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1 e engrafted into neonatal mice that are both immunodeficient and deficient for myelin basic protein.
2 ve transfer of diabetes by CD4(+) T cells to immunodeficient and diabetes-resistant NOD.scid mice was
3 lts in a significant increase in survival in immunodeficient and immunocompetent models of pHGG and D
5 r stromal interaction molecule 1 (STIM1) are immunodeficient and prone to chronic infection by variou
6 ice, AtmR3016H (Atm(R/R) ) mice were viable, immunodeficient, and displayed spontaneous craniofacial
8 -TAM pool, using orthotopically xenografted, immunodeficient, and syngeneic mouse models with genetic
9 tence of TIL after adoptive transfer into an immunodeficient animal model and augments antitumor immu
10 rounds as a model, we show that ticks fed on immunodeficient animals demonstrate decreased fibrinogen
11 dation product) were evident in ticks fed on immunodeficient animals in comparison to ticks fed on im
12 orgement weights were noted for ticks fed on immunodeficient animals in comparison to ticks fed on im
13 syringae strains into virulent pathogens in immunodeficient Arabidopsis thaliana under high humidity
14 activity in immunocompetent C57BL/6 but not immunodeficient athymic mice, leading to specific immune
16 in the abdominal aorta of a severe combined immunodeficient Beige mouse model supports normal blood
18 Humanized nonobese diabetic severe combined immunodeficient common gamma chain-deficient stem cell f
19 ncer cells are orthotopically implanted into immunodeficient consomic strains and tumor metrics are q
20 in the percentage of dying (TUNEL+) cells in immunodeficient dystrophic mouse muscles at the times af
23 was attenuated in C57BL/6 wild-type mice and immunodeficient gp91(-/-) phox mice and was effective as
24 n Toll-like receptor signaling, are severely immunodeficient, highlighting the paramount role of IRAK
26 ansformed by E1A/Ras and generated tumors in immunodeficient hosts as efficiently as wild-type (WT) t
27 a protocol to engineer humanized bone within immunodeficient hosts, which can be adapted to study the
31 ha mutation; and hu cord blood-reconstituted immunodeficient, hu cytokine-secreting, mice that have l
33 elanoma growth in immunocompetent but not in immunodeficient (IFNgamma(-/-), nude, or CD8(-/-)) mice.
34 tes to these disappointing outcomes using an immunodeficient IL2 receptor gamma (IL2rgamma)-null mous
35 /-)) Ag-specific Tfh cells were used to help immunodeficient Il21r(-/-) B cells following T-dependent
36 ontrast to nonobese diabetic severe combined immunodeficient Il2rg(-/-) (NSG) mice, human NK cells in
39 ypes, including nonhematopoietic cells, into immunodeficient mice (lung-only mice) resulted in the de
40 t tumors resembling early-stage SCLC grew in immunodeficient mice after subcutaneous injection of PNE
42 s were transplanted under the KC of diabetic immunodeficient mice at a marginal dose (500 islet equiv
46 mal imaging was performed in severe combined immunodeficient mice bearing solid and disseminated MM t
48 oliferation in vitro or tumor progression in immunodeficient mice but completely impaired GBM progres
49 PV1/MusPV1) induces persistent papillomas in immunodeficient mice but not in common laboratory strain
50 eate primary gastrointestinal (GI) tumors in immunodeficient mice by tail-vein injection rather than
51 ng the (68)Ga radioisotope and injected into immunodeficient mice can be tracked in real time from th
54 an in vivo synthetic niche in the dermis of immunodeficient mice driving the differentiation of cDCs
56 y of TCR-transduced T cells was confirmed in immunodeficient mice engrafted with a human AML cell lin
60 Patient-derived xenograft tumours growing in immunodeficient mice exhibited enhanced hypoxia compared
61 nder the renal capsule of the left kidney in immunodeficient mice followed by the implantation of a t
63 transplanted into the subcutaneous space of immunodeficient mice generated fewer functional blood ve
69 and significantly prolonged the survival of immunodeficient mice implanted with the transformed HCD-
70 T cell activation when used to reconstitute immunodeficient mice in the presence of scurfy fetal liv
71 progenitor cells and reduced their growth in immunodeficient mice in vivo, in comparison with NIL alo
