ライフサイエンスコーパス: inducible

1 eased expression of fibroblast growth factor-inducible 14 (Fn14), Down syndrome critical region 1 (Ds

2 vivo evidence that the host interferon (IFN)-inducible 2'-5'-oligoadenylate synthetase (OAS) and RNas

3 The heat-inducible activity of heat-shock promoters from several

4 We generated a doxycycline-inducible adipose tissue-specific MMP14 overexpression m

5 uced gastrointestinal bleeding and anemia in inducible ALK1-deficient adult mice.

6 erate hPSC lines harboring AAVS1-integrated, inducible and fluorescent dCas9-KRAB and dCas9-VPR trans

7 recently developed platform for implementing inducible and logical control over gene expression in ma

8 This transgenic mouse also provides an inducible and reversible model of hyperaldosteronism to

9 rmation about the prognostic role of hypoxia-inducible angiogenic pathway in G-AgP.

10 Hypoxia-inducible angiogenic pathway involving hypoxia inducible

11 In this study, we create 41 inducible anti-repressors.

12 We have identified a novel mechanism of inducible antibiotic resistance whereby isolates that ap

13 We generated tetracycline-inducible APOL1 expression in human embryonic kidney HEK

14 e re-transfection of knockout podocytes with inducible APOL1-G0, -G1, and -G2 showed no differences i

15 thermore, mdxS3E mice were protected against inducible arrhythmias, related lethality, and the develo

16 osome cargo protein p62/SQSTM1, and a poorly inducible autophagy flux upon proteasome inhibition.

17 Using an inducible auxin-degron system to rapidly deplete RPB1 (t

18 Tetracycline-inducible BACH2 expression resulted in suppression of ph

19 neity revealed that the MCT1 is expressed in inducible beige adipocytes as the emergence of uncouplin

20 ng adipocytes suggesting MCT1 as a marker of inducible beige adipocytes.

21 IDO1 induction in myeloid cells in the inducible bronchus-associated lymphoid tissue (iBALT) li

22 oung and aged mice disrupted smoking-related inducible bronchus-associated lymphoid tissue, induced r

23 Bleb formation is ion specific, inducible by exposing the bilayer to muM concentrations

24 leased by necrotic osteocytes via macrophage-inducible C-type lectin (Mincle), which induced their di

25 ated C-type lectin receptor (CLR) macrophage-inducible Ca2+-dependent lectin receptor (Mincle).

26 ntibiotics and describe a novel mechanism of inducible carbapenem resistance associated with the acqu

27 Inducible cardiomyocyte-specific Tjp1 deletion mice (Tjp

28 We also create inducible CASFx (iCASFx) using the FKBP-FRB chemical-ind

29 at encode anti-CD19 CAR, interleukin-15, and inducible caspase 9 as a safety switch.

30 An inducible catalase system, to test causality for the rol

31 city, we use logic-gated (log) GPC3-synNotch-inducible CD147-CAR to target HCC.

32 Inducible CD4(+)CD25(+) regulatory T (iTreg) cells can b

33 hages are not proinflammatory but interferon-inducible cell and inflammatory macrophages are.

34 Inducible cell-free HIV-1 RNA correlated with HIV-1 DNA,

35 In the last decade, several interferon-inducible cellular proteins, including IFITMs, GILT, ADA

36 -chemokine ligand 9 (CXCL9) is an interferon-inducible chemokine of the CXC family and is increased i

37 Phage-inducible chromosomal island-like elements (PLEs) are ba

38 tivation mapping was possible in all 13 with inducible clinical VTs.

39 Using inducible cMYC overexpression, we demonstrate that post-

40 ute to astrocyte activation, we generated an inducible conditional knock-out mouse in which the Cav1.

