inhibited by Mg(2+)/gamma-imino ATP.

70 m Ala, Phe, or hPhe gave the hydrates of the imino beta-keto-alpha,alpha-difluorosulfonamides.

71 The alpha-(N-hydroxy/aryl)imino-beta-oxodithioesters are readily accessible by the

72 ] heterocyclization of alpha-(N-hydroxy/aryl)imino-beta-oxodithioesters with in situ generated Cu-car

73 ed transporter protein, DHSA, is fused with (imino)biotinylated cargo proteins via an avidin adaptor

74 mine with ethyl diazoacetate mediated by the imino-BOROX catalyst to give aziridine-2-carboxylic este

75 aldehyde and the concomitant formation of an imino-BOROX chiral Bronsted acid and finally the reactio

76 Two new C-nucleoside analogues, BCX4430, an imino-C-nucleoside, and GS-6620, a phosphoramidate deriv

77 precursors for the formation of metal-bound imino carbene intermediates.

78 n achieved by reaction of rhodium-stabilized imino-carbenes with furans.

79 energy barrier to transfer a proton between imino centers in [II-H](+) is 1 order of magnitude lower

80 beta-carbon methylation to give the primary imino complex cis-[Re(PNP(tBu)-HN horizontal lineCC(Me)P

81 Betalamic acid condenses with imino compounds (cyclo-DOPA or its glucosyl derivatives)

82 cant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol, 3,6-dideoxy-3,6-imino-L-allonic acid, (

83 e to aldehyde derivatives of 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) and its enantiomer (LAB) and su

84 nd GP were both inhibited by 1,4-dideoxy-1,4-imino-d-arabinitol, but only GP was inhibited by isofago

85 d 2,5-dideoxy-3-O-alpha-d-glucopyranosyl-2,5-imino-d-mannitol (9) to act as an inhibitor of GlgE.

86 h 2,5-dideoxy-3-O-alpha-D-glucopyranosyl-2,5-imino-D-mannitol (DDGIM), an oxocarbenium mimic, was sol

87 e; alpha-homonojirimycin and 2,5-dideoxy-2,5-imino-d-mannitol were the major iminosugars determined.

88 this regard, we show here that deshydroxy-1-imino derivatives of acridine (i.e., dihydroacridinedion

89 etin glycopentoside, XXI.4,4'-dihydroxy-3,3'-imino-di-benzoic acid, XXV.quercetin-3-O-rhamnogalactosi

90 - and monozinc catalysts, coordinated by bis(imino)diphenylamido ligands, show remarkable activities

91 another nitrogen containing intermediate, 4-imino-DMQ(6).

92 ation, aza-Henry, aza-Morita-Baylis-Hillman, imino-ene, Mannich-type, and cycloaddition reactions, as

93 3+2] cycloaddition of methyl acrylate and an imino ester prepared from l-leucine t-butyl ester hydroc

94 c compounds to the N-perfluorobutanesulfinyl imino ester provided arylglycines with very high diaster

95 of alpha-chloroglycine ester as a practical imino ester surrogate.

96 The utility of this activated N-sulfinyl imino ester was demonstrated for reactions that gave eit

97 ylate provided the N-perfluorobutanesulfinyl imino ester.

98 s various functional groups, including keto, imino, ester, ether, and cyano.

99 oselective 1,3-dipolar cycloaddition between imino esters and electrophilic alkenes, employing chiral

100 talyzed Povarov-type reaction of fluorinated imino esters and furans is described.

101 alyzed 1,3-dipolar cycloaddition (1,3-DC) of imino esters and nitroalkenes, with alpha,beta-unsaturat

102 , and applications of the reactions of alpha-imino esters and related compounds in organic synthesis,

103 Due to the adjacent ester group, alpha-imino esters are more reactive relative to other types o

104 alpha-Imino esters are useful precursors for the synthesis of

105 alyzed the reactions of aldehydes with alpha-imino esters under mild conditions and afforded anti-Man

106 For the reactions of ketones with alpha-imino esters, (R)-3-pyrrolidinecarboxylic acid was an ef

107 E)-tert-butyl 6-bromo-2-hexenoate with alpha-imino esters.

108 istical copolymerization of these two cyclic imino ether monomers has not yet been reported.

