ライフサイエンスコーパス: immediate-early

1 The immediate early 1 (IE1) protein of HCMV also rescues p10

2 ot rescued to the same extent as that of the immediate early 1 (IE1) protein, suggesting that TAg exp

3 HLA class I-restricted CMV epitopes from the immediate early 1 gene of CMV, coinfection with genetica

4 n thresholds (50 spots per 250 000 cells for immediate early 1 or 100 spots per 250 000 cells for pho

5 The HCMV immediate early 1 protein cooperated with UL97-L1m to in

6 Two HHV-6 genes, U90 (immediate early 1 protein) and U100 (glycoproteins Q1 an

7 h STAT3 phosphorylation did not require MCMV immediate early 1, pM27, and late gene expression, it wa

8 sing Cas9 and guide RNAs targeting the BmNPV immediate early-1 (ie-1) and me53 genes effectively indu

9 ide pool of CMV phosphoprotein 65 (pp65) and immediate early-1 (IE-1) protein at the end of antiviral

10 Ag-expressing fibroblasts, expression of the immediate early 2 (IE2) protein was not rescued to the s

11 human cytomegalovirus (HCMV) transactivator immediate early 2 (IE2).

12 In this study, we show that the immediate-early 2 (IE2) protein may play a key role in H

13 The mouse cytomegalovirus (MCMV) immediate early 3 protein (611 amino acids; pIE611) is c

14 The major immediate early 62 (IE62) protein of varicella-zoster vi

15 The immediate early 62 protein (IE62) of varicella-zoster vi

16 The immediate early 62 protein (IE62) of varicella-zoster vi

17 for ribosome collisions and is required for immediate early activation of both SAPK (p38/JNK) and GC

18 Expression of viral immediate early (alpha) genes is followed sequentially b

19 poor recognition of target cells compared to immediate early and early antigen-specific CD8(+) cells.

20 ZIC2 localized at immediate early and early gene cluster regions of the KS

21 since deletion of ORF34 resulted in reduced immediate early and early lytic gene expression and bloc

22 rly, and late EBV RNAs were all upregulated, immediate early and early viral proteins but not late vi

23 a cytopathic effect and the accumulation of immediate early and late viral proteins.

24 We have previously shown that ORF45, an immediate-early and tegument protein of Kaposi's sarcoma

25 luorescent protein (tagBFP), marking latent, immediate early, and late viral gene expression, respect

26 effects of these visual cycle inhibitors on immediate, early, and late phases of cone photopic visio

27 ingly, earlier expression from constitutive, immediate-early, and early promoters did not significant

28 rus (CMV) primarily reflect anti-CMV pp65 or immediate early antigen 1 (IE-1) activity.

29 In contrast to US28, HCMV-encoded immediate early antigen was detected in less than 5% of

30 Here, we show that FOSL1 is the main immediate early AP-1 member induced by melanoma oncogene

31 Differential modulation of immediate early cellular transcripts (e.g., c-Jun and mu

32 from the viral LTR but not from an internal immediate-early CMV promoter, suggesting a role of SSRP1

33 ngation) to promoters of NF-kappaB-dependent immediate-early cytokine genes, in ATM knockdown cells.

34 Immediate early E1A protein levels are unaffected by the

35 While immediate early, early, and late EBV RNAs were all upreg

36 Immediate early, early, and late gene expression were qu

37 s well as inhibiting the expression of viral immediate-early, early and late genes when added at vari

38 assified into three distinct kinetic groups: immediate-early, early, and late classes.

39 Here, we report that an immediate-early event of Arg-auxotrophic response involv

40 , functional magnetic resonance imaging, and immediate early gene (c-fos) expression to assess the hy

41 Immediate early gene (IEG) activity mapping has been wid

42 Serum response factor (SRF) mediates immediate early gene (IEG) and cytoskeletal gene express

43 In the cortex, the immediate early gene (IEG) ARC was increased in VNS rats

44 repair, as a key player in the regulation of immediate early gene (IEG) expression underlying the con

45 vity in the IL-PFC as evidenced by increased immediate early gene (IEG) expression.

