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1 idth of the ORV zone and proportion of hosts immunized.
2 ups of 15 healthy, malaria-naive adults were immunized.
5 f 66 healthy term infants from a 2011 study, immunized according to the same schedule with the same v
7 tibody from an Indian dromedary camel (ICab) immunized against a bacterial 14TM helix transporter, No
8 challenging a S. thermophilus strain CRISPR-immunized against a set of virulent phages, we found one
9 , patients with Alzheimer's disease actively immunized against amyloid-beta can remain virtually plaq
10 es of IgG-secreting cells we measure in mice immunized against Tetanus Toxoid under largely varying c
11 f AAVs and Cas9 in mice that were previously immunized against the AAV vector and the Cas9 cargo.
12 HCMV infection, we show that rhesus macaques immunized against viral interleukin-10 (IL-10) manifest
16 Subsequently, the humanized antibody was de-immunized and site-specific mutations were introduced to
18 total of 1375 participants were randomized, immunized, and followed for safety and immunogenicity.
19 , in nature, bacteria are frequently not pre-immunized, and phage populations are often not clonal, e
20 ve transfer of sera from VSV-eGFP-SARS-CoV-2-immunized animals also protects naive mice from SARS-CoV
21 pes targeted in polyclonal sera, elicited in immunized animals as well as in an HIV-1-infected elite
22 with L. major-infected sand flies, while non-immunized animals develop large and progressive lesions
23 challenge, unimmunized control and s.c.-s.c.-immunized animals developed Chlamydia-specific intestina
25 h.SOSIP immunogen induced in the majority of immunized animals higher neutralization titers against b
29 lus-immunized animals, whereas slow delivery-immunized animals targeted a more diverse set of epitope
33 une response detected after vaccination, all immunized animals were protected from disease and death
35 on of binding antibodies and, in a subset of immunized animals, in the induction of detectable NAb, s
36 -neutralizing epitopes by conventional bolus-immunized animals, whereas slow delivery-immunized anima
38 antigenic variants in naturally infected or immunized animals.IMPORTANCE Avian influenza H7N9 viruse
39 nd were studied by indirect methods, such as immunizing animals with myelin components or feeding the
41 ock-in BCR does not functionally engage with immunizing antigen, we found that chronic immunization i
46 identify novel biomarkers of senescence, we immunized BALB/c mice with senescent mouse lung fibrobla
48 e BLT model for HIV-1 vaccine development by immunizing BLT mice against the conserved viral Gag prot
57 CD4(+)CD62L(-)CD44(hi) T cells from gliadin-immunized C57BL/6 mice and were fed with an AIN-76A-base
60 ilt from mononuclear cells isolated from the immunized camel and purified the antibody from Escherich
62 Fel d 1-induced allergy in human subjects by immunizing cats against their own major allergen, Fel d
64 CV7-immunized children, carriage among PCV13-immunized children was significantly lower for serotypes
66 valent pneumococcal conjugate vaccine (PCV7) immunized children, N = 567, enrolled between November 2
68 ses often forces policymakers to rely on non-immunizing control measures, such as vector control, to
69 on-level loss of immunity resulting from non-immunizing controls and is seen in a variety of models w
70 and is seen in a variety of models when non-immunizing controls are used against an infection that c
71 t stopping control programs that rely on non-immunizing controls, our results strongly argue that the
72 ing experimental and reference antisera from immunized, convalescent, and naive animals (n = 172).