75 w humanized mouse model consisting of highly immunodeficient mice intrasplenically injected with peri
76 ovel preclinical in vivo model consisting of immunodeficient mice intrasplenically injected with peri
80 of CD4(+)CD45RB(hi)Nlrp12(-/-) T cells into immunodeficient mice led to more severe colitis and atop
81 landular transplantation of cultured MSCs in immunodeficient mice led to their engraftment in the inj
82 eekly injections of 1 mg kg(-1) of mRNA into immunodeficient mice maintain trough VRC01 levels above
83 orted that reconstitution of CD3+ T cells in immunodeficient mice mimics ART-induced bone loss observ
84 have focused on the historic development of immunodeficient mice over the last 2 decades, as well as
85 iviral MYC vector and then transplanted into immunodeficient mice produced a hierarchically organized
86 g high throughput TCRbeta CDR3 sequencing in immunodeficient mice receiving human hematopoietic stem
87 ers as fetal human thymus (HU THY) grafts in immunodeficient mice receiving the same human CD34(+) ce
88 had approximately equal abilities to infect immunodeficient mice reconstituted with a human hematopo
90 nsplantation into immunocompetent as well as immunodeficient mice resulted in a strong reduction of t
91 in human cancer cell lines xenografted into immunodeficient mice resulted in activation of canonical
92 antation of transduced FA CD34(+) cells into immunodeficient mice resulted in reproducible engraftmen
93 Transplantation of CYTH1-knockdown cells to immunodeficient mice resulted in significantly lower lon
94 NPM-ALK-transformed CD4+ T lymphocytes into immunodeficient mice resulted in the formation of tumors
95 c implant of CCA human cells in the liver of immunodeficient mice resulted in the release to serum of
96 f splenocytes and experiments in genetically-immunodeficient mice reveal the importance of both T and
97 ed with small hairpin RNA (shRNA)-STAT3 into immunodeficient mice revealed a decrease in the number o
98 e seminiferous tubules of germ cell-depleted immunodeficient mice revealed divergent fates of iPSCs p
100 alp hair follicles onto chemotherapy-treated immunodeficient mice serves as an excellent in vivo mode
101 esis that human cells grown as xenografts in immunodeficient mice should produce equivalent immunopep
102 n of day 20 CMs into the infarcted hearts of immunodeficient mice showed good engraftment, and echoca
103 transplantation of corrected WAS HSPCs into immunodeficient mice showed persistence of edited cells
104 te tumor xenografts in ovariectomized female immunodeficient mice supplemented with 17beta-estradiol.
105 gical tolerance unfold in mutant mice and in immunodeficient mice that received p53cKO-derived thymoc
106 was induced in human arteries engrafted into immunodeficient mice that were reconstituted with T cell
107 esponse of human hair follicles grafted onto immunodeficient mice to cyclophosphamide resembles the k
108 t diseases, followed by transplantation into immunodeficient mice to generate genetic models of clona
111 y positron emission tomography as well as in immunodeficient mice transplanted with human islets unde
112 nt donor cells were significantly reduced in immunodeficient mice transplanted with MF CD34(+) cell g
115 r radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-
116 g effect of hypoxia on tumor initiation into immunodeficient mice using human non-small lung carcinom
117 of CCA tumors subcutaneously implanted into immunodeficient mice was inhibited by 5-fluorouracil.
119 allergen-induced gut and lung inflammation, immunodeficient mice were engrafted with PBMCs from thes
121 M21 (human melanoma)-bearing severe combined immunodeficient mice were used for biodistribution, PET
122 ty and efficacy in targeting brain tumors in immunodeficient mice when the MLD was expressed within t
123 monstrated in human CD46 transgenic mice and immunodeficient mice with engrafted human CD34(+) cells
124 n the spinal cord and dorsal root ganglia of immunodeficient mice with higher efficacy than AAV2, 5,
125 third model was generated by reconstituting immunodeficient mice with human CD34+ hematopoietic stem
126 n HD glial chimeras by neonatally engrafting immunodeficient mice with mutant huntingtin (mHTT)-expre
128 metastasis, and mortality of severe combined immunodeficient mice xenografted with PC3 or DU145 cells
