ライフサイエンスコーパス: indole-3-carbinol

1 ) and citrus honey (caffeine, 2-oxindole and indole-3-carbinol).

2 ry protein (FLIP) were all down-regulated by indole-3-carbinol.

3 mpounds ascorbigen (13.0 mumol/100 g FW) and indole-3-carbinol (4.52 mumol/100g FW) with their higher

4 l diet experiments show that the reaction of indole-3-carbinol, a breakdown product of indol-3-ylmeth

5 Based on the structure of indole-3-carbinol, a chemopreventive phytochemical, we d

6 We identified indole-3-carbinol, a compound found in cruciferous veget

7 ethane (DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of c

8 ins, further supporting the possibility that indole-3-carbinol acts as an auxin antagonist.

9 nts showed that oviposition was increased by indole-3-carbinol and decreased by indole-3-acetonitrile

10 A direct interaction between indole-3-carbinol and the auxin perception machinery was

11 toxin, quercetin, flavone, chlorogenic acid, indole-3-carbinol, and rutin) and three insecticides (di

12 S breakdown products (indole-3-acetonitrile, indole-3-carbinol, ascorbigen and 3,3'-diindolylmethane

13 Indole-3-carbinol, found in Brassica species vegetables

14 production is induced by herbivory, such as indole-3-carbinol, function not only to repel herbivores

15 The glucosinolate breakdown product indole-3-carbinol functions in cruciferous vegetables as

16 Among them, sulforaphane and indole-3-carbinol have attracted a lot of attention, sin

17 Indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM)

18 Current chemical and biological interest in indole-3-carbinol (I3C) and its metabolites has resulted

19 al digestion for 3,3-diindolylmethane (DIM), indole-3-carbinol (I3C) and sulforaphane (SFN).

20 ic MDA-MB-231 human breast cancer cells with indole-3-carbinol (I3C) directly inhibited the extracell

21 The indole-3-carbinol (I3C) metabolite 3,3'-diindolylmethane

22 Indole-3-carbinol (I3C), a component of Brassica vegetab

23 Indole-3-carbinol (I3C), a compound naturally occurring

24 We tested the chemopreventive efficacy of indole-3-carbinol (I3C), a constituent of Brassica veget

25 Indole-3-carbinol (I3C), a dietary compound found in cru

26 We investigated the efficacy of indole-3-carbinol (I3C), a dietary supplement, and AHR p

27 The effect of indole-3-carbinol (I3C), a major indolic metabolite in c

28 Dietary indole-3-carbinol (I3C), a natural compound present in v

29 Indole-3-carbinol (I3C), a naturally occurring component

30 Indole-3-carbinol (I3C), a naturally occurring component

31 established the cellular mechanism by which indole-3-carbinol (I3C), a promising anticancer phytoche

32 We hypothesized that the phytochemical, indole-3-carbinol (I3C), and some of its acid-condensati

33 The phytochemical indole-3-carbinol (I3C), found in cruciferous vegetables

34 ked whether the antiestrogenic phytochemical indole-3-carbinol (I3C), found in cruciferous vegetables

35 The naturally occurring chemical indole-3-carbinol (I3C), found in vegetables of the Bras

36 vide several classes of compounds, including Indole-3-carbinol (I3C), may have chemopreventive activi

37 tables provides phytochemicals, particularly indole-3-carbinol (I3C), which may be responsible for th

38 The Tg is driven by the indole-3-carbinol (I3C)-inducible rat cytochrome P450 1A

39 iet supplemented with the dietary AhR ligand indole-3-carbinol (I3C).

40 (Ahr) and treatment with the AHR pro-agonist indole-3-carbinol (I3C).

41 s (a) the efficacy of sulforaphane (SFN) and indole-3-carbinol (I3C)/3,3'-diindolylmethane (DIM) on b

42 e tested the ability of dietary AhR ligands (indole-3-carbinol [I3C] and 3,3'-diindolylmethane [DIM])

43 multaneous determination of sulforaphane and indole-3-carbinol in broccoli using UPLC-HRMS/MS is desc

44 ietary supplementation of the AHR pro-ligand indole-3-carbinol in newborn mice promotes resistance to

45 w that OSU-A9 was 100 times more potent than indole-3-carbinol in suppressing the viability of Hep3B,

46 ients that inhibit carcinogenesis, including indole-3-carbinol, indole-3-carboxaldehyde, ferulic acid

47 iety of indole-containing chemicals, such as indole-3-carbinol, indolo[3, 2-b]carbazole, and UV photo

48 c strain, administration of low-dose dietary indole-3-carbinol induces moderate hypertension.

49 Overall, our results indicated that indole-3-carbinol inhibits NF-kappaB and NF-kappaB-regul

50 actor-kappaB (NF-kappaB), we postulated that indole-3-carbinol must mediate its activity through NF-k

51 The tryptophan derivative indole-3-carbinol, or tryptophan-metabolizing Lactobacil

52 ased protein interaction studies showed that indole-3-carbinol perturbs the auxin-dependent interacti

53 Here we examined the hypothesis that indole-3-carbinol plays a role in influencing plant grow

54 We show that indole-3-carbinol rapidly and reversibly inhibits root e

55 y responses that are induced in the plant by indole-3-carbinol remain relatively uninvestigated.

56 ely, re-addition of the plant-derived ligand indole-3-carbinol rescued the barrier deficiency even in

57 n machinery was suggested, as application of indole-3-carbinol rescues auxin-induced root phenotypes.

58 lforaphane and 0.997, 0.42mg/L, 1.29mg/L for indole-3-carbinol, respectively.

59 However, during storage indole-3-carbinol slowly degraded to 0.68 mumol/100 g FW

60 Indole-3-carbinol suppressed constitutive NF-kappaB acti

61 We demonstrated that indole-3-carbinol suppressed constitutive NF-kappaB acti

62 may give rise to degradation products (e.g., indole-3-carbinol) that can enhance tumorigenesis.

63 red by addition of the natural phytochemical indole-3-carbinol to the purified diet.

64 The content of sulforaphane and indole-3-carbinol varied between 72+/-9-304+/-2mg and 77

65 Indole-3-carbinol was an exceptionally potent AHR agonis