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1 ] cycloaddition/N-alkylation cascade to form indolizidines.
2  for a one-pot, three-component synthesis of indolizidines.
3 trogen-heterocycles such as pyrrolidines and indolizidines.
4 routes for the synthesis of polyhydroxylated indolizidines.
5 for the formation of some quinolizidines and indolizidines.
6 lity is demonstrated by a rapid synthesis of indolizidine 167B.
7                   The total synthesis of (-)-indolizidine 195B via a general route, which could poten
8  several sites contained a 5,8-disubstituted indolizidine (205A or 235B), representing another class
9 y chiral GC comparison with the exception of indolizidine 209B (I) for which a natural 209B could no
10 was demonstrated by a total synthesis of (-)-indolizidine 209B.
11 ific route to three (+/-)-5, 8-disubstituted indolizidines, (209B (I), 209I (II), 223J (III)) and two
12  four natural and one non-natural alkaloids: indolizidines (+/-)-209I and (+/-)-8-epi-219F in the rac
13 eld was elaborated into indolizidine 5,8-epi-indolizidine 223A via a five-step reaction sequence in 3
14 nal synthetic plans for the natural product, indolizidine 223A, the new stereoselective cyclization s
15  concise enantioselective total synthesis of indolizidine (-)-223A, a 5,6,8-trisubstituted alkaloid i
16 strated here with the total syntheses of (-)-indolizidine 223AB (1) and alkaloid (-)-205B (2).
17 ddition of pyrrolidino enedione 19 to afford indolizidine 24 as the major product and cyclization/lac
18 ries, and enantiocontrolled syntheses of (-)-indolizidine 251N, (-)-quinolizidine 251AA, and (-)-dehy
19 enated dihydroxypyrrolizidines 20 and 27 and indolizidine 28, respectively, by reductive cleavage of
20 dt reaction, producing the known benzo-fused indolizidine 49, which had been transformed by Ito et al
21 ol obtained in 32% yield was elaborated into indolizidine 5,8-epi-indolizidine 223A via a five-step r
22  the key cyclization yielded, in four steps, indolizidine 6,8-epi-223 in 14% yield.
23                                              Indolizidines (-)-8-epi-swainsonine triacetate and (+)-1
24                                              Indolizidine alkaloid 223A was isolated from a skin extr
25                            Demissidine is an indolizidine alkaloid isolated from several potato speci
26 his methodology is to synthesize benzo-fused indolizidine alkaloid mimics.
27        (-)-Swainsonine is a polyhydroxylated indolizidine alkaloid with potent inhibitory activity ag
28 c synthesis of an unnatural polyhydroxylated indolizidine alkaloid, opening doors to the biosynthesis
29 o the synthesis of many natural hydroxylated indolizidine alkaloids as demonstrated in the formal syn
30                        Natural and unnatural indolizidine alkaloids can be synthesized from simple un
31                                              Indolizidine alkaloids have been the target of chemical
32  e.g. its precursor role in carnitine and in indolizidine alkaloids of physiological interest.
33                                              indolizidine alkaloids of unusual biosynthetic origin ha
34 h could potentially be used to prepare other indolizidine alkaloids such as (-)-gephyrotoxin 223AB an
35 ide migration in the biosynthetic pathway of indolizidine alkaloids.
36  by examining the reaction of a dideuterated indolizidine, alpha,beta-unsaturated N-acyliminium ion p
37 ations for the synthesis of highly alkylated indolizidine and other related alkaloids.
38           A new approach to the synthesis of indolizidine and pyrrolizidine skeletons is reported.
39 idinones and alkynes was developed to access indolizidine and quinolizidine alkaloids.
40 s of allyl and 3-substituted allylsilanes to indolizidine and quinolizidine alpha,beta-unsaturated N-
41 as been developed as an efficient entry into indolizidine and quinolizidine frameworks.
42 pot approach toward the synthesis of various indolizidine and quinolizidine ring systems.
43        A direct approach to the synthesis of indolizidine and quinolizidine scaffolds of iminosugars
44 enyl isocyanates leading to the formation of indolizidine and quinolizidine scaffolds.
