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1 aid in identifying subtypes more amenable to immunomodulation.
2 anisms: malignant cell killing and TAM-based immunomodulation.
3 variety of homeostatic functions, including immunomodulation.
4 imates in the setting of clinically relevant immunomodulation.
5 scale that provides new insights into viral immunomodulation.
6 the level of these antibodies was lowered by immunomodulation.
7 genesis of severe pneumonia and a target for immunomodulation.
8 SHED-mediated osteogenic differentiation and immunomodulation.
9 19 genes associated with tissue tropism and immunomodulation.
10 ng cytokine partial agonists for therapeutic immunomodulation.
11 esent therapeutic targets for anti-CD132 mAb immunomodulation.
12 otential as an easily modifiable mediator of immunomodulation.
13 lecule has been shown to provide therapeutic immunomodulation.
14 nt, with further evidence of strain-specific immunomodulation.
15 for antimetabolite or calcineurin inhibitor immunomodulation.
16 te fungal killing and also provide effective immunomodulation.
17 cellular differentiation, proliferation, and immunomodulation.
18 onse and a PD-L1-dependent allogeneic-driven immunomodulation.
19 tion for the purpose of cancer treatment and immunomodulation.
20 ive approach to upregulate Tregs and achieve immunomodulation.
21 nocytes play an important role in MSC driven immunomodulation.
22 pressor cells primarily implicated in cancer immunomodulation.
23 promising target for small molecule-directed immunomodulation.
24 with the immune system and how they mediate immunomodulation.
25 ific biomarker for type 1 diabetes onset and immunomodulation.
26 further characterising the effects of FOs on immunomodulation.
27 o inform new therapeutic strategies based on immunomodulation.
28 that depletes lymphocytes, causing long-term immunomodulation.
29 regulation and suggest unique strategies for immunomodulation.
30 Polysaccharide and lipid components promote immunomodulation.
31 is via targeted depletion of macrophages and immunomodulation.
32 or the role of glucocorticoids in MW-induced immunomodulation.
33 rammed has led to paradigm-shifting views on immunomodulation.
34 s, and massive lymphocyte apoptosis prevents immunomodulation.
35 use in T cells may reveal novel targets for immunomodulation.
36 as a novel potential target for therapeutic immunomodulation.
37 ted to provide therapeutic immunosuppression/immunomodulation.
38 velopment and, in some parasitic species, in immunomodulation.
39 utinin (FHA) that functions in adherence and immunomodulation.
40 apeutic approach to achieve antigen-specific immunomodulation.
41 ing that A35 increases poxvirus virulence by immunomodulation.
42 metabolic diseases as well as for cancer and immunomodulation.
43 present potential pharmacologic targets for immunomodulation.
44 Cell Death 1 (PD-1) plays a crucial role in immunomodulation.
45 al design will potentially expand to include immunomodulation.
46 constituting a unique target for therapeutic immunomodulation.
47 ue regeneration may, in reality, result from immunomodulation.
48 eceptor modulation in lungs is essential for immunomodulation.
49 t disease (TA-GVHD), and transfusion-induced immunomodulation.
50 in mice, associated with mucosal healing and immunomodulation.
51 bute to eosinophil-mediated inflammation and immunomodulation.
52 f Lck could be a useful adjunct for enhanced immunomodulation.
53 hat the beneficial effect of NECA was due to immunomodulation.
54 as well as efforts to engineer peptides for immunomodulation.
55 he T cell may represent a useful approach to immunomodulation.
56 provide a new strategy for HIV therapies or immunomodulation.
57 ssion of genes important in host defense and immunomodulation.
58 with focused activity that permit selective immunomodulation.
59 TNF-alpha play crucial roles in MSC-mediated immunomodulation.
60 many genes with roles in carcinogenesis and immunomodulation.
61 ing pathogen uptake, antigen processing, and immunomodulation.
62 whereas the CD56bright subset is involved in immunomodulation.
63 ify TGF-beta2 as the crucial mediator of NPC immunomodulation.
64 host organelles, many of which have roles in immunomodulation.
65 e, they are valuable therapeutic targets for immunomodulation.
