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1 c stress was markedly reduced when lon-1 was inactivated.
2 loses its grip on the RNA:DNA hybrid and is inactivated.
3 ion rates, transposons are then more rapidly inactivated.
4 s-proline-dependent Ssu72 CTD phosphatase is inactivated.
5 rature, conditions where trypsin is normally inactivated.
6 ranscriptional regulator oxyR is genetically inactivated.
7 d when p97's ATPase activity is inhibited or inactivated.
8 hough some underlying conductances should be inactivated.
9 This effect is reversed when RAP1 is inactivated.
10 that mediate fusion, become proteolytically inactivated.
11 Autoantibodies against leucine-rich glioma inactivated 1 (LGI1) are found in patients with limbic e
12 common in patients with leucine-rich, glioma-inactivated 1 (LGI1)-IgG associated and contactin-associ
13 (pCSF(NMDAR), n = 7) or Leucine-rich-glioma-inactivated-1-Ab (pCSF(LGI1), n = 6) associated AE suppr
14 human eosinophils and were internalized and inactivated (95% in <= 2 hours) as reflected by a reduce
17 ination with either MF59- or AS03-adjuvanted inactivated A(H7N9) vaccines elicited robust, cross-reac
18 e a set of affinity optimized, enzymatically inactivated ACE2 variants that potently block SARS-CoV-2
20 four subjects suggest that vaccination with inactivated adjuvanted vaccine induce NA-reactive respon
22 polarized, T-type VGCCs and A-type VGKCs are inactivated and CF-EPSPs activate P/Q-type VGCCs, high-v
23 he DNA-binding species with the binding site inactivated and eGFP as a calibration standard among lab
24 e et al., 2013, in which the hippocampus was inactivated and grid cells were recorded in the rat MEC.
26 in the attention network when one of them is inactivated and reveals whether they might have a causal
28 al strains have different methyltransferases inactivated and thus different methylation patterns.
30 n the vaccine without the need for purified, inactivated, and calibrated virus reference antigens.
31 ng chromosomal fusion, the neocentromere was inactivated, and the native centromere of the fused chro
32 recombinant antigens (RCA) and a whole-cell inactivated antigen vaccine (WCA), in conferring protect
36 athological sites when mobilized by distinct inactivated bacterial-based stimuli administered subcuta
38 zed L. braziliensis transfectants were photo-inactivated before (Strategy #1) or after (Strategy #2)
40 ify genes which are up or down regulated, or inactivated, between multiple conditions, producing a fi
41 e develop mice in which we have specifically inactivated both insulin receptors (IRs) and IGF-1 recep
44 ro1), and protein disulfide-isomerase can be inactivated by a feedback inhibition mechanism involving
45 ant plants, in which OsSBEIIb was completely inactivated by abolishing the catalytic center and C-ter
46 oading with L. braziliensis photodynamically inactivated by both strategies, including CD86 expressio
48 rahydrocannabinol (THC), are metabolized and inactivated by cytochrome P450 enzymes primarily within
50 ere randomly assigned to receive VZV vaccine inactivated by gamma irradiation (n=2637) or placebo (n=
51 d (1:1) to receive four doses of VZV vaccine inactivated by gamma irradiation or placebo approximatel
53 alphaviruses, CHIKV replicase was completely inactivated by mutations preventing palmitoylation of ns
58 synthase (GSa) - respectively activated and inactivated by phosphorylation - and their Ca(2+)-depend
59 nd active at 25 degrees C, but is completely inactivated by protein unfolding at higher temperatures.
60 overexpression of constitutively active Rabs inactivated by RN-tre failed to alter NMII RLC localizat
62 ransgenic DNA is recognized and then quickly inactivated by the assembly of a repressive chromatin st
64 mutation (p53HRmut) and wildtype p53 (p53WT) inactivated by the human papillomavirus 16 (HPV16) E6 on
65 ir potential to be rapidly hydrolyzed (i.e., inactivated) by extracellular peptidases during biologic
66 mpared the protective efficacies of formalin-inactivated C. burnetii Nine Mile phase I (PIV) and phas
67 luated the protective efficacy of a formalin-inactivated C. burnetii Nine Mile phase I vaccine (PIV)
69 Inhibiting the alpha5-GABA(A)R in mice with inactivated CA1 VIP input could still improve spatial le
70 chnologies, we show that pigs with all PERVs inactivated can also be genetically engineered to elimin
72 rx/TrxR restored the activity of polysulfide-inactivated caspase-3 in vitro, and TrxR inhibition pote
74 he 2017-2018 influenza season, quadrivalent, inactivated cell-derived influenza vaccine (ccIIV4) vacc
76 several structures, including multiple open-inactivated conformations, further indication of a highl
77 of the Bay K8644 enantiomers exhibit similar inactivated conformations, suggesting that (S)-(-)-Bay K
81 mothers exposed to D pteronyssinus, protease-inactivated D pteronyssinus, or to PBS during lactation.