109 he active site, suggesting that it is the N6-imino form of cADPR that is hydrolyzed by CD38.

110 The expected enol-imino form, in which the enol is part of a phenyl system

111 60% of neutral KP1212 is present in the enol-imino form.

112 tautomerism of the amino derivatives to the imino forms likely accounts for their loss in biological

113 midazolin-2-imino group is an N-heterocyclic imino functionality that derives from the class of compo

114 lide (23 new examples in 45-85% yield) or by imino group formation from the corresponding beta-keto s

115 Thus, this imino group is an excellent choice for thermodynamic sta

116 The imidazolin-2-imino group is an N-heterocyclic imino functionality tha

117 rectly measure pK(a) values for the Ade38 N1 imino group of a hairpin ribozyme in distinct conformati

118 In aprotic solvent, the imino group that forms ortho to the boronic acid or boro

119 of methyl phenyldiazoacetates with an ortho-imino group, prepared from o-aminophenylacetic acid, to

120 ddition, we showed that carboxyl, amino, and imino groups are nearly equally distributed over beta-sh

121 c acids and proteins where amide, amino, and imino groups are rapidly moving between a closed solvent

122 s generated by the reductive coupling of the imino groups of three salophen ligands, resulting in thr

123 s of Phe and of positively charged amino and imino groups remain similar.

124 impact of protium-deuterium exchange of the imino hydrogen on the free energy of RNA basepair openin

125 The yield of the imino hydroxylamine increases at the expense of the imin

126 ually converting C-PTIO to the corresponding imino hydroxylamine, C-PTI-H.

127 ventually converted into imino nitroxide and imino hydroxylamine.

128 via comproportionation with the nitronyl and imino hydroxylamines.

129 A new class of highly acidic confined imino-imidodiphosphate (iIDP) Bronsted acids catalyze th

130 kene aminocarbonylation pathway involving an imino-isocyanate intermediate is proposed and supported

131 r [1,4] H atom shift from the nitrene to the imino ketene occurs by tunneling, on the triplet manifol

132 state opens the structural study of the enol-imino-keto-enamine forms and the influence of the interm

133 of N-alkenylhydroxylamine O-vinyl ethers and imino ketones or imino aldehydes along the reaction path

134 dideoxy-1,4-imino-D-allitol, 3,6-dideoxy-3,6-imino-L-allonic acid, (3R,4S)-3,4-dihydroxy-L-proline, 1

135 The iminosugar 1,4-dideoxy-1, 4-imino-l-arabinitol (LAB) inhibits arabinoxylan arabinofu

136 enzonitriles, and aryl halides produces beta-imino lactams that then afford beta-keto lactams by acid

137 me as potential precursors to generate alpha-imino metal-carbene intermediates and applied in direct

138 2,6-bis(((4-(1H-benzo[d]imidazol-2-yl)phenyl)imino) methyl)-4 methyl phenol]) could sense PPi anion t

139 , 3,3-bis(4-hydroxy-3-((E)-((4-hydroxyphenyl)imino)methyl) phenyl)isobenzofuran-1(3H)-one (HMBP) was

140 The Zn-Hbimcp (Hbimcp = 2,6-bis((imino)methyl)-4-chlorophenol) coordination bond used in

141 igand 2-[[(3,5-di-tert-butyl-2-hydroxyphenyl)imino]methyl]-4,6-di-tert-butylphenol 1.

142 ounds, 2,4-dichloro-6-{(E)-[(3-methoxyphenyl)imino]methyl}phenol (DPMP).

