ライフサイエンスコーパス: individual variation

1 verage genome that provide a source of inter-individual variation.

2 to assess because of large amounts of intra-individual variation.

3 ne expression but also epigenetics and inter-individual variation.

4 ular disease, yet exhibit considerable inter-individual variation.

5 d to the subsequent observation of low inter-individual variation.

6 well as when we looked at generic aspects of individual variation.

7 with a mainly genetic contribution to inter-individual variation.

8 promoters to reveal the full extent of inter-individual variation.

9 hanisms that simultaneously permit and limit individual variation.

10 tal blood fatty acids, with DHA showing more individual variation.

11 can be obtained, overcoming the challenge of individual variation.

12 This approach also reduced individual variation.

13 of the wavelength spectrum, as well as their individual variation.

14 omputational model that can account for such individual variations.

15 Both genes were found to have large inter-individual variations.

16 ain as being responsible for the majority of individual variation across the normal population.

17 PCOs cannot account for individual variation among patients and cannot be consid

18 ze that guidelines cannot always account for individual variation among patients.

19 ze that guidelines cannot always account for individual variation among patients.

20 aniasis guidelines cannot always account for individual variation among patients.

21 iation cannot be ascribed to inter- or intra-individual variations among the observers, and points to

22 ematic framework to dissect inter- and intra-individual variation and build predictive models of post

23 e models in one framework and illustrate how individual variation and correlations in development can

24 to stratify patient care, the complexity of individual variation and covert actions of genetic modif

25 novel biomarkers of disease, characterizing individual variation and mapping the architecture of hig

26 and a more variable one, possibly reflecting individual variation and medication use.

27 ), while the lumenal microbiota showed inter-individual variation and obligate anaerobe enrichment (e

28 equired to distinguish within versus between-individual variation and repeatability of gene expressio

29 We examined within and between individual variation and repeatability of platelet RNA e

30 vity maps display a delicate balance between individual variation and stereotypy, suggesting the exis

31 When fully accounting for individual variation and the full spectrum of neuro-opht

32 n-individual phenotypic plasticity and among-individual variation and to test alternative hypotheses

33 ortant questions around the normal limits of individual variation and whether individuals may be pred

34 uch selfish replication by minimizing within-individual variation and, hence, within-individual selec

35 ire us to better account for habitat-derived individual variation, and to do so for the sexes appropr

36 emotion and stress processing, the bases of individual variation are less well understood.

37 How inter-individual variations are manifested in the functional b

38 In addition, individual variation can exacerbate the effects of demog

39 Substantial individual variation, coupled with high heritability and

40 Gains in VO2 max demonstrate large inter-individual variation even in response to standardized ex

41 We asked whether similar individual variation exists for contextual cues associat

42 to be reasonably attributed to the amount of individual variation expected among con-specifics.

43 nalysis (Sparse mCCA), angle-based joint and individual variation explained (AJIVE) and multi-omics f

44 Joint and individual variation explained (JIVE) is a tool for expl

45 A range of moderating factors relating to individual variation, features of the intragroup and int

46 s, and observed the highest inter- and intra-individual variation for metabolites produced by the col

47 has been reported to show significant inter-individual variation from the effects of seven common su

48 Heterogeneity between countries and intra-individual variation highlight meaningful avenues for fu

49 A pathology was associated with substantial individual variation; however, within this group progran

50 Despite cultural and individual variation, humans are a judgmental bunch.

51 Individual variation in a specific type of mutation, unc

52 The procedure has significant value to study individual variation in acquisition of conditioned respo

53 e found a new metric of condition reflecting individual variation in acquisition, assimilation and/or

54 Trait social anxiety is associated with individual variation in affective responding, even in re

55 our understanding of factors contributing to individual variation in ageing rates and fitness.

56 eared on an ad lib diet exhibited consistent individual variation in aggression and web weight only.

57 venly distributed across the population, and individual variation in altruistic tendencies may be gen

58 Individual variation in anaemia was likely driven by ran

59 We investigated whether the individual variation in antiviral response at birth dete

60 Together these data confirm that individual variation in aspects of ongoing experience ca

61 In two longitudinal cohorts, inter-individual variation in baseline FSA scores was signific

62 However, the role of individual variation in behavior to facilitate the persi

63 The amount of individual variation in behaviour and web structure vari

64 Among-individual variation in behaviour is a widespread phenom

65 Between-individual variation in behavioural phenotype, termed pe

66 spite the recent attention given to studying individual variation in behavioural plasticity, there is

67 erogeneous environment might promote between-individual variation in behavioural plasticity.

