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1 The RhoA-binding site was mapped to the Trio immunoglobulin-like domain.
2 e in the Trk receptors resides in the second immunoglobulin-like domain.
3 beta-propeller architecture and a C-terminal immunoglobulin-like domain.
4 nalogous region of UL18 using its N-terminal immunoglobulin-like domain.
5 l describes the aggregation of Titin I27, an immunoglobulin-like domain.
6 ranslational folding on the ribosome of this immunoglobulin-like domain.
7 to residues 71 to 289, a region including an immunoglobulin-like domain.
8 egulate Trio localization via binding to the immunoglobulin-like domain.
9 eptor, Flt-1 (or VEGFR-1), consists of seven immunoglobulin-like domains.
10 MHVR and Bgp1(b) comprised of the first two immunoglobulin-like domains.
11 elf-aggregate but did not bind to any of the immunoglobulin-like domains.
12 plasmic chaperones that are comprised of two immunoglobulin-like domains.
13 coprotein consisting of 318 aa including two immunoglobulin-like domains.
14 g" structure likely representing consecutive immunoglobulin-like domains.
15 molecular mass proteins containing bacterial immunoglobulin-like domains.
16 l missense variants within the extracellular immunoglobulin-like domains.
17 titin and most likely involves unfolding of immunoglobulin-like domains.
18 riking resemblance to the all-beta Greek key immunoglobulin-like domains.
19 istinctive bend between the second and third immunoglobulin-like domains.
20 inhibitory immunoreceptors that bear C2-type immunoglobulin-like domains.
21 a second cysteine-rich motif followed by two immunoglobulin-like domains.
24 Here, we found that leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is highly expresse
25 receptor antagonist leucine-rich repeats and immunoglobulin-like domains 1 (Lrig1), for further study
26 udy, we used Lrig1 (leucine-rich repeats and immunoglobulin-like domains 1) gene to label tissue-resi
28 iant of FGF receptor 1 (FGFR1) consisting of immunoglobulin-like domains 2 (D2) and 3 (D3) has been d
29 2 complexed with the ligand binding domains (immunoglobulin-like domains 2 [D2] and 3 [D3]) of FGF re
30 in LRIG2, encoding leucine-rich repeats and immunoglobulin-like domains 2, a protein implicated in n
31 , heparanase 2, and leucine-rich repeats and immunoglobulin-like domains-2 (LRIG2), which is mutated
34 t of several different species revealed that immunoglobulin-like domain 4 is the most conserved extra
35 iated molecule"), contains two extracellular immunoglobulin-like domains, a transmembrane domain, and
36 edicted protein containing two extracellular immunoglobulin-like domains, a transmembrane segment, an
37 The second domain is close to the second immunoglobulin-like domain (amino acid residues 342-394)
38 kDa transmembrane glycoprotein with a single immunoglobulin-like domain and a cytoplasmic tail contai
39 e protein that contains a novel six-cysteine immunoglobulin-like domain and a mucin domain; it is nam
40 p combines with part of the C-Lip to form an immunoglobulin-like domain and the remaining C-Lip forms
42 ansmembrane protein with three extracellular immunoglobulin-like domains and a cytosolic tail contain
43 plasma membrane glycoprotein containing two immunoglobulin-like domains and a single charge-containi
44 dothelial cell-specific receptors with seven immunoglobulin-like domains and a split kinase domain.
46 consists of an extended arrangement of three immunoglobulin-like domains and homodimerizes via a netw
47 hydrophobic interface between the two C2-set immunoglobulin-like domains and parallel pairing of thei
48 t has not been reported in tandem repeats of immunoglobulin-like domains and that is presumably conse
49 riant of human peroxidasin 1 comprising four immunoglobulin-like domains and the catalytically active
50 rane proteins that contain two extracellular immunoglobulin-like domains and therefore belong to this
51 f a putative extracellular segment with five immunoglobulin-like domains and three fibronectin III-li
52 he predicted beta-strand c and d of hIL-18BP immunoglobulin-like domain, and most had hydrophobic sid
53 threonine kinase domain, two SH3 domains, an immunoglobulin-like domain, and spectrin-like repeats.