46 Furthermore, we found that expression of the immediate early gene (IEG) Homer1a (H1a) and its subsequ

47 Immediate early gene analysis identified T-types exhibit

48 l protein 0 (ICP0) of HSV-1 is encoded by an immediate early gene and plays a fundamental role during

49 tes an initial and transient increase of the immediate early gene apc/ebp mRNA, a prolonged increase

50 The immediate early gene Arc (also Arg3.1) produces rapid ch

51 n compared with vehicle-pretreated rats, the immediate early gene c-Fos (a marker of neuronal activat

52 ons to light, and enhances expression of the immediate early gene c-fos in the SCN, which is involved

53 sion in the LS, stress-induced expression of immediate early gene c-fos, and anxiety-related and depr

54 erential patterns of immunoreactivity of the immediate early gene c-Fos, with a blunted response to t

55 a quantitative analysis of expression of the immediate early gene cFos and generalized linear mixed-e

56 n-specific markers, retrograde tracings, and immediate early gene colocalizations.

57 of artificial aptazymes into the adenoviral immediate early gene E1A enables small-molecule-triggere

58 in (ERK/MAP) kinase signaling but not on the immediate early gene EGR-1.

59 was identified as a downstream target of the immediate early gene Egr1.

60 We showed that the immediate early gene Egr3 has long-term effects on drug-

61 pression of Bpifa2 in mice lacking Nur77, an immediate early gene expressed in the kidneys during AKI

62 CaMPARI2 photoconversion was correlated with immediate early gene expression and higher FRs ex vivo a

63 s of training-induced transient waves of Arc immediate early gene expression critical for synaptic pl

64 Molecular analyses of neural activity via immediate early gene expression indicate a functional ro

65 e cell RNAseq analysis of neurons divided by Immediate Early Gene expression levels.

66 Immediate early gene expression patterns were informativ

67 Analysis of immediate early gene expression revealed parallel up-reg

68 ity at cellular resolution through profiling immediate early gene expression using immunostaining and

69 A2 with no effect on neuronal firing rate or immediate early gene expression.

70 B phosphorylation that coordinately regulate immediate early gene expression.

71 g-related transcripts including the expected immediate early gene Fos and Stk11, a master kinase of t

72 stochemical detection of the tracers and the immediate early gene Fos.

73 We found that activity-dependent immediate early gene H1a is critical for establishing no

74 report a novel role of an activity-dependent immediate early gene Homer1a (H1a) in these processes.

75 These changes are driven by the immediate early gene Homer1a and signaling from group I

76 he mechanistic level, we show that the HSV-1 immediate early gene ICP22 binds the CD80 promoter and t

77 how that activation of a learning-associated immediate early gene in rat olfactory cortices is uninte

78 e have examined whether deletion of Narp, an immediate early gene induced by electroconvulsive seizur

79 A whole brain immediate early gene mapping highlighted the dorsolatera

80 Stabilization of a transiently expressed immediate early gene mRNA by a repeated training trial m

81 y presynaptic expression of the synaptogenic immediate early gene NPTX2 by pyramidal neurons.

82 ct binding of HSV-1 ICP22, the product of an immediate early gene of HSV-1, to the promoter of CD80.

83 e, upstream of the predicted promoter of the immediate early gene open reading frame 63 (ORF63).

84 At excitatory glutamatergic synapses, the immediate early gene product Arc/Arg3.1 couples synaptic

85 The pattern of expression of the immediate early gene product cFos was used to identify k

86 in condition, Homer1a, an activity-dependent immediate early gene product, disrupted the persistent m

87 To identify activated neurons, the immediate early gene product, Fos protein, was labeled.

88 lified ERK1/2 activation, growth factor-like immediate early gene regulation and EGR1 protein express

89 Therefore, understanding of immediate early gene regulation might add insights into

90 Using immediate early gene reporter mice, active cells express

91 Arc is an immediate early gene that is unique among neuronal mRNAs

92 cytoskeleton-associated protein (Arc) is an immediate early gene that modulates neuronal plasticity

93 GNIFICANCE STATEMENT How does the pattern of immediate early gene transcription in the brain relate t

94 s function in herpes simplex virus 1 (HSV-1) immediate early gene transcription, our findings suggest

95 Nur77 is an immediate early gene whose expression is rapidly upregul

96 imulates the expression of c-Fos, a neuronal immediate early gene with key roles in synaptic plastici

97 activation (as the expression pattern of the immediate early gene ZENK) during sleep in juvenile zebr

98 Thus, altered expression of the immediate early gene Zif268 may contribute to lower leve

99 nce imaging and in situ hybridization of the immediate early gene zif268, respectively.

