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1 ase activity and increased expression of IFN-inducible genes.
2 al-time polymerase chain reaction of hypoxia-inducible genes.
3 factor is involved in modulating other ATRA-inducible genes.
4 other genes that are not recognized as MyoD-inducible genes.
5 loci, which apparently do not accumulate at inducible genes.
6 contributed to basal expression of many LPS-inducible genes.
7 enome and successfully identified novel zinc-inducible genes.
8 associated genes and repress differentiation-inducible genes.
9 ), as being encoded by Mlx-dependent glucose-inducible genes.
10 itioned in promoters upstream of most stress-inducible genes.
11 and downregulates the expression of hypoxia-inducible genes.
12 ells selectively upregulate a set of hypoxia-inducible genes.
13 s degraded by DCP2 are expressed proximal to inducible genes.
14 ays a role in stabilizing mRNAs of some heat-inducible genes.
15 anscripts, and enhances activation of stress-inducible genes.
16 , LDGs display the highest expression of IFN-inducible genes.
17 ry elements and maintain low basal levels of inducible genes.
18 ly enriched in ISGs, particularly for highly inducible genes.
19 associated macrophage expression of IFNgamma-inducible genes.
20 ice showed upregulation of several IFN-gamma-inducible genes.
21 stimulation and is strongly enriched for IFN-inducible genes.
22 iating enhancer-promoter looping at ecdysone-inducible genes.
23 cluding CD16A signaling and interferon-gamma-inducible genes.
24 Toll-like receptor 3 (TLR-3), retinoic acid-inducible gene 1 (RIG-1), and nucleotide-binding oligome
25 and Lujo viruses, can inhibit retinoic acid-inducible gene 1 (RIG-i) and Melanoma Differentiation-As
28 mRNA fragments produced engage retinoic-acid inducible gene 1 (RIG-I), a cytosolic sensor of RNA viru
29 n-associated protein 5 (MDA5), retinoic acid-inducible gene 1 (RIG-I), and mitochondrial antiviral si
30 al for sustained and amplified retinoic acid-inducible gene 1 (RIG-I)-induced type I interferon expre
31 ted by the cytosolic receptors retinoic acid-inducible gene 1 and melanoma differentiation-associated
33 e we show that MAVS and RIG-I (retinoic acid-inducible gene 1), an RLR family member, also have a rol
34 tors (Toll-like receptor 7 and retinoic acid-inducible gene 1), HCV RNA induced consistent and broad
35 ion of the NKG2D ligand, retinoic acid early inducible gene 1, also increased at the ocular surface a
36 is required for both TRIF- and retinoic acid-inducible gene 1-dependent signaling cascades to induce
37 s that are transmitted via the retinoic acid-inducible gene 1-like receptor (RLR), nucleotide-binding
39 nduced by TLR2, TLR3, TLR9, or retinoic acid-inducible gene 1/melanoma differentiation-associated pro
40 oll-like receptor 7 (TLR7) and retinoic acid inducible gene-1 (RIG-I) for the activation of innate-im
41 bition was dependent on Rig-I (retinoic acid-inducible gene-1), IRF3, and MxA (myxovirus resistance g
42 s and functional analyses identified hypoxia-inducible gene 2 (HIG2), a HIF-1 target, as a new inhibi
43 Here we show that the LD protein hypoxia-inducible gene 2 (Hig2/Hilpda) functions to enhance lipi
44 al cells with KSHV, growth arrest DNA damage-inducible gene 45 beta (GADD45B) is one of the most repr
47 inib, with a concomitant increase of mitogen-inducible gene 6 (Mig6), a negative regulator of EGFR th
48 lts in upregulated expression of the mitogen-inducible gene 6 (MIG6), a negative regulator of EGFR.
49 ignaling and decreased expression of mitogen-inducible gene 6 (MIG6), a negative regulator of epiderm
50 ion potently increased the levels of mitogen-inducible gene 6 (MIG6), which inhibits EGFR and facilit
51 on-associated protein, tumor necrosis factor-inducible gene 6 protein, in the extracellular matrix.