41 Here we show that mice with inducible conditional knockdown (KD) of Dsc2 in IEC (Vil

42 agy in neuroblasts using either bafilomycin, inducible conditional mice, or CRISPR/Cas9 gene editing

43 ab5-ZFYVE21-NIK axis and upregulates ICOS-L (inducible costimulator ligand) and PD-L2 (programmed dea

44 tokine levels in CD4(+)/CD8(+) T cells, with inducible costimulator molecule and HLA-DR defining midt

45 ased bioinformatics analysis identified that inducible costimulatory molecule (ICOS)(+) T(FH) cells a

46 Tamoxifen (TAM) inducible Cre recombinase system is an essential tool to

47 y, the Hexb locus was employed for tamoxifen-inducible Cre-mediated gene manipulation in microglia an

48 We applied a doxycycline-inducible CRISPRa technology to increase the expression

49 rst to acheive AAV-mediated, conditional and inducible DAergic knockdown in vivo.

50 The sterol-responsive E3 ubiquitin ligase inducible degrader of the LDLR (IDOL) specifically promo

51 onditional depletion of PICH using the auxin-inducible degron (AID) system resulted in the retention

52 Further assessment using Smc5 cKO and auxin-inducible degron systems demonstrated that absence of SM

53 Here, we decided to use inducible degrons for a more rapid and comprehensive PRD

54 Here, we report that inducible deletion of adipose OGT causes a rapid viscera

55 Here, we observed that inducible deletion of AhR in Lgr5(+) stem cells increase

56 sis was studied in mice with tamoxifen (Tmx)-inducible deletion of ER chaperone Grp78, a key regulato

57 Inducible deletion of IL-4Ralpha demonstrated therapeuti

58 e CASFx (iCASFx) using the FKBP-FRB chemical-inducible dimerization domain, allowing small molecule c

59 Light-inducible dimerization protein modules enable precise te

60 so be regulated by PRKRA (protein interferon-inducible double-stranded RNA-dependent protein kinase a

61 ic proteomic alterations in the brains of an inducible Drosophila melanogaster model of AD expressing

62 First, we utilized a tamoxifen-inducible EC-specific YY1 deficient mouse model and show

63 Here, we generated inducible, EC-specific Pkd2 knockout mice to examine vas

64 Matrix metalloproteinases (MMPs) are inducible endopeptidases that degrade extracellular matr

65 Functionally, genetic-inducible endothelial deletion of Sox17 causes deficient

66 Inducible enhancement of skeletal muscle MHC I in mice d

67 ynthetases (OASs) are a family of interferon-inducible enzymes that require double-stranded RNA (dsRN

68 When testing the effects of inducible EphA4 KO at different timepoints in SOD1(G93A)

69 ial cells while a transgenic model featuring inducible ERBB2DeltaEx16 specifically in the lung epithe

70 dneys have reduced expression of the hypoxia-inducible erythropoietin mRNA.

71 Using inducible expression of MR1, this study demonstrates tha

72 Moreover, inducible expression of PrsS in PrpS-expressing seedling

73 (Oryzias latipes) osteoporosis model, where inducible expression of receptor-activator of nuclear fa

74 Using doxycycline-inducible expression of the neuronal transcription facto

75 TPSs showed distinct and, albeit moderately, inducible expression patterns in response to biotic and

76 Using an inducible expression system, we observed that this ELANE

77 also observed that depletion of the hypoxia-inducible factor (HIF) genes, HIF1A (encoding HIF-1alpha

78 nt role for the transcription factor hypoxia-inducible factor (HIF) in the regulation of innate immun

79 t with variable hypoxia, but whether hypoxia-inducible factor (HIF) is involved is unknown.

80 This study compared effects of five hypoxia-inducible factor (HIF) prolyl hydroxylases (PHD) inhibit

81 alters mitochondrial metabolism and hypoxia inducible factor (HIF) signaling due to iron depletion.

82 Emerging evidence suggests that hypoxia-inducible factor (HIF) signaling plays a fundamental and

83 Oxygen regulates hypoxia-inducible factor (HIF) transcription factors to control

84 nclude the transcriptional regulator hypoxia-inducible factor (HIF), which controls a wide range of o

85 der hypoxic conditions and following hypoxia-inducible factor (HIF1) induction, suggesting that MCT4

86 Hypoxia inducible factor (HIFs) signaling contributes to maligna

87 h the hydroxylase, factor inhibiting hypoxia-inducible factor 1 (FIH-1), we observed increases in epi

88 vation of transcription factors like hypoxia-inducible factor 1 (HIF-1) and c-Myc, yet the impact of

89 man cells requires the activation of hypoxia inducible factor 1 (HIF-1) and not HIF-2.