68 s have revealed a relationship between inter-individual variation in blood pressure and the single nu

69 nd environmental factors interact to produce individual variation in body mass and accounting for thi

70 r DNA-methylation profiles account for inter-individual variation in body mass index (BMI) and height

71 udy, we present an analysis of the effect of individual variation in body mass on the temporal dynami

72 we show that the models explicitly including individual variation in body mass predict group dynamics

73 Individual variation in both survival and reproduction h

74 to resolve the longitudinal consequences of individual variation in brain development before birth.

75 cilitate subsequent studies to explain inter-individual variation in cardiometabolic disease.

76 udied extensively, but the genetic basis for individual variation in CHC composition is largely unkno

77 bolism and represent mechanistic targets for individual variation in CHC composition.

78 uilding on this finding, we hypothesize that individual variation in childhood brain energy expenditu

79 sual attention significantly associated with individual variation in childhood surgency and behaviora

80 Here, I review recent studies focused on individual variation in chromatin, and outline how epige

81 r CIITA and complement this by mapping inter-individual variation in CIITA expression as a quantitati

82 raits in mammals, but the factors underlying individual variation in circulating T levels are poorly

83 Inter-individual variation in clearance of methotrexate result

84 ness for apoptosis ("priming") might explain individual variation in clinical behavior.

85 In contrast, the NVH predicts that among-individual variation in cognition, physiology or morphol

86 the role that genetic factors might play in individual variation in cognitive abilities in nonhuman

87 ts support a unique role of the right SFG in individual variation in cognitive control.

88 ts and its relationship to cognitive effort, individual variation in cognitive performance, and fatig

89 by pheasants at feeders can be predicted by individual variation in cognitive performances and we su

90 s, but the evolutionary processes that shape individual variation in cognitive traits remain elusive

91 ely-viewed image of a dress elicits striking individual variation in colour perception.

92 us to identify factors associated with inter-individual variation in correlation.

93 icrobial communities may contribute to inter-individual variation in cytokine responses to microbial

94 The between-individual variation in daily physical activity and sede

95 nd immunological hypotheses explaining inter-individual variation in dengue viral load.

96 he two prey types, and exhibit greater among-individual variation in diet and morphology.

97 The common variants explain ~4% of inter-individual variation in disease risk and no more than 13

98 sal strategies have received much attention, individual variation in dispersal decisions and its fitn

99 ce of environmental heterogeneity or between-individual variation in dispersal phenotypes, two condit

100 s and genomic regions characterized by inter-individual variation in DNA hydroxymethylation.

101 amilies, to establish a catalogue of between-individual variation in DNA methylation.

102 c integrity, and evidence suggest that inter-individual variation in DNA repair efficiency may contri

103 This study tested the hypothesis that individual variation in dopamine and corticosteroid phys

104 e [29, 32-35] and whose genetic ancestry has individual variation in European and continental African

105 etime reproductive success but such realized individual variation in fitness components need not refl

106 The role of habitat use in generating individual variation in fitness has rarely been examined

107 There is accumulating evidence that individual variation in foraging behaviour is shaped by

108 dual life histories; and revealed consistent individual variation in foraging patterns, refuge use an

109 Quantitatively linking individual variation in functional traits to demography

110 We found extensive individual variation in gene expression and cellular res

111 Inter-individual variation in gene expression has been shown t

112 However, we also provide evidence that inter-individual variation in gene regulation can be genetical

113 Individual variation in germline and expressed B-cell im

114 a large neuroimaging dataset, we found that individual variation in global signal topography recapit

115 basis of type 2 diabetes (T2D) and the inter-individual variation in glycemic traits, including level

116 orts as well as the existence of substantial individual variation in growth trajectories after accoun

117 ata from fecal samples to characterize inter-individual variation in gut bacterial species.

118 Additionally, our data reveal more inter-individual variation in gut microbiome functional potent

119 ut provide new information for understanding individual variation in hemostasis pathways.