53 RNA quantitation, we found that multiple IFN-inducible genes (affecting lymphocyte trafficking, diffe
55 hat, mechanistically, DDT is a novel hypoxia-inducible gene and direct target of HIF1alpha and HIF2al
56 ng the ribosome binding site strength of the inducible gene and shifts when modifying the plasmid cop
57 n associated with increased expression of GA-inducible genes and decreased ABA accumulation, apparent
59 reduced responsiveness of jasmonic acid (JA)-inducible genes and enhanced susceptibility to the necro
60 gions of active chromatin in the vicinity of inducible genes and enhancers that regulate immune respo
62 emarkably, a significant proportion of auxin inducible genes and of targets of the AUXIN RESPONSE FAC
66 we observed that ATF3 itself is a type I IFN-inducible gene, and that ATF3 further modulates the expr
67 identified two interrelated pathways: 1) IFN-inducible genes, and 2) innate receptors for cellular da
68 manner, indicating that the findings at this inducible gene are likely generalizable to a large set o
70 interferon gamma (IFN-gamma), many IFN-gamma-inducible genes are induced more rapidly and more strong
71 alysis of active RNAPII reveals that hypoxia-inducible genes are paused and active prior to their ind
74 he female birds expressed a set of known IFN-inducible genes at much higher levels than male cells un
75 ase in the expression of a subset of hypoxia-inducible genes at the metastatic site, suggesting the p
77 own as a positive elongation factor for many inducible genes by releasing paused RNAPII near the tran
78 correlate repression of transcription of IFN-inducible genes by the E1B 55-kDa protein with protectio
79 9) impair repression of transcription of IFN-inducible genes, by the E1B, 55-kDa protein, consistent
80 nterface and show its utility using a ligand-inducible gene circuit and toehold switch-based sensors
81 s well as transgenic human cells carrying an inducible gene circuit for the on-demand secretion of er
83 is dominated by overexpression of interferon-inducible genes (consisting of both type I and type II i
84 Ngs1 is targeted to the promoters of GlcNAc-inducible genes constitutively by the transcription fact
87 ce, SP-A inhibited upregulation of IFN-gamma-inducible genes (CXCL10, RARRES3, and ETV7) as well as S
93 xcl10), APC activation (e.g., Cd86), and IFN-inducible genes (e.g., Ifit3, Ifit5, Irf7, Isg15, orMx1)
98 sulted in increased expression of interferon-inducible genes, especially those involved in type I int
102 on a combination of stem cell delivery, heat-inducible gene expression and mild heating with high-int
104 ALENs), and has enabled us to insert a 15-kb inducible gene expression cassette at a defined locus in
105 the characterization of an engineered light-inducible gene expression circuit in yeast and compare t
106 of histone acetylation and enhanced ethylene-inducible gene expression in an EIN2-dependent manner.
108 tively, spatially and temporally controlling inducible gene expression in Arabidopsis that overcomes
109 S patients induced a significantly lower IFN-inducible gene expression in comparison with healthy con
112 o compare expression of 1alpha,25(OH)(2)D(3)-inducible gene expression signatures in clinical samples
113 tergroup differences in 1alpha,25(OH)(2)D(3)-inducible gene expression signatures were modest and var
114 the PiggyBac transposon and a Tet-On 3G drug-inducible gene expression system to achieve versatile in
119 anslation, are commonly used in research for inducible gene expression using Tet-ON/Tet-OFF systems.
120 ate increased IFNAR signaling, increased IFN-inducible gene expression, and enhanced proliferation an
122 To systematically identify regulators of inducible gene expression, we performed high-throughput
129 res the Gadd45 (Growth arrest and DNA-damage-inducible) gene family, very little is known about how t
130 To assess the importance of specific plant-inducible genes for L. lactis growth in ATL, xylose meta
132 s LTR12C elements upstream of the interferon-inducible genes GBP2 and GBP5 that encode for broad-spec
133 le-cell RNA sequencing, we found that immune-inducible genes had become constitutively upregulated.
