ライフサイエンスコーパス: in high yield

1 ring closure to afford a representative GSM in high yield.

2 continuous-flow syntheses of small molecules in high yield.

3 n, furnished the target nucleoside FMCA (12) in high yield.

4 f the C-H activation to form this tetracycle in high yield.

5 are synthesized by this single-step approach in high yield.

6 carbon centers can be synthesized easily and in high yield.

7 degradation and is challenging to synthesize in high yield.

8 1 with high regio- and diastereoselectivity in high yield.

9 m the A/B/C/D rings of (+/-)-minfiensine (2) in high yield.

10 t synthesis of alkyl-substituted acylsilanes in high yield.

11 omplex [Cu2(mu-eta(1):eta(1)-Ph)DPFN](NTf2)2 in high yield.

12 erize alkynes to form conjugated macrocycles in high yield.

13 on in the nucleoside's excited triplet state in high yield.

14 versity of new thioether (hetera)cyclophanes in high yield.

15 eCN at room temperature produced imidazoline in high yield.

16 nsfer to provide the corresponding fluorides in high yield.

17 to a cycloparaphenyleneacetylene derivative in high yield.

18 yrosine peptides into sulfotyrosine peptides in high yield.

19 tic process and to obtain the target protein in high yield.

20 tion the corresponding adducts were obtained in high yield.

21 nous acetylation at multiple lysine residues in high yield.

22 OH to give Boc-protected alpha-aminopyrroles in high yield.

23 sulating precursor under mild conditions and in high yield.

24 zimidazoles or 1,4,6,9-tetramethoxyphenazine in high yield.

25 -catalyzed Suzuki coupling with boronic acid in high yield.

26 t then couple to N-terminal proline residues in high yield.

27 c 1,2-diketones to deliver amides and imides in high yields.

28 with TMDS to give the corresponding enamines in high yields.

29 he homoleptic Cu(I) complex were synthesized in high yields.

30 lation products were efficiently synthesized in high yields.

31 mides and biphenyl-2,2'-dicarboxamide motifs in high yields.

32 conditions to provide corresponding adducts in high yields.

33 strates to achieve oxidative transformations in high yields.

34 stereocontrol, leading to beta-amino ketones in high yields.

35 nt Lys, Cys, and Tyr residues in thioredoxin in high yields.

36 ysis to form the corresponding NH tetrazoles in high yields.

37 ) atmosphere to deliver the target molecules in high yields.

38 ing fused pyrrolecarboxylic acid derivatives in high yields.

39 Tf, SPh), cleanly affords (R3 SiO)2 UX2 (L)2 in high yields.

40 aryl substituents, were successfully reacted in high yields.

41 ent, ene reaction, and O-alkylation occurred in high yields.

42 access a variety of imides as well as amides in high yields.

43 s to produce C(sp(2))-H alkoxylated products in high yields.

44 and C-C bonds and gives unique metallacycles in high yields.

45 ve highly substituted 4-nitro-4-isoxazolines in high yields.

46 -containing hypervalent iodine(III) reagents in high yields.

47 acetonitrile underwent reductive elimination in high yields.

48 which the bridgehead nitrones were isolated in high yields.

49 or 3-bromobipyridine N-oxides were obtained in high yields.

50 uence furnishes quadruply annulated borepins in high yields.

51 f C(sp(3))-S and C(sp(3))-N coupled products in high yields.

52 , affords enantioenriched gamma-fluoroamines in high yields.

53 odides to provide the meta-arylated products in high yields.

54 and 0D (C4 N2 H14 Br)4 SnBr6 can be prepared in high yields.

55 e of Yb(OTf)3 to afford the desired products in high yields.

56 )-1H-1,2,4-triazole-5(4H)-thiones are formed in high yields.

57 a-Baylis-Hillman alcohols to give 1,4-dienes in high yields.

58 erocycles and oxoaldehydes under ambient air in high yields.

59 PEG-based crosslinker, which are synthesized in high yields.

60 extended to produce other layered materials in high yields.

61 es and 4-(1H-pyrrol-3-yl)-1H-1,2,4-triazoles in high yields.

62 tarting from 3-amino-2H-chromen-2-one, again in high yields.

63 onded phenolates hydroxylate to catecholates in high yields.

64 wed by air oxidation to furnish the products in high yields.

