ライフサイエンスコーパス: impetus

1 y, and they have given these disciplines new impetus.

2 This provides powerful impetus and a growing demand for researchers to develop

3 These results provide impetus and further guidance for the development of thes

4 ly mammalian embryogenesis, which provide an impetus and opportunities for future investigations.

5 We hope that this review article offers the impetus and roadmap for the development of next-generati

6 nd-targeted nanoparticles have been the main impetus behind the progress of nanomedicines towards the

7 The impetus behind these reports comes from different source

8 ally one stem cell type that, with the right impetus, can create whatever progeny our heart, liver or

9 tion number of a trigonal-planar geometry is impetus enough to make even the electronegative cobalt w

10 The synthesis attempted here provides an impetus for a conceptual shift that links cognitive and

11 ions addressed by this research provided the impetus for a decades-long effort-still in full force to

12 ar follow-up in isolated MR and provides the impetus for a large-scale clinical trial with clinical o

13 a subgroup of tinnitus patients and provides impetus for a larger pivotal study.

14 arative organismic biology have provided the impetus for a major re-evaluation of the earliest phases

15 The main impetus for a mini-symposium on corticothalamic interrel

16 ctive immunity in animal models, fueling the impetus for a vaccine.

17 gh alternative novel mechanisms and provides impetus for additional investigation.

18 This study provides further impetus for additional research into the influence of mo

19 vous and/or skeletal systems and provide the impetus for additional studies aimed at identifying the

20 nnel 6 (TRPC6) protein, which is the genetic impetus for an autosomal dominant form of FSGS.

21 conducted at Memorial Hospital served as the impetus for an intergroup adjuvant E1694/S9512/C509801 t

22 This observation provides impetus for analysis of other complex networks of side-c

23 anisms of normal physiology but also provide impetus for application of these findings to studies of

24 on of the RNase A superfamily, as well as an impetus for applying this methodology to other ribonucle

25 have stirred controversy and have become the impetus for calls to abandon recommendations for reduced

26 m those in water and can provide some of the impetus for catalytic processes.

27 ence, with random fluctuations as sufficient impetus for cell reorganization.

28 Adding to the impetus for change are the attendant realities of the jo

29 without high costs is required to provide an impetus for change.

30 ed rhythmicity, in addition to providing the impetus for circadian oscillations in general.

31 cetylcysteine in this mouse model provide an impetus for clinical evaluation of glutathione repletion

32 ngaged by IL-18/IL-2 and provide preclinical impetus for clinical investigation of this potent anti-t

33 These findings provide an impetus for continued studies into the complex role of C

34 cells and vesicles have provided additional impetus for decreasing the probe dimensions.

35 ern through clinical observations, providing impetus for deeper investigation of the disease subtypes

36 ssure-distance paradox and predicts that the impetus for defect plane insertion is tunable via variat

37 reased demand for services have provided the impetus for delivering team-based primary care.

38 ase progression and involvement has provided impetus for design of new enzyme therapies, and creation

39 l, no vaccine, and insufficient access to or impetus for developing affordable new drugs.

40 r RNA-mediated crosstalk in PH, providing an impetus for developing blood-based miR-210 technologies

41 dies have been published, providing a strong impetus for developing databases to warehouse experiment

42 of the current process provide an essential impetus for developing newer separation protocols, most

43 is, characterising NCBT in melanoma provides impetus for developing novel therapeutic targets for mel

44 These data will hopefully provide the impetus for development of novel compounds that use mult

45 acy of AR antagonists, thus establishing the impetus for development of RD-based mimetics.

46 n of L-nucleoside analogs, providing further impetus for discovery and clinical development of new ag

47 nic effects in diabetic patients and provide impetus for efforts to develop PPARgamma ligands that se

48 Our study provides an impetus for elucidating the molecular determinants that

49 are unclear, this may provide an increasing impetus for emigration of recruits to other colonies in

50 generally, this emit-receive concept is the impetus for enabling new signal processing schemes.

