ライフサイエンスコーパス: impose

1 ng but also on the pace at which changes are imposed.

2 sable when full transcriptional silencing is imposed.

3 temperature; a late-summer drought was also imposed.

4 cating that sexual identity is not uniformly imposed.

5 opoiesis, serving either to facilitate or to impose a barrier to V(D)J recombination.

6 hip is globally representative, humics could impose a concentration threshold that buffers the deep o

7 Enteric fever can impose a considerable economic burden in Pakistan.

8 Enteric fever can impose a considerable economic burden on patients, careg

9 Infections caused by parasitic flatworms impose a considerable worldwide health burden.

10 Infections with enteric pathogens impose a heavy disease burden, especially among young ch

11 istent with data that lymphocyte TL dynamics impose a limit on T-cell proliferation.

12 It is popularly speculated that this might impose a mental-health burden on women and their childre

13 her end of opposing signaling gradients, and impose a pattern of proliferation that matches derivativ

14 nse, severely affected countries have had to impose a range of public health strategies achieved via

15 ions, we show that large Trinidadian guppies impose a significantly larger competitive pressure on co

16 that heat, pH, and growth arrest effectively impose a similar type of proteostatic stress at the cell

17 Orofacial clefts and their management impose a substantial burden on patients, on their famili

18 Consequently, metabolic factors impose a very tight control over kisspeptin synthesis an

19 The system imposed a consistent post-anthesis HNT stress of + 3.8 d

20 itudinally (streamwise) oriented vortex that imposed a continuous roll perturbation, measured wing ki

21 d so after an experimental manipulation that imposed a feeding delay (Experiment 2), which increased

22 hermal updrafts at the start of the day also imposed a metabolic cost, with birds flapping toward the

23 We have demonstrated that RSV imposed a substantial economic burden on health systems,

24 enhanced the generation of T(reg) cells and imposed a transcriptional profile similar to that induce

25 that Re enriches to partial dislocations and imposes a drag effect on dislocation movement, thus redu

26 that the P450-mediated metabolic resistance imposes a high fitness cost in malaria vectors supportin

27 the Heisenberg uncertainty principle, which imposes a limit to the precision with which the position

28 The sparsity of the fossil record, however, imposes a limit to the strength of inference that can be

29 Primary and acquired drug resistance imposes a major threat to achieving optimized clinical o

30 using different software applications, which imposes a practical limitation and potentially a negativ

31 ity of life of women and their partners, and imposes a profound personal and societal economic burden

32 is a presumed tumor suppressor pathway that imposes a proliferative barrier (the Hayflick limit) dur

33 This imposes a severe challenge to cytosolic proteostasis and

34 Atopic dermatitis imposes a significant burden on patients, families and h

35 It imposes a significant burden, with annual costs of up to

36 r containment that can eradicate the disease imposes a smaller loss than shorter ones.

37 ng that asymmetric repair of nucleosomal DNA imposes a strand polarity on UV mutagenesis.

38 Water availability imposes a strong selection leading to differentiation of

39 ing the peptide-MHCII (pMHCII) repertoire by imposing a bias on the foreign and self-derived peptide

40 of succinate-mediated HIF-1alpha activation, imposing a consequent reduction of LPS-induced Il1b expr

41 ons utilize two or more exogenous promoters, imposing a currently unquantifiable metabolic burden on

42 m microenvironments of extracranial lesions, imposing a distinct and profound selective pressure on t

43 ly limiting rates, by up to 25%, effectively imposing a fourth limitation on A.

44 Increased perceptual load in a task (imposing a greater demand on neural computations) should

45 ial to volant-challenged early pterosaurs by imposing a high energetic burden, thus requiring flight

46 ses the risk of non-communicable disease, by imposing a high metabolic load on a depleted capacity fo

47 simulation for disease propagation in graphs imposing a local structure to allowed disease transmissi

48 ut its function was modulated by INSIG, thus imposing a second layer of control on Hmg2 regulation.