90 we delineate a pathway controlled by hypoxia-inducible factor 1 (HIF-1) that epigenetically activates

91 molecule 1, IL-10, heme oxygenase 1 hypoxia-inducible factor 1 (HIF-1), monocyte chemotactic protein

92 ctivating the transcription factors, hypoxia-inducible factor 1 (HIF1) and HIF2.

93 , there is a significant increase of hypoxia inducible factor 1 alpha (HIF-1alpha), but a reduction o

94 owards glycolysis with activation of hypoxia-inducible factor 1 subunit alpha (HIF-1alpha) and phagos

95 the downstream transcription factors hypoxia-inducible factor 1-alpha and c-Myc, which together promo

96 Increased hypoxia-inducible factor 1-alpha expression in the MP group was

97 Expression of hypoxia-inducible factor 1-alpha peaked in the SCS-group after 8

98 Increased Hypoxia Inducible Factor 1A (HIF1A)-associated signaling correla

99 We hypothesized that hypoxia inducible factor 1alpha (HIF-1alpha) in CNS respiratory

100 The hypoxia-inducible factor 1alpha (HIF-1alpha) is critically invol

101 We hypothesized that hypoxia inducible factor 1alpha (HIF-1alpha), an O(2) -sensitive

102 We identified induction of CD36 and hypoxia-inducible factor 1alpha (HIF1alpha) proteins as contribu

103 ation modulated the stabilization of hypoxia-inducible factor 1alpha (HIF1alpha) to upregulate the VE

104 ucible factor 2alpha (HIF2alpha) and hypoxia-inducible factor 1alpha (HIF1alpha), were enriched in th

105 within knockout cardiomyocytes; (3) Hypoxia-inducible factor 1alpha protein instability was associat

106 e show that the transcription factor hypoxia-inducible factor 2 alpha (Hif2alpha), which is induced i

107 transcription factor-binding motifs, hypoxia-inducible factor 2alpha (HIF2alpha) and hypoxia-inducibl

108 ccRCC downstream of VHL loss besides hypoxia-inducible factor 2alpha (HIF2alpha).

109 ion changes that suggested increased hypoxia-inducible factor 2alpha signaling.

110 stasis maintaining pathway involving Hypoxia-inducible factor 2alpha.

111 parenchymal injury transcripts (eg, hypoxia-inducible factor EGLN1).

112 GPe PV(+) neurons were enriched for hypoxia-inducible factor family binding motifs.

113 In addition to collagen P4Hs and hypoxia-inducible factor P4Hs, a third P4H-the poorly characteri

114 ription, distinct from the classical hypoxia-inducible factor pathway.

115 2OG oxygenases, e.g. screens of the hypoxia-inducible factor prolyl-hydroxylase inhibitors revealed

116 Whether antenatal or postnatal HIF (hypoxia-inducible factor) augmentation can preserve lung structu

117 in phosphatase 2) regulates the HIF (hypoxia-inducible factor)/PHD-2 (prolyl hydroxylase 2)-constitut

118 ritical importance of high levels of hypoxia-inducible factor, HIF2alpha/EPAS1, and the nuclear-encod

119 ducible angiogenic pathway involving hypoxia inducible factor-1 alpha (HIF-1alpha), vascular endothel

120 itors (PHI) promote stabilization of hypoxia-inducible factor-1 alpha and affect signaling cascades o

121 eic recipients resulted in increased hypoxia-inducible factor-1 alpha expression and reduced apoptosi

122 Here, we report that hypoxia-inducible factor-1alpha (HIF-1alpha) is crucial for the

123 s secrete high levels of GM-CSF in a hypoxia-inducible factor-1alpha (HIF1alpha)- and a NF-kappaB-dep

124 nt of PH, mice lacking expression of hypoxia-inducible factor-1alpha in the Ly6C(lo) monocyte lineage

125 2), phosphorylated PKM2, HIF-1alpha (hypoxia-inducible factor-1alpha), and lactate.