45 ive general strategy for the construction of indolizidine and related alkaloids, illustrated here wit
46 etic strategy gives access to functionalized indolizidines and quinolizidines in one operation from r
47      A convergent synthesis of stereodefined indolizidines and quinolizidines through chemoselective
48  preparation of the azabicyclic cores of the indolizidines and quinolizidines using a one-pot cascade
49       We report the synthesis of substituted indolizidines and quinolizidines using the modified Juli
50 itrogen 10 atom at the bridgehead, including indolizidines and quinolizidines, can be prepared in fou
51 oor or electron-rich dipolarophiles yielding indolizidines and related 1-aza[m.3.0]bicycloalkane syst
52 is of highly functionalized pyrrolidines and indolizidines and the reluctance of certain kinds of all
53 ep biocatalytic route to high-value, complex indolizidine, and quinolizidine alkaloids, which relies
54 provides immediate access to arylpiperidine, indolizidine, and quinolizidine scaffolds from the corre
55 the formation of substituted quinolizidines, indolizidines, and pyrrolizidines.
56                                              Indolizidines are bioactive heterocyclic compounds of gr
57  which PTXs, alloPTXs, and 5,8-disubstituted indolizidines are derived.
58 hat functionalized tetrahydroindolizines and indolizidines can be prepared selectively, at low pressu
59 selective synthesis of the chiral piperidine indolizidine, coniceine, is reported.
60 rically pure 1-(dibenzylamino)-3-substituted indolizidines could be further transformed into the corr
61 and several selective transformations of the indolizidine derivatives reported here may find further
62 tion and enables the isolation of sp(3)-rich indolizidine diastereoisomers containing five stereocent
63 achieved, providing facile preparation of an indolizidine framework commonly found in a variety of al
64                                          The indolizidine framework was obtained by means of oxidatio
65 ons for the inversion of the nitrogen at the indolizidine framework, allowing rapid equilibration bet
66 nation reaction for the synthesis of complex indolizidine frameworks is illustrated by application to
67  gem-diamine intermediate that undergoes the indolizidine --> pyrrolizidine Amadori-type rearrangemen
68                Multisubstituted tropanes and indolizidines have been prepared with high regio- and st
69       Herein, 1-(dialkylamino)-3-substituted indolizidines have been straightforwardly synthesized us
70 iperdines, pyrrolidines, pyrrolizidines, and indolizidines, have the potential to become important th
71 y suggests that immunomodulatory activity of indolizidine iminosugars can be tuned by minor structura
72                               New quaternary indolizidine iminosugars, with hydroxymethyl group at th
73               The enzyme is shown to convert indolizidine intermediates into pyrrolizidines through a
74 uoromethylenated dihydroxypyrrolizidines and indolizidines is described.
75 synthesis of mono-, di-, and trihydroxylated indolizidines is presented in four to six steps from Cbz
76 owledge, detection of 5,8-disubstituted (ds) indolizidine iso-217B in T. electrum represents the firs
77 synthetic alkaloid have established that the indolizidine moiety is trans-fused.
78 ve 5,8-disubstituted or 5,6,8-trisubstituted indolizidines; one 1,4-disubstituted quinolizidine; thre
79 n to set up the manno-stereochemistry of the indolizidine precursor.
80  found in well-known natural products (e.g., indolizidine, quinolizidine, and Stemona alkaloids).
81 oyed as the key step to construct the chiral indolizidine ring.
82 n the configuration at the 6-position of the indolizidine ring.
83            A concise entry to functionalized indolizidine scaffolds through a domino 2-aza-Cope-[3 +
84 proach features a concise construction of an indolizidine skeleton by Rh-catalyzed domino hydroformyl
85 5))((t)BuN)]LnE(TMS)(2) to the corresponding indolizidine skeleton in good yield and high diastereose
86  as a key step wherein both the rings of the indolizidine skeleton were built up in one pot following
87 nomeric unit that combines quinolizidine and indolizidine substructures.
88 3,5-diols in the context of polyhydroxylated indolizidine synthesis is demonstrated by an application
89 cted under mild conditions to afford diverse indolizidine systems as single diastereomers in good ove
90 ethyl-1,2-dihydropyridines affords tricyclic indolizidines that incorporate quaternary carbons and up
91                                              Indolizidine type alkaloids have been attractive synthet
92 ategy, substituted tetrahydroindolizines and indolizidines were obtained diastereoselectively in high
93 d azaheterocycles such as pyrrolizidines and indolizidines, which serve as important intermediates in
94 oaddition with unsymmetrical alkynes to give indolizidines with good regio- and stereoselectivity.
95           Its step-by-step transformation to indolizidine yielded 20R,25R or 20R,25S products while t