ライフサイエンスコーパス: immunodominant epitope

1 r of memory CD8 T cells (specific to the two immunodominant epitopes).

2 ation (uncontrolled antigen presentation and immunodominant epitopes).

3 the recombinant EspA filaments forming a new immunodominant epitope.

4 V-1 peptides detected revealed an additional immunodominant epitope.

5 ingle amino acid modification, I129V, in the immunodominant epitope.

6 the S protein (residues 528-635) is a major immunodominant epitope.

7 eactivity, suggesting the destruction of the immunodominant epitope.

8 cells also failed to induce tolerance to an immunodominant epitope.

9 mains, and there was no evidence of a single immunodominant epitope.

10 acterial activity while safely expelling the immunodominant epitope.

11 s approaching those of CTLp specific for the immunodominant epitope.

12 7-negative EL4 cells develop CTL only to one immunodominant epitope.

13 a vaccine expressing the same Ag without its immunodominant epitope.

14 he fate of this peptide from a cryptic to an immunodominant epitope.

15 s recognizing virion protein 22 aa 49-57, an immunodominant epitope.

16 Donors reacted to diverse immunodominant epitopes.

17 st both virally encoded and tumor-associated immunodominant epitopes.

18 tivity, Ins1 B5-14 and Ins1/2 A2-10 were the immunodominant epitopes.

19 is skewing of antibody responses to variable immunodominant epitopes.

20 n highly focused on a very limited number of immunodominant epitopes.

21 ar or higher avidity than those specific for immunodominant epitopes.

22 ation with T Ag-expressing cells lacking the immunodominant epitopes.

23 pe VII collagen, the domain known to contain immunodominant epitopes.

24 y when self-tolerance limits the response to immunodominant epitopes.

25 cept one of these regions was encoded within immunodominant epitopes.

26 ed from human and swine HEV contain the same immunodominant epitopes.

27 can distort the capture of the physiological immunodominant epitopes.

28 he size of the CD8(+) T cell response to two immunodominant epitopes.

29 an important influence on the generation on immunodominant epitopes.

30 esponse is to create vectors that lack these immunodominant epitopes.

31 ffectively compete with T cells specific for immunodominant epitopes.

32 oligoclonal and focused on a small number of immunodominant epitopes.

33 the cellular and humoral immune responses to immunodominant epitopes.

34 ng 22 T-cell epitopes, Aln g 1 contained two immunodominant epitopes.

35 ic mice that are centrally tolerant to these immunodominant epitopes.

36 y landscape in favor of MHC I complexes with immunodominant epitopes.

37 class II molecules and included most of the immunodominant epitopes.

38 ssed HLA class II molecules and knowledge of immunodominant epitopes.

39 le antigens may be biased towards conserved, immunodominant epitopes.

40 rnary epitopes and V1/V2-mediated masking of immunodominant epitopes.

41 a and directed against three promiscuous and immunodominant epitopes.

42 ered a fusion protein of mouse IgG1 with the immunodominant epitope 12-26 from bacteriophage lambda c

43 To identify immunodominant epitopes, 33 peptides overlapping human t

44 essive effector memory CTLs specific for the immunodominant epitope 40-48 of myelin oligodendrocyte g

45 Epitope mapping of LipC identified 6 immunodominant epitopes, 5 of which map to the exposed s

46 Nevertheless, a polymorphism in the immunodominant epitope #7 (S73T) showed a 56-99% reducti

47 Five immunodominant epitopes accounted for more than half of

48 the production of peptides encompassing the immunodominant epitope and destruction of the subdominan

49 c CD4+ T cells are directed against a single immunodominant epitope and exist independently of Ab res

50 may serve to amplify the CTL response to the immunodominant epitope and prevent the emergence of immu

51 r data indicate that E6 aa48-57 contains the immunodominant epitope and that a CRT/E6 DNA vaccine may

52 suggest that iB-1 is an immunogenic but not immunodominant epitope and that anti-iB-1 antibodies do

53 responses to rLACK are skewed away from the immunodominant epitopes and are diversified to include t

54 lt in impaired CD8 T cell responses to known immunodominant epitopes and decline in heterosubtypic im

55 Progress in defining the immunodominant epitopes and how neutralizing antibodies

56 nactivated SARS-CoV recognized the two major immunodominant epitopes and one antigenic site located a

57 Those moieties represent the immunodominant epitopes and the most functional ones.

58 eleted or mutated to alanine, eliminated the immunodominant epitope, and we used this information to