126 , succinate, adenosine triphosphate, hypoxia-inducible factor-1alpha, nuclear factor erythroid 2-rela

127 decreased expression of HIF-2alpha (hypoxia-inducible factor-2alpha)-regulated genes, and tobacco sm

128 Hypoxia activates hypoxia-inducible factor-dependent signaling, which in turn regu

129 l processes, including regulation of hypoxia-inducible factor-mediated adaptation to hypoxia, extrace

130 activated protein kinase (AMPK), and hypoxia-inducible factors (HIF-1alpha and HIF-2alpha)-can exert

131 Hypoxia-inducible factors (HIFs) and the HIF-dependent cancer ha

132 Hypoxia-inducible factors (HIFs) are critical regulators of the

133 n the constitutive activation of the hypoxia-inducible factors (HIFs) HIF-1 and HIF-2 and their downs

134 o PHD3) regulate the activity of the hypoxia-inducible factors (HIFs) HIF-1 and HIF-2, transcription

135 This Review focuses on the role of hypoxia-inducible factors (HIFs) in hypertension, type 2 diabete

136 acid (FA) transport, is repressed by hypoxia-inducible factors (HIFs), reducing FA oxidation (FAO).

137 e response to hypoxia is mediated by hypoxia-inducible factors (HIFs).

138 gh transcriptional regulators called hypoxia-inducible factors (HIFs).

139 rate up to 44,000 transcribed barcodes in an inducible fashion at any point during development or adu

140 Inducible fluorescent histone 2B fusion protein (H2B-FP)

141 th ubiquitously expressed Cre/ER and the Cre-inducible fluorescent reporter YFP.

142 Here, we generated fibroblast-specific inducible focal adhesion kinase (FAK) knockout (cKO) mic

143 ed the underlying molecular mechanisms using inducible gain and loss of function approaches in ILC2s

144 We tested this model using the inducible GAL1 promoter to make the Whi5 concentration i

145 ress this limitation, we have used the light-inducible GAVPO transactivator in combination with two g

146 nterface and show its utility using a ligand-inducible gene circuit and toehold switch-based sensors

147 o compare expression of 1alpha,25(OH)(2)D(3)-inducible gene expression signatures in clinical samples

148 roach to identify transcription factor-based inducible gene expression systems.

149 Further themes include mechanisms of inducible gene expression, the coordination of gene regu

150 Using reporter mice with SOX2-driven, inducible gene expression, we show that ONLR-NPCs genera

151 ceptor 7 (TLR7) and, possibly, retinoic acid-inducible gene I (RIG-I) after viral sensing.

152 These defective RNAs bind to retinoic acid-inducible gene I (RIG-I) and initiate mitochondrial anti

153 se in viral RNA recognition by retinoic acid-inducible gene I (RIG-I), thereby stimulating type I int

154 interferon (IFN) response in a retinoic acid-inducible gene I (RIG-I)-dependent manner and readily ac

155 Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key s

156 genome replication can trigger retinoic acid-inducible gene I (RIG-I)/mitochondrial antiviral signali

157 l-like receptor 7 and possibly retinoic acid-inducible gene I.

158 IP-Seq analysis identified Klk1b21 as an ICI-inducible gene in AF2ERKI uterus.

159 ession of the recently characterized, immune-inducible gene Induced by Infection (IBIN) was diminishe

160 es suggest that Mcub is a protective cardiac inducible gene that reduces mitochondrial Ca(2+) influx

161 We find that Vgf nerve growth factor inducible gene up-regulation is a common transcriptional

162 res the Gadd45 (Growth arrest and DNA-damage-inducible) gene family, very little is known about how t

163 xcl10), APC activation (e.g., Cd86), and IFN-inducible genes (e.g., Ifit3, Ifit5, Irf7, Isg15, orMx1)

164 emarkably, a significant proportion of auxin inducible genes and of targets of the AUXIN RESPONSE FAC

165 own as a positive elongation factor for many inducible genes by releasing paused RNAPII near the tran

166 BdRAM1 showed constitutive expression of AM-inducible genes even in the shoots.

167 s LTR12C elements upstream of the interferon-inducible genes GBP2 and GBP5 that encode for broad-spec

168 the correct expression of a subset of auxin-inducible genes In this work, we analyzed the response t

169 most likely by regulating a subset of auxin inducible genes related to cell expansion.