55 ess, whereas sequences in or near the fourth immunoglobulin-like domain are required for interaction
56 All methods indicate that the extracellular immunoglobulin-like domains are monomeric in solution an
58 ke related immune receptors, GPVI contains 2 immunoglobulin-like domains arranged in a perpendicular
59 r graphics models of the human TrkA and TrkC immunoglobulin-like domains as a guide, the residues inv
60 LT-1 extracellular domain, suggest that this immunoglobulin-like domain autonomously plays an as yet
63 of all three domains belongs to the I-set of immunoglobulin-like domains, but shows several unusual f
64 Here, we have evaluated three mutations in immunoglobulin-like domains C1 (P161S, Y237S) and C2 (P3
65 ular fragment of TLT-1 consists of a single, immunoglobulin-like domain connected to the platelet cel
66 mplications for the role of A1BG and related immunoglobulin-like domain containing proteins in cancer
67 lipoprotein remnant receptor family known as immunoglobulin-like domain containing receptor 1 (ILDR1)
68 ILDR1 encodes the evolutionarily conserved immunoglobulin-like domain containing receptor 1, a puta
70 mbrane glycoprotein, with four extracellular immunoglobulin-like domains containing three intrachain
71 ncluding a family of leucine-rich repeat and immunoglobulin-like domain-containing protein (LINGO) su
72 fected the content of beta-lactoglobulin II, immunoglobulin-like domain-containing protein, interfero
73 f these deviations in the sequences of other immunoglobulin-like domain-containing receptors may help
74 cterium D. radiodurans shows similarities to immunoglobulin-like domain-containing S-layers from mono
76 This molecule contains four tandem external immunoglobulin-like domains (D1-D4), a transmembrane dom
81 g site on the apical surface between the two immunoglobulin-like domains (D1D2) of the receptor and s
82 lar portion of the protein contains a single immunoglobulin-like domain displaying 46% sequence ident
85 nal actin-binding domain and 24 filamin-type immunoglobulin-like domains (FLN) that form tail-to-tail
86 f 528 amino acids and contains three C2-type Immunoglobulin-like domains followed by one fibronectin
87 with an extracellular region composed of two immunoglobulin-like domains followed by two fibronectin
89 clude the first description of an N-terminal immunoglobulin-like domain, found on the p40 subunit.
90 hicken CAR, or with the heterologous type C2 immunoglobulin-like domain from IgSF11, another IgSF mem
91 in malignant transformation, we removed two immunoglobulin-like domains from the extracellular domai
93 ker between the IgII and IgIII extracellular immunoglobulin-like domains, have been documented in mor
94 [HveC(143t)], two [HveC(245t)], or all three immunoglobulin-like domains [HveC(346t)] of the extracel
96 inly of three segment types: serially linked immunoglobulin-like domains (Ig segments), interrupted b
97 ure of the agrin-responsive first and second immunoglobulin-like domains (Ig1 and Ig2) of the MuSK ec
98 sialylation of the N-glycans on the adjacent immunoglobulin-like domain (Ig5), and acidic residues on
100 nd IIIc, which form the extracellular, third immunoglobulin-like domain (IgIII) and adjacent linker r
102 adhesion role fulfilled by its extracellular immunoglobulin-like domain (IgMPZ), which oligomerizes.
103 The extracellular domain of Tvc contains two immunoglobulin-like domains, IgV and IgC, which presumab
104 engage a conserved hydrophobic groove in the immunoglobulin-like domain III (D3) of the "c" splice is
106 ing exons encoding the COOH-terminal half of immunoglobulin-like domain III and the transmembrane dom
107 otein containing leucine-rich repeats and an immunoglobulin-like domain in its extracellular region,
109 d by six leucine-rich repeat domains and one immunoglobulin-like domain in their extracellular moieti
111 eptor tyrosine kinase that consists of seven immunoglobulin-like domains in its extracellular portion
112 s in or near the first of four extracellular immunoglobulin-like domains in MuSK are required for agr
113 epsilon 3 and C epsilon 4 in IgE and the two immunoglobulin-like domains in the alpha-chain of Fc eps
114 CAM), a transmembrane glycoprotein with four immunoglobulin-like domains in the murine biliary glycop
115 , both elastin and HTE bind to the same LigB immunoglobulin-like domains, including LigBCon4, LigBCen
116 ot observed with Trio constructs lacking the immunoglobulin-like domain, indicating that RhoA acts to
117 arge modular protein composed mainly of many immunoglobulin-like domains, is a potent cross-linker of
118 unoglobulin-related receptors (KIR) with two immunoglobulin-like domains (KIR2D) modulate the lysis o
119 in (IL)-1 receptors with three extracellular immunoglobulin-like domains, limited homology (28%), and
121 involve different orientations of the outer immunoglobulin-like domains, mediated by a very flexible
124 monstrated that seven amino acids within the immunoglobulin-like domain of hIL-18BP were important fo
126 rmed dimers, suggesting a role for the third immunoglobulin-like domain of HveC in oligomerization.