59 of memory CD8 T cells to only one of the two immunodominant epitopes, and p75R deficiency had a minim

60 t epitopes, the 32-kDa protein contained two immunodominant epitopes, and the 16-kDa protein containe

61 onymous/synonymous mutations and encompassed immunodominant epitopes, and their locations were not es

62 echanisms for class II-mediated selection of immunodominant epitopes are complex and differ for each

63 Immunodominant epitopes are few selected epitopes from c

64 Immunodominant epitopes are known to suppress a primary

65 Autoantigen-derived immunodominant epitopes are resistant to digestion by ca

66 eral blood of human subjects and to identify immunodominant epitopes associated with viral infection.

67 he Leishmania major LACK antigen contains an immunodominant epitope at amino acids 156 to 173 (LACK(1

68 ecombinant OGDC-E2 was judged to express the immunodominant epitope, because when sera from patients

69 This immunodominant epitope bound stably to DQ2.2.

70 he amplification of the CTL response to this immunodominant epitope, but also to the recognition of f

71 rove our ability to elicit antibodies to non-immunodominant epitopes by vaccination.

72 trates that a single amino acid change in an immunodominant epitope can eliminate an immune response

73 nduced CD8(+) T-cell responses against three immunodominant epitopes can increase the incidence of el

74 The immunodominant epitope, CII (186-192), contains a QGPRG

75 MBP residues 111-129 compose an immunodominant epitope cluster restricted by HLA-DRB1*04

76 nalysis revealed a minimal determinant of an immunodominant epitope, comprising critical residues at

77 at these responses are heterogeneous with no immunodominant epitopes consistently recognized.

78 Located within a single CP subunit is an immunodominant epitope consisting of residues 169 to 180

79 we have shown that the regions flanking the immunodominant epitope constitute a portable motif that

80 oci restricted the dominant regions, and the immunodominant epitopes could be predicted using bioinfo

81 and transient exposure of non-neutralizing, immunodominant epitopes could hinder the induction of br

82 57BL/6 mice, which are unable to present the immunodominant epitope, CSP-based vaccines did not confe

83 ed CD8+ T cells, including those recognizing immunodominant epitopes, decline with combination therap

84 Efficient presentation of an immunodominant epitope derived from glutamate decarboxyl

85 mice with bioactive CpG ODN combined with an immunodominant epitope derived from herpes simplex virus

86 lls indicated that nearly 20-fold more of an immunodominant epitope derived from kappa L chains was b

87 linical trial data in mice, we introduced an immunodominant epitope derived from ovalbumin (OVA; SIIN

88 DC increased cross-presentation of E75, the immunodominant epitope derived from the HER2 protein, an

89 Here, we have identified an immunodominant epitope derived from the S. typhimurium G

90 or memory CD4(+) T(EM) cells specific to two immunodominant epitopes derived from the HSV-1 tegument

91 tope V is weakly cross-presented relative to immunodominant epitopes derived from the same protein Ag

92 In this study, we show that two immunodominant epitopes derived from the tumor Ags (TAs)

93 on in a Japanese cohort, they included three immunodominant epitopes, emphasizing the contribution of

94 eceptor retinoid binding protein or with its immunodominant epitope encoded by residues 161-180.

95 unctionality, whereas those specific for the immunodominant epitope exhibit increased functionality i

96 We recently identified the immunodominant epitope for polyoma virus-specific CTL as

97 We previously identified the immunodominant epitope for polyoma virus-specific CTL in

98 This epitope has been termed the immunodominant epitope for the FVB/N mouse, but we propo

99 to 62 of Hsp20, which contained one or more immunodominant epitopes for each animal.

100 vant-free mix of three peptides that include immunodominant epitopes for gluten-specific CD4-positive

101 opulation of CD8(+) T cells specific for the immunodominant epitope formed by H-2Db and the influenza

102 Phosphocholine (PC) is the immunodominant epitope found on the surface of Streptoco

103 xicity against the immunizing peptides or an immunodominant epitope from an influenza recall antigen.

104 7BL/6 mouse, CD8(+) T cells specific for the immunodominant epitope from glycoprotein B maintain func

105 ers containing a peptide corresponding to an immunodominant epitope from human GAD65 were used to ana

106 d carboxyl-terminal extension containing the immunodominant epitope from influenza hemagglutinin anti

107 The in vitro binding of an immunodominant epitope from the myelin basic protein (MB

108 approximately 85% of cells specific for the immunodominant epitope from the viral matrix (M) protein

109 and memory TCR repertoires for each of three immunodominant epitopes from lymphocytic choriomeningiti

110 Unlike most pathogens, many of the immunodominant epitopes from Mycobacterium tuberculosis

111 s on and responds to very few representative immunodominant epitopes from pathogenic insults.