65 a variety of aliphatic [(18)F]CF3S compounds in high yields.

66 alkenyl or N-(o-thio)aryl group was obtained in high yields.

67 rnishing the fused indolo[2,1-a]phthalazines in high yields.

68 synthesised via Oxa-Pictet-Spengler reaction in high yields.

69 or site-specific incorporation into proteins in high yields.

70 ng cellular phospholipids have been obtained in high yields.

71 ) as a catalyst led to quinoline derivatives in high yields.

72 acilitate carboxylation to give the products in high yields.

73 temperature with a series of aryl chlorides in high yields.

74 ade provides highly substituted 2-oxazolines in high yields.

75 ters, to form aryl alkyl and dialkyl ketones in high yields.

76 ng anhydrides to provide alpha-cyanoacetates in high yields.

77 ylic alcohols to aldehyde or ketone products in high yields.

78 s the regioselective synthesis of oxazolines in high yields.

79 gars, to provide access to cyclic aminodiols in high yields.

80 hiles allows for chain-end functionalization in high yields.

81 sterically hindered substrates still couple in high yield (33 examples, 70% average yield).

82 lavenes and isoflavenes, and even coumarins, in high yields (59 to 91%, 32 examples).

83 trans-1-trifluoromethyl-2-arylcyclopropanes in high yields (61-99%) and excellent diastereo- and ena

84 ight irradiation to yield 2,3-fused pyrroles in high yields (68-84%).

85 tituted bicyclo[4.2.2]deca-2,4,7,9-tetraenes in high yields (68-85%).

86 -1-yl]-5H-1,2,3-dithiazol-5-ylidene}anilines in high yields (70-92%).

87 ly valuable bicyclo[4.2.1]nona-2,4,7-trienes in high yields (72-88%).

88 ugar poly(orthoester), directly from glucose in high yield (73 % from glucose).

89 toward this distinctive polymer architecture in high yield ( 75%) via efficient ring closing of ratio

90 providing the corresponding 4-oxopiperidines in high yields (80-89%).

91 c anhydrides of varying alkyl chain lengths, in high yields (80-95%).

92 and isolated in gram amounts (up to 5 g) and in high yields (80-96%) and characterized by NMR, ESI-HR

93 hydroxy-1,3-diaminoprop ane) was synthesised in high yield (90 %).

94 The peptide conjugations were carried out in high yield (90%) with their functional groups intact.

95 ransposed were synthesized regiospecifically in high yields (94 and 92%, respectively) by the Wang-Pe

96 raldehyde to give a 12:1 syn:syn selectivity in high yield along with small amounts of one anti isome

97 urification procedures that afford materials in high yield and avoid chromatographic purification.

98 We found that the anti adduct was obtained in high yield and diastereoselection as was demonstrated

99 a variety of cis-2,3-disubstituted indolines in high yield and enantioeselectivity.

100 atoboryl) substituent each were hydrogenated in high yield and enantioselectivity using C(1)-symmetri

101 ination to generate terminal alkyne products in high yield and excellent levels of enantiospecificity

102 aternary protected 2-amino-2-vinyl-1,3-diols in high yield and excellent stereochemical purity.

103 imple alkyl-substituted alkynes and Bu(3)SnH in high yield and good regioselectivity; these products

104 (89)Zr-labeling of Df-ALT-836 was achieved in high yield and good specific activity.

105 y prepared and isolated as the oxalate salts in high yield and high purity.

106 branched few-layered nanosheets are produced in high yield and in a reproducible and controlled manne

107 thyltetrazinyl functionality was synthesized in high yield and labeled endogenous MAGL in live cells.

108 an all-carbon-atom quaternary stereocenter, in high yield and optical purity.

109 eloped for the isolation of (223,224,225)Ra, in high yield and purity, from a proton irradiated (232)

110 Results: All new ligands were obtained in high yield and purity.

111 ation by aminating a large set of terpenoids in high yield and regioselectivity.

112 o 10 bar) was directly converted to methanol in high yield and selectivity in the presence of H(2) (7

113 rized radical addition to aromatic compounds in high yield and selectivity.

114 ition of the C-F bond, these reactions occur in high yield and selectivity.

115 sess three chiral centers have been prepared in high yield and stereocontrol from silyl-protected Z-g

116 re performed on the chiral benzylic alcohols in high yield and stereoselectivity.

