ライフサイエンスコーパス: impractical

1 imentally characterizing all modified NNs is impractical.

2 n human cellular models have previously been impractical.

3 eologic methodologies are time consuming and impractical.

4 cquisition and processing, but this is often impractical.

5 g drugs soon after infection, which is often impractical.

6 r the direct measurement of these species is impractical.

7 novative; existing definitions are vague and impractical.

8 on is infected, making universal eradication impractical.

9 s is unknown because direct observations are impractical.

10 a for identifying those with sepsis would be impractical.

11 haracterization of epidermal cell parameters impractical.

12 ability, and graft removal by hepatectomy is impractical.

13 mmonly co-occur, making a dualistic approach impractical.

14 s where high-resolution surface alignment is impractical.

15 ries for riboswitch function in intact cells impractical.

16 system observables which would otherwise be impractical.

17 er systems for which more direct methods are impractical.

18 nical trials to establish the best treatment impractical.

19 he score and LR tests can be computationally impractical.

20 fying the loci contributing to a given trait impractical.

21 in situations where corneal measurements are impractical.

22 haustive searches for structures of interest impractical.

23 m the more intensive infusional regimens are impractical.

24 structure determination may in many cases be impractical.

25 licated models required can make computation impractical.

26 y and conduction, but to date remain largely impractical.

27 monomers makes exhaustive oligomer libraries impractical.

28 administration, but this route is clinically impractical.

29 g all samples upon each new arrival would be impractical.

30 on of all the database networks with a query impractical.

31 ion; but such approaches are computationally impractical.

32 s of thousands of eukaryotic species remains impractical.

33 numbers of sequences in this way is clearly impractical.

34 is uncertain because serial observations are impractical.

35 atalysis on the relevant timescales has been impractical.

36 ade such global studies either impossible or impractical.

37 gs in which ligand isotope-labeling is often impractical.

38 ion makes the synthesis of these biopolymers impractical.

39 s long, directly studying aging in humans is impractical.

40 rated by singlet oxygenation of linloeate is impractical.

41 chine size, and cost have made this approach impractical.

42 virus in every eligible individual would be impractical.

43 implementing all possible mismatch probes is impractical.

44 ng only cases, when finding good controls is impractical.

45 , especially in settings where microscopy is impractical.

46 exponentially, which renders manual curation impractical.

47 e low throughput, making a genome-wide study impractical.

48 l of the FDR at a preselected level is often impractical.

49 wavelengths such as erbium:YAG are currently impractical.

50 ation of recessive, loss-of-function alleles impractical.

51 t erbium:yttrium-aluminium-garnet fibers are impractical.

52 thermodynamic study of each possible variant impractical.

53 t were previously considered computationally impractical.

54 s of expression profiling that are currently impractical.

55 nsgenic animals for each gene of interest is impractical.

56 m by use of a conventional congenic approach impractical.

57 n-hospital monitoring to steady state highly impractical.

58 dividual assessment of C-peptide kinetics is impractical.

59 niques developed to identify CD8+ T cell Ags impractical.

60 for HRV estimation when ECG measurements are impractical.

61 m individually, but this has so far remained impractical.

62 olecular dynamics can prove to be inherently impractical.

63 more variable rhythms prevail, has remained impractical.

64 obtaining more refined experimental data is impractical.

65 ikingly narrow HT temperature window that is impractical.

66 iples approach to synthesizability currently impractical.

67 ous viruses cause URTI, antiviral therapy is impractical.

68 t guidelines recommend five to six, which is impractical.

69 e plaque reduction neutralization testing is impractical.

70 r urine collections, but such an approach is impractical.

71 chemical synthesis of complex isoprenoids is impractical.

72 , but this strategy will become increasingly impractical.

73 from three different channels, circumventing impractical 4D Fourier Transforms of the entire megapixe

74 otease-substrate combinations, which require impractical amounts of training data when expanding to s

75 systemic therapy in breast cancer make them impractical and even impossible to conduct.

76 However, commercialization is prevented by impractical and expensive THz instrumentation.

77 system memory (Random Access Memory) become impractical and out-of-core implementations are the only

78 , making repeated imaging of the same animal impractical and potentially affecting lymphocyte behavio

79 ntional synthetic compound libraries largely impractical, and actinomycetes, the main source of natur

80 mprove adherence have typically been costly, impractical, and at best only minimally successful.