82 with PRSS1WT mice, as well as enzymatically inactivated Dead-PRSS1R122H mice, we unraveled that incr
83 gly, however, we found that vaccination with inactivated DENV enhanced ZIKV infection, mainly in the
84 ch in ISCs; its de-repression, when Notch is inactivated, drives progenitor cells to differentiate al
85 e chitin-active variants became more rapidly inactivated during catalysis than a natural chitin-activ
87 Here, we report that glycolysis, which is inactivated during RLR activation, serves as a barrier t
89 repressor, like the lambda CI repressor, is inactivated during the SOS response to DNA damage, and t
91 levels are decreased in cells where TP53 is inactivated, either by HPV16 E6, by expression of a domi
93 eal-time mobility behaviors of activated and inactivated endogenous conformers during agonist treatme
100 itrogen from histidine in vitro, and strains inactivated for hutH are severely attenuated in a murine
106 ted in an in vitro infection model with heat-inactivated Gram-positive (Staphylococcus aureus) and Gr
108 low-dose IL-15, alone or in combination with inactivated H3N2 virus; the associated NK cell response
109 tiple HCAs, hepatocyte nuclear factor 1alpha-inactivated HCAs showed a higher rate of progression com
110 disease, with hepatic nuclear factor 1alpha-inactivated hepatocellular adenomas being the most commo
111 eroxide and hydrogen peroxide production and inactivated HIF (hypoxia-inducible factor)-1alpha, which
120 ntroducing ester functionalities that can be inactivated in blood as well as by the liver (dual-soft)
121 SNF chromatin remodeling gene, is frequently inactivated in cancers and is not directly druggable.
122 uppressor of cytokine signaling-1 (SOCS1) is inactivated in hematopoietic and solid cancers by promot
123 ymes can suppress tumors, but they are often inactivated in human cancers overexpressing inhibitory p
124 ndent tumour suppressors that are frequently inactivated in human cancers, and FOXO3 is the second mo
126 n of an actionable target downstream of RB1, inactivated in SCLC and other advanced tumors, could hav
127 f area 25, but not area 32, areas which when inactivated independently reduced and had no effect on a
128 Furthermore, immunization of Tc caprine with inactivated influenza A (H7N9) viruses followed by H7N9
129 ion rates are not well understood for 2-dose inactivated influenza vaccination (IIV) schedules in aut
130 ticipants received a standard-dose trivalent inactivated influenza vaccination (IIV3) at enrollment,
131 Available evidence indicates that seasonal inactivated influenza vaccination during pregnancy prote
133 ecombinant HA vaccine (rHA) and cell-derived inactivated influenza vaccine (IIV) to egg-derived IIVs
134 uter-based system to intramuscular trivalent inactivated influenza vaccine (IIV3) or a control of ina
136 posed to different combinations of trivalent inactivated influenza vaccine (TIV with or without adjuv
137 , comparator-controlled (trivalent high-dose inactivated influenza vaccine [IIV3-HD], or quadrivalent
138 ter-generated randomisation list, to receive inactivated influenza vaccine containing 15 mug of each
139 identified persons who were vaccinated with inactivated influenza vaccine from 1 September 2010 to 3
141 and safety of different dosing schedules of inactivated influenza vaccine in pregnant women living w
143 Our results suggest that effectiveness of inactivated influenza vaccine wanes during the course of
144 etected in patients on ICIs who received the inactivated influenza vaccine within ~ approximately 2 m
145 4 weeks after immunization with the seasonal inactivated influenza vaccine, but numbers returned to n
147 neutralizing antibody responses elicited by inactivated influenza vaccines (IIV), but neutralizing a
148 016 through 2017-2018, injectable, trivalent inactivated influenza vaccines (IIV3) and a nasal spray,
149 ter IV A(H3N2)v vaccine and several seasonal inactivated influenza vaccines (IIVs) in adults, elderly
150 cent influenza seasons, the effectiveness of inactivated influenza vaccines against circulating A(H3N
151 cells, which are not induced by traditional inactivated influenza vaccines and may provide protectio
153 HD-MAPs were coated with a monovalent, split inactivated influenza virus vaccine containing A/Singapo
154 regarding the utility of currently licensed inactivated influenza virus vaccines and novel protein-b
156 lls were stimulated with soluble antigens or inactivated intact Bp and the presence or absence of blo
157 ry dermal endothelial cells with live and UV-inactivated KSHV demonstrated that viral gene expression
158 Cytosolic Par-1 bound, phosphorylated, and inactivated KSR scaffolding proteins ultimately inhibite
159 sults provide evidence that photodynamically inactivated L. braziliensis are susceptible to the degra
161 ions (VAH), similar to those in humans given inactivated measles or respiratory syncytial virus vacci
163 s (43 degrees C for 25 min), germ cells with inactivated Mgat4d were markedly more sensitive to the e
164 n of 25 amino acids (aa) from the C terminus inactivated MGAT4D-L, but deletion of 20 aa did not.