49 pends on the solubility of the chosen salts, imposing a stringent restriction on the number of possib

50 w optimal mitigation pathways evolve without imposing a warming limit, finding that median abatement

51 on restores sodium and chloride excretion it imposes added physical stress on the filtration barrier

52 isting methods, the proposed method does not impose additional locality constraints on the spectral f

53 e reactions in upper layers of the hierarchy impose an upper bound on the flux of the reactions downs

54 ynamics, and the high speeds required likely impose an upper limit to the body size and effectiveness

55 The lateral contraction of alpha' imposed an interphase tensile microstress in the transve

56 Peanut allergy imposes an adverse psychosocial impact on patients and c

57 etic ablation of POLR1A-high cell population imposes an irreversible growth arrest on CRCs.

58 use of geometric constraints that the cavity imposes and an unfavourable Purcell effect that can modi

59 mentation with Lactobacillus reuteri did not impose any phenotypic changes of the conventional T cell

60 diverse regulatory strategies integrated to impose appropriately patterned gene expression that unde

61 evel; acute hypoxia ( PET,O2 = 50 mm Hg) was imposed at baseline and at each thermal extreme.

62 thresholds within the range of deluge sizes imposed, at least during this dry year.

63 stages of their development and how the TME imposes barriers to the metabolism and activity of tumor

64 RTN is measured due to changes in externally imposed basal pH.

65 hat the compost system can be manipulated to impose biotic and abiotic stresses for testing how micro

66 it may enhance immediate survival, this self-imposed bodily damage may convey long-term consequences.

67 more, to enforce biological plausibility, we impose both spatial and temporal structure so that the t

68 o biological differences, or to a distortion imposed by a detection threshold limit.

69 This configuration is imposed by a distinct conformation of the PlexinC1 extra

70 inherently proportional to limb velocity and imposed by a synchronization of breaths to strides is st

71 vercome the translation termination blockage imposed by an arrest peptide.

72 with a focus on their functional specificity imposed by cell-type-dependent expression, subcellular l

73 dysbiosis or selection (on host or bacteria) imposed by chronic radiation exposure.

74 iations of the actual director from the axis imposed by confinement.

75 Finally, the limitations imposed by contrasting succulent systems and associated

76 ogether with strong deterministic constrains imposed by diet and age, stochastic colonization in earl

77 The thermodynamic penalty imposed by differences in isomerization for the ATP and

78 study, we compare the geometrical signatures imposed by different possible mechanisms for the packagi

79 that evade the cell cycle blockage normally imposed by DNA damage experience sustained p53 signaling

80 of the markedly different fitness landscape imposed by domestication.

81 of EC1 alone but shows that steric hindrance imposed by EC2 would likely prevent multiprotein binding

82 termine whether its obligate anaerobiosis is imposed by endogenous reactive oxygen species or by mole

83 we show that the lateral confinement, often imposed by experimental setups or in harbors and locks,

84 The selective pressure imposed by extrinsic death signals and stressors adds to

85 erved under flow is a genuine physical limit imposed by flow-mediated washout of active coagulation f

86 Here we show that the limitations imposed by fluid instabilities with thermally drawn nano

87 Removing the constraints imposed by having to maintain cell viability might facil

88 Tortuosity imposed by hemoglobin was verified by demonstrating rest

89 ate enables HIV to evade selective pressures imposed by host immune responses.

90 tic processes, such as the selective filters imposed by host traits [6-8].

91 ing how each trait evolves through selection imposed by interacting partners.

92 t per square metre, owing to the limitations imposed by interfacial effects-as seen in characterizati

93 Our data suggest that a balance of forces imposed by intermediate filaments and microtubules is re

94 nsduction beyond the conventional limitation imposed by intrinsic symmetry.

95 z photon(14), reaching the fundamental limit imposed by intrinsic thermal fluctuations at 0.19 kelvin

96 are mechanically robust to the bodily damage imposed by leg loss.

97 i plays a critical role in modulating stress imposed by limitation of these two critical nutrients in

98 ocks appears to be prohibited by constraints imposed by liquidus phase-equilibria on evolution of man

99 with selection pressure on the viral genome imposed by local and systemic movement.