100 We review the "Immediate Early Gene" (IEG) response, the starting point

101 Arc/Arg3.1, an activity regulated immediate early gene, is essential for learning and memo

102 activity-induced transcription of a neuronal immediate early gene; and 3) in vivo in Drosophila melan

103 ulated cytoskeletal-associated protein (Arc) immediate-early gene (IEG) expression and changes in BLA

104 solidation is associated with CB1R-dependent immediate-early gene (IEG) expression and changes in exc

105 The induction of immediate-early gene (IEG) expression in brain nuclei in

106 s work has shown that epigenetic changes and immediate-early gene (IEG) induction in stress-activated

107 Arc is a cellular immediate-early gene (IEG) that functions at excitatory

108 e cells (IGCs), many of which upregulate the immediate-early gene Arc after male-male social experien

109 We show that the plasticity-associated immediate-early gene Arc is selectively expressed in IGC

110 as confirmed by immunohistochemistry for the immediate-early gene c-Fos and behavioral tracking, whic

111 experiments indicated that expression of the immediate-early gene c-fos was aberrantly elevated in th

112 We report activation of the immediate-early gene Egr-1 in the lateral amygdala (LA),

113 ell measured using brain mapping analyses of immediate-early gene expression and produced a robust si

114 inhibitor, OSMI-1, affects initiation of HSV immediate-early gene expression and viral replication.

115 severely impaired behavioral stimulation of immediate-early gene expression in the mPFC, suggesting

116 p90RSK phosphorylation and the induction of immediate-early gene expression.

117 and Period2 (Per1 and Per2), as well as the immediate-early gene Fos in the SCN, dorsal hippocampus,

118 ients tested had expression of the EBV major immediate-early gene in the blood indicative of active E

119 95-mediated memory maintenance using ex vivo immediate-early gene mapping, in vivo neuronal recording

120 n the expression of c-Fos and C/EBPbeta, two immediate-early gene markers of neuronal activity.

121 efects in the expression or activity of this immediate-early gene may also contribute to the pathophy

122 Our findings implicate an immediate-early gene product, Egr1, as part of the mecha

123 ion, SMin92 accumulated representative viral immediate-early gene products, early gene products, and

124 the levels of Arc (also known as Arg3.1), an immediate-early gene that is required for long-term memo

125 CCN1 is a product of an immediate-early gene that is transcriptionally induced i

126 n of methionine import, leading to decreased immediate-early gene translation without significant tox

127 ed GABABR activity reduced the expression of immediate-early gene-encoded protein Arc/Arg3.1, effecto

128 significant increases in mRNA expression of immediate early genes (Arc, Egr1), Bdnf and its receptor

129 Coexpression of immediate early genes (for example, Egr1, Fos, Dusp1) an

130 of roscovitine treatment, transfection with immediate early genes (IE), and infection with a recombi

131 ering transcription factors and promoters of immediate early genes (IEG) accessible to PARP1-bound ph

132 Among these immediate early genes (IEG), members of the Early growth

133 thin this set of genes we identified several Immediate Early Genes (IEG), which were highly expressed

134 al activation induces rapid transcription of immediate early genes (IEGs) and longer-term chromatin r

135 g-related elevation in the expression of the immediate early genes (IEGs) Arc/Arg3.1 and Egr-1 in the

136 itiation and the release of paused RNAPII at immediate early genes (IEGs) following transcriptional a

137 tion factor (NELF) complex upon induction of immediate early genes (IEGs) in neurons.

138 Transcription of immediate early genes (IEGs) in response to extrinsic an

139 Alternatively, post hoc staining of immediate early genes (IEGs) indicates highly active cel

140 s been shown for Egr-2, all of which are the immediate early genes (IEGs) of the Erk1/2 pathway.

141 ence-driven induction of activity, including immediate early genes (IEGs) such as Fos, Arc and Egr1.

142 In addition and unlike mammalian immediate early genes (IEGs), fly ARGs do not have short

143 fic expression patterns of JUN, FOS and EGR1 immediate early genes (IEGs), reflected by the presence

144 ch to dissect how Erk activity is decoded by immediate early genes (IEGs).

145 lize epidermal growth factor (EGF)-inducible immediate early genes (IEGs).

146 tion elongation of the serum response genes (immediate early genes [IEGs]) FOS, EGR1, and cJUN.