170 ibosomal protein L4 encoded by the cytokinin-inducible genes RPL4A and RPL4D, and that RPL4 loss-of-f

171 equencing revealed that a number of cytokine-inducible genes shared this heterogeneous response patte

172 Herein, we used inducible genetic depletion and two distinct pharmacolog

173 Tamoxifen-inducible genetic lineage tracing of mature adipocytes a

174 Using inducible genetic switches, we demonstrate that swimming

175 Interferon-inducible GTPase 1 (IIGP1) is a mouse-specific ISG and b

176 Using conditional-inducible H2A.Z knockout (cKO) mice, we showed that H2A.

177 Mice with a tamoxifen-inducible, hepatocyte-specific Atg5 knockout were simila

178 ritance, we used a Schizosaccharomyces pombe inducible heterochromatin formation system to perform a

179 abidopsis thaliana cryptochrome 2, the light-inducible homo-interaction of the intracellular domain o

180 nal programming by including oligodendrocyte-inducible hPSCs with unmodified hPSCs to generate cerebr

181 n of Mcl1 (Mcl1(DeltaIEC) mice) or tamoxifen-inducible IEC-specific disruption of Mcl1 (i-Mcl1(DeltaI

182 2) IL-4Ralpha(-/lox) mice, a tamoxifen (TAM)-inducible IL-4Ralpha knockdown model to investigate the

183 s and, by extension, vulnerability to stress-inducible illnesses.

184 and transgenic animals expressing NF-kappaB inducible imaging reporter.

185 sm, we utilize epidermal growth factor (EGF)-inducible immediate early genes (IEGs).

186 The clinical VTs were inducible in 13 patients (62%), whereas 6 patients had p

187 These changes were stable, inducible in adults after the termination of the critica

188 aryngeal carriage of Bordetella pertussis is inducible in humans and to define the microbiological an

189 of the most radical is SCRaMbLE, a system of inducible in vivo deletion and rearrangement of syntheti

190 olic defects in the accumulation of pathogen-inducible indole glucosinolate-derived compounds, sugges

191 rotein 4 (RTP4) as a potent interferon (IFN)-inducible inhibitor of human pathogens in the Flavivirid

192 Using mice with inducible intestinal epithelial cell (IEC)-specific dele

193 rformed to determine the prognostic value of inducible ischemia or late gadolinium enhancement by CMR

194 In multivariable Cox regression, inducible ischemia was an independent predictor of a hig

195 engineered V5-FOXL2(WT)- and V5-FOXL2(C134W)-inducible isogenic cell lines and performed chromatin im

196 , the C. elegans homolog of a mammalian Salt-Inducible Kinase (SIK) that signals sleep pressure, have

197 ation of HDAC7 by the CaMK group member salt-inducible kinase 1 (SIK1) stabilized the deacetylase, le

198 ein upregulates the serum and glucocorticoid inducible kinase SGK1.

199 de receptor, SGK-1/serum- and glucocorticoid-inducible kinase, and specific isoforms of DAF-16/FOXO t

200 Comparing knockout and inducible knockdown systems, we find that acute depletio

201 ypothesis was tested by generating tamoxifen-inducible knockout mouse models of Cyp26b1 alone or with

202 te-binding protein 2 (GBP2) is an interferon-inducible large GTPase which is crucial to the protectiv

203 for the accurate assessment and diagnosis of inducible laryngeal obstruction.

204 However, actively infected astrocytes were inducible, leading to increased expression of viral prot

205 nology to show, for the first time, that the inducible lysophosphatidylcholine acyltransferase 2 (LPC

206 ogy (PH) domains 2 (ADAP2), gamma-interferon-inducible lysosome/endosome-localized thiolreductase (GI

207 tner, CTCF, interacted with HSF1 in a stress-inducible manner and functions in repression of specific

208 ely active Eef1a1 locus in a Cre recombinase-inducible manner.

209 controls these diverse functions, we used an inducible method to reroute TPD54 to mitochondria.

210 al dysfunction and slows degeneration in the inducible microbead occlusion model of glaucoma in rat.