166 okines; however, apoptotic and metabolically inactivated MSCs have more recently been shown to posses
167 les in synaptic transmission, we genetically inactivated mTORC1 or mTORC2 in cultured mouse glutamate
169 r findings indicated that aBL preferentially inactivated N. gonorrhoeae, including antibiotic-resista
170 plasma potassium by oral gavage of potassium inactivated NCC within 1 hour in wild-type mice, but had
172 ly B (NOMV-FHbp), NOMV with FHbp genetically inactivated (NOMV-KO), and/or a control rFHbp vaccine ag
173 cells to lose their identity, we genetically inactivated Notch1 and Notch2, inactivated the Notch sig
175 mouse, in which the insulin receptor (IR) is inactivated only in skin, with no other metabolic conseq
176 in record time, allowing the development of inactivated or attenuated viral vaccines along with subu
177 pathological processes that were activated, inactivated, or unchanged vs. RVD with no intervention.
180 y a source of visual salience, we reversibly inactivated parietal cortex and simultaneously recorded
181 e in this system, here, we pharmacologically inactivated parts of vlPFC and simultaneously measured I
185 ity in competition studies using homologous (inactivated Pitman Moore rabies virus) and heterologous
186 l coverage through routine immunization with inactivated polio vaccine (IPV), to ensure type 2 immuni
188 booster dose of tetanus-diphtheria-pertussis inactivated polio vaccine (Tdap) 3 months later; BCG and
189 dministering daily intradermal injections of inactivated polio vaccine according to six different del
190 vaccinate children-who had only received the inactivated polio vaccine-with the oral polio vaccine (O
191 phtheria-tetanus toxoids-acellular pertussis-inactivated poliomyelitis-Haemophilus influenza type b-h
193 Intradermal administration of fractional inactivated poliovirus vaccine (fIPV) is a dose-sparing
194 ted influenza vaccine (IIV3) or a control of inactivated poliovirus vaccine (IPV) in the beginning of
195 g OPV in the phase 4 study and either OPV or inactivated poliovirus vaccine (IPV) in the novel OPV2 p
198 een in CA1 via increased levels of oxidized, inactivated potassium channel Kv2.1, which undergoes dis
199 , we observed that immunization of mice with inactivated poxvirus primes a virtually undetectable CD4
202 that additional distraction reactions, where inactivated proteases become competitive inhibitors to r
203 ed their potency in vivo in BALB/c mice with inactivated quadrivalent influenza vaccine (QIV) and tes
204 investigated cT(FH) responses to the 2017-18 inactivated quadrivalent influenza vaccine (QIV) in men
206 ssing technology to heat-stabilize FiloRab1 (inactivated rabies-based Ebola vaccine), a candidate Ebo
209 ages of lager-brewing yeasts, have inherited inactivated S. cerevisiae alleles of critical phenolic o
210 hen simultaneously exposed to an inoculum of inactivated Salmonella Enteritidis and a chronic heat st
212 he present study, simulated sunlight rapidly inactivated SARS-CoV-2 suspended in either simulated sal
213 evaluated using mock test samples containing inactivated SARS-CoV-2 virions, added to in vitro derive
214 adjustment for age and prior LAIV (n = 436), inactivated seasonal vaccine (n = 100), or (H1N1)pdm09 v
216 expression of Snail, Twist, and Notch1; and inactivated several profibrotic signaling molecules in t
217 current study, we produced monoglycosylated inactivated split H1N1 virus vaccine from chicken eggs b
218 3-3 adaptor proteins that hold CaMKK2 in the inactivated state by preventing dephosphorylation of pho
220 of a drug for binding to the open versus the inactivated state of K(v)11.1 can also be inferred from
221 ide Nav1.7 channel blocker that binds to the inactivated state of Nav1.7 channels with high affinity
222 7 inhibitors that preferentially inhibit the inactivated state of the channel, ST-2262 is equipotent
223 which also bind with higher affinity to the inactivated state than the resting state but bind at a s
224 where a small fraction of channels are in an inactivated state under drug-free conditions, inhibition