129 Subsequently, PET imaging was performed on immunodeficient mice xenografted with these cell lines.
130 HSCs with >6-month repopulating activity in immunodeficient mice) displayed rapid increases in activ
131 mice, immunocompetent, or in severe combined immunodeficient mice, and after treatment with an immuno
132 d human TECs, human thymic tissue grafted to immunodeficient mice, and murine fetal thymus organ cult
133 ient-derived RCC samples into the kidneys of immunodeficient mice, as well as the s.c. implantation f
134 antitumor activity in immunocompetent versus immunodeficient mice, demonstrating a contribution of th
136 myeloid cells in vitro and can also engraft immunodeficient mice, generating myeloerythoid and B-lym
138 Skin models, in culture and xenografts in immunodeficient mice, have potential for research on vir
139 t ZIKV infection in both immunocompetent and immunodeficient mice, highlighting the value of NS1 as a
140 studying human malignant and normal HSCs in immunodeficient mice, including newly developed mice for
141 ative capacity in either immune-competent or immunodeficient mice, indicating a critical need for imp
142 euroblastoma tumor engraftment and growth in immunodeficient mice, indicating an effect independent o
143 es decreased and was comparable to uptake in immunodeficient mice, indicating saturation of CD3 bindi
144 effect of DS-5272 is markedly attenuated in immunodeficient mice, indicating the critical impact of
145 in vivo human GBM xenograft experiments with immunodeficient mice, mAb treatment inhibited growth of
148 tive transfer experiments into tumor-bearing immunodeficient mice, NKG2Anull NK cells were significan
149 ng PARN mutations were xenotransplanted into immunodeficient mice, oral treatment with a repurposed P
152 tation of miR-377 silenced hCD34(+) cells in immunodeficient mice, promoting neovascularization (at 2
153 erved in wild-type mice and was abrogated in immunodeficient mice, suggesting that the antitumor acti
156 generate leukemia upon transplantation into immunodeficient mice, thus providing formal evidence tha
158 ong-term reconstitution when transplanted in immunodeficient mice, were present in the chorion from 1
159 andates awareness of replicating MuLV in NOD immunodeficient mice, which can significantly influence
160 erformed in tumour xenografts in 15 NCr nude immunodeficient mice, which were treated with either the
161 y, we unintentionally generated RV-resistant immunodeficient mice, which, we hypothesized, reflected
215 d/or injected into flanks of severe combined immunodeficient mice; xenograft tumor growth and metasta
218 otransplantation model in cytokine-humanized immunodeficient "MISTRG" mice that provides efficient an
219 n ECs lining human coronary artery grafts in immunodeficient mouse hosts by alloantibody and compleme
222 cells and promotes osteolysis in vivo in an immunodeficient mouse model of bone metastasis through u
223 of a DMD patient (mdcs) transplanted into an immunodeficient mouse model of DMD, we report that two n
225 Following inoculation of a highly sensitive immunodeficient mouse model, crucial immune parameters,
229 the number of TUNEL+ cells in non-dystrophic immunodeficient mouse muscles and it only slightly enhan
233 rial transfer was observed in vivo in an NSG immunodeficient mouse xenograft model and also occurred
234 ve activities in TSC2-deficient cells and an immunodeficient mouse xenograft model of lymphangioleiom
239 nes, and human B cell activation factor into immunodeficient NOD scid gamma (NSG) mice by the use of
243 D19(+) B cell population after transfer into immunodeficient NOD.Cg-Prkdc(scid) Il2rg(tm1wjl)/SxJ neo
245 abeled cell sorting and transplantation into immunodeficient NOD/SCID/interleukin 2 receptor gamma ch
246 ne on male nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice bearing human PSMA(+) PC
247 Human but not mouse islets transplanted into immunodeficient NSG mice effectively accumulate lipid dr
248 ells from giant cell arteritis patients into immunodeficient NSG mice engrafted with human arteries.
249 one marrow (BM) cells were transplanted into immunodeficient NSG mice to generate an immunocompetent
252 S/G2-phase human HSCs after engraftment into immunodeficient (NSG) mice, a phenotype that is associat
253 s (HSPCs) expressing MLL-AF9 or MLL-Af4 into immunodeficient NSGS mice, which strongly promote myeloi
257 g systemic injection of ICL-labeled cells in immunodeficient or immunocompetent mice, few cells arriv
258 is usually safe but cannot be given to many immunodeficient patients and retains the capacity to est
260 rvations support the concept that some DOCK8-immunodeficient patients have mutable mosaic genomes tha
262 nalizes more than 60 mutations identified in immunodeficient patients, as well as a large body of gen
263 ines are essential for disease prevention in immunodeficient patients, just as they are for healthy s
268 iated NOD2 mutations could cause a primarily immunodeficient phenotype by selectively impairing TLR4-
272 of SGM (e.g. FOXN1, RAG2, IL2RG, and PRKDC) immunodeficient rabbits, as well as multigenic mutant im
274 By serially transplanting hyperplasias into immunodeficient rag1 mutant zebrafish, we succeeded in l
278 vertheless, when adoptively transferred into immunodeficient Rai(+/+) mice, these cells promoted a mo
284 nctive B cell progeny when transplanted into immunodeficient recipients, supporting a two-pathway mod
288 racteristics were studied in severe combined immunodeficient (SCID) mice inoculated with activated hP
294 ll studied of these hosts, with a variety of immunodeficient strains available for various specific u
295 nd cellular vaccine responses in healthy and immunodeficient subjects and how that knowledge can then
299 dren (median age, 7.3 years), 59.2% severely immunodeficient, with suspected tuberculosis in Southeas