66 nant proteins to study their contribution to immunomodulation.
67 VEM function during HSV infection: entry and immunomodulation.
68 e function of Treg in the CNS, distinct from immunomodulation.
69 enzyme inhibition, antioxidant, opioid, and immunomodulation.
70 efficacy may be affected by parasite-induced immunomodulation.
71 cytostatics, the molecular mechanisms of its immunomodulation ability have not been investigated thor
77 The pleiotropic effects of statins, such as immunomodulation and anti-inflammatory effects, may also
78 IFN-alpha, an antiviral cytokine involved in immunomodulation and control of HIV type 1 replication,
79 R2 by Bryo-1 has significant implications in immunomodulation and could overcome some of the immune d
80 hMSC) and mouse mesenchymal stem cell (mMSC) immunomodulation and differentiation, depending on the i
81 ns for improved lung remodeling and for dual immunomodulation and direct microbial kill-based treatme
82 me in modulating host health with a focus on immunomodulation and discusses strategies for manipulati
83 yltryptophan conjugates 1 and 2 for combined immunomodulation and DNA cross-link-triggered apoptosis
86 Therapeutic approaches predominantly involve immunomodulation and immunosuppression and are targeted
87 may identify breast cancers more amenable to immunomodulation and indicate additional strategies to e
88 repair through mechanisms that involved both immunomodulation and induction of neurotrophic factors.
89 effect of vitamin D on lung development and immunomodulation and present the evidence of its role in
90 are relevant to depression: synaptogenesis, immunomodulation and regulation of glycogen synthase kin
93 d the molecular mechanisms underpinning such immunomodulation and show here that ES-62-mediated downr
94 and cancer, applied to immune surveillance, immunomodulation and the functions of IgE-mediated immun
96 an primates point to a broader role for PD-1 immunomodulation and to potential applications in humans
98 hese findings identify potential targets for immunomodulation and treatment to combat lethal WNV infe
99 cle regeneration by providing stage-specific immunomodulation and trophic and mechanical support.
100 atients failed to convert with pretransplant immunomodulation and were not transplanted; 51 underwent
102 s, including attachment to epithelial cells, immunomodulation, and competitive exclusion of pathogens
103 bial activity, anticancer, hepatoprotection, immunomodulation, and improving skin health and digestiv
104 e been linked to glioma invasive properties, immunomodulation, and increased angiogenesis, leading to
105 e engineering: multilineage differentiation, immunomodulation, and production of trophic factors.
106 approaches to find a better adjuvant, focus immunomodulation, and reduce allergenicity are under inv
107 on the skin include tanning, carcinogenesis, immunomodulation, and synthesis of vitamin D, among othe
108 -C, whose presentation is resistant to viral immunomodulation, and well-studied HLA-B-restricted epit
110 n, the development of cancer stem cells, and immunomodulation are plausible underlying mechanisms by
112 eir in vivo efficacy and persistence by host immunomodulation are presented in the context of an ever
113 macaques infected without the need for prior immunomodulation as is required for some other models.
114 ediate hemadsorption and be involved in host immunomodulation as well as the induction of protective
115 in gene and drug delivery, diagnostics, and immunomodulation, as well as on the utility of nanoflare
116 4 and RL12/RL13/UL1 loci for virus entry and immunomodulation, but not between genes more distant fro
117 rly childhood and aids in food digestion and immunomodulation, but the mechanisms driving its develop
118 ing to anergy and apoptosis; however, active immunomodulation by accumulating tryptophan catabolites,
121 rphogenesis, with potential implications for immunomodulation by HCMV, and may also be a mechanism by
125 hese data establish a mechanism for systemic immunomodulation by the microbiota and highlight potenti
126 o our understanding of the mechanisms behind immunomodulation by the RRV vIRFs during infection.
127 esis and emergence from latency, elucidating immunomodulation by this medically important cohort of v
128 f the role of carbohydrates in infection and immunomodulation by this significant protozoan parasite.