211 The I307N Rho mouse is a light-inducible model of autosomal dominant RP.

212 , with or without a mutation in Tlr4, in our inducible mouse model of ocular hypertension by injectio

213 TR), was depleted from POMC neurons using an inducible mouse model.

214 haracterization of a mouse model that allows inducible Msi1 overexpression in a temporal and tissue-s

215 issue of the JCI, Bosnakovski et al. used an inducible, muscle-specific human DUX4 to reproduce the l

216 ity of 90% (CI, 88% to 92%) for exclusion of inducible myocardial ischemia.

217 not generally allow users to safely exclude inducible myocardial ischemia.

218 nd at least 90% sensitivity for exclusion of inducible myocardial ischemia.

219 A wheat nitrate-inducible NAC transcription factor, TaNAC2, plays a crit

220 is a member of RNS produced from arginine by inducible Nitric Oxide Synthase (iNOS) enzyme.

221 odels, we showed that radiotherapy increased inducible nitric oxide synthase (iNOS) in the tumor tiss

222 tory and pro-apoptotic signaling mediated by inducible nitric oxide synthase (iNOS), transforming gro

223 coding guanylate-binding proteins (GBPs) and inducible nitric oxide synthase (iNOS), which we found t

224 d prolonged corneal allograft survival in an inducible nitric oxide synthase (iNOS)-dependent manner.

225 eptors (TLRs) on the host cell, it activates inducible nitric oxide synthase (NOS2) which instantly f

226 es presented distinct anti-inflammatory (low inducible nitric oxide synthase and lower tumour necrosi

227 Increased activities of inducible nitric oxide synthase and NADPH oxidase 1 enzy

228 tokines on beta cells, which are mediated by inducible nitric oxide synthase expression and beta-cell

229 cells and neurons showed increased levels of inducible nitric oxide synthase, another indicator of ce

230 ytokines possibly by affecting the NF-kappaB-inducible nitric oxide synthase-endoplasmic reticulum st

231 Here, we engineer inducible nitrogenase activity in two cereal endophytes

232 , there is deficient granuloma formation and inducible NO synthase (iNOS) induction, increased dissem

233 displays properties of a heme chaperone for inducible NO synthase, here we investigated whether heme

234 d and reversible optogenetic tool, the light-inducible nuclear exporter, to control the subcellular l

235 Here, we use an inducible nuclear pore complex blockade to monitor the k

236 t in 60% of the patients and a VT was either inducible or sustained/incessant in 85% of the cases.

237 We demonstrate the utility of the tightly inducible P(BAD)-riboswitch construct using the dynamic

238 Using an inducible Pol II-degradation system that we previously e

239 Large numbers of stress-inducible poly(A) sites could not be linked with known,

240 the upregulation of downstream effector TCDD-inducible poly(ADP-ribose) polymerase (TiPARP) during in

241 ecture, we evaluated the performance of each inducible promoter as discrete operations, and as couple

242 hat we term "TraDIS-Xpress" that combines an inducible promoter into the transposon cassette.

243 ter library and over 327,000 sequences in an inducible promoter library.

244 P (trc) promoter (Ptrc-cfrA) or the arsenite-inducible promoter P (arsB) (Pars-cfrA).

245 A315T) mice) using a tetracycline-controlled inducible promotor system.

246 x type E3 ubiquitin ligase, designated as P3-inducible protein 1 (P3IP1), which interacts with OsNRPD

247 In those with SVR, interferon-inducible protein 10, ATX, and Mac2BP levels declined by

248 Plasma HCV, soluble CD14 (sCD14), interferon-inducible protein 10, soluble CD163 (sCD163), interleuki

249 hisms in inflammasome genes interferon gamma inducible protein 16 (IFI16) and absent in melanoma 2 (A

250 Using inducible protein degradation, we show that PAR-6 and PK

251 lysis of pigment binding by plant high-light-inducible protein homologs, called ONE-HELIX PROTEINS (O

252 genetic approach for cell-type-specific drug-inducible protein synthesis inhibition that enables rapi

253 Loss of this type-I-interferon-inducible protein, which we refer to as 'TLR adaptor int

254 binding ability of cyanobacterial high-light-inducible proteins has been studied in detail.