147 We found dosage-dependent activation of immediate early genes after 1 h.

148 nes that responded to fight outcome included immediate early genes and genes involved in neuroplastic

149 timulation, activated ERK1/2 is recruited to immediate early genes and phosphorylates INTS11, the cat

150 Insulin-stimulated expression of immediate early genes and proliferation were also potent

151 mulus-dependent recruitment of Integrator at immediate early genes and their enhancers.

152 revealed widespread changes in expression of immediate early genes and their targets, supporting the

153 tamine prevents Cav1.2-mediated induction of immediate early genes and transcription factors, and ina

154 At the molecular level, immediate early genes are among the synaptic plasticity

155 on factor ELK-1 stimulates the expression of immediate early genes at the onset of the cell cycle and

156 ychostimulant addiction, blocks induction of immediate early genes by DRD1 stimulation, and prevents

157 hat Ikaros did not bind to either of the EBV immediate early genes BZLF1 and BRLF1.

158 ssed long-term changes in activity-dependent immediate early genes c-Fos and Arc/Arg3.1 in auditory a

159 nsistent modulation of the expression of the immediate early genes c-fos and egr-1 upon change in num

160 at fear conditioning drove expression of the immediate early genes cFos and Nr4a2 in the hippocampus,

161 One of these immediate early genes encodes naked cuticle homolog 1 (N

162 associated with increased expression of the immediate early genes Fos and FosB and the NMDA receptor

163 s and downstream early and late genes, while immediate early genes from other loci remain unaffected.

164 was associated with decreased expression of immediate early genes in rat GC of both sexes, and with

165 Deletion of YAP/TAZ blocks the induction of immediate early genes in response to mitogenic stimuli.

166 g one population expressing higher levels of immediate early genes indicative of a homeostatic activa

167 n inducing Kruppel-like factor 2 and several immediate early genes of the AP1 and Egr family.

168 trongly turning on expression of both of the immediate early genes of the virus, probably by directly

169 onal activity causes the rapid expression of immediate early genes that are crucial for experience-dr

170 aintaining seizure activity and induction of immediate early genes that control hippocampal excitabil

171 (DUSP1); both known to be activity-dependent immediate early genes that respond to stimuli in the bra

172 The FGFR immediate early genes that were identified include those

173 hnique based on the cellular distribution of immediate early genes to examine the effect of LC activa

174 ventral hippocampus, whereas upregulation of immediate early genes was observed in both dorsal and ve

175 After CO2 asphyxiation, several immediate early genes were expressed at lower levels in

176 itially induce partially overlapping sets of immediate early genes without sustaining the response.

177 of proper viral entry, normal expression of immediate early genes, and viral DNA replication.

178 Moreover, upregulation of immediate early genes, complement factors, apoptosis, an

179 Immediate early genes, represented by AP-1 complex, are

180 Cs induced a robust expression of a panel of immediate early genes, which included the Nr4a subfamily

181 horylation and, in most cases, expression of immediate early genes.

182 at limit transcription of plasticity-related immediate early genes.

183 tency to reactivation requires expression of immediate early genes.

184 g variables examined and differed from other immediate early genes.

185 -related genes and a decreased expression of immediate early genes.

186 se that is similar to that of protein-coding immediate early genes.

187 that closely resemble the dynamics of known immediate-early genes (IEGs) and this enables a comprehe

188 Immediate-early genes (IEGs) are rapidly activated after

189 Here, we used the expression of immediate-early genes (IEGs), protooncogene, c-Fos, and

190 or that is functionally deleted for all five immediate-early genes and the 15-kb internal repeat regi

191 that is required for transactivation of the immediate-early genes of herpes simplex virus (HSV).

192 overexpression of the FosB, ARC, and Zif268 immediate-early genes only in rats experiencing abnormal

193 ng RNA (siRNA) reduced the expression of HSV immediate-early genes, in addition to reducing viral yie

194 CMV infection by targeting the expression of immediate-early genes.

195 We demonstrate that the viral immediate early ICP0 protein plays a dominant role in th

196 The levels of immediate early (IE) (IE2), early (E) (pp65), and early/

197 HCF-1 stabilizes the viral Immediate Early (IE) gene enhancer complex and mediates

198 Although viral immediate early (IE) gene expression is essential for HC

199 Immediate early (IE) gene expression significantly incre

200 HSV mutants defective in multiple immediate early (IE) gene functions are highly defective

201 38-L and pUL138-S are able to suppress major immediate early (IE) gene transcription and the generati

202 ase (RSK) activation, which is induced by an immediate early (IE) gene-encoded tegument protein calle