112 topes that can be as strong as those seen in immunodominant epitopes from the "conventionally process

113 II-restricted processing and presentation of immunodominant epitopes from the major house dust mite a

114 MEFA-6) which incorporates all of the major immunodominant epitopes from the seven functional region

115 D8(+) T cell responses of cattle against two immunodominant epitopes from Theileria parva (Tp1(214-22

116 human cells specific for OspA(165-184), the immunodominant epitope, from five DRB1*0401(+) patients,

117 The immunodominant epitope, gD (362-370), was identified wit

118 blood and mucosal tissues, with responses to immunodominant epitopes generally shared by both sites;

119 The four immunodominant epitopes have been tested for immunogenic

120 thermore, this vaccination approach subverts immunodominant epitope hierarchies by enhancing response

121 Immunodominant epitopes highly conserved across genotype

122 T cell tolerance to the H-2-D(b)-restricted immunodominant epitope I of T Ag by 6 mo of age, before

123 We found a single, highly immunodominant epitope in 46% (23/50) of the donors.

124 the CD8(+) T cell response specific for the immunodominant epitope in C57BL/6 mice, derived from gly

125 nocytogenes or vaccinia virus expressing the immunodominant epitope in C57BL/6 mice.

126 We have identified an immunodominant epitope in citrullinated alpha-enolase, t

127 mpatibility complex (MHC) protein I-Au is an immunodominant epitope in experimental autoimmune enceph

128 e early CTL response was focused on a highly immunodominant epitope in gp 160, there was rapid elimin

129 similar, indicating that MT(389-397) is the immunodominant epitope in H-2k mice.

130 These results indicate that the immunodominant epitope in PLA2R is exclusively located i

131 n the brain even when those reactive with an immunodominant epitope in Tat are lost from the rest of

132 121-130 presented in the context of Db is an immunodominant epitope in TMEV infection and that the fr

133 ts to the importance of internal residues as immunodominant epitopes in (1-->2)-beta-mannans and to t

134 ein specifically recognized multiple, unique immunodominant epitopes in autologous tumor idiotype.

135 Whether the immunodominant epitopes in B95.8 are shared in virus fro

136 inst factor VIII are mainly directed against immunodominant epitopes in C2, A3, and A2 domains.

137 We studied the CD8(+) T cell response to six immunodominant epitopes in five HIV-infected subjects us

138 es, and HLA tetramer binding against defined immunodominant epitopes in gag, pol, env, and nef as wel

139 ein (PLP) 175-192, that are considered to be immunodominant epitopes in HLA-DR4 individuals.

140 ents termed nanoallergens, we identified two immunodominant epitopes in peanuts that were common in a

141 peptide pool demonstrates a pivotal role for immunodominant epitopes in the generation of a clonal re

142 These findings implicate immunodominant epitopes in the pathology of ANCA-associa

143 lass I (MHC-I) molecule Mamu-B*08 that binds immunodominant epitopes in Vif and Nef.

144 Furthermore, CTLs to some of the immunodominant epitopes involve highly conserved T cell

145 core shells with an antibody specific to the immunodominant epitope is compared to the constructs wit

146 dicated that, like serum autoantibodies, the immunodominant epitope is directed against the inner lip

147 The immunodominant epitope is DRB1-restricted and was observ

148 tive Darwinian selective pressure against an immunodominant epitope is presented.

149 d modulation of effector T cells specific to immunodominant epitopes is a central issue in autoimmune

150 The PPI/PI immunodominant epitope LALEGSLQK was localized at the C-

151 The mapped 12-amino acid immunodominant epitope lies within a "hinge" region betw

152 EBA autoantibodies recognize four major immunodominant epitopes localized within the amino-termi

153 Two major immunodominant epitopes located in the C-terminal region

154 ain these epitopes but lack the variable and immunodominant epitopes located in the globular head of

155 g without limiting virus viability, and also immunodominant epitopes located in variable regions.