100 hile proper understanding of the assumptions imposed by model parameters can help avoid overinterpret

101 ors, with one neuron type mediating aversion imposed by multiple poisons.

102 to speed, specifying the fundamental limits imposed by natural stimuli.

103 approach the theoretical limits for accuracy imposed by natural variability in these metrics within o

104 other cells while enduring the shear stress imposed by navigating small vessels and sinusoids.

105 Cognitive rigidity imposed by neural circuit adaptations during nicotine ab

106 terpreted as the result of intense selection imposed by newts.

107 whether synapses also adjust to life stages imposed by novel developmental programs for which they w

108 The reduction of energetic demands imposed by overload relief allowed the mitochondria to r

109 Selective pressures imposed by pathogens have varied among human populations

110 The inflammatory burden imposed by periodontitis can increase serum hsCRP levels

111 In particular, selection imposed by plant habitats strongly shapes the diversity

112 icient to overcome the metabolic constraints imposed by plasmablasts and enhanced parasite clearance

113 ed because of spatial variation in selection imposed by predation.

114 ng performance, and quantify the limitations imposed by realistic diffusion and reaction rates.

115 lly found solutions to the oxidative threats imposed by ROS by evolving an elaborate detoxification s

116 een developed that overcomes the limitations imposed by shallow penetration depth of ultraviolet exci

117 ethods for predicting the fundamental limits imposed by stimulus variability on sensory-perceptual pr

118 rising from thermal fluctuations, the limits imposed by structural heterogeneity have remained unclea

119 was impaired by the accumulative heat stress imposed by the 3HW treatment.

120 ratio because of the alignment of these dyes imposed by the crystallographic structure.

121 conversely this induced a greater limitation imposed by the cytosol on CO(2) transport, further reduc

122 or prosthesis design by lifting restrictions imposed by the embodiment theory for artificial limbs.

123 The folding mechanism is likely imposed by the final structure and might have evolved to

124 ation and mitigation strategy (REMS) program imposed by the Food and Drug Administration for mifepris

125 The spherical curvature imposed by the graphitic mesopores enables the generatio

126 s under the demanding experimental condition imposed by the high-power laser interaction.

127 election, the balance of drift and selection imposed by the HSPC population size, and the mutation-se

128 actions combined with stereochemical effects imposed by the locally strained structural context.

129 -based assays that overcome the restrictions imposed by the NE environment.

130 In order to circumvent limitations imposed by the normally harsh reaction conditions, chemi

131 a major element in the permeability barrier imposed by the outer membrane and offers a pathogen-asso

132 viates from its ideal cuboctahedral geometry imposed by the perovskite cage and behaves as a heavy at

133 However, the constraints imposed by the prior distributions in CoGAPS limit the a

134 uctural adjustments of the DNA substrate are imposed by the protein; however, how APE1 uniquely sculp

135 However, the bottleneck imposed by the requirement for isolates precluded genomi

136 ity within the bone marrow microenvironment, imposed by the stages of bone turnover.

137 However, metabolic constraints imposed by the tumor microenvironment (TME) can dampen t

138 ased understanding of the treatment barriers imposed by the tumour-associated stroma, and from the de

139 , in part, differing functional requirements imposed by the use of varied tool-kits.

140 We then review the analytical challenges imposed by the volume of data and discuss methods to rec

141 y of online learning with the practicalities imposed by this crisis and any future crises.

142 The reduction in conformational diversity imposed by this design also enhances the nascent peroxid

143 Lifting the constraints imposed by this principle could circumvent deleterious e

144 suggesting that the assembly specificity is imposed by trans-acting factors in vivo.

145 on and extinction depends on the constraints imposed by trophic, service, and engineering dependencie

146 These deviations reflect constraints imposed by tumor fitness selection pressures.

147 changing sensory capacities, including those imposed by various laboratory conditions.

148 hen exposing cells to the higher strain rate imposed by xDC, cellular components other than the actin

149 positive selection, while medullary (m) TECs impose central tolerance on the T cell repertoire.