117 arbene=:C[(Pr(i) )NC(Me)]2 ) was synthesized in high yield and structurally characterized.

118 n-poor, and sterically hindered aryl iodides in high yield and tolerates a variety of functional grou

119 tetracyclic tetralin analogues were prepared in high yield and up to 20/1 diasteroselectivity from cy

120 etic resolution afforded the target compound in high yield and up to 99% ee.

121 variety of functional groups are transformed in high yield and very high regioselectivity.

122 (18)F-SO3F(-) is easily synthesized in high yield and very high specific activity and is a p

123 heteroaryl, vinyl, or cyclopropyl aldimines in high yield and with excellent diastereo- (up to >20:1

124 imelteon, Ticagrelor, and a TRPV1 inhibitor) in high yield and with excellent diastereo- and enantios

125 c shift to afford the boronic ester products in high yield and with excellent enantiospecificity.

126 ucts containing indole-bearing stereocenters in high yield and with excellent levels of enantioinduct

127 The addition products are obtained in high yield and with excellent stereocontrol of the in

128 y disfavored alkenyl chlorides and fluorides in high yield and with exceptional stereoselectivity.

129 wide range of functional groups are obtained in high yield and with good regio-, diastereo-, and enan

130 Ugi adducts to give spiro-diketopiperazines in high yield and with high enantioselectivity.

131 e method produces all major species of ncRNA in high yield and with high integrity, enabling direct c

132 -dienophile reactive pairs proceeds rapidly, in high yield and with tunable stereochemical preference

133 lkene substrates to their respective alkanes in high yields and diastereoselectivities and introduces

134 ation of 1,2,3-substituted borocyclopropanes in high yields and diastereoselectivities.

135 ional groups to generate chlorocyclopropanes in high yields and diastereoselectivities.

136 diaryl and triaryl quaternary stereocenters in high yields and ee's.

137 lution, furnishing both epoxide and thiirane in high yields and enantiomeric purity.

138 at reactions of alpha-fluorotetralones occur in high yields and enantioselectivities when conducted w

139 rovides access to valuable beta-fluoroamines in high yields and enantioselectivities.

140 performed and yields versatile intermediates in high yields and enantioselectivities.

141 ta-lactones are formed under mild conditions in high yields and enantioselectivities.

142 In both cases, the products are obtained in high yields and enantioselectivities.

143 ridged dinitrogen heterocycles were obtained in high yields and excellent diastereo- and enantioselec

144 roviding attractive pyrrolo-azepine products in high yields and excellent enantioselectivities (99% e

145 with a N-containing quaternary stereocenter in high yields and excellent enantioselectivities.

146 or S-enantiomer of the chiral amine products in high yields and excellent enantioselectivities.

147 ecarboxylation and loss of acetone, proceeds in high yields and excellent enantioselectivity (up to 9

148 ide range of alkynes furnishing the products in high yields and excellent enantioselectivity.

149 yl-1,1,3,3-tetracyanopropenides (ATCN) salts in high yields and excellent purities starting from read

150 e corresponding aldol products were obtained in high yields and good to excellent diastereoselectivit

151 elivering the chiral barbiturate derivatives in high yields and high enantioselectivities, even with

152 tes activates this transformation to proceed in high yields and in a regio- and diastereoselective ma

153 stituted polycyclic dibenzofuran derivatives in high yields and in an atom-efficient and environmenta

154 The reaction proceeds at room temperature in high yields and is applicable to a broad range of sub

155 one substrates leading to the final products in high yields and providing excellent stereocontrol in

156 etrasubstituted stereocenter can be isolated in high yields and selectivities for further derivatizat

157 nitrile, while branched amides were obtained in high yields and selectivity in butanone by changing t

158 s the additives, linear amides were obtained in high yields and selectivity using tris(4-methoxypheny

159 ficient preparation of the arylated products in high yields and short residence times.