51 Our data reduce the impetus for equating Sho with the notional pi protein an

52 The pursuit of happiness and reward is an impetus for everyday human behavior and the basis of wel

53 The impetus for examining microbial communities in different

54 These observations provide strong impetus for expanding genomic and molecular studies on c

55 erse array of pathologies, and provide a new impetus for exploiting this fascinating recognition syst

56 modulate soluble and bound signals provides impetus for exploring mechanobiology paradigms in regene

57 cal models on the origin of species, and new impetus for exploring putative plant and animal examples

58 Moreover, our results provide further impetus for exploring the helix alphaC patches of other

59 This was our impetus for forming the "Pedigree-Based Whole Genome Seq

60 The impetus for framing this question lies in the current in

61 during eukaryotic evolution, and provide the impetus for further detailed studies of the possible evo

62 This study provides impetus for further development of a safe, highly effect

63 me in burned humans, and our results provide impetus for further investigation of the role of the inf

64 Our findings provide impetus for further investigation of this compound as a

65 amination; however, they do provide a strong impetus for further monitoring and analysis of groundwat

66 rtance of TRPA1 in cold exposure and provide impetus for further research into developing therapeutic

67 anticipated that these data will provide an impetus for further studies to determine injury severity

68 This data provides impetus for further studies to determine its viability a

69 inistration of a rAAV vector and provide the impetus for further studies to exploit its use as a tool

70 ble therapeutic resistance, has provided the impetus for further study into how Mcl-1 is involved in

71 new role for Htt in translation and provide impetus for further study into the link between protein

72 onged progression-free survival) provides an impetus for further study of HDM2 inhibitors in liposarc

73 nd its oxidation products for U(VI) provides impetus for further study of mackinawite as a potential

74 utologous nature of this biomaterial provide impetus for further translation.

75 These findings may provide an impetus for future investigations of supplemental nucleo

76 These findings provide impetus for future investigations on nanoparticle-mediat

77 l roles in vivo and provides a framework and impetus for future larger-scale functional investigation

78 The results of this study provide impetus for future positional cloning of QTLs regulating

79 These results provide impetus for future positional cloning of quantitative tr

80 ther gammaherpesviruses and thus provides an impetus for future studies analyzing the role of the gam

81 be considered "hypothesis generating" and an impetus for future studies regarding the effects of foli

82 This study provides impetus for future work in motion perception and its rel

83 Our results provide an impetus for gaining a deeper understanding of ANO1 modul

84 The law also provides impetus for greater collaboration between the US health-

85 These stochastic events can provide the impetus for heritable phenotypic change in bistable epig

86 dent of the major death pathways and provide impetus for identification of novel death pathways preci

87 ally overexpressed has provided an important impetus for identifying activators of utrophin expressio

88 atotic livers undergoing surgery is a strong impetus for identifying the mechanisms responsible for h

89 e these concerns about image, surgeons found impetus for improvement because of poor outcome scores o

90 by SIV infection in the CNS may provide the impetus for increased transcription of MAO B and that MA

91 in non-mammalian cynodonts may have provided impetus for increasing vertebral complexity in mammals.

92 This provided an impetus for intense research into the mechanisms of modu

93 t these results will provide methodology and impetus for investigating iso-CoA compounds as potential

94 Our results may trigger a renewed impetus for investigating structural differences in the

95 acial foragers, perhaps providing an initial impetus for investment in ceramic container technology,

96 of 99mTc-sestamibi tumor uptake provided the impetus for its evaluation as an adjunctive technique.

97 and how seminal research studies provide an impetus for its public health policy and programs.

98 Our findings provide impetus for larger trials to assess the effects of vitam

99 lar "metabolic flux" was proposed as a novel impetus for metabolic regulation.

