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1 ity influenced by intrinsic factors like the immunoglobulin isotype.
2 genetic manipulation in PCs in vivo, across immunoglobulin isotypes.
3 ibody maturation and expression of different immunoglobulin isotypes.
4 lasma cells in vivo, without affecting other immunoglobulin isotypes.
5 center formation and production of secondary immunoglobulin isotypes.
6 proliferate and to switch from IgM to other immunoglobulin isotypes.
7 total B cells, plasmablasts, and plasmablast immunoglobulin isotypes.
8 dose 2 in both saliva and GCF for all three immunoglobulin isotypes.
9 or to mucosal immunization can influence the immunoglobulin isotype and specificity of the host humor
11 ) is the predominant M. catarrhalis-specific immunoglobulin isotype and that the sputum IgA contains
12 ing with significant increased levels of all immunoglobulin isotypes and anti-DNA antibodies in serum
13 e Th2-type pattern as judged by the ratio of immunoglobulin isotypes and interleukin-4 cytokine level
14 ct was associated with reduced TH2-dependent immunoglobulin isotypes and markedly diminished neutrali
15 acterized by impaired production of switched immunoglobulin isotypes and normal or elevated IgM level
16 effect on the primary induction of anti-CpsB immunoglobulin isotypes and on the ability to induce ant
18 pectra of plasma cells producing the various immunoglobulin isotypes, and the frequencies of virus-sp
19 widespread variation in the levels of serum immunoglobulin isotypes as well as in the percentages an
20 sts that Abs of the IgA class-the archetypal immunoglobulin isotype at mucosal sites -may synergize w
22 at ICOS-/- mice exhibit profound deficits in immunoglobulin isotype class switching, accompanied by i
25 ells switch production from IgM/IgD to other immunoglobulin isotypes, enabling them to mount an effec
27 -up of allergen-specific B cells in terms of immunoglobulin isotype expression, plasmablast different
28 mmunoglobulin A (IgA) is the major secretory immunoglobulin isotype found at mucosal surfaces, where
32 factors such as M protein concentration and immunoglobulin isotype, identify a group of individuals
33 among the 10 most dominant BCR clones of any immunoglobulin isotype (IgA, IgD, IgM, and IgG) in blood
34 baseline levels of the Th2-controlled serum immunoglobulin isotypes, IgE and IgG1, were also selecti
36 asal, total, and Betula verrucosa 1-specific immunoglobulin isotypes; immunoglobulin free light chain
38 Immunoglobulin A (IgA) is the predominant immunoglobulin isotype in mammals, primarily secreted at
39 ounced dominance of secretory IgA over other immunoglobulin isotypes in human saliva, tears, milk, an
40 alysis was used to study the distribution of immunoglobulin isotypes in paired preacquisition and pos
41 onsequences of a lack of production of other immunoglobulin isotypes in patients with HIgM syndrome.
43 re deficiency in the production of secondary immunoglobulin isotypes including IgG1, IgG2a, IgG2b, Ig
44 observation suggests that specialization of immunoglobulin isotypes into mucosal and systemic respon
45 s to engage the Fc-mediated functions of all immunoglobulin isotypes is an appealing strategy to furt
49 ing that paradigm, here we show that IgT, an immunoglobulin isotype of unknown function, acts like a
52 regulation of T(H)2 responses, IL4-dependent immunoglobulin isotype production, and tissue lesions wi
57 s coordinates the immune response, including immunoglobulin isotype switch and Fas-mediated apoptosis
58 responses, B cells are driven to undergo an immunoglobulin isotype switch, shifting from IgM to IgE
59 analyses confirmed the known role of AID in immunoglobulin isotype switching and also demonstrated f
61 IgM syndrome) is characterized by failure of immunoglobulin isotype switching and severe defects of c
62 B cells have undergone comparable levels of immunoglobulin isotype switching and somatic hypermutati
63 feration and guide their differentiation and immunoglobulin isotype switching by delivering contact-d
65 per-IgM (HIGM1), characterized by failure of immunoglobulin isotype switching, is caused by mutations
66 Protection from viral infections depends on immunoglobulin isotype switching, which endows antibodie
71 neity within and across LCLs with respect to immunoglobulin isotype; virus-modulated host pathways in
72 f expressing surface IgM and secreting other immunoglobulin isotypes were vulnerable to lethal infect
75 was also evaluated for detection of multiple immunoglobulin isotypes, with successful detection of Ig