74 Importantly, the offspring of UC-3 F VLP-immunized dams showed significant protection from lung p
77 producing CD4(+) but not CD8(+) T cells from immunized donor mice were sufficient for eliminating Chl
79 dataset on the basis of documented previous immunizing events (transplant, pregnancy, or transfusion
85 -neutralizing human monoclonal antibodies by immunizing genetically engineered mice that have a full
87 Here, we further showed that sera from V160-immunized HCMV-seronegative subjects have attributes sim
89 s differed between control and inhibin alpha-immunized heifers, casting further doubt on thecal inhib
96 ry CD8 T cells from the livers of previously immunized IFN-1 signaling-deficient mice confers greater
98 eflect a systemic immune deficiency, because immunized IL-1R1(-/-) mice survived subsequent lethal VA
100 alpis, the sand fly vector of leishmaniasis, immunize individuals with L. longipalpis salivary antige
103 lenged with Leishmania major parasites, mice immunized intradermally exhibited significant protection
108 (-/-) mice were sensitized epicutaneously or immunized intraperitoneally with ovalbumin (OVA) and cha
109 t phage-antibodies against gluten from a non-immunized library of human single-domain antibodies (dAb
110 ncoded HVACC inhibitor by first isolating an immunized llama nanobody (nb.F3) that binds auxiliary HV
115 we further combined DJ NS1 with DENV NS3 to immunize mice and showed activation of Ag-specific CD4(+
116 When we used L. lactis-derived PfCSP4/38 to immunize mice, it elicited high levels of functional ant
119 earlier and stronger protective responses in immunized mice after reinfection with T. cruzi than thos
120 /68 viruses and protection for a majority of immunized mice against a heterologous A/California/07/20
121 totic colon carcinoma CT26 cells efficiently immunized mice against challenge with a breast cancer ce
122 titer of neutralizing antibodies in sera of immunized mice against pseudotyped lentivirus reporter o
124 ciated with T cells sharing common TCRs from immunized mice and from patients with food allergy.
125 c CD4(+) T cell proliferation in LdCen(-/-) -immunized mice and impaired protection against virulent
128 h S Typhimurium, were present in the sera of immunized mice but did not bind live intact Salmonella b
130 nt for interferon responses in MVA-B13R/SHIV-immunized mice compared to the responses in MVA/SHIV-imm
131 nes were significantly higher in LdCen(-/-) -immunized mice compared with nonimmunized mice that resu
132 ority of HCMVpp65(422-439) and TAF9(134-144) immunized mice developed proteinuria, and their renal pa
133 lls after an established humoral response in immunized mice does not impair protection from a homolog
134 lts show that DCs isolated from protectively immunized mice exhibit enhanced transcriptional activati
135 Neutrophils from ear dLN of LdCen(-/-) -immunized mice exhibited heightened expression of costim
136 However, rAd5-S1- but not rAd5-S1/F/CD40L-immunized mice exhibited marked pulmonary perivascular h
137 e parasitized Nalpha subset from LdCen(-/-) -immunized mice exhibited much stronger Ag-specific CD4(+
138 cific IgG and IgA that were protective, with immunized mice exhibiting more rapid bacterial clearance
139 teraction of LdCen(-/-) with neutrophils, we immunized mice intradermally in the ear pinna with LdCen
142 d PCs after a boost with rLBNSE, rLBNSE-IL-7-immunized mice promptly produced a more potent secondary
144 uted from the glomeruli of HCMVpp65(422-439) immunized mice showed cross-reactivity with TAF9(134-144
147 epertoire diversity: Shannon indices of 4 in immunized mice to 2.6 in persistently infected mice.
149 pearance of the IgG-SCs within the spleen of immunized mice was fast (<24 h) and this early response
150 s played a role in Tfh support of the GC, we immunized mice with a T cell-restricted deletion of the
154 tion would enhance this vaccine response, we immunized mice with inactivated vaccine and injected Ag-
156 to the challenged animals compared with sham immunized mice, although none of our candidates were as
157 A in bronchoalveolar lavage (BAL) fluid from immunized mice, and Yersinia-specific CD4(+) and CD8(+)
158 well as IL-17, in both lungs and spleens of immunized mice, conferring comprehensive Th1- and Th2-me
159 compromise vaccine efficacy, sera from spike-immunized mice, nonhuman primates, and humans were evalu
170 rus (RRV) has shown potential as a vector to immunize monkeys with antigens from simian immunodeficie
172 ertussis (aP)- than wP-vaccinated infants of immunized mothers, yet quality of antibodies, measured a
174 )17 immunity, we transplanted irradiated MPO-immunized MPO-deficient mice with bone marrow from eithe