100 zed using a biomimetic process, and that the impetus for mineral nucleation in this system appears mo

101 Rather than serving as an impetus for mitochondrial ATP generation, matrix NADH ra

102 t this critical assessment will increase the impetus for more carefully considered and rigorous desig

103 of biodiversity loss and should serve as an impetus for new biodiversity experiments.

104 tial aspects of chronic pain and provides an impetus for nonpharmacological cognitive and physical th

105 been disappointing, therefore providing the impetus for novel combination drug trials.

106 hanism inherent to pathogens and provide the impetus for preparing second generation analogues as a p

107 The impetus for rapid results is the availability of effecti

108 Finally, MSC/CD34(+) grafts provided the impetus for rapid urothelium regeneration.

109 evious conflicting results and constitute an impetus for reanalyzing previous data sets, taking into

110 tion and lineage commitment and provides new impetus for reexamining lineage models.

111 nships for numerous operations, providing an impetus for regionalization; however, volume-based regio

112 covery of P. ramorum in Asia provide renewed impetus for research on the sudden oak death pathogen.

113 bal insect diversity and provides additional impetus for research on tropical diversity.

114 al carbon nanotubes (CNTs) have provided the impetus for researchers in developing high-performance c

115 with hypersexuality provides a motivational impetus for seeking this reward behaviour through activa

116 However, its phenotypic consequences and impetus for selection are not well understood.

117 e implications of this study may serve as an impetus for similar improvement efforts.

118 The impetus for strategic rescheduling of operations is mult

119 This has led to an impetus for the chemical synthesis of oligosaccharide fr

120 e-molecule biophysics has provided a renewed impetus for the construction of quantitative models of b

121 isease is an ongoing threat and serves as an impetus for the continued development of novel approache

122 the E2F transcription factors provide growth impetus for the continuous proliferation of melanoma cel

123 pted daily requirements has provided a major impetus for the critical examination of dietary approach

124 Finally, these observations provide the impetus for the design of a new family of inhibitors of

125 ne-nucleation mechanism and could also offer impetus for the design of new 3D spatial structures of g

126 s of surgical interventions has provided the impetus for the development of a catheter-based approach

127 morbidity and mortality, providing an urgent impetus for the development of a vaccine that is effecti

128 ic myelogenous leukemia, has created a great impetus for the development of additional kinase inhibit

129 These data provide the impetus for the development of an attenuated HTLV-2-base

130 lication in vivo These data serve as further impetus for the development of an immunocompetent mouse

131 These data serve as further impetus for the development of an immunocompetent mouse

132 The findings may provide an impetus for the development of DPP-4 inhibitors for the

133 key in the OP mechanism, thus giving further impetus for the development of malaria vaccines targetin

134 e-threatening side effects and have provided impetus for the development of more selective anti-clott

135 he anti-CSC properties of 1 provide a strong impetus for the development of new metal-based compounds

136 These findings provide impetus for the development of new therapeutic agents.

137 disrupting the association with Hdm2 was the impetus for the development of Nutlin3.

138 atial and temporal resolution, providing the impetus for the development of synchrotron facilities us

139 d with several cancers, our findings provide impetus for the development of targeted educational inte

140 t for tuberculosis treatment has provided an impetus for the discovery of adjunctive host-directed th

141 An important early impetus for the establishment of this reserve system was

142 ting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic el

143 oproteins, such as HA, may have been a major impetus for the evolutionary establishment of this recyc

144 These data provide further impetus for the ex vivo use of anti-CD40L mAb to block G

145 Polynesian motif, perhaps also providing the impetus for the expansion into Polynesia.

146 The presented data serve as impetus for the further development of the ec-LLS proces

147 These results provide new impetus for the generation of selective Mcl-1 inhibitors

148 y toxicity testing of chemicals provides the impetus for the incorporation of novel methodologies int

149 , the Toll receptors of the fly provided the impetus for the investigation of Toll-like receptors, wh

150 uality improvement initiatives and potential impetus for the regionalization of important NICU resour