150 Spaceflight is known to impose changes on human physiology with unknown molecula

151 colectomy, the features of liver imaging can impose characteristics that could be predictive for meta

152 These properties can be exploited to impose circadian expression, which is asymmetric and var

153 increasing number of cells and batch effect impose computational challenges.

154 nce of neglect of national health systems or imposed conditionalities under neoliberal governance wer

155 his approach requires multiscale procedures, imposing considerable challenges to many labs.

156 This arrangement imposes constraints on how the information can be tailor

157 mation than has been appreciated previously, imposing constraints on regulatory evolution.

158 actions with other seed predators, which may impose contradictory selective pressures.

159 iotropy may result from genetic changes that impose correlations between otherwise independent traits

160 different SES in the context of temporarily imposed COVID-19-related social restrictions present a u

161 ions to population structure can exogenously impose Darwinian-like properties on communities.

162 i, interior positive), and the effect of the imposed DeltaPsi on the kinetics of efflux was also stud

163 a pK(app) of ~7.2 that is unaffected by the imposed DeltaPsi; 2) DeltaPsi increases the rate of effl

164 cal properties and induces mobile charges to impose directional fluid flow.

165 Interestingly, swi1Delta and [SWI(+)] impose distinct and oftentimes opposite effects on cellu

166 However, mutant receptors imposed distinct conformations in beta-arrestin2 and dif

167 at play in normal and cancer conditions, but imposing distinct developmental constraints.

168 onary cycles as specialization in herbivores imposes diversifying selection on plant chemical defense

169 We imposed drought and competition treatments on diverse ge

170 ty environments and the physical constraints imposed during crystal growth.

171 these two functional pools, especially when imposed during the crucial seed setting stage is unclear

172 d between them due to functional constraints imposed during the early evolution of each group.

173 onality of the synthetic water channels also imposes engineering difficulties to align them in membra

174 se, and these studies have used experimenter-imposed extinction or forced abstinence procedures.

175 The under-specification of random effects imposes far stronger constraints on the generalizability

176 In less despotic species, dominance might impose fewer constraints on social choices, tolerance is

177 ced in vitro damage if an overnight delay is imposed following damage induction.

178 the maximal cost the Lightning ecosystem may impose for a given average volume of transactions.

179 This stimulus variability imposes fundamental external limits on the human ability

180 in realistic quantum communication channels imposes fundamental limits on the communication rates of

181 energy functions and their stochastic nature imposes generation of a large number of decoys to explor

182 nt for individual immune parameters, thereby imposing genetically regulated 'immunologic structures',

183 ould be observed not only in the presence of imposed gradients of secondary nutrients but also in ini

184 The oxidation of antioxidants by oxidizers imposes great challenges to both living organisms and th

185 to "fine-tune" their conformations, e.g., by imposing greater rigidity, by subtly altering certain si

186 ior during both voluntary motionlessness and imposed head fixation exposed a backward redistribution

187 We also uncover the features that impose high fidelity during the nucleotide-incorporation

188 ing frequency activity of PV(+) interneurons imposes high-energy demands on their metabolism that mus

189 Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020.

190 The support for such endogenously imposed interdependence, however, reduces when individua

191 Since our modifications do not impose intricate manufacturing, require long post-proces

192 and restricting populations to their homes, impose large and visible costs on society; however, thei

193 Size heterogeneity has traditionally imposed large challenges to energy quantification becaus

194 y of current manufacturing techniques, which impose limitations on their size and aspect ratio.

195 Although imposed limitations on availability may be rational cons

196 ly systems, but ultimately spatial distances impose limits on the effect, resulting in delegation of

197 constraint of the networks and whether they impose limits to molecular phenotypes remains elusive.

198 ound that rare ecosystems with active, human-imposed management suffered less damage in a hurricane's

199 mples for one country that initially did not impose measures and one that responded with a severe loc

200 Tissues undergoing morphogenesis impose mechanical effects on one another.

201 ich is further analyzed as a function of the imposed modulation.

202 ustment following 15 years of experimentally imposed moisture deficit.