160 the formation of [Cp''2Zr(eta(1:1)-As4)] (1) in high yields and the arsenic-rich complex [(Cp''2Zr)(C

161 g stable precursors of alpha-hydrazinoimines in high yields and with almost complete enantioselectivi

162 ting vicinal chirality centers were obtained in high yields and with excellent enantio-, diastereo-,

163 II) additive enables the preparation of KATs in high yields and with good functional group tolerance.

164 carbo- and heterocyclic five-membered rings in high yields and with good to excellent diastereo- and

165 olecular silylation of cyclopropyl C-H bonds in high yields and with high enantiomeric excesses in th

166 be the preparation of cellulose nanocrystals in high yields and with minimal water consumption.

167 ctrum of homoallylic diazoacetate substrates in high yields and with up to 99 % enantiomeric excess.

168 phatic Grignard reagents at room temperature in high yields and within a few minutes' residence time,

169 ariety of pi-extended triptycenes accessible in high yields and without the necessity of column chrom

170 The reactions proceed in high yield, and functional groups such as halides, si

171 f the parent bridging amide produced ammonia in high yield, and treatment of the nitride with PhSH wa

172 eveloped to afford chromanone-3-carboxylates in high yields as a single diastereomer.

173 by polymer chemists to post-modify polymers in high yields, as well as to effectively catalyze rever

174 described acylimidazole reagents that react in high yields at 2'-OH groups stochastically at nonbase

175 a Hirao coupling occurred straightforwardly in high yields at positions 3, 5, and 6 of imidazopyridi

176 ng product [(Cp*Ir(NHC)Cl)2][(BAr(F)4)2], 4, in high yields at the end of the reaction suggests that

177 erto unreported products are easily isolated in high yield by a simple filtration step.

178 pyl esters and cyclobutyl esters is achieved in high yield by ensuring that the rate of coupling exce

179 e easily prepared with good size control and in high yield by reacting the metal precursors (copper i

180 polymers with benzothiadiazole were prepared in high yield by Suzuki polymerization to afford materia

181 terocyclic building blocks, were synthesized in high yield by the reaction of sodium azide with 2H-az

182 thesis of eudistidine C (1) was accomplished in high yield by treating eudistidine A (2) with 4(2-ami

183 phatic potassium acyltrifluoroborates (KATs) in high yields by treating the in situ formed tetracoord

184 romising sustainable intensification options in high-yielding cereal systems.

185 inputs during the green revolution resulted in high yielding cropping systems.

186 In high yield cultivar, the shoot growth was priority to

187 lates of azaaryl ketones, esters, and amides in high yield, diastereoselectivity, and enantioselectiv

188 of aniline, 3-hydroxyketones can be obtained in high yield directly from propargylic alcohols.

189 caused by increasing temperatures is higher in high-yielding environments (e.g., northern India) bec

190 ensification of biocatalysis as demonstrated in high yield esterifications and in the sesquiterpene c

191 ithin 30 minutes; and deliver their products in high yields, even on decagram scales.

192 omplex chiral secondary homoallylic alcohols in high yield, excellent diastereoselectivity, and usual

193 am scale-up to deliver 2-alkyl-N-arylindoles in high yields followed with only a single purification

194 sitive functional groups, undergo silylation in high yield for the first time, and arenes that underw

195 nion derived from a benzylic nitrile proceed in high yields for a variety of peroxides, including tho

196 FMRP, FXR1P, and FXR2P from Escherichia coli in high yields, free of protein and nucleic acid contami

197 nobenzylidene/aminoalkylidene)indolin-2-ones in high yield from 2-oxindole and aryl/alkyl nitrile in

198 The two key building blocks can be prepared in high yield from commercially available starting mater

199 on of phosphorylated diamantane was achieved in high yield from the corresponding phosphonates.

200 mino/hydroxythiophenes were readily obtained in high yields from easily accessible precursors, in a s

201 lkaloids, methylisatoid and cephalanthrin B, in high yields from simple precursors under mild and met

202 heptan-2-one-based tetracycles were obtained in high yield (generally >99%) and with excellent diaste

203 -group tolerance, and products were isolated in high yields, generally without the requirement for pu

204 photochemical deprotection was accomplished in high yields (>80%).

205 ep was completed in a short time (1-2 h) and in high yields (>90%), due to the intrinsic rigid struct

206 isoprene polymerization, leading to polymers in high yields (>95%) and with high (>90%) cis-1,4-polyi

207 product from a benzylic trichloroacetimidate in high yield have been developed.

208 At conditions relevant to mixing regions in high-yield implosions, we observe persistent chunks o

209 erved in the tandem reaction, which proceeds in high yield in 1-3 h.