151 in hypertensive populations, and provided an impetus for the search for cortisol-sparing CYP11B2 inhi

152 These findings should provide further impetus for the search for measures to prevent or delay

153 atment of complex abdominal EVAR and provide impetus for the standardization of these techniques in t

154 ately 37% at the basal layer) is the driving impetus for the start of cell migration after injury whe

155 Impetus for the study derives from the need to perform d

156 ratory virus infection, and they provide the impetus for the study of this treatment regimen in RSV-i

157 Cav-1 via autophagy, which provides further impetus for the use of antioxidants in anticancer therap

158 use visual cortex and should provide further impetus for the use of mice in studies on the genetic an

159 Much of the impetus for the use of radiofrequency ablation has come

160 The main impetus for these changes, which are more intensive than

161 from trans-acting factors-have provided the impetus for these discoveries.

162 The impetus for this approach was that SR FT-IR microspectro

163 This is a primary impetus for this article in which we describe the typica

164 The impetus for this change comes from the deep impacts that

165 These latter findings serve as an impetus for this current review to assess the optimal se

166 The impetus for this move stems from several considerations,

167 The impetus for this recommendation is based on recent appre

168 The conference provided the impetus for this Review, which describes, in historical

169 The impetus for this study was our desire to evaluate the po

170 The impetus for this work is to help resolve large discrepan

171 This may provide some impetus for those sedentary to become more active.

172 ercialization of cognitive neuroscience, the impetus for training in ethics, and the increased attent

173 , issue of Genes & Development, provides the impetus for uncovering the mechanistic and functional pr

174 After the impetus for understanding the influence of social and cu

175 forbiddenness" of concerted reactions and an impetus for untold numbers of research projects.

176 /off combinations, thereby providing further impetus for use of the 2C7 epitope in a gonococcal vacci

177 tween normal and necrotic myocardium was the impetus for widespread clinical use for demonstrating th

178 ly tunable ligand system may provide further impetus for work in this important area of catalysis.

179 Our results help to build the impetus for, and confidence in, including microbial mech

180 Nevertheless, there has been an impetus from experts in the field to modify these defini

181 to optimize health benefits and will provide impetus from health systems for the preservation of ecos

182 (hRSV) vaccine development has received new impetus from structure-based studies of its main protect

183 tem structure and function have received new impetus from the federal Brain Research through Advancin

184 f these enzymes in bacteria, probably due to impetus from the primary oxygenation event in Earth's hi

185 ration across multiple organizations for its impetus in improving research quality, advancing efficie

186 ognitive theories have received considerable impetus in regard to both human and animal learning from

187 The current impetus in research concerns establishing the underlying

188 Nanomedicines have provided fresh impetus in the fight against cancer due to their selecti

189 Impetus includes indications that EPO affects significan

190 This impetus is largely a result of the 2005 Institute of Med

191 At the turn of the 20th century under the impetus of anesthesia, such surgical stalwarts as Mayo R

192 ems in a simpler formalism is the underlying impetus of biological sciences.

193 Spindle defects are not only an impetus of chromosome instability but are also a cause o

194 The impetus of earlier newborn discharge places increased em

195 Under the impetus of the Human Genome Project, new disease-associa

196 The impetus of these efforts is to learn from the microbes t

197 oblem of long-standing interest, with recent impetus provided by the relevance of these issues to the

198 There has been an impetus to accelerate MC simulation on GPUs whereas thre

199 The LC might provide the impetus to act when the predicted outcome value is low.

200 an (18)F-FDG-based approach, it provides an impetus to better characterize the determinants of (18)F

201 The recent surge in obesity has provided an impetus to better understand the mechanisms of adipogene

202 For still others, this may provide some impetus to better understand the origins of modern imagi

203 Tax incentives can provide a large financial impetus to change behavior.

204 This will hopefully provide the necessary impetus to change the culture of the training environmen

205 ary pharmacokinetic (PK) profile provided an impetus to change the pharmacophore from a bisaryl urea

206 ary pharmacokinetic (PK) profile provided an impetus to change the pharmacophore from a bisaryl urea

207 e immunostimulatory effects has provided the impetus to combine chemotherapy and immunotherapy for sy

208 ing reversible contraception provides strong impetus to define immunomodulatory properties of this ex

209 multiple genetic causes will provide further impetus to describe the pathway leading to PD.