203 PT neurons impose motor bias via a projection through the habenular

204 ly to inhibit projection neurons and thereby impose network gain control, an important but purely mod

205 Shifting climate patterns may impose novel combinations of abiotic conditions on anima

206 rsal in the central carbon flux owing to the imposed nutrient shifts.

207 e obligatorily occurs in the context of host-imposed nutritional immunity.

208 stacles that the exceptional features of Env impose on the creation of a successful HIV-1 vaccine.

209 ces homogeneous selection which is primarily imposed on Bacillales.

210 important driver of resistance is selection imposed on bacterial populations that are not the intend

211 ndings reveal how the mechanical environment imposed on cells within a tissue alters the molecular an

212 e mesostructures appear owing to constraints imposed on diffusion by the hexagonally arrayed pillar t

213 ak evidence that propensity to discount cost imposed on drug seeking is associated with dependence se

214 compulsion driven by insensitivity to costs imposed on drug seeking.

215 st for genetic and developmental constraints imposed on flower evolution in the context of the selfin

216 g fisheries value chains due to restrictions imposed on human movements in many countries.

217 iprocal relationship between the constraints imposed on the activation loop position and the affinity

218 ity and stability to limit mechanical stress imposed on the ER membrane.

219 ither a unitary "pacemaker" timing signal is imposed on the hippocampal system, or it may assist in o

220 confined fluidity and curvature constraints imposed on the lipid bilayer components of the cell memb

221 ) irrespective of the number of contractions imposed on the myofibrils and their initial sarcomere le

222 fitness to assess the strength of selection imposed on the nuclear genome by alternate mitochondrial

223 er to sustain the basal and pulsatile forces imposed on their walls throughout life.

224 limation in conifers and evaluate challenges imposed on them by changing climate and discuss emerging

225 la adapts to the challenges oxidative stress imposes on membrane bioenergetics by shifting redox bala

226 e adverse effects higher economic inequality imposes on them.

227 Furthermore, CDK-imposed order in the construction of the new SPB promote

228 C constantly limits growth cone exploration, imposing ordered and forward-directed progression throug

229 he distance-restraints (DR) and the Symmetry-Imposed Packing (SIP) filters.

230 The artery has an imposed peristaltic deformation and the deformable brain

231 initially quiescent and no external flow is imposed, persistent flows are generated along the solid

232 heir ability to find mates when ambient flow imposes physical constrains on their motion and impairs

233 Nanoconfinement imposes physical constraints and chemical effects on rea

234 isticated cyber-physical system to sense and impose post-anthesis HNT stress uniformly through physio

235 change over the next century is predicted to impose pressure on these areas, particularly around the

236 n debilitates the genuine stem-cell state by imposing primed-state features via FoxO inhibition.

237 atinum particles within the zeolite crystals impose pronounced diffusion limitations on reaction inte

238 Surface coal mining and processing impose public health risks on residential communities th

239 ls as bestowing relative benefits instead of imposing relative harms.

240 r bodies, as part of the intrinsic defenses, impose repression on incoming DNA.

241 that a flavivirus can mutate to escape RTP4-imposed restriction, and that diverse mammalian RTP4 ort

242 enarios obtained by selectively relaxing the imposed restrictions and total about 200,000 individuals

243 acy of nuclear pore complex (NPC) biogenesis imposes risks of failure that can cause defects in nucle

244 Thus, amoebae-imposed selection is a double-edged sword, having both p

245 results showed that antiviral gene silencing imposes selection in viral populations.

246 caused by the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effor

247 coronavirus disease 2019 (COVID-19) pandemic imposed severe restrictions on traditional methods of pa

248 tors used in organic photovoltaics (5-20 nm) imposes severe limits on the maximum size of the donor a

249 With the goal of imposing shape and structure on supramolecular gels, we

250 he contractile activity and of an externally imposed shear flow, we find three possible morphologies.