143 results demonstrate the essentiality of the imino moiety as well as the importance of its interactio

144 copy to measure directly the pK(a) of the N1-imino moiety in the context of hairpin ribozyme crystals

145 We propose that the imino moiety of A9 promotes a key water-mediated contact

146 investigate these residues, we replaced the imino moiety of each base with N1-deazaadenosine.

147 vorable TS interaction energy (Munchnones or imino-Munchnones) or the smallest TS distortion energy (

148 itions of mesoionic 1,3-dipoles (Munchnones, imino-Munchnones, and phospha-Munchnones) with alkynes o

149 eveloped an empirical relation that predicts imino N-H vector orientations from the heavy-atom coordi

150 calculations indicate that deviations of the imino N-H vectors in RNA U and G bases result from H-bon

151 k for the future development of asymmetric 2-imino-Nazarov cyclizations.

152 and revealed the pi-donating N-heterocyclic imino (NHI) and sigma-donating silyl groups as key facto

153 hilic attack of the carbene lone pair on the imino nitrogen (pathway "a") or on the carbon atom in th

154 " process is triggered by protonation of the imino nitrogen and concomitant conformational change of

155 number of catenated methylene units between imino nitrogen atoms).

156 es advantage of the strong dependence of the imino nitrogen chemical shift on hydrogen bonding and in

157 ding some of the Mg(2+) assignments near the imino nitrogen of guanine, is suggestive of the existenc

158 ith the pyridine nitrogen of the PLP and the imino nitrogen of the Schiff base, respectively.

159 lack of any detectable chemical exchange by imino nitrogen rotating frame spin relaxation (R1rho) ex

160 functional role of cytosine's keto group and imino nitrogen.

161 ith a methyl group as the substituent on the imino nitrogen.

162 ation dispersion for the hydrogen-bond donor imino nitrogens in G and T residues.

163 droxylamine and is eventually converted into imino nitroxide and imino hydroxylamine.

164 ydroxylamine increases at the expense of the imino nitroxide as the ratio [AS](0)/[nitronyl nitroxide

165 -PTIO to form (*)NO(2) and the corresponding imino nitroxide, C-PTI.

166 onyl nitroxide yields only the corresponding imino nitroxide, nitronyl nitroxide can discriminate NO

167 iophenes (BDTTh(2)) linked with nitronyl and imino nitroxides (NN and IN) as BDT-NN, BDT-IN, BDTTh(2)

168 , leading to the formation of the respective imino nitroxides and hydroxylamines via a complex mechan

169 (*)NO(2) oxidizes the nitronyl and imino nitroxides to their respective oxoammonium cations

170 ide (C-PTIO), which yields the corresponding imino nitroxides, is widely used for NO detection (mainl

171 The imino NMR spectra of pre-let-7 loops and LREs contain re

172 group(s) directly linked to a pulling cyano, imino, or phosphoimino group, as well as those in which

173 increases the basicity of the pulling cyano, imino, or phosphoimino group.

174 n the tautomeric equilibrium toward the rare imino-oxo tautomer of cytidine stabilizes the f(5)C34*A

175 using a non-natural substrate, benzaldehyde imino-oxy acetic acid (BIAA).

176 and Watson-Crick pairs are all head-to-head imino-paired (cis Watson-Crick/Watson-Crick).

177 n-Crick), with AG pairs that are only weakly imino-paired.

178 O-pentafluorobenzoyl oxime esters generates imino-Pd(II) intermediates, which undergo 5-exo cyclizat

179 The reaction of LGa (L = Dipp(4-(Dipp-imino)pent-2-en-2-yl)amide; Dipp: 2,6-diisopropylphenyl)

180 The N-substituted imino pharmacophore was therefore extended to fill the g

181 The triazole linked o-imino phenol appended calix[4]arene conjugate (L) has be

182 Four 4-[[(4-nitrophenyl)methylene]imino]phenols (2a-d) were synthesized.

183 The new chromophore, benzothiophene imino-phenylacetonitrile (BTIPA), was synthesized in fou

184 ation of styrenes by [ N-( p-toluenesulfonyl)imino]phenyliodinane (PhINTs).

