ライフサイエンスコーパス: inhalant

1 nd nasally administered as Nasacort AQ nasal inhalant.

2 ding to potential exposure to asthma-causing inhalants.

3 dust mite (10 trials), grass pollen or other inhalants.

4 ns (27 of 51 users [52.9%]); and respiratory inhalants (19 of 45 [42.2%]).

5 %), hallucinogen (49.4%), heroin (8.7%), and inhalant (30.4%) use.

6 Until recently, inhalant abuse and dependence have been overlooked as se

7 ping prevention and treatment programmes for inhalant abuse and dependence.

8 demonstrated a decrease in the prevalence of inhalant abuse, but overall rates remain high.

9 eviews the most recent epidemiologic data on inhalant abuse, summarizes the types of substances used

10 eveloping effective treatment strategies for inhalant addicts.

11 delivered signal to promote sensitization to inhalant aeroallergen, which may account for one mechani

12 IgE stimulated by a cross-reactive inhalant allergen can result in diverse patterns of alle

13 ed as s-IgE 0.35 kU(A) /L to Phadiatop((R)) (inhalant allergen mix) and/or Fx5 (food allergen mix) at

14 The prevalence of inhalant allergen sensitization increased during childho

15 oxidants, and food contaminants are the main inhalant allergen sources.

16 Sensitization to at least one food or inhalant allergen was found in 319 of 765 (41.7%), and t

17 (637 vs 177 IU/mL, P = .002), and nonfungal inhalant allergen-specific IgE.

18 e and multiplicity of sensitization (food vs inhalant), allergen combinations, and sIgE levels.

19 rticipants had higher median specific IgE to inhalant allergens (41.4 kUA /L, IQR 10.1-118.4) compare

20 AC of the diet and incident sensitization to inhalant allergens (adjusted odds ratio: 0.73, 95% confi

21 e interval [CI]: 0.40-0.91), particularly to inhalant allergens (aOR = 0.64; 95% CI: 0.42-0.99).

22 k estimates for sensitization to food and/or inhalant allergens (aOR = 0.72; 95% CI: 0.42-1.21), whic

23 ecific IgE concentrations to selected common inhalant allergens (dust mite (Dematophagoides farinae),

24 assessment of sensitization to 24 foods, 14 inhalant allergens and 55 allergenic molecules; and conf

25 re the relationship between sensitization to inhalant allergens and adult asthma, we performed two ne

26 IT) and results of allergen-specific IgE for inhalant allergens at 4, 8, 16 and 24 years were analyze

27 fic IgE >/=0.35 kUA /l to common food and/or inhalant allergens at any time point.

28 with specific IgE against 13 common food and inhalant allergens at the ages of (1/2), 1(1/2), 4, and

29 ent of asthma, rhinitis and sensitization to inhalant allergens between 8 and 16 years, and to assess

30 ease the risk of developing sensitization to inhalant allergens from childhood to adolescence.

31 er proteins from pollens and fruits, certain inhalant allergens from house dust mites and cockroaches

32 A clear benefit for inhalant allergens has not yet been shown.

33 sign on the IgE sensitization profile toward inhalant allergens in patients with respiratory allergy

34 tic potential of allergen immunotherapy with inhalant allergens in pollen-related food allergy is not

35 to determine whether early-life exposure to inhalant allergens increases the risk of specific sensit

36 rum IgE antibodies toward four food and four inhalant allergens measured at the age of 5 years.

37 ed by AD skin could promote sensitization to inhalant allergens remains elusive.

38 risk of sensitization to common food and/or inhalant allergens up to early adulthood by 29% (overall

39 Sensitization to food and inhalant allergens was assessed, and autoantibodies were

40 , maternal specific serum IgE against eight inhalant allergens was sampled after the children's birt

41 r positive, negative, judgment, and class of inhalant allergens were 88.7%, 95.1%, 90.8%, and 93.8%,

42 Specific IgE levels for 6 food and 13 common inhalant allergens were assessed in cord blood and 1-yea

43 25(OH)D and specific IgE against four common inhalant allergens were measured by standard procedures.

44 IgE antibodies to food and inhalant allergens were measured in children with active

45 ng function and serum specific IgE levels to inhalant allergens were measured, and information on ast

46 nsitization was assessed by skin prick test (inhalant allergens) and specific IgE levels (food allerg

47 erotoxin IgE antibodies, but not IgE against inhalant allergens, are risk factors for asthma severity

48 th IgE sensitization against common food and inhalant allergens, or specific allergen molecules, in c

49 of the subjects were sensitized to food and inhalant allergens, respectively.

50 been suggested that sensitization to common inhalant allergens, which is developed in a majority of

51 ioimmunosorbent test in response to standard inhalant allergens.