81 NAFLD worldwide, liver biopsy evaluation is impractical, and noninvasive assessment for the diagnosi

82 ces, exact algorithms become computationally impractical, and progressive algorithms iterating pairwi

83 Culture for diagnosis is impractical, and seroconversion is often delayed after n

84 nst large numbers of cell lines is currently impractical, and such experiments are often difficult to

85 tandard; however, widespread testing remains impractical, and the development of in vitro assays that

86 However, identifying network hubs is often impractical, and they can be misleading if monitored for

87 wild-caught mosquito remains a challenging, impractical, and unreliable process.

88 reas where replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout b

89 hown by DFT, the noncoordinating nitrogen is impractical as a base in water oxidation catalysts due t

90 the slow growth habit of B. braunii makes it impractical as a production system.

91 for every combination of observables becomes impractical as the number of dimensions increases.

92 emains the gold standard for diagnosis it is impractical at a population level.

93 se technical hurdles make mutation discovery impractical at low-mutation frequency levels (<10(-2)).

94 the Ru-peroxo bonds, however, is found to be impractical at room temperature, with a barrier of Delta

95 l characterisation of WbmF, WbmG and WbmH is impractical at the present time.

96 s, monitoring all drinking water supplies is impractical because financial resources and capacity are

97 Not only are prospective trials impractical because of the emergent nature of the issue

98 achievement of target doses in humans proved impractical because of the large number of injections re

99 for conventional fluctuation analysis proved impractical because of the rapid rundown of calcium chan

100 in cases where more advanced methods may be impractical because of their extremely long computationa

101 signal processing is generally deemed to be impractical because optical nonlinearities are usually w

102 Masking of clinicians to PICC allocation was impractical because rifampicin caused brown staining of

103 Convalescent-phase serology is impractical, blood culture is slow, and many pathogens a

104 e side, make (79/81)Br and (127)I NMR rather impractical but turn NQR into a high-resolution probe of

105 sence of homologous human enzymes makes them impractical candidates for drug development.

106 ne can now approach structures of previously impractical complexity.

107 either fail dramatically, or else can impose impractical computational burdens due to numerical integ

108 modality has been limited by inefficient or impractical delivery systems.

109 nal antibodies using conventional methods is impractical due to high costs.

110 eezing without nucleation sites, making FTVs impractical due to instrument engineering challenges.

111 of these large datasets using R are becoming impractical due to large memory requirements.

112 olyzes one unique substrate, however this is impractical due to off-target promiscuity (i.e., one pro

113 f qubits is increased, this approach becomes impractical due to the footprint and complexity of the c

114 ls for which conventional solid-state NMR is impractical due to the lack of sensitivity.

115 typical mammalian cells has been found to be impractical due to the large size of mitochondria relati

116 ividual specimens has proven challenging and impractical due to, in part, a singleplex nature of repo

117 tment's various complications along with the impractical duration and depth of therapy significantly

118 ies are either limited in scope or are of an impractical duration for routine testing.

119 Column purifications are impractical during procedures involving multi-gigabecque

120 by PTR-ToF-MS, such a procedure could become impractical, especially when standards are not readily a

121 search replicates, but further search proved impractical even with grid computing.

122 normous computational cost such analyses are impractical, even for high-end computers.

123 d description of the solvent, which would be impractical for all conformations and sites sampled in t

124 ts and occasional convergence issues make it impractical for analyzing high-throughput data.

125 of these reagents is so large that it can be impractical for any one lab to stock everything they mig

126 ributions in density make these microspheres impractical for applications demanding small steps in de

127 examinations are costly, time-consuming, and impractical for assessing population-level needs.

128 osing is recommended for children in VF, but impractical for automated external defibrillator (AED) u

129 ological species, and hence, ACET may become impractical for biomicrofluidic sensors and other possib

130 observed in nature, yet current methods are impractical for characterizing the molecular basis and f

131 lantation is required, making such protocols impractical for clinical application.

132 890 degrees C substrate temperate is impractical for commercial device manufacturing due to l

133 0 kHz) and low frequency (30-300 kHz) ranges impractical for decades.