210 inity of compounds 2d-g to PKCs gives us the impetus to design additional molecules that would retain

211 rmative developmental processes provides the impetus to design and implement randomized control trial

212 This mechanism provides the impetus to design DNA damaging agents that produce DSBs

213 t mammary cancer in an animal model provides impetus to determine its activity in a clinical setting.

214 ynaptic plasticity in the brain, and provide impetus to develop 3'-O-Me-EC-Gluc and other brain-targe

215 as active electronic components provided the impetus to develop a variety of experimental platforms t

216 There remains a continued impetus to develop and amass experience with new therape

217 The current lack of treatment for DEB is an impetus to develop gene therapy strategies that efficien

218 The lack of therapy for DEB provides an impetus to develop gene therapy strategies.

219 heir functions elucidated, providing a major impetus to develop gene-based treatments.

220 ur original hypothesis and providing further impetus to develop Gpr17 antagonists for the treatment o

221 e resistant to this treatment, providing the impetus to develop molecules that sensitize cells to ion

222 These data provide the impetus to develop new therapeutic interventions for tel

223 remediation has inspired a recent scientific impetus to develop oil-absorbing smart nanomaterials.

224 This study also provides an impetus to develop personalized immunotherapy targeting

225 naging in-stent restenosis have provided the impetus to develop provisional stenting strategies.

226 These observations provide an impetus to develop strategies directed toward generating

227 This study provides impetus to develop therapies that abrogate AR-V7 signali

228 hortage of transplantable organs provides an impetus to develop tissue-engineered alternatives.

229 acteria in recent years have provided strong impetus to discover new antibiotics and alternative trea

230 -held psychosine hypothesis, and provide the impetus to discover safe and effective inhibitors of ACD

231 ocation and their untapped potential provide impetus to discover strategies to turn them against tumo

232 e tumour and its microenvironment have given impetus to drug discovery and patient evaluation of inte

233 gs that evolved from them, that provided the impetus to establish in 1955 the national drug developme

234 ed cirrhosis mortality, and provides further impetus to evaluate coffee as a potential therapeutic ag

235 being used for clinical diagnostics, with an impetus to expand reporting of incidental findings acros

236 This work should provide an impetus to experimentalists for designing better electro

237 ithium and cobalt, the increasing cost gives impetus to exploit low-cost rechargeable battery systems

238 These findings may provide impetus to exploit the role of Ad-36 proteins as novel t

239 ber of factors have coalesced to provide the impetus to explore alternative renewable sources of carb

240 other microtubule stabilizers, provides the impetus to explore the therapeutic potential of this sit

241 Our findings provide an impetus to further explore Aspm's role in facilitating W

242 es to the inner core saccharides provides an impetus to further explore this compound as a vaccine ca

243 is hoped that these results will provide an impetus to further research and act as a useful benchmar

244 concerns understood to provide the necessary impetus to go to the clinic.

245 e in humans and nonhuman primates have given impetus to identification of host tropisms and potential

246 diverse roles attributed to DC-SIGN provide impetus to identify ligands that can be used to explore

247 This has provided impetus to identify other co-inhibitory receptors that c

248 tes in experimental animal models, providing impetus to identify pharmacological approaches to modula

249 t of expression profiling has provided a new impetus to identifying clinically useful prognostic mark

250 For this reason, there is impetus to implant children at a very young age, as a co

251 ropriate funding will be required to provide impetus to implement these recommendations.