251 parasite Plasmodium falciparum continues to impose significant morbidity and mortality, despite subs

252 Brassica spp. crop diseases impose significant yield losses annually.

253 rly exposed to the pandemic but only Denmark imposed significant restrictions on social and economic

254 imicrobial resistance (AMR) in humans, which imposes significant health and economic costs on society

255 al partitioning of salt-affected watersheds, imposing significant constraints on water availability a

256 Using a replicated regression approach, we imposed single deluges that ranged in size from 20 to 12

257 In laboratory studies, imposed sleep restriction consistently reduces cognitive

258 level controls methane seepage variations by imposing smooth trends on timescales in the order of ten

259 corresponding to before and during pandemic imposed social restrictions, were screened for mood symp

260 displays and digital micromirror devices can impose spatial light modulation and actively shape light

261 Their architectural complexity and size impose specific demands on their members requiring adapt

262 ccommodate mechanical stretching rather than imposing strain into the materials directly.

263 To this end, California has imposed strict regulations on light-duty, medium-duty, a

264 ultiple features of bacterial promoters that impose stringent requirements on CRISPRa target sites.

265 en rates for European countries that quickly imposed stringent public health controls and those for c

266 site is distal from the polymerization site, imposing stringent structural and kinetic requirements f

267 ) Li] 3Dy and show that dicarbollide ligands impose strong magnetic axiality on the central Dy(III) i

268 r, higher aerobic activity and genetic drift impose strong mutation pressure and risk of irreversible

269 es the ability of bacteriophages (phages) to impose strong selection on their bacterial hosts: instea

270 thetic herbicides over the past 70 years has imposed strong and widespread selection pressure, leadin

271 traits, due to the likely violation of their imposed strong assumptions for causal inference.

272 rangement of the putative DNA-binding domain imposed strong constraints on how TerS(P76-26) can bind

273 ses animals from predation pressure and then imposes strong anthropogenic selection on traits.

274 fitting as well as more complex methods that impose structure (such as a multibody representation) on

275 zation procedure that manifests itself as an imposed structure on the observational data.

276 d by a deamidase, which, together with MavC, imposes temporal regulation of the activity of UBE2N dur

277 d other cellular stressors and therefore can impose temporary stress-induced constraints on the growt

278 als, gestation and lactation are expected to impose the major costs of reproduction, driving reproduc

279 HF in combination with any other diagnosis imposed the greatest risk of death and decrease in life

280 In response, the regional authorities imposed the lockdown of the whole municipality for 14 da

281 The closed geometry of the canal imposes the average flow rate to be null, explaining the

282 in the same Cmcm space group, while the DMA imposes the Ccmb space group.

283 oid the energy penalty that would arise from imposing the gg conformation on galacto-configured ligan

284 rpm) inside the droplet with the help of an imposed thermal gradient.

285 By imposing thermal and temporal control of the orthogonal

286 egular pattern of fibers in the filter paper imposes tortuous, highly variable boundaries during the

287 ed for SA biosynthesis, while releasing TDP1-imposed transcriptional repression on WRKY33, a master r

288 in TYROSYL-DNA PHOSPHODIESTERASE1 (TDP1), AN imposes transcriptional repression on MYB46, encoding a

289 es and developmental signaling pathways that impose underlying functional lateralization on a broadly

290 ion is imperfect as it lacks specificity and imposes unintended adverse effects such as opportunistic

291 ary language usage [1, 2]; its poetic genres impose unique combinatory constraints on linguistic elem

292 ctures among anthropoids suggest that fusion imposes unique constraints on masticatory function elsew

293 , increasing the risk of adverse effects and imposing unnecessary costs in healthcare.

294 imonious model that depicts rhythmic control imposed upon basic mRNA expression and poly(A) regulatio

295 the top material to sustain the polarization imposed upon it by the underlying layer, and these effec

296 ructure determination beyond the limitations imposed upon synchrotron measurements by radiation damag

297 re and more stringent requirements are being imposed upon the established equilibria among these LIB

298 puts, outputs, and architectural constraints imposed were sufficient for recapitulating processing in

299 of persons exposed to the virus needs to be imposed within 2 days to prevent a broad outbreak, where

300 CP inhibits GAS growth in vitro by imposing zinc (Zn) limitation.