127 in the coding region of the first N-terminal immunoglobulin-like domain of ICAM-1, present at high fr
128 three-dimensional model of the extracellular immunoglobulin-like domain of ICOS was used to map the r
130 sMHVR-Ig, which comprised the virus-binding immunoglobulin-like domain of MHVR fused to the Fc porti
132 udies show that a small portion of the first immunoglobulin-like domain of PVR contacts viral residue
133 of the LigA repeat region was limited to an immunoglobulin-like domain of the bacterial intimin bind
134 inserts into a hydrophobic pocket within the immunoglobulin-like domain of the GDI molecule leading t
138 affecting a conserved residue in the second immunoglobulin-like domain of titin, was introduced in a
139 rystal structure of PlGF bound to the second immunoglobulin-like domain of VEGFR1 at 2.5 A resolution
140 an be applied in the structure prediction of immunoglobulin-like domains of diverse modular proteins.
141 indicate that 1C3 inhibits clustering of the immunoglobulin-like domains of GPVI on collagen/CRPs, a
142 stigating the role of cysteine proteases and immunoglobulin-like domains of gram-positive and -negati
145 e crystal structures of the first and second immunoglobulin-like domains of the Drosophila type IIa r
146 All SynCAM genes encode proteins with three immunoglobulin-like domains of the V-set, C1-set, and I-
148 cellular region of KDR is comprised of seven immunoglobulin-like domains, of which the first three ha
153 ns comprising its extracellular portion, the immunoglobulin-like domain proximal to the membrane (Trk
154 an antagonist that interacts with the fourth immunoglobulin-like domain reduced LTP when applied befo
155 truncated form of TRKB containing the second immunoglobulin-like domain (residues 248-398) was expres
156 s of two main segment types: serially linked immunoglobulin-like domains (tandem Ig segments) interru
157 s implies that the amino acids in the second immunoglobulin-like domain that determine Trk specificit
158 egulin-1 form has a distinct heparin-binding immunoglobulin-like domain that enables it to adhere to
160 inal intracellular domain and the N-terminal immunoglobulin-like domains that are involved in Neo1 bi
162 ue to the high levels of immunoglobulins and immunoglobulin-like domains that arise during tumor deve
163 mbrane protein containing five extracellular immunoglobulin-like domains that is structurally related
164 unique inter-chain crystallization of folded immunoglobulin-like domains that resists inter-chain sli
165 mino acids at corresponding positions in its immunoglobulin-like domain, the exceptions being the con
166 ed that siglec-5 contains four extracellular immunoglobulin-like domains, the N-terminal two of which
167 spite previous assignment to the C2 class of immunoglobulin-like domains, the structure of IgD1 revea
168 e complex shows how AlkC uses unique HLR and immunoglobulin-like domains to induce a sharp kink in th
169 racellular domain of KIM-1 is composed of an immunoglobulin-like domain topping a long mucin-like dom
171 ain an extracellular region comprising three immunoglobulin-like domains (V-set amino-terminal domain
172 tructure shows that s-IL1R consists of three immunoglobulin-like domains which wrap around IL-1beta i
173 mum set of residues in the human TrkC second immunoglobulin-like domain, which does not bind nerve gr
175 ving the major beta sheets of the respective immunoglobulin-like domains with poor shape complementar
176 m Ig segments (consisting of serially linked immunoglobulin-like domains) with the unique PEVK segmen
177 spectroscopy, multiple states accessed by an immunoglobulin-like domain within a tandem repeat protei