135 These defective RNAs bind to retinoic acid-inducible gene I (RIG-I) and initiate mitochondrial anti
136 onjugated beads indicated that retinoic acid-inducible gene I (RIG-I) and interferon gamma-inducible
137 N response by interacting with retinoic acid inducible gene I (RIG-I) and its recruitment to mitochon
140 interacting with and degrading retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-as
141 5 specifically interacted with retinoic acid-inducible gene I (RIG-I) and negatively regulated its ac
142 f Toll-like receptor 3 (TLR3), retinoic acid-inducible gene I (RIG-I) and several antiviral IFN-stimu
143 e in cancer cells that reduced retinoic acid-inducible gene I (RIG-I) expression and impeded the abil
144 ha and the IFN-stimulated gene retinoic acid-inducible gene I (RIG-I) in response to cyclic GMP-AMP,
146 that the sensing of IAV RNA by retinoic acid inducible gene I (RIG-I) initiates ZBP1-mediated cell de
149 e pattern recognition receptor retinoic acid-inducible gene I (RIG-I) plays a key role in influenza A
151 In infected hepatocytes, the retinoic acid-inducible gene I (RIG-I) protein recognizes 5' triphosph
155 ion via the cytosolic helicase retinoic acid-inducible gene I (RIG-I), a ubiquitously expressed recep
156 al antiviral signaling (MAVS), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation-a
157 genes following stimulation of retinoic acid-inducible gene I (RIG-I), it could selectively impair th
158 ivation of the RNA sensor, the retinoic acid-inducible gene I (RIG-I), leading to inhibition of IFN p
159 cytoplasmic sensors encoded by retinoic acid-inducible gene I (RIG-I), melanoma differentiation-assoc
161 se in viral RNA recognition by retinoic acid-inducible gene I (RIG-I), thereby stimulating type I int
162 interferon (IFN) response in a retinoic acid-inducible gene I (RIG-I)-dependent manner and readily ac
163 ns homologous to the mammalian retinoic acid inducible gene I (RIG-I)-like helicase (RLH) family of c
164 likely through suppression of retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) activation.
165 tion of viral pathogens by the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family resu
166 as viral RNA receptors of the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family.
168 el, we found that blocking the retinoic acid-inducible gene I (RIG-I)-like receptor pathway or the IF
172 nfection trigger a coordinated retinoic acid-inducible gene I (RIG-I)-Toll-like receptor (TLR) signal
175 genome replication can trigger retinoic acid-inducible gene I (RIG-I)/mitochondrial antiviral signali
176 is sensed in the cytoplasm by retinoic acid-inducible gene I (RIG-I, also known as DDX58), which req
178 lus) and 5' poly(U) HCV RNA (a retinoic acid-inducible gene I [RIG-I] stimulus) from two viral genoty
180 at functions downstream of the retinoic acid-inducible gene I family of pattern recognition receptors
182 tions of each RNP subunit with retinoic acid-inducible gene I protein (RIG-I) from mammalian and avia
187 ll lines pointed to the RIG-I (retinoic acid inducible gene I)-like receptor Laboratory of Genetics a
189 indicated that TLR as well as retinoic acid-inducible gene I-like helicase (RLH) signaling contribut
190 erferon (IFN) signaling in the retinoic acid-inducible gene I-like receptor (RLR) pathway was blocked
191 ainst RNA viruses that uses an retinoic acid-inducible gene I-like receptor-independent pathway to en
192 r inflammatory cytokines after retinoic acid-inducible gene I-like receptors recognize intracellular
193 t include Toll-like receptors, retinoic acid-inducible gene I-like receptors, and cytosolic DNA senso
194 associated patterns by several retinoic acid-inducible gene I-like receptors, toll-like receptors, an
197 of IFN-beta synthesis via the retinoic acid-inducible gene I/melanoma differentiation-associated pro
198 e and independent of the known retinoic acid-inducible gene I/mitochondrial antiviral-signaling prote
199 -like receptors (RLRs), RIG-I (retinoic acid-inducible gene I; encoded by DDX58) and MDA5 (melanoma d
201 y identifying a novel role for retinoic acid-inducible gene-I (RIG-I) as a central regulator of endot
202 of the TLR4 and the antiviral retinoic acid-inducible gene-I (RIG-I) pathways with clinical outcomes
203 by the innate immune receptor Retinoic Acid Inducible Gene-I (RIG-I), whose activation triggers a Ty
205 nsors, Toll-like receptors and retinoic-acid inducible gene-I (RIG-I)-like receptors in particular, w
206 onse to HBV infection, through retinoic acid-inducible gene-I (RIG-I)-mediated sensing of the 5'-epsi
209 ed antiviral immunity, reduced retinoic acid-inducible gene-I, and IFN/cytokine and chemokine respons
211 n sensing cytosolic viral RNA, retinoic acid-inducible gene-I-like receptors (RLRs) interact with the
212 patterns of TFII-I at active, repressed, or inducible genes, identify novel TFII-I interacting prote
216 nges may be due to increased levels of light-inducible genes in cavefish, including clock repressor p
218 IFNAR1 normalized the overexpression of IFN-inducible genes in graft-versus-host disease skin and ma
221 er, H3S10ph also marks regulatory regions of inducible genes in interphase mammalian cells, implicati
222 both developmental and inflammatory stimulus-inducible genes in macrophages, but the mechanisms under
224 revealed that WRKY70 represses many pathogen-inducible genes in the absence of pathogens, yet is requ
225 th increased epithelial expression of IL-6TS-inducible genes in the absence of systemic inflammation.