203 HSV mutants defective in multiple immediate early (IE) genes establish a quiescent infecti

204 sociated with herpes simplex virus 1 (HSV-1) immediate early (IE) promoters and is necessary for IE g

205 For example, herpes simplex virus 1 (HSV-1) immediate early (IE) protein ICP0 overcomes the restrict

206 MP1 expression is activated by the BRLF1 (R) immediate early (IE) protein.

207 Indeed, the major immediate early (IE) proteins IE1 and IE2 stimulated the

208 sustained activation of ERK-RSK induce viral immediate early (IE) transcription and late transcriptio

209 al coactivator of herpes simplex virus (HSV) immediate early (IE) transcription, suggesting that OriP

210 tes VZV replication by transactivating viral immediate early (IE), early (E), and late (L) genes.

211 tone H3 at serine 10 or 28 and expression of immediate-early (IE) genes.

212 sequently reduced, but not eliminated, by an immediate-early (IE) or early (E) virus-encoded function

213 sed on the regulatory functions of ICP27, an immediate-early (IE) protein of herpes simplex virus 1 (

214 Human cytomegalovirus (HCMV) immediate-early (IE) proteins that are endogenously expr

215 hly regulated, with sequential expression of immediate-early (IE), early (E), and late (L) gene trans

216 ranscription of mouse cytomegalovirus (MCMV) immediate early ie1 and ie3 is controlled by the major i

217 In comparison, immediate early IRF3 activation was not observed in infl

218 rnative promoters within the canonical major immediate early locus.

219 eolar macrophages from HCMV carriers express immediate early lytic genes and produce infectious virus

220 , without much effect on lytic switch ORF50, immediate early lytic K8, and viral interferon-regulator

221 epitope if KCSRNRQYL is expressed within the immediate-early MCMV gene ie2 The same epitope expressed

222 the proximal AP-1 binding site in the major immediate early (MIE) enhancer results in inefficient re

223 The human cytomegalovirus (HCMV) major immediate early (MIE) gene is essential for viral replic

224 infected HPCs is reexpression of viral major immediate early (MIE) genes.

225 vely link human cytomegalovirus (HCMV) major immediate early (MIE) latent-lytic switch activation wit

226 Two of the alternative major immediate early (MIE) transcripts initiate in the first

227 expression impacts the accumulation of major immediate early (MIE) transcripts.

228 intron A of the cytomegalovirus (CMV) major immediate-early (MIE) gene and functions to repress MIE

229 tly reduced the accumulation of late but not immediate early or early viral antigens and had no appre

230 ine type) was found in the resected stomach; immediate early (ORF63p) and late (gE) VZV proteins were

231 matintranscription (FACT) binds to the major immediate early promoter (MIEP) and that inhibition of t

232 ion of the core promoter region of the major immediate early promoter (MIEP) from a plasmid containin

233 The major immediate early promoter (MIEP) of human cytomegalovirus

234 t 19S RP subunits are recruited to the major immediate early promoter (MIEP) that directs IE transcri

235 ction represses transcription from the major immediate early promoter (MIEP) within 24 h.

236 We recently determined that the major immediate early promoter (MIEP), which is primarily resp

237 tte under the control of the cytomegalovirus immediate early promoter into the VC2 vector in place of

238 GPCR results in transcription from the major immediate early promoter, the production of extracellula

239 early ie1 and ie3 is controlled by the major immediate early promoter/enhancer (MIEP) and requires di

240 y blocking the activation of the viral major immediate-early promoter by XBP1s and ATF6.

241 ty of promoters, such as the cytomegalovirus immediate-early promoter, the IFN-beta promoter, and a p

242 ls by synergistically activating the two EBV immediate early promoters (Zp and Rp).

243 KAP1 also binds to EBV OriLyt and immediate early promoters in a CTAR3-dependent manner, a

244 CMV phosphoprotein 65 (pp65)- and immediate early protein 1-specific multifunctional T-cel

245 R-200 miRNA family members target the UL122 (immediate early protein 2) 3' untranslated region, resul

246 The immediate early protein ICP0 of herpes simplex virus 1 (

247 The herpes simplex virus 1 (HSV-1) immediate early protein ICP0 performs many functions dur

248 DNA-PKcs and in cells cotransfected with the immediate early protein ICP0, which degrades DNA-PKcs.

249 larities with herpes simplex virus 1 (HSV-1) immediate early protein ICP0, which stimulates lytic HSV

250 The herpes simplex virus 1 (HSV-1) immediate early protein ICP22 plays several roles in the

251 t this recruitment is dependent on the viral immediate early protein ICP22.