120 It has been shown that inter-individual variation in host response to porcine reprodu

121 in peak parasite load was due to unobserved individual variation in host responses to clear infected

122 Much of this inter-individual variation in human sociality remains unexplai

123 enes and genetic mechanisms underlying inter-individual variation in human traits, as well as support

124 To explore drivers of dose-dependence and individual variation in infection outcomes, we devised a

125 s, were used to examine the contributions of individual variation in infectiousness and clustered con

126 ketamine-induced effects, although the high individual variation in ketamine response requires furth

127 be crucial to determine the extent to which individual variation in key functional attributes is gen

128 Furthermore, we found that individual variation in levels of aversive pruning was a

129 Quantifying among-individual variation in life-history strategies, and ass

130 osophila melanogaster displays individual-to-individual variation in locomotor behaviors.

131 Collectively, our research illustrates that individual variation in mesopredator habitat use can sca

132 We examined individual variation in metabolic flexibility in respons

133 as the main driver of both intra- and inter-individual variation in metabolism of dietary bioactive

134 A recent article examines the extent of individual variation in microbial identities and how thi

135 nstrated clear age group differences, albeit individual variation in microbiomes between animals with

136 s of reinforcement learning and suggest that individual variation in midbrain D3 receptors influences

137 t and/or indirect mechanisms, but imply that individual variation in migratory strategy and variation

138 However, natural selection acting on wide individual variation in molt phenology might enable evol

139 atly increased by identifying and exploiting individual variation in motivations.

140 We introduce a framework for investigating individual variation in movement-defined resource select

141 Inter-individual variation in MRS-measured GABA levels have be

142 Notably, the inter-individual variation in mutation rate and spectra are lo

143 However, there was substantial individual variation in natural history.

144 Little is known about the nature of this individual variation in natural populations, or which co

145 chical techniques have been used to estimate individual variation in parameters over a population of

146 Women in the study had larger within-individual variation in partner ages compared to men.

147 articularly in populations with large within-individual variation in partner ages.

148 Inter-individual variation in patterns of DNA methylation at b

149 Individual variation in peak absorbance is large and ran

150 Individual variation in peak reproductive effort thus ha

151 Despite significant inter-individual variation in pharmacokinetic parameters, conc

152 transform our understanding of links between individual variation in physiology and behaviour and elu

153 ement of emotional appraisal circuits drives individual variation in placebo analgesia, rather than e

154 The ecological consequences of inter-individual variation in plant volatile emissions remain

155 e molecular mechanisms responsible for inter-individual variation in plasma protein levels are poorly

156 Here, we examine factors responsible for individual variation in PPC frequency within a single wi

157 ealing with both information uncertainty and individual variation in preferences.

158 However, the neural bases underlying individual variation in proactive control of impulsive r

159 ulations also differed in the level of among-individual variation in reaction norm intercept, but we

160 intercept, but we found no evidence of among-individual variation in reaction norm slope.

161 , but little is known of the factors causing individual variation in reproductive ageing rates.

162 experimentally that natal environment shapes individual variation in reproductive and actuarial agein

163 abilities with advancing age, indicative of individual variation in resilience to pathology.

164 Individual variation in response and duration of anti-va

165 This study evaluated the hypothesis that individual variation in response to estrogen levels cont

166 derstanding of how these contribute to inter-individual variation in response to infection.

167 Our results showed substantial inter-individual variation in responses, but females did not r

168 The results suggest that individual variation in resting-state brain dynamics off

169 Considerable between-individual variation in retinal ganglion cell (RGC) dens

170 gene to elucidate the complexity of between-individual variation in retinal phenotype.

171 Owing to large inter-individual variation in rhythm timing and the magnitude

172 Moreover, we observed significant among-individual variation in seasonal changes in reproduction

173 Individual variation in self-reported mood awareness was

174 Offspring sex ratio may help explain among-individual variation in senescence rates in other specie

175 The data reveal individual variation in sensitivity to reproduction and

176 Preference formation is influenced by inter-individual variation in sensitivity to rewarding and ave

177 ich deviation from this target could predict individual variation in severity of delusions.

178 Underlying mechanisms of individual variation in severity of influenza infection

179 sexually dimorphic traits (e.g., ornaments), individual variation in sexually selected traits often e

180 into the biological mechanisms that underlie individual variation in shift work tolerance.