255 To address this need, we engineer an inducible quorum sensing system which enables precise tu

256 enable organelle repositioning through light-inducible recruitment of motors to specific organelles.

257 These results underscore the utility of inducible RNA tagging and challenge current models of te

258 Here, we use inducible RNA tagging experiments to show that immediate

259 ognize two nonclassical NLSs within the cold-inducible RNA-binding protein (CIRBP).

260 vo slice electrophysiology of transgenic Cre-inducible Rosa-eGFP-L10a mice in combination with retrog

261 Furthermore, we show that cytokine-inducible SH2-containing protein (CIS) is crucial in lim

262 ANC-1 cell invasion by using the doxycycline-inducible shRNA system.

263 tep aerobics in humans markedly reduced WNT1-inducible signaling pathway protein 1, WISP1, which lead

264 DNA load, intact proviral DNA levels, and in inducible SIV reservoir in lymph nodes (LNs) of morphine

265 ivity via gp130 to productive replication in inducible SLK (epithelial) cells, absence of detectable

266 ther, lineage tracing with lipophilic dye or inducible Sox10-Cre suggests that post-embryonic enteric

267 of a tightly controlled ObLiGaRe doxycycline inducible SpCas9 (ODInCas9) transgene and its use in tar

268 ecently been proposed to be interferon (IFN) inducible, suggesting that SARS-CoV-2 may exploit this p

269 e-light-regulated repressor with a red-light-inducible switch.

270 Here, we developed an inducible system of three-dimensional (3D) collective in

271 division would greatly benefit from a fast, inducible system.

272 expression in Tph1 deficient ILC2s including inducible T cell co-stimulator (Icos).

273 n-6 and the costimulatory molecules CD40 and inducible T cell costimulator ligand was significantly r

274 Inducible T-cell costimulator (ICOS) is a specific marke

275 espite diverse functions, they are all three inducible through TLR4 signaling but with distinct kinet

276 Here, we generated mice with tamoxifen-inducible Thy1-Cre mediated ERalpha inactivation during

277 erial infections in farm animals by bacteria-inducible tissue-specific expression of PG-1 transgene.

278 endoplasmic reticulum-associated, interferon-inducible) to enhance viral infectivity.

279 s (PHDs) that regulate the levels of hypoxia-inducible transcription factor alpha (HIFalpha).

280 iated by the alphabeta-heterodimeric hypoxia-inducible transcription factors (alpha,beta-HIFs) which

281 Hypoxia-inducible transcription factors (HIFs) directly dictate

282 uN3A in rat hippocampal neurons promotes the inducible transcription of a subset of NMDAR-sensitive g

283 lular redistribution of proteins, as well as inducible transcriptional activation when coupled with t

284 Inducible transcriptional programs mediate the regulatio

285 ythematosus (SLE) and can be tracked via IFN-inducible transcripts in blood.

286 poietic cells is reversible, we developed an inducible transgene to restore expression of DNMT3A in t

287 The interferon-inducible transmembrane (IFITM) proteins belong to the D

288 a D. melanogaster hsp70 promoter for a heat-inducible transposase helper plasmid, and creating vecto

289 Collectively, our results identify IFN-I-inducible TRIM21 as a negative regulator of innate immun

290 Furthermore, we identified a P3-inducible U-box type E3 ubiquitin ligase, designated as

291 AIPL1 interacts with the cytokine-inducible ubiquitin-like modifier FAT10, which gets cova

292 ctory chronic spontaneous urticaria (without inducible urticaria) for >2 months are reported here.

293 his study, we identified a pharmacologically inducible vasculoprotective mechanism in pulmonary arter

294 Intra-NAc infusions of Cre-inducible viral vectors containing stimulatory (hM3Dq) o

295 nsitivity and 81% specificity for predicting inducible VT (area under the curve, 0.81; P<0.001).

296 Inducible VT predicts mortality.

297 extreme cutoffs for ruling-out and ruling-in inducible VT, RV LGE >10 cm(3) was 100% sensitive and >3

298 d >36 cm(3) was 100% specific for predicting inducible VT.

299 sh to test whether plasticity in the form of inducible warm tolerance also evolved.

300 umococcal virulence factor, to be externally inducible (YES gate) or to act as an IMPLY gate (only ex