226 the correct expression of a subset of auxin-inducible genes In this work, we analyzed the response t
227 DNA microarray analysis to identify IFN-beta-inducible genes in vitro and then used this set of genes
229 ngly increased expression of a number of IFN-inducible genes, in addition to enhanced T-bet synthesis
231 in stimulating expression of a subset of IFN-inducible genes, including a key regulator of the IFNgam
232 tion, which was accompanied by reductions in inducible genes, including Comtd1 in vitro and Fstl1 and
233 uction of interferon beta (IFN-beta) and IFN-inducible genes, including the melanoma differentiation-
234 ession of the recently characterized, immune-inducible gene Induced by Infection (IBIN) was diminishe
237 de that GFAT2 should be considered a new LPS-inducible gene involved in regulation of protein O-GlcNA
238 itations by developing single-step optimized inducible gene knockdown or knockout (sOPTiKD or sOPTiKO
240 ockout hPSC lines, as well as stage-specific inducible gene knockout during hPSC differentiation.
242 he auxin reporter DR5rev::GFP, and the auxin-inducible genes MONOPTEROS, INDOLE-3-ACETIC ACID INDUCIB
243 that induces myriad target genes, those p53-inducible genes most critical for tumor suppression rema
249 ting protein (TXNIP), an exquisitely glucose-inducible gene previously identified as a critical media
250 We propose that altered expression of light-inducible genes provides a selective advantage to cavefi
252 together, these results suggest that hypoxia-inducible genes, regulated by VHL, are essential for nor
253 he same TF can be linked to constitutive and inducible gene regulation via distinct combinations of a
257 of an integrated gene-trap reporter, whereas inducible gene restoration is afforded by Flp-dependent
258 leads to decreased expression of interferon-inducible genes, resulting in significantly compromised
259 tion domain-like receptor, and retinoic acid-inducible gene RIG-like receptor pathways were mapped ba
260 tion domain-like receptor, and retinoic acid-inducible gene RIG-like receptor signaling pathways in r
261 latory factor 3 (IRF3) via the retinoic acid inducible gene (RIG)-I/mitochondrial antiviral signaling
263 ibosomal protein L4 encoded by the cytokinin-inducible genes RPL4A and RPL4D, and that RPL4 loss-of-f
265 equencing revealed that a number of cytokine-inducible genes shared this heterogeneous response patte
266 n of dose-dependent induction of Bisphenol A inducible genes showed a weak gene activation peak at a
268 pression of heavy metal-inducible and stress-inducible genes, stress kinase cascades, and apoptosis.
270 nds to positively correlate with several IFN-inducible genes, suggesting the potential role of AIM-2
272 stem is one of the most promising chemically inducible gene switches in plants because of its potenti
274 ercome these limitations, we designed a new, inducible gene-targeting system by introducing an in-fra
275 es suggest that Mcub is a protective cardiac inducible gene that reduces mitochondrial Ca(2+) influx
276 aled that approximately 85% of the NF-kappaB-inducible genes that are down-regulated by the R30A muta
277 T cells, DNA damage and replication, and IFN-inducible genes that correlated with IL-15 treatment and
278 nce the expression of several glucocorticoid-inducible genes that have anti-inflammatory potential.
279 leads to decreased expression of several IFN-inducible genes that mediate important biological functi
280 ed enhancer element present in multiple zinc-inducible genes, the high zinc activation (HZA) element.
281 renhancers to preferentially regulate highly inducible genes, thereby providing new insights into the
282 ation significantly inhibits over 60% of TPA-inducible gene transcription and impairs cell proliferat
283 ogen and hypoxia on AR-dependent and hypoxia-inducible gene transcription, protein expression, cell p
293 ral SA-dependent and SA-independent pathogen-inducible genes were higher in cbp60a plants than in the
294 The expression levels of salicylic acid (SA)-inducible genes were higher, but those inducible by jasm
295 , various osmotic stress/abscisic acid (ABA)-inducible genes were up-regulated in cpl1-2, and the exp
296 ance of seedlings and the expression of heat-inducible genes whereas knockout of GAPCs has opposite e
298 ays revealed effective inhibition of hypoxia-inducible genes with relatively minimal perturbation of