156 ominant epitope and prevent the emergence of immunodominant epitope-loss viruses and virus-induced tu

157 This immunodominant epitope may be a uniquely accessible surf

158 compared with uncomplexed trimers.IMPORTANCE Immunodominant epitopes may suppress immune responses to

159 according to the binding motif of the human immunodominant epitope MBP 85-99 and the binding pockets

160 Its immunodominant epitope, MBP 85-99, forms a complex with

161 ern that the combination of several normally immunodominant epitopes might result in a new hierarchy

162 We show that ANT1 encompasses multiple immunodominant epitopes (namely, ANT1 21-40, ANT1 31-50,

163 A single Db-restricted immunodominant epitope (NP(366)) was previously known in

164 amma-producing CD8+ T cells specific for the immunodominant epitope NS3-1073 in 26 of 30 mice (86%) t

165 s optica (NMO) patients, which recognize the immunodominant epitope of aquaporin-4, exhibit Th17 pola

166 y using a human T-cell line specific for the immunodominant epitope of Bet v 1 and in vivo in an adju

167 mer covalently loaded with OspA(164-175), an immunodominant epitope of Borrelia burgdorferi.

168 Mapping of the immunodominant epitope of E6 revealed that an E6 peptide

169 Specifically, an immunodominant epitope of EV71 that maps to the virus ca

170 nerated TCR transgenic NOD mice for a second immunodominant epitope of GAD65, peptide 206-220 (G206).

171 Both TCR are responsive to an immunodominant epitope of glutamic acid decarboxylase 65

172 t viral replication through targeting of the immunodominant epitope of group-associated antigen (Gag)

173 Interestingly, the display of the immunodominant epitope of HEL, 106-116/E(d), and of a do

174 terminal residues, Trp62/63, which flank the immunodominant epitope of hen egg lysozyme (HEL 52-61),

175 nses to the COOH-terminal PFR of the H-2A(k) immunodominant epitope of hen egg lysozyme (HEL) 52-61.

176 HLA-DR53 and H-2Ek, extensive mimicry of the immunodominant epitope of HLA-DR53 by several carcinogen

177 ctively to a synthetic peptide containing an immunodominant epitope of HuCOAg (peptides 69-83).

178 racterisation of the genetic basis of a key, immunodominant epitope of meningococcal LPS.

179 me(v+/-)) and B10.PL wild-type mice with the immunodominant epitope of myelin basic protein (MBP Ac1-

180 on the nature of the anchor residues of the immunodominant epitope of myelin basic protein (MBP) 85-

181 Amino acid residues 111-129 represent an immunodominant epitope of myelin basic protein (MBP) in

182 An immunodominant epitope of myelin basic protein (MBP), VH

183 , we demonstrated that analog peptides of an immunodominant epitope of myelin basic protein (residues

184 The immunodominant epitope of OspA for T helper cells was id

185 The immunodominant epitope of OspA in the context of HLA-DRB

186 tested a "worst case" scenario in which the immunodominant epitope of OVA (SIINFEKL) and its in vitr

187 ronal hnRNP A1 is contained within the human immunodominant epitope of tax and suggests that molecula

188 f CD8(+) T cells that recognize the Tax11-19 immunodominant epitope of Tax protein expressed by human

189 nia in which antibody is directed against an immunodominant epitope of the beta3 (glycoprotein IIIa [

190 t recombinant L. monocytogenes expressing an immunodominant epitope of the LCMV glycoprotein (GP33) w

191 h frequency of CD4+ T cells specific for the immunodominant epitope of the viral hemagglutinin (HA) p

192 In addition to an immunodominant epitope of the viral nucleoprotein (NP) t

193 CD8(+) T cell immunodominant epitopes of alpha-NAC were mapped by appl

194 These results demonstrate that immunodominant epitopes of carefully selected M. tubercu

195 cted autoreactive CD4(+) T cells recognizing immunodominant epitopes of Dsg3 initiate the production

196 s of eight SMS patients recognised different immunodominant epitopes of GAD65 compared with T cells f

197 tigen receptor (TCR) specific for one of the immunodominant epitopes of GAD65, peptide 286-300 (G286)

198 Determination of immunodominant epitopes of MHC class I-restricted self-A

199 the antibody response and suggested that the immunodominant epitopes of OspC reside in the variable d

200 tive immunity is not necessarily directed at immunodominant epitopes of pathogens and may be improved

201 Interestingly, the immunodominant epitopes of PDC-E2, BCOADC-E2, and OGDC-E

202 ead consistent with periodic turnover of the immunodominant epitopes of PfEMP1 associated with severe

203 ells specific for the three H2(b)-restricted immunodominant epitopes of T-Ag.