185 4-methylthio-2-oxobutyric acid and 2-hydroxy-imino phenylpyruvic acid, both of which reduced polyposi

186 An imino-phosphanamide ligand, [NHI(iPr2Me2)P(Ph)NH-2,6-(i)

187 The ligand, imino-phosphanamidinate, [L](-), functions in a chelatin

188 rved ring expansion by insertion of a chloro(imino)phosphine into a P-N bond of the P-N-C-N framework

189 Increasing the pK(a) value of the imino proton by reduction of its 5,6-double bond results

190 r in the two structures are characterized by imino proton exchange and nuclear magnetic resonance spe

191 xternal catalysis exchange mechanisms on the imino proton exchange rates is analyzed.

192 characterizing the temperature dependence of imino proton exchange rates of individual basepairs.

193 nternal Psi-A, Psi-G and Psi-U pairs, the N3 imino proton is hydrogen bonded to the opposite strand n

194 NMR studies of imino proton lifetime, solvent accessibility, and NOE co

195 to the opposite strand nucleotide and the N1 imino proton may also be hydrogen bonded.

196 Imino proton NMR data provided evidence that elements of

197 The temperature-dependent imino proton NMR spectrum of oxoG modified DNA confirms

198 e versus temperature melting experiments and imino proton nuclear magnetic resonance (NMR).

199 The observed imino proton nuclear magnetic resonance resonances and F

200 The line width of the imino proton of the ClU residue is substantially greater

201 eased level of chemical exchange for the ClU imino proton of the ClU-A base pair, the ClU residue is

202 ding affinity was measured by monitoring RNA imino proton resonances for some of the compounds that s

203 lly greater than that of the corresponding T imino proton; however, this difference is not attributed

204 This is surprising, given that imino-proton exchange rates show that basepairs in a DNA

205 exchange cross peaks for several base-paired imino protons in the RNA yielded an apparent k(on) of 60

206 re the exchange rate constant (k(ex)) of the imino protons in the unbound, cocaine-bound, and quinine

207 ive imaging agents, since their exchangeable imino protons resonate at 5-6 ppm from the water proton

208 erized by measuring the rates of exchange of imino protons with solvent protons as a function of the

209 Psi has two hydrogen donors (N1 and N3 imino protons) and two hydrogen bond acceptors because t

210 cenaphthene (BIAN) and bifunctional tetrakis(imino)pyracene (TIP) ligands have been explored by treat

211 The bis(imino)pyridine 2,6-(2,6-iPr2-C6H3N=CPh)2-C5H3N ((iPr)BPD

212 Using just 1 mol % FeCl(2), bis(imino)pyridine 6 (1 mol %), CO(2) (atmospheric pressure)

213 explore the electronic structure of the bis(imino)pyridine alkyl-substituted imides.

214 blish competitive cyclometalation of the bis(imino)pyridine aryl substituents during catalytic turnov

215 are evaluated in the broader context of bis(imino)pyridine base metal chemistry and the influence of

216 de) = 1/2) and a closed-shell, dianionic bis(imino)pyridine chelate (S(PDI) = 0) is favored for the S

217 light the importance of the redox-active bis(imino)pyridine chelate for enabling catalytic cyclizatio

218 Fe(I)-Fe(III) catalytic cycle where the bis(imino)pyridine chelate remains in its one-electron reduc

219 l substituent into the 4-position of the bis(imino)pyridine chelate, enabling the facile hydroboratio

220 Pr)PDI)Mn, which features a pentadentate bis(imino)pyridine chelate.

221 o-electron reduction of the redox-active bis(imino)pyridine chelate.

222 (S(Fe) = 2) with neutral, redox-innocent bis(imino)pyridine chelates.