181 e a principal component analysis to describe individual variation in six feeding parameters and exami

182 es insights into the genetic basis for inter-individual variation in sleep duration implicating multi

183 Individual variation in social behavior seems ubiquitous

184 Consideration of consistent individual variation in space-use will facilitate mechan

185 We hypothesised that inter-individual variation in Sry mRNA-abundance would result

186 ocial status in primates might be related to individual variation in subcortical brain regions implic

187 ternatives, and vmPFC effect sizes predicted individual variation in suboptimal decision-making in th

188 Inter-individual variation in survival stems from variation in

189 ly conserved candidate genes associated with individual variation in susceptibility to lead exposure.

190 However, identifying genes that give rise to individual variation in susceptibility to lead toxicity

191 Our results may also help to explain individual variation in susceptibility to opioid medicat

192 preclinical approach for studying sources of individual variation in susceptibility to relapse due to

193 Individual variation in tendency to be along the road ca

194 was predicted to be most sensitive to inter-individual variation in the activity of enzymes which, e

195 Individual variation in the addiction liability of amphe

196 aken together, these experiments demonstrate individual variation in the attribution of incentive sal

197 ating telomere dynamics may help us quantify individual variation in the costs experienced from socia

198 Individual variation in the data suggested differences i

199 of multiple neuropsychiatric disorders, and individual variation in the degree of inherent impulsivi

200 rain dynamics offer a neural explanation for individual variation in the error dynamics of human beha

201 andidate models are themselves compared, and individual variation in the expressed model estimated, a

202 There is considerable individual variation in the extent to which reward cues

203 Increased inter-individual variation in the human microbiome may be asso

204 study designs are starting to explain inter-individual variation in the immune response.

205 reveals for the first time substantial inter-individual variation in the NCO:CO ratio.

206 G6PD heterozygous females, because of individual variation in the pattern of X-chromosome inac

207 Individual variation in the presence of pain, rather tha

208 There is, however, considerable individual variation in the propensity to attribute ince

209 conflict-based relapse model to ask whether individual variation in the propensity to attribute ince

210 Here we capture individual variation in the propensity to attribute moti

211 uld be chosen conservatively or adjusted for individual variation in the rate at which washout occurs

212 relative contribution of genetic factors to individual variation in the shape of seven bilateral sub

213 Despite individual variation in the shape of V1, the relationshi

214 to retinotopy generally, is the substantial individual variation in the size, volumetric position, a

215 Individual variation in the strength of this functional

216 Given individual variation in the susceptibility to NODAT, we

217 k coupling to the visual system may underpin individual variation in the tendency for our attention t

218 f this functional mode predicted significant individual variation in the types of thoughts that indiv

219 Consequently, individual variation in the underlying neurocognitive ar

220 emphasize the need for incorporating between-individual variation in theoretical and empirical studie

221 However, even in adolescence considerable individual variation in these behaviors exists, which ma

222 Individual variation in these mechanisms may stem from v

223 However, the inter-individual variation in this risk is poorly understood.

224 and unique environmental factors to between-individual variation in traits.

225 This individual-to-individual variation in viral escape mutations is not pr

226 patterns of clinical manifestation and inter-individual variation in viral load dynamics.

227 In doing so, we quantified among-individual variation in vulnerability to cause-specific

228 Finally, we asked whether individual variation in wheel use within a group of mice

229 Individual variation in WM has been associated with mult

230 ese fluctuations may be a key determinant of individual variations in ability(6,7).

231 ies will be required to define whether inter-individual variations in ABO(H) expression on platelets

232 By relating individual variations in antibody response to coronaviru

233 Individual variations in aversive pruning levels related

234 tions in these connections may be related to individual variations in behaviour and cognition.

235 ysis of the data obtained demonstrated inter-individual variations in both in vitro and in vivo bacte

236 Individual variations in cellular drug uptake, metabolis

237 approximately 2% Gly(241) alleles) points to individual variations in complex formation.

238 techniques to investigate the main source of individual variations in contrast sensitivity.

239 tioned reinforcement from positive cues, and individual variations in decision strategy and the cogni

240 classification and greater understanding of individual variations in disease pathology could drive t

241 DMN genes show significant associations with individual variations in DMN functional activity, intell

242 e robust to both noise in light and to inter-individual variations in endogenous circadian period tha

243 and has quantitative implications for inter-individual variations in glucose/insulin homeostasis.