204 The immunodominant epitopes of the 30- and 32-kDa proteins i

205 The immunodominant epitopes of these major extracellular pro

206 used overlapping sets of peptides to map the immunodominant epitopes of this autoantigen.

207 ully identified the physiologically selected immunodominant epitopes of two model antigens: hemagglut

208 V)-specific CD8 T cells recognize a strongly immunodominant epitope on glycoprotein B (gB498) and can

209 ce, activated CD8(+) T cells specific for an immunodominant epitope on HSV-1 glycoprotein B (gB-CD8 c

210 ice, half of these cells are specific for an immunodominant epitope on HSV-1 glycoprotein B, whereas

211 that this immune response is directed at an immunodominant epitope on the bacterial surface.

212 dy the specificity of the CTL response to an immunodominant epitope on the dengue virus NS3 protein.

213 Antibodies reactive with an immunodominant epitope on the F glycoprotein of this vir

214 I occurs as a result of the expression of an immunodominant epitope on the P2 molecule.

215 E-1 TAAs to investigate presentation of this immunodominant epitope on the surface of a variety of ca

216 The BclA protein is the immunodominant epitope on the surface of Bacillus anthra

217 maintain a 1:1 ratio of cells recognizing an immunodominant epitope on viral glycoprotein B (gB498-50

218 gineered FVIII molecules has further defined immunodominant epitopes on FVIII and may provide a thera

219 lergy is a common phenomenon that can reveal immunodominant epitopes on major allergenic proteins.

220 chronic graft loss; thus, identification of immunodominant epitopes on major histocompatibility comp

221 ker of HIV-1-ITP elicited due to exposure of immunodominant epitopes on talin-H as a result of a dise

222 nal and monoclonal antibodies indicated that immunodominant epitopes on the capsid protein as well as

223 In this study, we identified two major immunodominant epitopes on the M protein located in the

224 209 through 276, indicating that one or more immunodominant epitopes on Topo I is located between ami

225 rating encephalitogenic T cells specific for immunodominant epitopes on various myelin proteins that

226 s infection is often focused on one or a few immunodominant epitopes, one approach to circumvent this

227 Two immunodominant epitopes-one to precursor membrane protei

228 e lambda repressor cI sequence p1-102 or its immunodominant epitopes (p12-26, p73-88) can be elicited

229 of MHC class I molecules in complex with two immunodominant epitopes (PA(224-233)/D(b) and PB1(703-71

230 Specifically, the amino-terminal immunodominant epitope, peptide 5 (P5), stimulates stron

231 -) mice were expanded in the presence of the immunodominant epitope present in the MHV transmembrane

232 line immunodeficiency virus (FIV) comprising immunodominant epitopes present in the third variable do

233 ered antigen processing and the hierarchy of immunodominant epitope presentation.

234 nown to bind to M3 molecules, fMIGWII is the immunodominant epitope presented by M3 during infection

235 unodominance effect, whereby the presence of immunodominant epitopes prevents recognition of nondomin

236 ed target cells coated with two of the three immunodominant epitopes previously defined for LCMV (gly

237 Among the HPV6-specific sera there was no immunodominant epitope recognized by all sera.

238 An immunodominant epitope recognized by anti-topo I autoant

239 In addition, 26D1 epitope is immunodominant epitope recognized by both antibodies eli

240 We now show that the immunodominant epitope recognized by CD4+ Th cells from

241 We previously identified TB10.4(20-28) as an immunodominant epitope recognized by H2-K(d)-restricted

242 specific for listeriolysin O (LLO)91-99, the immunodominant epitope recognized by H2-Kd-restricted T

243 Since there is not one immunodominant epitope recognized by most hosts, strateg

244 nd the PDTRP fragment, which is a well-known immunodominant epitope recognized by several anti-MUC1 m

245 The mutated PPP1R3B peptide represents the immunodominant epitope recognized by tumor-reactive T ce

246 entameric B subunit of CT (CTB) contains the immunodominant epitopes recognized by antibodies that ne

247 virus (HIV) escape mutations often arise in immunodominant epitopes recognized by MHC class I allele

248 Here, we identified the immunodominant epitope region in PLA2R by probing isolat

249 elated with overall sequence homology, and 2 immunodominant epitope regions of Phl p 12 were identifi

250 rity of dominant over subdominant responses, immunodominant epitopes represent the preferred vaccine

251 Eight (72%) of 11 recognized > or =1 immunodominant epitope, representing either a new or an

252 The elimination of the immunodominant epitope response also eliminated the resp

253 or residue, thereby abrogating activation of immunodominant epitope responses.