223 Planar S = (1/2) kappa(3)-bis(imino)pyridine cobalt alkene and tetrahedral kappa(2)-bi

224 nating functionality with a C1-symmetric bis(imino)pyridine cobalt catalyst is described and has been

225 Enantiopure C(1)-symmetric bis(imino)pyridine cobalt chloride, methyl, hydride, and cyc

226 e cobalt alkene and tetrahedral kappa(2)-bis(imino)pyridine cobalt diene complexes were observed by E

227 malgam reduction of the aryl-substituted bis(imino)pyridine cobalt dihalide complexes ((Ar)PDI)CoCl(2

228 series of cationic, neutral, and anionic bis(imino)pyridine cobalt dinitrogen compounds establish Co(

229 Aryl-substituted bis(imino)pyridine cobalt dinitrogen compounds, ((R)PDI)CoN2

230 The aryl-substituted bis(imino)pyridine cobalt methyl complex, ((Mes)PDI)CoCH3 ((

231 Bis(imino)pyridine cobalt methyl complexes are active for th

232 A bis(imino)pyridine cobalt-catalyzed hydroboration of termina

233 Bis(imino)pyridine complex [Ni{2,6-(ArN=CMe)(2)C(5)H(3)N}Cl]

234 The change in field strength of the bis(imino)pyridine coupled with the placement of the alkyl l

235 (S(Fe) = 0) with a closed-shell singlet bis(imino)pyridine dianion (S(PDI) = 0), demonstrating that

236 family of cationic, neutral, and anionic bis(imino)pyridine iron alkyl complexes has been prepared, a

237 Aryl-substituted bis(imino)pyridine iron and cobalt dihalide compounds, when

238 Reduced bis(imino)pyridine iron and cobalt dinitrogen compounds have

239 Bis(imino)pyridine iron bis(alkoxide) complexes have been sy

240 Catalytically competent bis(imino)pyridine iron diene and metallacycles relevant to

241 The bis(imino)pyridine iron dinitrogen complex (((i)Pr)PDI)Fe(N(

242 CHR (R = Ph, p-Tolyl, (t)Bu, Cy), to the bis(imino)pyridine iron dinitrogen complex, ((iPr)PDI)Fe(N(2

243 Addition of biphenylene to the bis(imino)pyridine iron dinitrogen complexes, ((iPr)PDI)Fe(N

244 The bis(imino)pyridine iron dinitrogen compound, ((iPr(TB))PDI)F

245 The bis(imino)pyridine iron dinitrogen compounds, ((iPr)PDI)Fe(N

246 Three new N-alkyl substituted bis(imino)pyridine iron imide complexes, ((iPr)PDI)FeNR ((iP

247 ffraction on all three alkyl-substituted bis(imino)pyridine iron imides established essentially plana

248 in isolation of catalytically competent bis(imino)pyridine iron metallacycle intermediates.

249 he molecular structures of the resulting bis(imino)pyridine iron metallacycles were established by X-

250 pared to the electronic structure of the bis(imino)pyridine iron N-aryl imide counterparts.

251 ation reactions, a detailed study of the bis(imino)pyridine iron-catalyzed hydromagnesiation of styre

252 Finally, displacement of the tridentate bis(imino)pyridine ligand over the course of the reaction re

253 A bis(imino)pyridine ligand scaffold was employed to synthesiz

254 Reaction of a phenyl-substituted bis(imino)pyridine ligand that is reduced by two electrons,

255 on effected directly at the redox-active bis(imino)pyridine ligand without an overall oxidation state

256 b), in which (Ph)I2P(2-) is a tridentate bis(imino)pyridine ligand, reacts with anilines to give the

257 Thus, the formal oxidative process is bis(imino)pyridine ligand-based (one electron is formally re

258 ion is observed to template a tridentate bis(imino)pyridine ligand.

259 oth the iron center and the redox-active bis(imino)pyridine ligand.

260 been prepared by the reaction of reduced bis(imino)pyridine ligands (I(2)P) with the trichloride salt

261 ly relevant, S = 1 iron complexes bearing 2-(imino)pyridine ligands, ((R)PI)FeL(2) ((R)PI = [2-(2,6-R

262 etal catalysts, coordinated by optimized bis(imino)pyridine ligands, show promise for industrial appl

263 ligand followed by N-H bond activation, bis(imino)pyridine modification, and H2 loss.