225 N642H) can adopt a hyper-activated and hyper-inactivated state with resistance to dephosphorylation.
227 nterface drive the channel into an hERG-like inactivated state, thereby obscuring its opening upon de
229 states (with D4S4 in the inner position) and inactivated states (with D4S4 in the outer position).
231 act of sensory evidence, we chemogenetically inactivated the excitatory projections from auditory cor
232 emia cells increased ceramide levels 2-fold, inactivated the key signaling protein extracellular sign
234 e genetically inactivated Notch1 and Notch2, inactivated the Notch signaling target Hes1, or induced
238 ancer progression: most carcinoma cells have inactivated their epithelial antiproliferative response
239 some molecules of their protective catalase inactivated, these tumor cells allow locally surviving c
240 h plays a crucial role in gene silencing, is inactivated through recurrent mutations in core subunits
247 e transcriptional repressor role of SerRS is inactivated under hypoxia through phosphorylation by ata
248 ll number of bacterial genes are known to be inactivated upon IGE integration and reactivated upon ex
249 ain (H1/stalk) following trivalent influenza inactivated vaccine (IIV3) immunization in pregnant wome
250 accine (n = 20), live-attenuated followed by inactivated vaccine (n = 15), twice AS03-adjuvanted inac
251 ated vaccine (n = 15), twice AS03-adjuvanted inactivated vaccine (n = 16) or placebo (n = 5, intranas
252 live-attenuated followed by AS03-adjuvanted inactivated vaccine (n = 20), live-attenuated followed b
253 a single-dose immunization of ZIKV purified inactivated vaccine (ZPIV)(4-7) in a dengue virus (DENV)
254 his vaccine response, we immunized mice with inactivated vaccine and injected Ag-pulsed activated APC
255 ine on day 85; the same regimen but with the inactivated vaccine being adjuvanted with AS03; and an A
257 03-adjuvanted, chimeric H8/1, intramuscular, inactivated vaccine followed by an AS03-adjuvanted, chim
258 on-adjuvanted, chimeric H5/1, intramuscular, inactivated vaccine on day 85; the same regimen but with
259 This suggests that CD4 effectors induced by inactivated vaccine require high levels of cognate Ag re
265 e, through strategies that included seasonal inactivated vaccines, Flumist, and synthetic peptides de
268 to investigate the efficacy and safety of an inactivated varicella zoster virus (VZV) vaccine for her
269 ety and interchangeability of a single dose, inactivated Vero-cell derived, JENVAC(R) to the live att
270 ty, and interchangeability of a single-dose, inactivated, Vero-cell derived, JENVAC to the live-atten
271 Pitman Moore rabies virus) and heterologous (inactivated vesicular stomatitis virus) antigens and acc
272 sponsive enhancer that becomes progressively inactivated via Polycomb-mediated silencing as discs mat
273 ctures of Env trimers on aldrithiol-2 (AT-2)-inactivated virions in ligand-free, antibody-bound and C
274 e culture infective dose (TCID(50))/ml using inactivated virus and 25 copies/ml (c/ml) using syntheti
275 intranasal LTA1 enhanced immune responses to inactivated virus antigen and subsequent protection agai
280 wed similar limits of detection (LODs) using inactivated virus, with 100% detection, ranging from 500
282 inic for gene therapy and immunotherapy, and inactivated viruses or virus-like particles have long be
285 l patients who received at least one dose of inactivated VZV vaccine or placebo and had follow-up dat
287 s (CMV)-cre strain, Wasf3 constitutively was inactivated, which led to viable mice with no visible mo
293 est parenteral administration of adjuvanted, inactivated whole-cell vaccines for O157 can induce O157
296 LRP5-deficiency in osterix-expressing cells inactivated Wnt signaling in the nucleus pulposus by 95%
297 Wwp2 and mice in which the Wwp2 E3 enzyme is inactivated (Wwp2-C838A) exhibit aggravated spontaneous
298 ect of the pre-harvest treatment by specific inactivated yeasts (YE) on the qualitative parameters an
299 of an aluminum hydroxide adjuvanted purified inactivated Zika vaccine (PIZV) against challenge with Z