254 e presented by this allele, and suggest that immunodominant epitopes restricted by common HLA alleles

255 Mutational analysis of the immunodominant epitopes revealed that single amino acid

256 hat memory CD8 T cells specific for a single immunodominant epitope (S436 or S525) substantially prot

257 This report, therefore, indicates that immunodominant epitopes should be defined, not only by t

258 K288S/Y176F, a variant mutated in one of the immunodominant epitopes, showed reduced antigenicity.

259 The vaccine-elicited immunodominant epitope-specific CD8(+) T lymphocyte resp

260 The availability of immunodominant epitope-specific CTL capable of recognizi

261 sed by virus isolates to mutate away from an immunodominant epitope-specific CTL response are not wel

262 oss-presentation coupled with competition by immunodominant epitope-specific T(CD8) contributes to th

263 These results showed that P5 contains an immunodominant epitope specifically associated with DTH

264 of the previously defined HLA-A2-restricted immunodominant epitope SSX-2(41-49).

265 ur-TCR-Tg]) expressing a TCR recognizing the immunodominant epitope (Sur20-28) of murine survivin dur

266 duced frequency of T cells responding to the immunodominant epitope Talpha146-162 indicating a degree

267 suggesting that circulating viruses may lack immunodominant epitopes targeted through HLA-A2.

268 s revealed flanking residues proximal to the immunodominant epitope that increased the production and

269 ctural and immunobiological definition of an immunodominant epitope that is a candidate immunogen for

270 N specifically inhibited the response to two immunodominant epitopes that are known to be dependent o

271 mor cells is to identify and slightly modify immunodominant epitopes that elicit T-cell responses.

272 Moreover, the immunodominant epitopes that were most discriminatory be

273 thogen has made it difficult to characterize immunodominant epitopes that would allow the identificat

274 The 30-kDa protein contained nine immunodominant epitopes, the 32-kDa protein contained tw

275 at Cas9 protein can be modified to eliminate immunodominant epitopes through targeted mutation while

276 e was shifted from the previously identified immunodominant epitope to a novel epitope when the antig

277 with the non-immunodominant peptide enabled immunodominant epitopes to induce T-cell activation (p=0

278 ocytes to secrete cytokines or present viral immunodominant epitopes to virus-specific T cells.

279 jor histocompatibility complex (MHC) class I immunodominant epitopes using an overlapping peptide scr

280 We identified four immunodominant epitopes using synthetic peptides, and ma

281 dent increase in the surface exposure of the immunodominant epitope (V86-T98) as determined by antibo

282 iviral CD8 T cell responses against the TMEV immunodominant epitope VP2(121-130), with functional imp

283 An immunodominant epitope, VV-e7r130, did not generate cros

284 T-cell IFN-gamma immunity to OprF and its immunodominant epitopes was characterized.

285 the number of mutations within HBV core gene immunodominant epitopes was lower at TW28 and was negati

286 T-cell response directed against the single immunodominant epitope, we identify the sequence feature

287 ost and parasite may be responsible for this immunodominant epitope, we screened for antibody-reactiv

288 Antibodies specific for the immunodominant epitope were raised in rabbits or were pu

289 Specific responses against an immunodominant epitope were seen using IFN-gamma ELISPOT

290 human leukocyte antigen (HLA) restriction of immunodominant epitopes were defined using HLA class II

291 One to 3 major cN1A immunodominant epitopes were identified.

292 Several minor immunodominant epitopes were reactive with about 50% of

293 Immunodominant epitopes were the most efficacious in lon

294 epitopes are Tc2, in contrast to CTL for the immunodominant epitope, which are of the Tc1 type.

295 Antigenic site A includes most immunodominant epitopes, while antigenic site G shifted

296 clonal, polymeric IgA antibody that binds an immunodominant epitope within the O-antigen (O-Ag) compo

297 e mechanisms that determine the selection of immunodominant epitopes within complex protein antigens

298 We identified novel CD4- and CD8-restricted immunodominant epitopes within NS6 and VP1 antigens.

299 designated as pML-MIT3, that coexpresses the immunodominant epitopes within the three distinct lipoyl

300 n, and neuraminidase can easily mutate their immunodominant epitopes without impacting fitness.