264 Treatment of the bis(imino)pyridine molybdenum eta(6)-benzene complex ((iPr)P

265 Me(3)), is chelate-based, resulting in a bis(imino)pyridine radical anion (S(PDI) = 1/2) antiferromag

266 mpounds antiferromagnetically coupled to bis(imino)pyridine radical anions.

267 Structure-activity relationships on bis(imino)pyridine substitution were also established with 2

268 quantites of 1,2-diarylhydrazines to the bis(imino)pyridine vanadium dinitrogen complex, [{((iPr)BPDI

269 ss 1,2-diarylhydrazine, formation of the bis(imino)pyridine vanadium imide amide compounds, ((iPr)BPD

270 (59)Co center, suggesting a principally bis(imino)pyridine-based SOMO.

271 lic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X](+) where M = Ru(II) or Os(II) and X ho

272 The resulting 2,6-bis(imino)pyridyl-Pd(II) motif contains a tridentate ligand,

273 al calculations suggest that the quinone and imino-quinone monoacetal coupling partners are exclusive

274 5'-neighbor base pair G(5) x C(20), the G(5) imino resonance remained sharp at 55 degrees C but broad

275 o water, these enhancements applied to every imino resonance throughout the RNA.

276 '-neighbor A(8) x T(17) base pair, the T(17) imino resonance was severely broadened at 55 degrees C.

277 reveals that the intensity of several of the imino resonances increases upon encapsulation.

278 The X(7) and Y(19) imino resonances were observed at 65 degrees C.

279 e show that sparse distance constraints from imino resonances, which can be readily obtained from rou

280 intramolecular cyclopropanation of an alpha-imino rhodium(II) carbenoid, leading to a transient 1-im

281 Its discovery revealed a class of amino/imino ribonucleoside artifacts that are generated during

282 Our data suggest that, relatively, imino-rich sequences maintain the canonical triple-helic

283 Imino spectral analysis of a (15)N-labeled central G cle

284 id-catalyzed rearrangement of the isolated 2-imino-spirochromenofurans 5 to 2-amino-spirochromenofura

285 erent positions of an orthogonally protected imino sugar as a common precursor.

286 straightforward protocol for the assembly of imino sugar containing nucleosides, establishing a new r

287 Analysis of an imino sugar inhibitor is consistent with tight binding o

288 ex and synthesis and evaluation of novel aza/imino sugar inhibitors.

289 This imino sugar was promising but had an EC(50) against DENV

290 y, GBA2 is reversibly inhibited by alkylated imino sugars that are in clinical use or are being devel

291 e related imidazolidin- and benzimidazolin-2-imino system.

292 was hypothesized to originate from its amino-imino tautomerism, which would explain its ability to ba

293 ral possible mechanisms, including the amino-imino tautomerization of the substrate base that may exp

294 Both the 2-imino-thiazolidine chemical method and the direct untarg

295 u prepared Zn(2+) complex of triazole linked imino-thiophenyl conjugate of calix[4]arene, [ZnL], was

296 nalog 3-benzothienyl-l-alanine (Bta) with an imino-to-sulfur substitution in the five-membered ring.

297 substituted benzimidazoles by intermolecular imino-transfer.

298 ATP analogs such as adenosine 5'-(beta,gamma-imino)triphosphate (AMP-PNP) and adenosine 5'-O-(thiotri

299 phate) (ATPgammaS), adenosine 5'-(beta,gamma-imino)triphosphate (AMP-PNP), and guanosine 5'-3-O-(thio

300 presence of ATP and adenosine 5'-(beta,gamma-imino)triphosphate but not by ADP.

301 iotriphosphate) and adenosine 5'-(beta,gamma-imino)triphosphate can stimulate helicase activity, as c