175 nt mice; we also transplanted irradiated MPO-immunized MPO/IL-17A double-deficient mice with bone mar
176 d Daf1(-/-) B2 cells and in hen egg lysozyme-immunized muMT recipients of MD4 B2 cells on each geneti
185 ersonalized neoantigen-targeting vaccines to immunize patients newly diagnosed with glioblastoma foll
187 number of cases of meningococcal disease in immunized patients being treated with eculizumab and sug
191 ion of tobacco and alcohol, obesity control, immunizing populations against hepatitis B virus infecti
192 addressing the weakest links, which includes immunizing populations in insecure areas and/or with dis
194 Further protective efficacy was observed in immunized rabbits following intramedullary challenge wit
195 o the common glycan hole can be achieved, we immunized rabbits with B41 SOSIP (gp120-gp41 disulfide [
199 mpted to mask immunodominant glycan holes by immunizing rabbits with ICs consisting of the BG505 SOSI
200 , whereas uptake in the remote myocardium of immunized rats and controls was low (SUV(mean), 0.4 +/-
208 re is no formal recommendation about testing immunized subjects (in particular, healthcare workers [H
212 e: current heuristic methods are designed to immunize vital nodes or modify a network to a specific o
213 Healthy, adult malaria-naive volunteers were immunized with 3 intramuscular injections of 20 mug (n =
214 hteen IBH-affected horses were recruited and immunized with 300 mug of eIL-31-CuMVTT vaccine or place
219 virus (RSV) infection of children previously immunized with a nonlive, formalin-inactivated (FI)-RSV
220 and somatic hypermutation in cells from mice immunized with a vaccine target, a multifunctional enzym
221 ty-two rhesus macaques (Macaca mulatta) were immunized with Ad26 vectors that encoded S variants or s
222 CD1c+CD11c+ human DCs isolated from HIS mice immunized with adenoviruses expressing malaria/human imm
229 m challenge with leukemia if they were first immunized with CnB-deficient leukemia, suggesting robust
232 antigen-specific antibody responses in mice immunized with dengue virus envelope domain III protein
236 an controls (n = 78) to be age-appropriately immunized with DTaP (41% vs 89%, P < .001) and PCV (59%
239 nfection of seronegative children previously immunized with formalin-inactivated (FI) RSV has been as
241 VZV-seropositive Kenyan women (n = 44) were immunized with high-dose live attenuated VZV vaccine, an
242 er, for one reconstitution cohort, some mice immunized with iDCpp65 showed GVH-like signs on the skin
246 We previously showed that humanized mice immunized with long-lived induced-dendritic cells loaded
247 Fc-mediated protective mechanisms in animals immunized with monovalent versus polyvalent vaccines.
251 an complement-mediated SBA responses in mice immunized with NOMV with overexpressed FHbp subfamily B
254 - and post-immunization sera from 133 adults immunized with one of three types of influenza vaccines
256 VA (nOVAmax) were performed before mice were immunized with or without gastric acid-suppression medic
257 nx significantly dropped in animals formerly immunized with PE-PilA, and in chinchillas, signs of oti
258 ated invariant T cells in healthy volunteers immunized with PfSPZ Vaccine and challenged by CHMI usin
262 single-domain antibodies (VHHs) from a llama immunized with prefusion-stabilized coronavirus spikes.
265 serum nAb titers from a total of 78 animals immunized with recombinant native-like (SOSIP) Env trime
267 we show that IFN-1 signaling-deficient mice immunized with replication-competent sporozoites exhibit
276 s were comparable between adults and infants immunized with the alum/MNrgp120 vaccine (gp120 median f
279 and 804 [adults], P = 0.50), whereas infants immunized with the MF59/SF-2 rgp120 vaccine had higher-m
280 ing prechallenge and after challenge of pigs immunized with the naturally attenuated isolate OURT88/3
283 smoke exposure cessation, and the mice were immunized with the P6 lipoprotein from nontypeable Haemo
284 ) and developed better protection than those immunized with the parent virus LBNSE or the GM-CSF-expr
291 vaccine compounds, with antibodies from mice immunized with this physical mixture control shown to ef
295 ungs of the RSV-challenged offspring of dams immunized with UC-3 F VLPs than in the lungs of the RSV-
296 ers in the sera of the offspring of the dams immunized with UC-3 F VLPs were significantly higher tha
298 V-2, mice that expressed human ACE2 and were immunized with VSV-eGFP-SARS-CoV-2 show profoundly reduc
300 vide synopses of their candidate vaccines to immunize women to protect against congenital CMV disease