252 nterest in exploring the deep ocean provides impetus to increase our understanding of the deep-sea pi

253 ication rate, not temperature per se, as the impetus to increase the expression of the OspC and Erp i

254 early single-center trials that provided the impetus to initiate phase 3 trials.

255 These data provide impetus to investigate how baseline COX-2 expression is

256 ation of mTOR activity, therefore, providing impetus to investigate if a leucine-sensing mechanism in

257 Our work provides further impetus to investigate this relationship in tandem with

258 Our study provides the impetus to investigate whether manipulation of splicing

259 e responses of self-reactive T cells, giving impetus to manipulation of this pathway for treating hum

260 regulate a myriad of target genes, providing impetus to many laboratories to identify these genes.

261 modulating radiosensitivity and provides the impetus to monitor the influence of Prx1 levels in the m

262 re sepsis patients (PROWESS trial) that gave impetus to new directions for basic and preclinical rese

263 , in the last few decades gave a significant impetus to powerful functionalization of indoles at virt

264 two zinc fingers of NCp7, thus providing an impetus to pursue development of highly selective zinc f

265 nematode Caenorhabditis elegans provided the impetus to re-examine the end structure of mammalian tel

266 They also provide an impetus to reevaluate prior studies in which GluR and GL

267 new studies in the past 2 years serve as an impetus to reframe the debate into a reasonable discussi

268 These data provide new impetus to resolve how store Ca(2+) content is sensed an

269 tation of baseline probabilities and has the impetus to restore them.

270 inomic" structure-function space provides an impetus to screen venom from other Conus species for sim

271 ignals involved, will soon provide a further impetus to stem cell biology with far reaching applicati

272 cycle functions of cyclin D1 and provide the impetus to study its pleiotropic effects in androgen-dep

273 ring telomerase activity thus provides ample impetus to study the biogenesis and regulation of this e

274 erged as problematic pathogens, providing an impetus to study the potential of PNAG to be targeted fo

275 Their findings provide further impetus to study these molecules and associated signalin

276 lts for the specified wavelength serve as an impetus to suggest the need for two independent measurem

277 advances in stem cell biology have given new impetus to the "cancer stem cell hypothesis." Two import

278 ance with documented absence of CAN may give impetus to the clinical application of tolerance.

279 ding to the dominant helper epitopes, giving impetus to the development of a similar approach in the

280 in ALK translocation-driven cancers, lending impetus to the development of novel anaplastic lymphoma

281 shed or pulled from the animal, and provides impetus to the development of pultrusion-based biomimeti

282 These findings provide impetus to the development of structurally diverse, next

283 f sentinel-lymph-node biopsy has brought new impetus to the early staging of cancer in general, and b

284 This has provided the impetus to the establishment of large-scale mutagenesis

285 These results lend impetus to the further development and broader implement

286 antibodies (bNAbs) has provided an enormous impetus to the HIV vaccine research and to entire immuno

287 it or promote their activity has lent a huge impetus to the immunotherapy of melanoma.

288 s, and patient preferences provided addition impetus to the popularity of ambulatory surgery.

289 We anticipate this method to give great impetus to the practical improvement of ion-beam cancer

290 e traits" in chronic airways disease, adding impetus to their evaluation and management in difficult

291 Genome and HapMap projects have added fresh impetus to this goal by cataloguing the raw genetic data

292 Thus, there is a major impetus to understand the regulation of AR action.

293 This adds further impetus to understanding compartmentalization of functio

294 plete sequencing experiment and provides the impetus to use ddPCR-based quantification for improvemen

295 lower enantioselectivity, which provided the impetus to use structure enantioselectivity correlations

296 lity of those agents has provided the strong impetus to utilize this novel class of materials to engi

297 lescent mental healthcare are giving renewed impetus to work in primary care.

298 Recently, new impetus, tools, and model systems have emerged to re-exa

299 This development has provided renewed impetus toward an HIV vaccine and led directly to the de

300 ivery for repair and regeneration is gaining impetus with our understanding of constructing tissue-li