134 onics and microelectromechanical systems, is impractical for defining feature sizes below 0.1 microme

135 Phosphoprotein IHC have been impractical for diagnostics due to inconsistent results

136 However, long-term storage is impractical for Drosophila, so mutant strains must be ma

137 standard test statistics are computationally impractical for even moderate-sized genome-wide associat

138 This makes their use impractical for high throughput drug discovery platforms

139 nentially with the number of hits, making it impractical for identifying combinations of more than tw

140 and the nonhuman primate model are generally impractical for investigation of the bacterial mechanism

141 , but it leads to long runtimes that make it impractical for large count data common in bioinformatic

142 uting ACS(k) takes O(n logkn) time and hence impractical for large datasets, multiple heuristics that

143 putationally intensive MCMC methods that are impractical for large datasets.

144 on phylogenetic evidence has previously been impractical for large numbers of genomes at once, due to

145 low-throughput technique, making it largely impractical for large-scale measurements such as cell ty

146 This becomes impractical for larger proteins, and especially for prot

147 l phononic crystals, but Bragg scattering is impractical for low-frequency wave control because of th

148 mperatures (more than about 1,300 kelvin) is impractical for many applications.

149 f sub-chains; such a running time scaling is impractical for many applications.

150 ) has been the gold standard approach but is impractical for many clinical laboratories and is often

151 n the order of tens of thousands that can be impractical for many diseases or may lower the quality o

152 This procedure is clinically impractical for many patients with pulmonary fibrosis, a

153 positron emitter carbon-11, which is rather impractical for many PET centers.

154 on emitted spreads along a "cone", making it impractical for most applications.

155 rge size of commercial setups have made them impractical for most basic research.

156 loading of typically <1 wt.%, which is often impractical for most clinical applications.

157 n susceptibility testing, but this method is impractical for most clinical microbiology laboratories.

158 rate false alarms, such predictions would be impractical for most modern industrialized cities.

159 ire significant manual intervention, and are impractical for multiple genomic datasets in high-throug

160 ned by computational demands and thus become impractical for multiscale problems.

161 kinetic information in most buffers but was impractical for NO analysis in proteinaceous media.

162 g the available diagnostic methods, many are impractical for point-of-care field testing.

163 electivities without parametrization but are impractical for predicting small changes in selectivity.

164 s confirmed, that shorter devices are rather impractical for production sequencing applications when

165 ccuracy of base-calls on these platforms are impractical for production use due to their computationa

166 ent bisulfite sequencing platforms make them impractical for quantifying locus-specific RE methylatio

167 are optically driven with lasers, which are impractical for quantum computing owing to the bulk and

168 cially for recently infected animals, or are impractical for rapid field diagnostic applications.

169 ols to study concussion biomechanics but are impractical for real-world use because they are too slow

170 t with recombination has conventionally been impractical for regions beyond tens of megabases.

171 scale, this is both very time-consuming and impractical for repeated explorations with standard mark

172 ity, but remain high-complexity technologies impractical for RLS.

173 d molecules is computationally expensive and impractical for routine NMR-restrained calculations that

174 served loci) and whole-genome sequencing are impractical for routine use.

175 ng of individual 2D TMD layers, which remain impractical for scaled-up applications.

176 ristic of lipid I renders MurX enzyme assays impractical for screening and lacks reproducibility of t

177 o very early death and makes this mouse line impractical for studying the pathobiology of mitochondri

178 f stem cells within the adult CNS makes them impractical for surgical removal and autologous transpla

179 on whole-genome deep sequencing is currently impractical for the purpose of routine clinical care.

180 g wires for signal transduction, but this is impractical for the readout of individual nanoparticles.

181 stress, or temperature, such methods can be impractical for thin films and do not capture informatio

182 g germination of superdormant spores but are impractical for use in a hospital setting, where Clostri

183 asive nature of fine wire electrodes, EMG is impractical for use outside of a laboratory environment.