244 iations (p<0.05) between gene SNPs and inter-individual variations in IFN-alpha, IL-12p40, IL-1beta,

245 model-based analysis approach to account for individual variations in learning, we found that the oxy

246 ar viral replication and cancer development, individual variations in mRNA editing and the genetic tr

247 ed the degree of CHT mobilization as well as individual variations in performance on the sustained at

248 proaches may be adversely affected by common individual variations in skull anatomy.

249 I hypothesize that individual variations in society result in higher energe

250 Individual variations in the brain's capacity to synthes

251 task-evoked activity, it is unclear whether individual variations in the connectivity pattern of a b

252 There are remarkable population and individual variations in the formation of TMSe, which co

253 It concludes by outlining how individual variations in the inflammatory response could

254 Individual variations in the innate immune response to r

255 iomics," which seeks to understand how inter-individual variations in the microbiome shape drug effic

256 ility in trait anxiety is causally linked to individual variations in the physiological constitution

257 nnections (correlations in time series), and individual variations in these connections may be relate

258 malism-hypergraph cardinality-we investigate individual variations in two separate, complementary dat

259 nd empirical investigations of the bases for individual-variation in political ideology.

260 In different ASD individuals, variation in how and when these pleiotropic

261 onal point between a microscopic scale where individual variation is prominent and the macroscopic le

262 Compelling intuitive arguments suggest that individual variation may provide a previously unrecognis

263 y of the visual system [4,7,8] suggests that individual variations may be found in even more basic vi

264 Despite significant individual variation, not addressed by Jennings, S. roes

265 are a major contributing factor to the inter-individual variation observed in response to human immun

266 However, most individual variation occurs outside of genes and, indeed

267 wever, little is known about repertoires and individual variation of anti-carbohydrate antibodies in

268 less than 20% inhibition of BChE) because of individual variation of BChE values but also avoids the

269 ,700 lipids) accounted for >60% of the inter-individual variation of BMI, WC, and leptin in our popul

270 Little is known about the inter-individual variation of cytokine responses to different

271 enabling high-throughput assessment of inter-individual variation of growth.

272 disease ecology is to understand the role of individual variation of infection load on disease transm

273 We have characterized inter- and intra-individual variation of microbial communities of 107 ind

274 Accordingly, we explored inter-individual variations of functional connectivity dynamic

275 strates of individuality, reflected in inter-individual variations of large-scale functional connecti

276 Individual variations of white matter (WM) tracts are kn

277 ants into mice can further define effects of individual variation on normative development, how they

278 ch to understanding the impact of pre-morbid individual variation on post-lesion outcomes that could

279 There was a substantial within-individual variation on the accuracy of reporting.

280 Here, we test the effect of individual variation on the long-term trajectories of bi

281 9 and miR-146 and has implications for inter-individual variations on cardiometabolic traits.

282 cated CpG sites accounted for up to 6% inter-individual variation (R2) of age-adjusted and sex-adjust

283 ailed annotation provides interpretation for individual variation responsible for normal and disease

284 ical parameters, which we attribute to intra-individual variation (SD = 1.6-8.1 mM).

285 Plots of individual variation (SD) against mean error allowed the

286 the same time higher and subject to a larger individual variation than previously assumed.

287 memories than others, given the substantial individual variation that exists in retrieval ability an

288 t-symptom onset (range 1-40), with extensive individual variation that is not significantly associate

289 use appropriate procedures remain subject to individual variation that statistical methods cannot cor

290 Individual variations thus define a specific structural

291 contributions of developmental programs and individual variation to behavior by monitoring single Ca

292 ce understanding of adolescent potential and individual variation to further generate developmentally

293 hese results emphasize the need to integrate individual variation to generate new insights when model

294 a h 2 (rho(s) = 0.60, P < 0.0001), but large individual variation was found.

295 hin any one tissue, we found that some inter-individual variation was reflected across brain and bloo

296 Nevertheless, individual variation was substantial, and appears to off

297 Using a pooled-sampling method to overcome individual variation, we monitored colony-level molecula

298 mained very low compared to documented inter-individual variation, we suggest that male koalas would

299 Here, we tested the importance of inter-individual variation with respect to the physiology of c

300 Although this can vary widely between individuals, variation within an individual and the asso