129 survival of the parasites, helminth-induced immunomodulation can also have a number of benefits for
130 antitumor immune effectors elicited by local immunomodulation can eradicate tumor cells at distant si
131 tiviral and antimicrobial defense, including immunomodulation, cell cycle regulation, cell survival,
133 proteins, which are therefore treatable with immunomodulation, could account for some cases of idiopa
136 rednisolone on microvascular dysfunction and immunomodulation during IRI in rat cardiac allografts su
138 nological adjuvants were incorporated, their immunomodulation effect for cytokine TNF-alpha and IL-6
139 myelitis (EAE) model and observed pronounced immunomodulation evident by a reduction in pro-inflammat
140 es to prevent viral infections, based on the immunomodulation faces many problems related to the ecto
142 he potential usefulness of parasite-mediated immunomodulation for the treatment and prevention of a r
145 d Clinical Immunology Task Force on Diet and Immunomodulation has systematically explored the associa
146 t, gene-directed enzyme prodrug therapy, and immunomodulation have been recently investigated with po
147 studies pointed to a functional link between immunomodulation, histamine production, and folate metab
148 measles infection results in a 2- to 3-year immunomodulation, implicating measles in substantially m
149 hocytes as a novel approach for T lymphocyte immunomodulation in autoimmune diseases without affectin
151 These results reveal a vital role for TNC in immunomodulation in brain tumor biology and demonstrate
153 s of MDSCs and may be a potential target for immunomodulation in conjunction with antiviral therapy d
155 ever, the mechanisms of maraviroc-associated immunomodulation in human immunodeficiency virus (HIV)-i
158 ropathy, and scleritis in patients requiring immunomodulation in patients who have failed or who are
159 kely to be a "one size fits all" approach to immunomodulation in patients with COVID-19. We believe t
162 ttributed with morphological deformities and immunomodulation in susceptible regions of the depressed
163 dies underscore the complex nature of PGE(2) immunomodulation in the context of host-microbial intera
167 ying the therapeutic effects of NSCs include immunomodulation in the periphery and the central nervou
168 ose that not only are microbiota targets for immunomodulation in this disease, but also that microbio
178 at a large amount of work on MGBA focused on immunomodulation, irritable bowel syndrome, and neurodev
185 vertebrate immunity, we also show that host immunomodulation is implicated in the deleterious phenot
186 essional antigen-presenting cells respond to immunomodulation is important for both new innate and ad
187 ny of the studies concluded that BMSC-driven immunomodulation is mediated by the suppression of proin
191 tivate TLR2-signaling and that TLR2-mediated immunomodulation is unlikely to play a significant role
193 ive development of numerous biomaterials for immunomodulation, it is only recently that an experiment
194 re, we identified another mechanism of BILF1 immunomodulation: it targets newly synthesized MHC-I/pep
195 cination argues that neutralization of viral immunomodulation may be a new vaccine paradigm for HCMV
196 nsive evidence suggests that this innovative immunomodulation may be a safe approach to ameliorate al
197 Manipulation of Tregs or other types of immunomodulation may become a part of AML treatment in t
198 echanisms underlying stress effects on fetal immunomodulation may differ based on maternal atopic sta
201 he surgical patient, yet transfusion-related immunomodulation may underlie the association of allogen
202 CD8(+) effector response and reducing local immunomodulation mediated by CD8(+) regulatory T cells.
203 This demonstrates that clinically useful immunomodulation mediated by the S1P(1) receptor can be
204 rol and animal survival were associated with immunomodulation mediated by these 2 agents, which were
205 We therefore tested the hypothesis that immunomodulation might counteract this pathophysiologica
206 n (ILDKT) across HLA/ABO barriers, but added immunomodulation might put patients at increased risk of
207 will require a combination of strategies for immunomodulation, neuroprotection, and myelin replacemen
209 These data indicate that helminth-induced immunomodulation occurs independently of changes in the
210 Grass pollen-specific immunotherapy involves immunomodulation of allergen-specific T(H)2 responses an
211 ation of various cellular pathways including immunomodulation of cancers and regulation of pancreatic
213 fects of IVIG therapy can be mediated by the immunomodulation of DCs, creating a bridge that induces
216 g inflammation during AAA formation and that immunomodulation of IL-17 by MSCs can offer protection a
217 the current study was to explore whether an immunomodulation of infant responses could enhance prote
218 minating bacteria without lysis coupled with immunomodulation of inflammation should be pursued clini
219 model to address the potential mechanisms of immunomodulation of liver disease by creating two unique
220 ies in different tumor models revealed broad immunomodulation of lymphoid and myeloid cells by ADC an
222 iming affinity and have implications for the immunomodulation of pathogenic T cell responses during t
223 on CD4(+) T cells have implications for the immunomodulation of pathologic T cell responses during t
225 support an important role for infection and immunomodulation of T cells in clinical human disease.