184 nd other well-recognized limitations make it impractical for widespread use given the overall NAFLD d

185 ls without rotating the sample, which can be impractical, for instance for samples held in a cryostat

186 would enable the rapid assembly of currently impractical genotypes that involve multiple homozygous g

187 plete transduction of the entire heart is an impractical goal, it becomes critical to determine the m

188 g these newer approaches are inconclusive or impractical, however, catheter-based techniques are stil

189 deliver such coverage can be undesirable and impractical; however, endangered populations are increas

190 dy of lymphoid phenotypes can be obscured or impractical if homozygous mutations cause early embryoni

191 al connectivity from functional connectivity impractical; (ii) that indirect connections and interreg

192 Our results suggest that, when it is impractical/impossible to determine whether tests were c

193 us observation of livestock by farm staff is impractical in a commercial setting to the degree requir

194 It will clearly be impractical in acids that are weaker still.

195 ese methods in predicting overt HE, many are impractical in clinical practice, and test cutoffs relev

196 Three-dimensional microscopy is therefore impractical in clinical settings and often limited to co

197 cooling, which is generally inefficient and impractical in clinical situations.

198 over hundreds of shots, which is ordinarily impractical in conventional shock tube studies.

199 tology and require multiple visits have been impractical in developing countries.

200 y approaches to the management of aflatoxins impractical in developing-country settings, but the stra

201 ormously computation-time intensive and thus impractical in high throughput studies, informatics-base

202 eview for confirmation of an RA diagnosis is impractical in large cohort studies, the current study (

203 iopsy studies that cause scarring and may be impractical in large-scale clinical trials.

204 However, such specification is difficult or impractical in many scenarios.

205 identify the absence of body iron stores is impractical in most cases.

206 ovision of sanitation and water treatment is impractical in most developing countries, where morbidit

207 Mammographic screening is impractical in most of the world where breast cancers ar

208 n academic departments of psychiatry that is impractical in primary care settings because it takes to

209 n requires a multitude of laboratory assays, impractical in real-time clinical settings, where the in

210 tal for antibiotic treatment, which is often impractical in resource-limited settings.

211 tal for antibiotic treatment, which is often impractical in resource-limited settings.

212 can be costly, time-consuming and are often impractical in rural and resource-poor regions in China,

213 primary method for gene cloning, but this is impractical in several situations, for example, when the

214 tantial loss of precious information, and is impractical in situations where virtually all markers (e

215 DFT optimization of H atom positions is impractical in structural biology studies.

216 ndicates that a 1 km screening radius may be impractical in such resource limited settings such as Sw

217 tery but its instability towards Na makes it impractical in the Na-O2 battery.

218 observations of early pretumor mutations are impractical, it may be possible to retrospectively recon

219 B(NDippCH)2} (1, Dipp = 2,6-iPr2C6H3) render impractical its use for the direct introduction of the {

220 me (6 months to sexual maturity) makes it an impractical lab model and has prevented it widespread us

221 accination against the toxin undesirable and impractical, leading to intensified efforts to develop e

222 sor syntheses, the separation of isomers, or impractical limitations of the scale.

223 of the brain, which necessitates clinically impractical long image acquisition times.

224 onses into strong signals so that ordinarily impractical measurements become possible.

225 nical practice and research studies is often impractical, necessitating short-item if not single-item

226 Moreover, simulations reveal that an impractical number of 1-ha field plots (from 10 to more

227 esponse surface are desirable but require an impractical number of data points.

228 es may exclude biophysical detail due to the impractical number of state combinations that arise when

229 cellular heterogeneity, but it is currently impractical on large sample cohorts and cannot be applie

230 herapy when other anaplerotic substrates are impractical or contraindicated, e.g. in propionic acidem

231 idual in early stage of sequence analysis is impractical or even impossible for large-scale sequencin

232 ard antibodies or their derivatives would be impractical or impossible.

233 tions when existing genome-based methods are impractical or ineffective.

234 s as well as to perform experiments that are impractical or not feasible in vivo or in vitro.

235 tically ill patients have been assumed to be impractical or not feasible.

236 ical point of care, instrumentation might be impractical or unavailable.

237 there are many circumstances in which it is impractical or undesirable to insert objects or subjects

238 ration step prior to mass analysis is either impractical or undesirable.

239 e high-resolution NMR is either unnecessary, impractical, or both, as is the case in the emerging fie

240 nutritional exposures are often impossible, impractical, or unaffordable.

241 Mitigating therapies, aside from impractical organ transplantation, remain limited and th

242 DNA sequence from sub-nanogram quantities is impractical owing to inefficient delivery of DNA molecul

243 yet large-scale metastasis research has been impractical owing to the complexity of in vivo models.

244 modification of the human genome in vivo is impractical owing to the low frequency of homologous rec

245 s for clinical use as combination therapy is impractical, owing to regulatory hurdles and cost.