210 e used in one pot and products were obtained in high yield in an easy workup procedure.

211 Cl2 with TPPO precipitates a TPPO-Zn complex in high yield in several common polar organic solvents.

212 meric, and cysteine-free and can be produced in high yields in a prokaryotic host, such as Escherichi

213 used pyridoindolone derivatives are obtained in high yields in a relatively short period of time unde

214 allows direct access to cyclic vinyl ethers in high yields in a single step.

215 azepines were obtained from these precursors in high yields in an alkylation/annulation sequence.

216 nchona alkaloid-derived dimers were obtained in high yields in copper-catalyzed 1,3-dipolar "click" c

217 (I)](+), transforms (*)NO((g)) to N(2)O((g)) in high-yields in methanol.

218 ent organic framework (COF) nanosheets (NSs) in high yield is of great importance for the further exp

219 tion of 3,3-disubstituted dihydrobenzofurans in high yields is described.

220 sults identify dG oxidation to d2Ih to occur in high yields leading to a hypothesis that d2Ih could b

221 The synthesis is achieved in high yields making use of an intramolecular direct ar

222 ting of a CGA moiety, caffeic acid, resulted in high yield of CO2 (>98%), suggesting that CGA hydroly

223 n hematopoietic stem cells (HSCs) can result in high yields of hematopoietic progenitor cells, this g

224 ults indicate that CO2 enrichment can result in high yields of red leaf lettuce rich in phenolic comp

225 d to label ATP and GTP site specifically and in high yields of up to 90%.

226 owed catalytic activity for the degradation (in high yields) of New Fuchsine (NF), Methylene Blue (MB

227 oupling reaction generally provides products in high yields, offers an expansive substrate scope, and

228 ionally reactive and are able to participate in high-yielding olefin metathesis reactions that afford

229 ed by a cofacial porphyrin scaffold accessed in high yield (overall 53%) using coordination-driven se

230 oad range of functional groups were obtained in high yields, regioselectivities, and diastereoselecti

231 tuted quinazolin-4(3H)-ones were synthesized in high yields starting from readily available benzyl al

232 d into 2-(9'-fluorenylmethyloxy)-2-oxazoline in high yield, thereby providing a new pathway for the s

233 itride with PhSH was found to liberate NH(3) in high yield through a reaction that engages the redox-

234 nyl-1,3-diazabicyclo[3.1.0]hexane structures in high yields through intramolecular radical aziridinat

235 lly appealing ortho-substituted biarylamides in high yields through unique carbonyl (CO) replacement.

236 tive C(sp(2))-H activation in aqueous medium in high yields to demonstrate the practicability of this

237 acid derivatives were subsequently converted in high yields to enantiopure beta-functionalized cystei

238 ure from 2H-azirin-2-carbonyl chlorides, led in high yields to the formation of 2-(diazoacetyl)pyrrol

239 or redox oxide catalysts to produce methanol in high yields, together with other useful chemicals, in

240 and lipid biosyntheses can be reconstituted in high yield under mild, prebiotically plausible condit

241 oxidation of benzylic alcohols to aldehydes in high yield under purely aqueous conditions, at room t

242 id synthesis of 1,3-substituted cyclobutanes in high yield under simple and robust reaction condition

243 he efficient release of homopiperonylic acid in high yield under simulated physiological conditions.

244 roxyiminoimines to trisubstituted imidazoles in high yields under mild conditions.

245 related biologically important heterocycles in high yields under mild conditions.

246 100 degrees C and affords fused heterocycles in high yields up to 99%.

247 ic properties to afford the desired products in high yield (up to 96 %) and high ee (up to 95 %).

248 tive alkynylation of trifluoromethyl ketones in high yield (up to 99 %) and high enantioselectivity (

249 arboxylic acids are isolated as sodium salts in high yields (up to 77%) by direct precipitation from

250 alumina converts various polyethylene grades in high yields (up to 80 weight percent) to low-molecula

251 ach delivers the desired molecular scaffolds in high yields (up to 82%) with excellent stereoselectiv

252 y of high-value olefin-tethered heteroarenes in high yields (up to 87%).