52 s-IgE to food allergen molecules, and <1% to inhalant allergens.

53 Eight infants (0.7%) were sensitized to inhalant allergens.

54 sociated with poly-sensitization to food and inhalant allergens.

55 al IgE and specific IgE to SEs, and food and inhalant allergens.

56 llergens in homes as well as specific IgE to inhalant allergens.

57 assessed by measuring serum IgE specific to inhalant allergens.

58 ed-U shape) associated with sensitization to inhalant allergens.

59 used combining questionnaire data and IgE to inhalant allergens.

60 n of peripheral blood mononuclear cells from inhalant allergic patients was followed by an increased

61 At age 10 years, inhalant allergic sensitization and food-allergic sensit

62 e associated with decreased risks of eczema, inhalant allergic sensitization, and physician-diagnosed

63 gual AIT (SLIT), subcutaneous AIT (SCIT) for inhalant allergies and venom AIT.

64 (SIT) represents an effective treatment for inhalant allergies; however, successful birch pollen SIT

65 ergic sensitization, and physician-diagnosed inhalant allergy (OR range, 0.88-0.94; 95% CI range, 0.7

66 ith an increased risk of physician-diagnosed inhalant allergy (OR, 1.23; 95% CI, 1.08-1.42).

67 sity was associated with physician-diagnosed inhalant allergy (R(2) = 0.001; P = .047).

68 with decreased risks of physician-diagnosed inhalant allergy and asthma (OR range, 0.89-0.86; 95% CI

69 Inhalant allergy can present as chronically severe asthm

70 Development of early asthma endpoints and inhalant allergy during the first 6 years of life seems

71 nhalant allergy without asthma; furthermore, inhalant allergy in one parent also conferred additional

72 istently associated with physician-diagnosed inhalant allergy in school-age children and less consist

73 s than in families where only one parent had inhalant allergy without asthma; furthermore, inhalant a

74 ly separated the cases into four groups: (i) inhalant allergy, (ii) fungal sensitization with or with

75 PBMCs from subjects with food allergy, inhalant allergy, and no allergy were obtained on the ba

76 of opportunity for prevention of asthma and inhalant allergy.

77 es and specific IgE levels against 12 common inhalant and 10 food allergens were assessed longitudina

78 lagellated chambers that are connected to an inhalant and exhalant canal system.

79 IgE and IgG responses to 47 inhalant and food allergen components were analyzed in s

80 were linked to levels of IgE against common inhalant and food allergens at 4 and 8 years of age.

81 s were assessed simultaneously for 16 common inhalant and food allergens at age (1/2), 1(1/2), 4, and

82 ssociation of specific IgE levels to several inhalant and food allergens compared with HEU participan

83 disease with a Th2 inflammatory response to inhalant and food allergens that cause an eosinophilic i

84 the overall risk of sensitization to common inhalant and food allergens up to school age, but sensit

85 Allergic sensitization against 28 inhalant and food allergens was assessed at (1/2), 1(1/2

86 Allergic sensitization against common inhalant and food allergens was determined longitudinall

87 /= 0.35 kU/l to at least one of 15 evaluated inhalant and food allergens), current rhinitis, and curr

88 by skin-prick testing with a panel of common inhalant and food allergens.

89 was assessed by skin prick test (SPT) using inhalant and food allergens.

90 re tested for serum specific IgEs (sIgEs) to inhalant and food allergens; participants 6 years or old

91 ement between the two methods for diagnosing inhalant and food allergic sensitization at the four age

92 by skin prick tests, and physician-diagnosed inhalant and food allergy by a postal questionnaire.

93 Risk factors include inhalant and occupational allergens, as well as genetic

94 al triggers (Hymenoptera venoms, food, drug, inhalant and others) and risk factors at diagnosis and d

95 ated with allergic sensitization, especially inhalant and seasonal allergens, rather than food allerg

96 Serum immunoglobulin E against eight common inhalant and six food allergens was assessed at ages 4,

97 oss-reacting allergenic structures shared by inhalants and foods.

98 ing for use of non-glucocorticoid-containing inhalants, and confirmed results by addressing confoundi

99 ee of the 10 substances considered (alcohol, inhalants, and heroin).