252 In addition, synthesis of the immediate early protein ICP27 causes partial inhibition

253 Here, we demonstrate that the HSV-1 immediate early protein ICP27 induces DoTT by directly b

254 Human cytomegalovirus (HCMV) immediate early protein IE1 and the tegument protein pp7

255 n.IMPORTANCE HSV-1 ICP0 is a multifunctional immediate early protein key to effective replication in

256 The immediate early protein of the virus ICP0 plays major ro

257 patients, stratified by their baseline CMV (immediate-early protein 1)-specific CMI risk, were rando

258 T inhibitors prevent expression of the viral immediate-early protein BZLF1.

259 the interaction between the C-USP7 and HSV-1 immediate-early protein ICP0 (infected cell protein 0),

260 Herpes simplex virus type 1 immediate-early protein ICP0 is an E3 ubiquitin ligase o

261 Human cytomegalovirus immediate-early protein pUL37 x 1 induces Bax mitochondr

262 The human cytomegalovirus immediate-early protein pUL37x1 induces the release of C

263 reased and prolonged expression of the viral immediate early proteins.

264 erentially affect the ability of the two EBV immediate-early proteins, BZLF1 (Z) and BRLF1 (R), to in

265 s normally overcome by viral tegument and/or immediate-early proteins.

266 IK-1 also complexed with the EBV immediate early R protein in coimmunoprecipitation assay

267 formation, associates with the expression of immediate early response 3 (Ier3) as part of a prooncoge

268 Here, we report an unexpected role for immediate early response gene X-1 (IEX-1), a downstream

269 We also show that a number of immediate early response genes (IEGs) are responsible fo

270 flammation by upregulating the expression of immediate early response genes, followed by activation o

271 of non-coding RNAs in the attenuation of the immediate early response in a small RNA sequencing datas

272 hways, the key molecular determinants during immediate early response remain elusive.

273 Since GR activation is an immediate early response to stress, we tested whether th

274 Genes within the former type often belong to immediate early response transcription factors, while ge

275 ormal conditions, it initiates the so-called immediate early response, which encompasses the transien

276 and the multifunctional stress response gene immediate early response-3 (IER3) has a crucial role und

277 n data we have examined the induction of the immediate-early response in unparalleled detail, across

278 The immediate-early response mediates cell fate in response

279 tial therapeutic intervention point at a pre-immediate early stage for the inhibition of HCMV infecti

280 amma inhibited VZV gene expression after the immediate early stage of infection and abrogated IE62-me

281 svirus (KSHV) is a gammaherpesvirus-specific immediate-early tegument protein.

282 MIE mRNA was the most abundant transcript at immediate early times, the novel MIE transcripts accumul

283 The Epstein-Barr virus (EBV) immediate early transactivator Zta plays a key role in r

284 on, indicating important roles for the BZLF1 immediate early transactivator, the BHRF1 vBcl-2 homolog

285 irus engineered with a mutation in the major immediate-early transactivator protein RTA.

286 ings reveal a feed-forward interplay between immediate early transcription of AP-1 and Hippo pathway

287 The immediate early transcription unit 1 (IEtu1) promoter dr

288 that cooperatively transactivates the BoHV-1 immediate early transcription unit 1 (IEtu1) promoter th

289 ed GR-mediated transactivation of the BoHV-1 immediate early transcription unit 1 (IEtu1) promoter, t

290 The immediate early transcription unit 1 (IEtu1) promoter, w

291 asone-mediated transactivation of the BoHV-1 immediate early transcription unit 1 and HSV-1 ICP0 prom

292 The immediate early transcription unit 1 promoter (IEtu1) dr

293 Further, EDF1 regulates an immediate-early transcriptional response to ribosomal co

294 ever, the extent of their involvement in the immediate-early transcriptional response, and their wide

295 We demonstrate that immediate early transcripts arising from reactivation or

296 The accumulation of immediate early transcripts differed between MRC5 cells

297 idization (RNA-FISH) of the intron region of immediate early transcripts, we visualized active transc

298 usceptibility to the inhibition of early and immediate early viral gene expression.

299 ells successfully based on the expression of immediate early viral protein.

300 of cells with CRISPR targeting ICP0 plus the immediate early viral proteins, ICP4 or ICP27, completel