253 al groups and furnishes the desired products in high yields (up to 92%) with excellent stereoselectiv

254 e to furnish a wide range of propargylamines in high yields (up to 94%) and excellent enantioselectiv

255 diastereoselectivities (up to 98:2 d.r.) and in high yields (up to 96 %).

256 3,3,3-trifluoropropanes [Ar(Ar')CH-CH(X)CF3] in high yields (up to 96%) as a mixture of two diastereo

257 onalized indolines (18 examples) is obtained in high yields (up to 96%) under mild reaction condition

258 ering fully substituted unsymmetrical amides in high yields (up to 96%).

259 one products with excellent regioselectivity in high yields (up to 96%).

260 3-oxoisoindoline-1-acetamides (32 examples) in high yields (up to 97%).

261 yanated thiazoline and oxazoline derivatives in high yields (up to 97%).

262 ilylesters and alpha-thioesters was obtained in high yields (up to 98%) from alpha-diazoesters using

263 for downstream derivatisation were obtained in high yields (up to 99 %) and consistently high enanti

264 tion of intermolecular C-O coupling products in high yields, up to 92%, using DMSO as a solvent with

265 alkenes to furnish aldehydes and/or ketones in high yield using a low catalyst loading in the water.

266 sizes and heteroatoms have been synthesized in high yield using this mild acid-catalyzed reaction.

267 rated to provide the corresponding compounds in high yields using a simple one-pot procedure.

268 ased inclusion compound has been synthesized in high yields using an innovative and proficient acoust

269 permits the preparation of target compounds in high yields using readily available arylhydrazines an

270 first independent generation of dG(N2-H)(.) in high yield via photolysis of 1.

271 ylenediimide (AzaBPDI) dyes were synthesized in high yields via a new reaction sequence involving an

272 tonate) have been obtained on a large scale, in high yield, via one-pot reaction that utilizes commer

273 of unprecedented [3]naphthylene regioisomers in high yields, where three naphthalenoids are fused thr

274 The reaction proceeds in high yield with as little as 1000 ppm catalyst loadin

275 active secondary alcohols could be obtained in high yield with good to excellent enatioselectivities

276 lting chiral products are typically obtained in high yield with good to excellent levels of enantiose

277 ve alkaloid-inspired tetrahydroindolizidines in high yield with high diastereoselectivity.

278 nd we identified variants that were modified in high yield with no reduction in thermostability.

279 mates with electrophilic metalloenolcarbenes in high yield with up to 98 % ee and excellent diastereo

280 uble C-O coupling products chemo-selectively in high yields with a broad substrate scope.

281 These reactions proceed smoothly and in high yields with both enolizable and non-enolizable s

282 C bond formations with imines have proceeded in high yields with complete regioselectivity and excell

283 synthesis of substituted cyclic sulfoximines in high yields with complete stereocontrol, and tolerate

284 nditions, the desired products are delivered in high yields with ee values of up to 98 %.

285 s, affording the corresponding cyclopropanes in high yields with effective control of both diastereo-

286 d acetals, ketals, or aminals have proceeded in high yields with essentially complete regio- and chem

287 The reactions form dihydrobenzosiloles in high yields with excellent enantioselectivities by fu

288 a CF(3)-substituted quaternary stereocenter in high yields with excellent enantioselectivities.

289 oped to achieve these bond forming processes in high yields with excellent stereocontrol, but few off

290 substituted and functionalizable piperazines in high yields with excellent stereoselectivity (de, ee

291 ing protected alkyl, alkenyl and aryl amines in high yields with gaseous N(2) and CO(2) as the only b

292 alized 5-membered chiral cyclic sulfonamides in high yields with high enantioselectivities.

293 quaternary stereogenic centers were isolated in high yields with high to excellent enantioselectivity

294 reogenic center through remote stereocontrol in high yields with moderate to excellent enantioselecti

295 flate, Mannich addition products were formed in high yields with near exclusivity under otherwise ide

296 acetate substrates were efficiently cyclized in high yields with up to 99% enantiomeric excess.

297 lkyl disubstituted cyclobutyl boronic esters in high yields, with full stereospecificity and high lev

298 The cycloadditions proceeded in high yields, with the cyclophane reacting faster than

299 gives water-soluble altrose PASs (alt-PASs) in high yields without degradation of the polymer backbo

300 ated carbon and furnishes arenes and phenols in high yields without hydrogenation.