246 icles and alpha-like nuclei have so far been impractical, owing to the exponential growth of the numb

247 s, with traditional tools could be risky and impractical, particularly on large collections of import

248 Mortality is an impractical primary endpoint for clinical trials in pati

249 main for widespread AAV utilization, such as impractical purification strategies and low viral quanti

250 However, this approach often requires impractical reagents, such as IOAc, or strong co-oxidant

251 Perhaps the most important obstacle is the impractical requirement of multiple blood samples to ade

252 e providing treatment to malaria patients is impractical, researchers need molecular markers of resis

253 a series of challenges, two of which are an impractical, separated management of wildlife and outdat

254 Such potential would be impractical since the theoretical potential of the catho

255 bandwidth of operation because they require impractical sizes and masses.

256 d heterogeneous in structure, making them an impractical solution.

257 t nonlinear ultrasonic methods still involve impractical solutions such as cumbersome signal calibrat

258 traps limit the speed of such detectors, and impractical strategies, e.g., the use of large gate-volt

259 in circumstances where liquid lubricants are impractical, such as in space technology, ultra-high vac

260 The complex and impractical techniques for the measurement of GFR have l

261 ll line facilitates the following previously impractical techniques: high-throughput screening for ag

262 tives and exposes some alternatives to be so impractical that they are almost fraudulent.

263 ry path for long decision sequences is often impractical; thus, cognitive shortcuts are often essenti

264 ni and false discovery rate (FDR), are often impractical to apply, as a majority of the causal varian

265 vailable in the GM12878 cell line, making it impractical to compare subcompartment patterns across ce

266 of elderly adults are limited, because it is impractical to conduct repeated nitrogen balance protoco

267 ergy landscape that would be computationally impractical to do via Molecular Dynamics.

268 far smaller than the total population, it is impractical to exhaustively characterize diversity of mo

269 Since it is impractical to experimentally assess all candidate neoep

270 until now it has been difficult, costly, and impractical to fabricate such nanowires in proper alignm

271 to those of standards; however, it is often impractical to have standards on hand for every compound

272 As studied, these strategies are often impractical to implement, as they typically assume compl

273 and absence of black/gray states and/or are impractical to integrate with actively addressed electro

274 red to complete the immunizations, making it impractical to limit an acute epidemic.

275 resources available, but it quickly becomes impractical to manually access and review all of these s

276 nsiveness to inhaled corticosteroids but are impractical to measure in primary care.

277 r (PM) component of HAP, but it is currently impractical to measure personal exposure to PM in large

278 ible to test hypotheses that were previously impractical to model.

279 As a consequence, it has been impractical to obtain accurate thickness estimates for t

280 itions (e.g., 3-5 years) and therefore it is impractical to obtain complete release profiles (e.g. th

281 Although tissue biopsies are impractical to perform routinely in the majority of pati

282 osition component that remains difficult and impractical to quantify by most investigators outside of

283 Since it is impractical to screen all possible drug combinations for

284 cies of risk alleles in tissue banks make it impractical to study their function in cells derived fro

285 Because it is impractical to test each molecule/labyrinth pair using c

286 sments consider multiple stressors but it is impractical to test every chemical combination to which

287 Given that it is impractical to use FIB-SEM brain-wide, we used previousl

288 ike clinical trials for exudative AMD, it is impractical to use the change in visual acuity (VA) as a

289 new and standard cut-points, which makes it impractical to use the new ones on a population that inc

290 Room-temperature sodium metal batteries are impractical today because morphological instability duri

291 derstanding of candidal pathogenesis, but is impractical using existing techniques.

292 high sensitivity and specificity, but IFA is impractical, variably reproducible, and cumbersome for l

293 ive exon usage (AEU) using such data require impractical visual inspection and still yield high false

294 Because long-term field studies are impractical, we used known behavior of male and female G

295 the drug combination effects, yet it becomes impractical when the number of drugs under consideration

296 gh charge carrier mobilities but are usually impractical, whereas polymers have good processability b

297 anodiamonds under vacuum may make the method impractical with currently available materials.

298 n of the signals is still required, which is impractical with large datasets.

299 ial scales for ~1 ns, which is prohibitively impractical with QM.

300 ogistics render 2-dose immunization regimens impractical would be a major advance.PXVX0200, based on