227 success as parasites is the result of active immunomodulation of the host immune response, which can
232 f therapeutic vaccination combined with such immunomodulation offers an attractive avenue for the dev
233 , we investigated the effect of prophylactic immunomodulation on the outcome of influenza virus infec
234 crucial component influencing regeneration, immunomodulation or immuno-engineering has emerged as a
235 r disease amelioration is due to nonspecific immunomodulation or mediated by Ag-specific regulation o
236 linked to inflammation, but whether altered immunomodulation plays a causative role in neurodegenera
239 ymptomatic phase of the infection, different immunomodulation profiles were associated with DENV, WNV
240 and mechanistic basis for H. pylori-induced immunomodulation, promoting persistent infection and con
241 unctions, including intercellular signaling, immunomodulation, protein maturation and processing, met
244 Our data indicate that this novel concept of immunomodulation represents a safer method to reduce all
248 emically applied IL-22 did not display acute immunomodulation/stimulation in otherwise untreated or e
251 administration of 6-TG and allopurinol as an immunomodulation strategy in inflammatory disorders.
253 ets serves as a practical means of localized immunomodulation that accomplishes sustained graft survi
254 dentification of potential novel targets for immunomodulation that can be exploited therapeutically.
256 not generally achieved by the same level of immunomodulation that is capable of inducing tolerance o
257 ole for dysfunctional tissue repair in local immunomodulation that may have particular relevance to t
258 onalized, immunophenotype-driven approach to immunomodulation that may include anti-cytokine therapy
260 mRNA and protein and demonstrated a targeted immunomodulation therapeutic effect ex vivo and in vivo,
261 trolled study of a device-based non-specific immunomodulation therapy (IMT) in patients with New York
263 tional thiopurines with or without following immunomodulation (thiopurine-allopurinol, biologicals, m
265 ndicates that for IgE-mediated food allergy, immunomodulation through food immunotherapy is possible;
268 nders this molecule an attractive target for immunomodulation to achieve tolerance to auto- and trans
269 hasone, and support the value of therapeutic immunomodulation to delay the progression to multiple my
270 ntibody responses, suggesting that transient immunomodulation to disrupt B/T-cell interaction at the
273 d should provide targets for neuroprotective immunomodulation to treat these devastating neurodegener
275 u ammonis 1-3, and dentate gyrus) targets of immunomodulation-treated LGI1 VGKC-complex antibody-medi
276 nfluenza A/PR/8/34 virus 24 h after the last immunomodulation treatment and either monitored for surv
278 ugh the appropriate targets for intratumoral immunomodulation using this strategy are not known.
279 tivation of interleukin 1beta (IL-1beta) and immunomodulation via MyD88, the first signaling molecule
280 ed this agent could provide a novel route of immunomodulation via targeted inhibition of antigen-indu
282 e contribution of the purinergic mediator to immunomodulation was confirmed by exposing in vitro diff
284 interferon (IFN-gamma) production suggested immunomodulation, which was not restricted to parasite-s
288 These findings highlight that intratumoral immunomodulation with an oncolytic virus expressing a ra
289 some residual lesions after steroid use and immunomodulation with associated clinical recovery in pa
290 tion for MS, because it combines features of immunomodulation with beneficial effects on neuroregener
296 ating tumor progression through intratumoral immunomodulation, with broad implications in developing
299 ing mechanisms in therapeutic resistance and immunomodulation within the tumor microenvironment.