100 pping molecular sites of action for ethanol, inhalants, and volatile anesthetics on glycine receptors

101 en with any atopic disease and children with inhalant- and food-allergic sensitization or atopic derm

102 Information on atopic dermatitis, inhalant- and food-allergic sensitization, asthma lung f

103 l diseases, children with atopic dermatitis, inhalant-, and food-allergic sensitization had higher me

104 glycemic clamps were performed in dogs under inhalant anesthesia with deep hindlimb lymphatic samplin

105 rences were reflected in the larger seasonal inhalant atopy class in Finland, although composition of

106 non-neuronal cell populations involved with inhalant biotransformation, detoxification, and maintena

107 ood (egg, cow's milk, peanut, wheat, soy) or inhalant (birch, timothy grass, dog, and cat) allergen b

108 ood (egg, cow's milk, peanut, wheat, soy) or inhalant (birch, timothy grass, dog, and cat) allergen b

109 ions: an unsensitized class, a food class, 2 inhalant classes differentiating between seasonal and pe

110 ng effects of ethanol but not anesthetics or inhalants, demonstrated antagonism of anesthetic and inh

111 Inhalant (e.g., toluene) misuse is linked to behavioral

112 its caused by toluene.SIGNIFICANCE STATEMENT Inhalants (e.g., toluene) are an understudied class of d

113 s, demonstrated antagonism of anesthetic and inhalant effects on this receptor.

114 with ineffective repair in response to toxic inhalants (especially cigarette smoke).

115 ring of vaccines of pharmaceutical grade for inhalant, food, and venom allergens.

116 Use of inhalants for obstructive airway diseases (PR = 0.79; 95

117 nt of metabolic syndrome-related conditions, inhalants for obstructive airway diseases and glucocorti

118 Inhalants have the potential to result in serious organ

119 ced by airway sensitization and challenge to inhalant house dust mite (HDM), we demonstrate that the

120 nizes the nasopharynx and is thus exposed to inhalants, including cigarette smoke.

121 Inhalants, including toluene, target the addiction neuro

122 turn to lung homeostasis following high dose inhalant lipopolysaccharide (LPS, 10-100 mug) exposure w

123 ecovery processes following acute, high dose inhalant LPS exposure.

124 Environmental and occupational inhalants may induce a large number of pulmonary disease

125 individuals may be especially susceptible to inhalant occupational exposures.

126 ns, yet preclinical studies of the effect of inhalants on higher-order cognition are limited.

127 egories (alcohol-, cannabis-, hallucinogen-, inhalant-, opioid-, sedative-, stimulant-, and other sub

128 related to alcohol, cannabis, hallucinogens, inhalants, opioids, sedatives, stimulants, and other sub

129 children concomitantly sensitized to common inhalant or food allergens (-136.9 ml; 95% confidence in

130 licited by the negative control to any of 10 inhalant or food allergens.

131 d particularly in those sensitized to common inhalant or food allergens.

132 eding with childhood allergic sensitization, inhalant or food allergy and eczema, and whether any ass

133 non-medical formulations including edibles, inhalants or topicals as a preventative or treatment the

134 e, cannabis, stimulants, sedatives, opioids, inhalants, or performance enhancers).

135 antibodies to a mix of common food (fx5) and inhalant (Phadiatop) allergens were analysed at 4, 8, 16

136 Assays for inhalants provide greater opportunities for accurate dia

137 ce type, the cost ranged from $4 million for inhalant-related disorders to $7.6 billion for alcohol-r

138 Inhalants remain one of the most commonly abused substan

139 as the milk and egg dominated and peanut and inhalant(s) groups were not (ORs of 1.6 [95% CI, 0.8-3.0

140 and egg dominated" (15.3%), and "peanut and inhalant(s)" (5.1%).

141 autia obeum was associated with reduced food/inhalant sensitization and genetic variants near the MAR

142 wheeze) and atopic (atopic dermatitis, food/inhalant sensitization) outcomes.

143 Since toluene and other abused inhalants share many behavioral effects with ethanol, it

144 All three inhalants significantly and reversibly enhanced neurotra

145 scles (OSMs), which control the exhalant and inhalant siphons, respectively, also requires Mrf We cha

146 ampaign pursuing the identification of novel inhalant small-molecule phosphatidylinositol 3-kinase (P

147 nsidered these to be avoidance receptors for inhalants that, when activated, lead to ASM contraction

148 In addition to known medical consequences of inhalant use (including death), other risks associated w

149 ncluding death), other risks associated with inhalant use and addiction include addiction to other su

150 d psychological damage that can be caused by inhalant use argues for much greater attention to be pai

151 pioid, sedative/tranquilizer, and/or solvent/inhalant use disorders.

152 dels have cast light on how reinforcement of inhalant use occurs, and on mechanisms of development of

153 consequences, pharmacology, and etiology of inhalant use, and how we might develop preventive and ma

154 y in the context of rising air pollution and inhalant use, are an active area of research.

155 Participants were grouped by inhalant use, with 8% e-cigarette users, 12% conventiona

156 ly impact sleep quality and may be caused by inhalant use.